ETHNOPHARMACOLOGICAL RELEVANCE:Yuxintong capsule, a traditional Chinese patent medicine, has been widely used in the treatment of coronary heart disease (CHD). However, whether it can improve cardiopulmonary fitness (CRF) in patients with CHD remains unclear. AIM OF THE STUDY:To evaluate the efficacy and safety of Yuxintong capsule in CRF in patients with stable CHD. MATERIALS AND METHODS:A multicentre, randomized, double-blind, placebo-controlled, parallel-group trial was conducted in 13 hospitals in China from March 2021 to November 2021, and 404 patients with stable CHD were randomly assigned to receive either Yuxintong capsule and conventional Western medicine (Yuxintong group) or placebo and conventional Western medicine (placebo group) in a 1:1 ratio for 12 weeks (ChiCTR2000041293, December 23, 2020). The primary outcomes were peak oxygen uptake (VO2peak) and anaerobic threshold (AT). The secondary outcomes were metabolic equivalents (METs), duration and onset time of 1-mm ST-segment depression on electrocardiography (ECG), and 36-Item Short Form Health Survey (SF-36) scores. The main safety indicators included complete blood count, urinalysis, liver function, renal function, coagulation function, and 12-lead electrocardiogram. And adverse events were recorded throughout the trial. RESULTS:369 patients, 187 in the Yuxintong group and 182 in the placebo group, were finally included for analysis. Compared with placebo group, 12-week treatment with Yuxintong showed an improvement in AT (0.98 ± 2.88 vs. 0.12 ± 2.79 mL kg-1·min-1; LSMD, 0.80 [95 % CI: 0.28 to 1.32]; P < 0.025), and general health (13.61 ± 15.13 vs. 8.29 ± 14.14; LSMD 5.30, [95 % CI: 2.33 to 8.31]; P < 0.05) and vitality scores (12.46 ± 11.32 vs. 6.01 ± 11.41; LSMD 6.43, [95 % CI: 4.13 to 8.31]; P < 0.05) on SF-36 scale. The other outcomes did not significantly differ between the two groups. The adverse events were similar between the two groups. CONCLUSIONS:Yuxintong capsule, as an adjunctive therapy to conventional treatment, improved AT, and general health and vitality scores on SF-36 scale in patients with stable CHD. However, the improvements in VO2peak, METs, and the duration and onset time of 1-mm ST-segment depression on ECG were not statistically significant.

BackgroundAbdominal aortic calcification (AAC) serves as a reliable predictor of future cardiovascular incidents. This study investigated the association between dietary niacin intake and AAC in US adults.MethodsIn this study, we conducted a cross-sectional study of 2,238 individuals aged 40 years and older using data from the National Health and Nutrition Examination Survey (NHANES) 2013–2014. AAC was evaluated using the Kauppila scoring system through dual-energy X-ray absorptiometry. Daily niacin intake was calculated by averaging the two dietary recalls and classified in tertiles for analysis. In this study, multiple regression analyses and smoothed curve fitting were used to examine the relationship between dietary niacin intake and AAC, subgroup analyses and interaction tests were used to assess the stability of this relationship across different segments of the population, and forest plots were used to present the results. In addition, we validated the predictive performance of dietary niacin intake on the risk of severe AAC through Receiver Operating Characteristic (ROC) curve analysis.ResultsAmong 2,238 participants aged >40 years, the results showed that the higher dietary niacin intake group was associated with lower AAC score (β = −0.02, 95% CI: −0.04 – −0.01), and a lower risk of severe AAC (OR = 0.97, 95% CI: 0.96–0.99). In the fully adjusted model, the higher tertile group was associated with lower AAC score (β = −0.37, 95% CI: −0.73 – −0.02; P for trend = 0.0461) and a lower risk of severe AAC (OR = 0.60, 95% CI: 0.38–0.93; P for trend = 0.0234). The relationship between dietary niacin intake and AAC differed significantly between diabetic and non-diabetic population. The ROC curve analysis revealed that the area under the curve (AUC) for predicting severe AAC risk based on dietary niacin intake was 0.862, indicating good predictive performance.ConclusionHigher dietary niacin intake group was associated with lower AAC score and a lower risk of severe AAC. Our findings suggest that dietary niacin intake has the potential to offer benefits in preventing AAC in the general population.

