An experimental investigation of the ability of the chondroitinsulphate preparation produced from cattle tracheas, of rumalon and chonsuride to stimulate the regeneration of cutaneous coverings in case of their injury was carried out. A strength of the surgical cicatrix and its elongation at rupture in two weeks' injections of chondroitinsulphate increased in comparison with control. A stimulating effect of chondroitinsulphate to regeneration of flesh wound in case of local single action didn't differ essentially from the effect of chonsuride. In case of application of the preparations, an area of wound for the rats received chondroitinsulphate was already on the eighth day twice as less in comparison with the animals treated with chonsuride. Thus, a stimulating effect of chondroitinsulphate preparation to the regeneration of damaged cutaneous coverings by both parenteral and local administration was shown.
ChemInformVolume 20, Issue 18 Heterocyclic Compounds ChemInform Abstract: Synthesis and Pharmacological Properties of Heterocyclic Prostaglandin Analogues (V), (VI), (VII). V. A. DOMBROVSKII, V. A. DOMBROVSKII VNII tekhnol. krovezamenitelei i gormonanl'n. prep., MoskvaSearch for more papers by this authorE. V. GRACHEVA, E. V. GRACHEVA VNII tekhnol. krovezamenitelei i gormonanl'n. prep., MoskvaSearch for more papers by this authorE. P. PROKOF'EV, E. P. PROKOF'EV VNII tekhnol. krovezamenitelei i gormonanl'n. prep., MoskvaSearch for more papers by this authorL. V. SOROKIN, L. V. SOROKIN VNII tekhnol. krovezamenitelei i gormonanl'n. prep., MoskvaSearch for more papers by this authorL. V. KADYSHEVA, L. V. KADYSHEVA VNII tekhnol. krovezamenitelei i gormonanl'n. prep., MoskvaSearch for more papers by this authorV. E. BELAI, V. E. BELAI VNII tekhnol. krovezamenitelei i gormonanl'n. prep., MoskvaSearch for more papers by this authorP. M. KOCHERGIN, P. M. KOCHERGIN VNII tekhnol. krovezamenitelei i gormonanl'n. prep., MoskvaSearch for more papers by this author V. A. DOMBROVSKII, V. A. DOMBROVSKII VNII tekhnol. krovezamenitelei i gormonanl'n. prep., MoskvaSearch for more papers by this authorE. V. GRACHEVA, E. V. GRACHEVA VNII tekhnol. krovezamenitelei i gormonanl'n. prep., MoskvaSearch for more papers by this authorE. P. PROKOF'EV, E. P. PROKOF'EV VNII tekhnol. krovezamenitelei i gormonanl'n. prep., MoskvaSearch for more papers by this authorL. V. SOROKIN, L. V. SOROKIN VNII tekhnol. krovezamenitelei i gormonanl'n. prep., MoskvaSearch for more papers by this authorL. V. KADYSHEVA, L. V. KADYSHEVA VNII tekhnol. krovezamenitelei i gormonanl'n. prep., MoskvaSearch for more papers by this authorV. E. BELAI, V. E. BELAI VNII tekhnol. krovezamenitelei i gormonanl'n. prep., MoskvaSearch for more papers by this authorP. M. KOCHERGIN, P. M. KOCHERGIN VNII tekhnol. krovezamenitelei i gormonanl'n. prep., MoskvaSearch for more papers by this author First published: May 2, 1989 https://doi.org/10.1002/chin.198918202AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article. Volume20, Issue18May 2, 1989 RelatedInformation
AbstractThe amino heterocyclus (I), the base of the drug amiridin (I·HCl·H2O), is transformed into the derivatives (III), (V), and (IX) as shown in the reaction scheme.