"卫气津营血精神"七纲理论由四川省十大名中医吴康衡教授在"卫气营血"理论基础上提出,系统总结了外感温热类疾病各个阶段的诊治方药.过敏性紫癜是儿科常见疾病之一,临床常表现出类似于温病的证候特点.本文探讨了以"卫气津营血精神"七纲理论治疗过敏性紫癜的方法,依据过敏性紫癜各个阶段的临床表现,将过敏性紫癜治法分为解表透卫、清热泻脾、凉润生津、清热透营、清热凉血、滋阴生精、补气养神七类,常用木贼宣痹汤、泻黄散、竹叶石膏汤、清营汤、五草五炭汤、加减复脉汤、清心莲子饮等方剂加减,进一步丰富"卫气津营血精神"七纲理论的临床应用.

目的 探究儿童幽门螺旋杆菌(Hp)感染和过敏性紫癜(HSP)的发病是否具有相关性,为探讨HSP的病因病理提供依据.方法 系统检索 CNKI、WanFang Data、MEDLINE、Cochrane Library、EMbase、Web of Science、VIP 等数据库中有关 Hp 感染与儿童HSP相关性的研究文献,检索时限为建库起至2022年12月.使用Endnote整理筛选文献,文献质量评价采用纽卡斯尔渥太华量表.研究基本特征、效应量以及计算效应量所需相关数据由2名独立研究人员进行提取.采用RevMan5.3软件和STATA16.0软件进行Meta分析,使用随机效应模型对数据进行计算.结果 共纳入15项病例对照研究,包括2676例研究对象,纳入研究NOS评分为6～7分.Meta分析显示,儿童HSP组Hp感染阳性率高于健康儿童对照组,差异有统计学意义(OR=4.32,95％CI:3.07～6.10,P＜0.000 01).考虑到不同检测指标、地域对研究的异质性产生影响,进行亚组分析及Meta回归分析,提示这2个因素未被确定为异质性的潜在危险因素.腹型和肾型HSP合并结果均提示腹型和肾型紫癜发病可能与Hp感染有关,但不能明确其相关性是否比其它类型紫瘢更强,HSP儿童中腹型紫癜(OR=5.35,95％CI:2.59～11.05,P=0.000),肾型紫癜(OR=5.30,95％CI:1.05～26.61,P=0.043)可能与Hp感染有关.结论 儿童Hp感染和HSP发病存在一定相关性,其与HSP分型的相关性尚不明确,儿童Hp感染可能是HSP的发病原因之一,甚至可能是病理机制中的重要环节,但以上结论有待更多多中心、大样本、高质量的研究以得出更可靠的结论.

目的 了解贵阳市云岩区基层医疗机构消毒质量状况,为卫生行政部门监督提供依据.方法 采用现场采样、微生物和理化检测方法,对在云岩区卫生局注册登记并营业的全部医疗机构进行消毒质量监测.结果 2015年共检测样品3 092份,检测合格3 002份,总合格率为97.03％,其中使用中的消毒液、紫外线灯管照度、室内空气、室内物体表面和医护人员手样的合格率分别是100.00％、99.10％、86.36％、99.22％和99.25％.结论 贵阳市云岩区基层医疗机构的消毒质量状况整体较好,但仍存在基层医疗机构的室内空气消毒质量较差的问题,卫生行政部门应加强薄弱环节的监督.

<正>卫生部在2000年曾经发过《出血时间、凝血时间检验方法操作规程的通知》[1]《.通知》主要内容:(1)停止使用出血时间测定项目的Duke法,但出血时间的检验项目不废除。若临床怀疑血管壁异常所致出血性疾病时(如血管性血友病、单纯性紫癜、过敏性紫癜等),可使用出血时间测定器法检测出血时间。

目的初步了解到该院体检的幼儿园儿童HBV的感染状况,分析原因,提出应对措施。方法对3982例儿童用酶联免疫吸附试验(ELISA)检测血清乙肝标志物。结果乙肝表面抗原(HBsAg)阳性率为0.3%(12/3 982),乙肝表面抗体(抗-HBs)阳性率为63.46%(2 529/3 982),两对半全阴性儿童1 439例,占36.14%;无论单一乙肝标志物还是乙肝5项不同模式比较,男、女儿童比较差异均无统计学意义(P>0.05)。结论体检的幼儿园儿童HBV携带率远低于我国成人HBV携带率,男、女儿童在感染HBV、获得免疫力或无免疫力方面均无统计学意义。

耦联因子6(CF6)是线粒体ATP合成酶的1个亚基,存在于血管内皮细胞膜上。通过不同的途径引起前列环素合成受抑、NO释放减少、动脉粥样硬化因子增加,造成血管内皮功能异常,在血管相关性疾病(如高血压、冠心病)中扮演关键角色。近年来发现,糖尿病患者体内CF6明显升高,导致糖尿病血管病变。现简要综述CF6的结构功能、信号转导系统对糖尿病及血管病变的作用。

[Objective] To study the changes of drug resistance of Acinetobacter baumannii which were isolated from clinical specimens during the four-year period in our hospital and to supply references for rational use of drugs in clinic.[Methods] Retrospectively analyzed and concluded 256 strains of Acinetobacter baumannii which were isolated from a variety of clinical specimens from 2005 to 2008.[Results] The resistance rates of 15 kinds of antibiotics were increasing year after year.These antibiotics were Ampicillin /Sulbactam,Piperacillin /Tazobactam,Cefepime,Ceftazidime,Gentamicin and Sulfamethoxazole /Trimethoprim.What' s more,the resistance rates of Acinetobacter baumannii to antibiotics kept a high level from 2005 to 2008,which were Cefazolin,Ampicillin and Aztreonam.And the rates were 85.00%-100%,65.82%-100% and 68.35%-98.00%,respectively.Moreover,in ICUs,the resistance rate to Imipenem reached 63.41% and the resistance rates to most antibiotics(11 kinds) were all higher than 80% in 2008.[Conclusion] During the four-year period,the resistance rate of Acinetobacter baumannii to most antibiotics is increasing year after year and the resistance rates in ICUs are higher than those in non-ICUs obviously.

尿液分析仪是试纸法与仪器法相结合的产物,因其操作简单、灵敏度高、而且快捷方便,现已在临床得到广泛应用.但尿液分析仪因受各种因素的影响和方法学的限制,常常出现错误的检测结果.为此,用尿液分析仪及传统的显微镜检查对尿液中红细胞的检测结果进行了分析对比,结果报道如下.

Objective To understand the status grasping the labor knowledge by pregnant wemen and their husbands,to provide the bases for implementing the prelabor health education,to make them choose smooth child- birth rationally,to protect them away the risk in delivery and to reduce the influence of social factors in rising caesar- ean section.Methods A district of Chongqing was extracted as study area by radom cluster sampling mothed.599 pregnant women and 242 husbands were selected from June,2006 to August,2006 in 13 hospitals on this district. Self administrated questionnaire was used to investigate the knowledge related delivery and childbirth way,sources of the knowledge and their liking knowledge.Results 283 pregnant women had attended the study of prenatal educa- tion,316 pregnant women had not attended.107 husbands accompanied their wives to attend the study,127 had not.Conclusion The construction of pregnant women school and the propaganda and prenatal education on the knowledge of childbirth way for pregnant women and their husbands should be strengthened in order to raise the ca- pability of self health care and reduce the ratio of caesarean section.