BackgroundThe relationship between serial changes in physical activity and the risk of developing atrial fibrillation (AF) has been rarely studied.ObjectivesTo evaluate the association between changes in physical activity over time and the incidence of AF.MethodsA total of 11,828 participants without AF at baseline (visit 1: 1987–1989) from the ARIC Study were included. Physical activity was measured using the modified Baecke Physical Activity Questionnaire at three different visits between 1987 and 2013. Physical activity trajectories over 25 years were identified using latent class trajectory modeling. The primary outcome was the incidence of AF. Multivariable Cox hazard regression models were used to evaluate the relationship between physical activity trajectories and the incidence of AF.ResultsOver a median follow-up of 24 years, 2,108 AF cases (17.8%) occurred. Four distinct physical activity trajectories were identified: light [n = 5,266 (43.3%)]; reduced moderate [n = 3,583 (29.0%)]; moderate [n = 2,691 (25.0%)]; and vigorous intensity [n = 288 (2.8%)]. Compared to the light group, the hazard ratio (HR) and 95% confidence interval (CI) for AF were 1.18 (1.07–1.30) (p < 0.001) for the reduced moderate group, 0.61 (0.53–0.70) (p < 0.001) for the moderate group, and 0.82 (0.59–1.12) (p = 0.21) for the vigorous group, after multivariate adjustments.ConclusionMaintaining moderate levels of physical activity is associated with a lower risk of AF, while a decrease in activity from moderate to light levels increases the risk. These findings highlight the importance of sustaining adequate physical activity levels for the prevention of AF.

In recent years, progress has been made in general practice education research with the integration of narrative medicine and general practice. The narrative medicine is conducive to upgrading the abilities of general practice residents in doctor-patient communication, disease management and clinical decision makings; it also conducive to improvement of their humanistic quality and doctor-patient relationship. This article reviews the application of narrative medicine in the general practice residency training, and discusses relevant problems and countermeasures.

Objective: To evaluate the efficacy and safety of oral anticoagulants for older adult patients with atrial fibrillation (AF).Design: Pairwise and network meta-analyses.Setting and Participants: Patients with AF aged & GE;75 years.Methods: PubMed, Embase, and the Cochrane library were searched for published randomized controlled trials and adjusted observational studies evaluating the use of a non-vitamin K antagonist oral anti-coagulants (NOACs), vitamin K antagonist, or antiplatelet drug for the prevention of stroke. The primary efficacy and safety outcomes were the composite of stroke and systemic embolism (SSE) and major bleedings.Results: This study included 38 studies enrolling 1,022,908 older adult patients with AF. Results from pairwise meta-analyses showed that NOACs were superior to warfarin for all outcomes, except that dabigatran increased the risk of gastrointestinal (GI) bleedings. Aspirin was associated with a higher risk of SSE and ischemic stroke than warfarin or NOACs. Results of network meta-analyses indicated that apixaban significantly reduced the risk of SSE, major bleedings, and GI bleedings than warfarin, rivar-oxaban, and dabigatran. Apixaban, edoxaban, rivaroxaban, and dabigatran reduced the risk of ischemic stroke and intracranial bleeding compared to warfarin. Dabigatran showed lower risk of all-cause mortality than warfarin and of intracranial bleeding than rivaroxaban.Conclusions and Implications: NOACs are of at least equal efficacy, or even superior to warfarin. The safety profile of individual NOAC agents was significantly different, as apixaban performs better than the other oral anticoagulants in reducing major bleeding and GI bleeding, whereas dabigatran increased the risk of GI bleeding.& COPY; 2023 AMDA -The Society for Post-Acute and Long-Term Care Medicine.

Intestinal flora always maintains a dynamic balance in the health human body, and it is interdependent, inhibitory and ompetitive with the body. With the increasingly progressive level of medicine and biotechnology, more and more studies have found that the effect traditional Chinese medicine on the treatment of multisystem diseases is related to adjustment of the imbalance of intestinal flora. This paper summarizes the studies on the impact of traditional Chinese medicine on intestinal flora in recent years. It is found that traditional Chinese medicine plays an important role in multisystem diseases through improving the abundance and evenness of intestinal flora, affecting metabolic pathways and metabolites, and regulating the intestinal mucosal barrier.

目的 探讨不同程度心力衰竭合并贫血患者的病因及合并疾病特点.方法 选取首都医科大学附属北京安贞医院2018年1月至2020年12月收治的2180例心力衰竭合并贫血患者.根据纽约心脏病协会心功能分级将患者分为轻度心力衰竭组(Ⅰ～Ⅱ级,999例)和重度心力衰竭组(Ⅲ～Ⅳ级,1181例).记录患者年龄、性别、合并疾病及引起心力衰竭的主要病因.采用二元Logistic回归模型分析心力衰竭合并贫血患者发展为重度心力衰竭的危险因素.结果 二元Logistic回归分析结果显示年龄≥60岁(比值比=2.210,95％置信区间:1.826～2.675)、肺部感染(比值比=2.318,95％置信区间:1.717～3.111)、肾脏病(比值比=1.646,95％置信区间:1.312～2.065)、消化道出血(比值比=1.620,95％置信区间:1.044～2.515)、原发性心肌病(比值比=4.665,95％置信区间:2.504～8.694)是心力衰竭合并贫血患者发展为重度心力衰竭的危险因素(均P<0.05).结论 年龄≥60岁、肺部感染、肾脏病、消化道出血以及原发性心肌病是心力衰竭合并贫血患者发展为重度心力衰竭的危险因素.

目的 探讨心功能不全合并贫血患者发生急性心肌梗死的相关疾病因素.方法 选取2018年1月至2020年12月于首都医科大学附属北京安贞医院住院的心功能不全合并贫血患者3 040例,根据是否发生急性心肌梗死分为急性心肌梗死组(322例)和非急性心肌梗死组(2 718例).比较2组患者年龄、性别、合并疾病等临床资料,分析患者发生急性心肌梗死的疾病因素.结果 急性心肌梗死组年龄、合并糖尿病、高血压、高脂血症、肾脏病、消化道出血比例均高于非急性心肌梗死组[(68±12)岁比(59±15)岁、53.1％(171/322)比24.5％(666/2 718)、70.5％(227/322)比53.5％(1 454/2 718)、59.6％(192/322)比26.0％(706/2 718)、58.7％(189/322)比30.1％(817/2 718)、15.2％(49/322)比5.5％(149/2 718)],合并心房颤动、瓣膜病比例均低于非急性心肌梗死组[14.6％(47/322)比19.4％(527/2 718)、27.0％(87/322)比54.5％(1 480/2 718)],差异均有统计学意义(均P＜0.10).Logistic回归分析结果显示,年龄≥60岁、合并糖尿病、高脂血症、肾脏病、消化道出血是心功能不全合并贫血患者发生急性心肌梗死的独立危险因素(均P＜0.05).结论 在心功能不全合并贫血患者中,年龄≥60岁患者合并有糖尿病、高脂血症、肾脏病、消化道出血时更容易发生急性心肌梗死.

目的 观察肾性继发性甲状旁腺功能亢进症(secondary hyperparathyroidism,SHPT)患者行甲状旁腺全切除术(total parathyroidectomy,TPTX)或 TPTX 联合自体移植术(total parathyroidectomy with autotransplantation,TPTX+AT)后血钙、血磷及血清全段甲状旁腺激素(intact parathyroid hormones,iPTH)、碱性磷酸酶(alkaline phosphatase,ALP)水平变化,探讨其治疗效果和安全性.方法 肾性SHPT患者62例,行TPTX或TPTX+AT治疗.记录手术成功率及术后并发症发生情况;比较术前及术后1、3、6个月时血钙、血磷及血清iPTH、ALP水平;比较术前及术后6个月时骨痛视觉模拟评分(visual analogue scale,VAS)、皮肤瘙痒及睡眠障碍发生率;随访至2020年4月,记录术后SHPT复发及持续性甲状旁腺功能低下发生情况.结果 62例患者中24例行TPTX,38例行TPTX+AT,手术成功率100％,行TPTX+AT者移植物存活率为86.8％,术后均未发生切口感染、喉部感觉神经丧失、失音等并发症,无围术期死亡.血钙、血磷及血清iPTH、ALP水平在术后1个月[(2.26±0.20)mmol/L、(1.09±0.29)mmol/L、73.74(64.50,86.26)ng/L、223.18(44.87,318.86)u/L]、3 个月[(2.26±0.21)mmol/L、(1.28±0.25)mmol/L、72.37(64.13,84.40)ng/L、131.98(43.52,199.61)u/L]、6 个月[(2.27±0.22)mmol/L、(1.33±0.24)mmol/L、71.11(60.06,83.04)ng/L、104.78(35.36,154.91)u/L]时均低于术前[(2.66±0.15)mmol/L、(2.89±0.70)mmol/L、1 277.32(1 012.35,1 423.85)ng/L、567.68(445.10,741.50)u/L](P＜0.05);术后 3、6 个月时血磷水平均高于术后 1个月时(P＜0.05),血清ALP水平均低于术后1个月时(P＜0.05);术后6个月时血磷水平高于术后3个月时(P＜0.05),血清iPTH、ALP水平均低于术后3个月时(P＜0.05).术后6个月时皮肤瘙痒(4.84％)、睡眠障碍(3.23％)发生率及骨痛 VAS 评分[(1.96±0.91)分]均低于术前[80.65％、69.35％、(5.12±2.29)分](P＜0.05).随访至2020年4月,SHPT复发9例,出现持续性甲状旁腺功能低下5例.结论 肾性SHPT患者行TPTX或TPTX+AT可有效缓解临床症状,降低血钙、血磷及血清iPTH、ALP水平,且围术期并发症、持续性甲状旁腺功能低下发生率及SHPT复发率低.

心血管疾病是导致全球性死亡的主要病因[1],截止到2030年约有2330万例死于心血管疾病,冠心病是最主要的心血管疾病之一,其发病率呈上升趋势[2],因此冠心病诊疗长期以来一直是学者们重点关注内容.传统诊疗冠心病方案的提高依赖于大型随机对照试验的严格对比和发现,更新效率较低.数据挖掘技术可解决这一问题,具有时间短、效率高的作用.该技术通过对大量电子病历数据进行整理、分析,辅助冠心病的诊疗[3-4].数据挖掘技术主要包括两大类算法:监督学习算法和无监督学习算法.监督学习主要通过已有的训练样本去训练得到一个最优模型,常见的有监督学习算法:决策树、神经网络、支持向量机、线性回归、KNN、朴素贝叶斯、随机森林等算法;无监督学习是在没有标签的数据里面发现潜在一些结构的方式,主要的无监督学习算法主要有聚类、降维、关联规则分析等算法.本文将对这两大类算法在冠心病诊疗中的应用进展进行归纳整理.

ObjectiveThe objective of this study was to measure the efficacy of various types and dosages of statins on C-reactive protein (CRP) levels in patients with dyslipidemia or coronary heart disease.MethodsRandomized controlled trials were searched from PubMed, Embase, Cochrane Library, OpenGray, and ClinicalTrials.gov. We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines for data extraction and synthesis. The pairwise meta-analysis compared statins and controls using a random-effects model, and a network meta-analysis compared the types and dosages of statins using the Bayesian random-effects model. The PROSPERO registration number is CRD42021242067.ResultsThe study included 37 randomized controlled trials with 17,410 participants and 20 interventions. According to the pairwise meta-analysis, statins significantly decreased CRP levels compared to controls (weighted mean difference [WMD] = −0.97, 95% confidence interval [CI] [−1.31, −0.64], P < 0.0001). In the network meta-analysis, simvastatin 40 mg/day appeared to be the best strategy for lowering CRP (Rank P = 0.18, WMD = −4.07, 95% CI = [−6.52, −1.77]). The same was true for the high-sensitivity CRP, non-acute coronary syndrome (ACS), <12 months duration, and clear measurement subgroups. In the CRP subgroup (rank P = 0.79, WMD = −1.23, 95% CI = [−2.48, −0.08]) and ≥12-month duration subgroup (Rank P = 0.40, WMD = −2.13, 95% CI = [−4.24, −0.13]), atorvastatin 80 mg/day was most likely to be the best. There were no significant differences in the dyslipidemia and ACS subgroups (P > 0.05). Node-splitting analysis showed no significant inconsistency (P > 0.05), except for the coronary heart disease subgroup.ConclusionStatins reduced serum CRP levels in patients with dyslipidemia or coronary heart disease. Simvastatin 40 mg/day might be the most effective therapy, and atorvastatin 80 mg/day showed the best long-term effect. This study provides a reference for choosing statin therapy based on LDL-C and CRP levels.

目的 了解医联体全科医学基层实践基地师资现状,为更好地发挥牵头医院的优势及带头作用,以期切实地不断加强基层师资建设.方法 2021年4月对北部医联体基层实践基地师资进行调查,内容包括一般情况、职业素养、临床工作能力、带教能力和可持续发展能力.共发放调查问卷16份,收回16份,回收率100％.结果 在职业素养中,基层师资对自身职业道德评分较高(9.15±0.99),对全科医学的热爱程度评分为8.69±1.11分,对教学工作的热爱评分为8.23±1.09分;在临床工作能力中,对急危重症初步处置和转诊评分较低(7.92±1.26);在带教能力中,教案书写、教学方法与技巧、门诊带教和基本技能带教评分较低,分别为7.69±1.38、7.69±1.44、7.77±1.24和7.77±1.30;在可持续发展能力中,科研意识和论文撰写评分较低,分别为7.23±1.54和6.77±1.59.结论 北部医联体全科医学基层实践基地师资较为缺乏,带教能力需要进一步提升,可持续发展能力有待不断提高.

目的 为促进临床医学本科生社区医防融合能力的提升,对学生进行预防医学和公共卫生相关知识的培训与研究.方法 2020年5—6月对2017级临床医学专业62名本科生进行慢病和传染病防控、突发公共卫生事件应急处置等相关内容培训并问卷调查.共发放调查问卷62份,收回57份,回收率91.94％.结果 92.98％ 的学生认为本次培训的必要性很大和较大;94.74％的学生认为本次培训收获很大和较大.77.19％的学生表示对本次培训慢病防控专题的收获很大和较大;91.23％的学生表示对本次培训传染病防控专题的收获很大和较大;94.74％的学生表示对本次培训个人防护专题的收获很大和较大;75.44％的学生表示对应急演练专题的收获很大和较大;98.25％的学生参加过穿脱隔离衣的实操;35.09％的学生参与过相关突发公共卫生事件的应急演练.结论 临床医学本科生对本次培训非常认可,在慢病防控培训方面应进一步突出社区特色,在应急演练培训中增加现场实操环节.

随着"健康中国2030"规划纲要的逐步落实,医疗卫生体制改革正在逐渐深化,社区医疗卫生服务规模也在不断扩大,全科医生的重要性日益突显.国家急需培养大量高素质的全科医生,来满足社会需求,以增加人民对医疗卫生服务的满意度和获得感.培养高素质的全科医生,应从社区轮转的大学生抓起.通过翻阅文献,结合临床工作经验,浅析社区医疗机构对轮转大学生的培养:应该以提高"四种能力"、培养"三种素质"、达到"三个目标"为指导思想,全面提高轮转大学生的全科能力.四种能力包括:职业道德、专业能力、人际沟通与团队合作能力、教学与科研能力,三种素质包括:职业素质、人文素质、综合素质,三个目标是:医病、医身、医心.

目的:通过调研分析北京某农村地区老年阴道炎患病现状与就诊情况,提出可行的解决方法,为更好地提升家庭医生服务质量提供依据.方法:选取2020年7月-2020年8月对2020年辖区内参加老年人体检的老年女性,进行老年性阴道炎筛查,对诊断为老年性阴道炎的患者,关于对就诊情况进行现场调研和问卷调查.结果:①本次共对辖区内1023名老年女性进行了老年性阴道炎的筛查,共有278名老年人诊断有老年性阴道炎,患病率为27.17％;②其中有过就诊经历的为91人,占总人群的32.73％;③调查问卷显示,经济原因、就医不便、对疾病认识不足是影响老年性阴道炎患者就诊的主要原因.结论:老年性阴道炎在农村地区发病率高、就诊率低,家庭医生工作中应针对该人群加强社区宣传教育,提高患者对疾病的认识,引导及时就医、规范治疗.

Objective To analyze the effect of Xuezhikang on the markers of the serum lipid levels of cholesterol synthesis and absorption in early menopausal women with hypercholesterolemia, and preliminarily explore its lipid-lowering mechanism. Methods A total of 90 early menopausal women with hypercholesterolemia were enrolled from December, 2014 to May, 2016 from Beijing Anzhen Hospital, Capital Medical University, who were randomly allocated to receive Xuezhikang (1200 mg/d, orally) or atorvastatin (10 mg/d, orally) according to a random number table. Serum levels of some related biomarkers, including cholesterol synthesis markers (squalene, dihydrocholesterol, dehydrocholesterol, and lathosterol), and absorption markers (campesterol, stigmasterol, and sitosterol) as well as safety indices were obtained at baseline and after 8 weeks of the intervention. Results Eight weeks after treatment, both Xuezhikang and atorvastatin significantly reduced the levels of total cholesterol, triglycerides, low density cholesterol compared to baseline (all P<0.01). Xuezhikang significantly reduced the levels of squalene, dehydrocholesterol and lathosterol compared to baseline (all P<0.01), but atorvastatin only significantly reduced the level of squalene (P<0.01), compared to baseline. All cholesterol absorption markers showed no significant differences before and after treatment (P>0.05), however, a more obvious downward trend was shown in the Xuezhikang group. In addition, all the safety indices showed no significant differences between the two groups. Although the creatinekinase level in the Xuezhikang group was significantly higher, it remained within the safe range. Conclusions Xuezhikang may have more comprehensive effects on the markers of cholesterol synthesis and metabolism in early menopausal women with hypercholesterolemia through ergosterol and flavonoids in its "natural polypill."

三七作为我国传统中药,因其具有活血化瘀的功效,在治疗心血管疾病方面疗效显著,且随着现代中药提取技术的提高,三七提取物极大程度地提高了其作用功效.整理近几年国内外关于三七提取物(主要成分为三七总皂苷)在治疗心血管疾病(冠心病、高血压、心力衰竭、心律失常)时的作用机制、临床应用效果及可能的不良反应等文献,并对所查阅的相关文献进行相应的剖析、归纳及总结.本文结论为三七提取物三七总皂苷及其有效成分对治疗心血管疾病有明确疗效,尤其是在冠心病、高血压、心力衰竭、心律失常或多种疾病同时合并存在时,三七提取物三七总皂苷可起到使用单一药物而发挥多种药效的作用,同时减轻患者经济及精神压力,提高患者生活质量.

目的 了解近年来临床医学院本科生科研能力培养情况,为进一步开展本科生科研创新项目提供参考依据.方法 2020年5月对本院2015级临床医学本科生进行了问卷调查,共发放调查问卷38份,收回35份,回收率92.11％.结果 82.86％的学生在学习期间参与过科研课题工作,主要为临床应用、基础研究和调查研究;学生在科研工作的任务主要为查阅文献、收集数据和电脑录入.51.7％的学生认为参与课题研究收获很大和较大.62.1％的学生表示对导师满意和较满意;41.4％的学生认为导师对科研能力的培养重视和较重视;48.2％的学生认为导师对自己创新性的影响很大和较大.结论 通过与2009级临床医学本科生的调查结果进行对比研究,目前临床医学院本科生科研创新工作成效显著,但导师对学生科研能力培养的重视程度和创新性影响有待进一步提高.

我是一名从事医疗工作近40年的医务工作者,2020年新冠疫情发生后,我第一时间报名上前线.因为在17年前抗击"非典"时期,我曾带领百余名住院医师抗击疫情实现零感染. 这一次,在上级部门领导下,我带领社区卫生服务中心百余名医务人员坚守岗位,积极做好应急预案;建立"社区疫情防控办公室",亲自指挥部署各项防控工作;连续奋战70多天,每天超过12个小时,接收、传达各级政府部门的文件和指示;大年三十仍坚守在防控一线,这已经是第13个在工作中度过的除夕夜了……

目前综合型医学人才培养的关键是要加强对本科生科研能力的培养.为了解首都医科大学预防医学系本科阶段科研能力的培养情况,2020年5月对我院2017级预防医学专业学生进行了调查.此次调查共发放问卷48份,回收43份,回收率为89.6％.调查显示,79.1％的预防医学本科生在学习期间参与了医学课题研究的部分工作,主要任务依次是数据录入(50％)、收集数据(17.6％)和查阅文献(11.8％);认为参与科研工作收获较大的学生占53％,主要是通过文献查阅(29.4％)和参与讨论(29.4％).47％的学生认为导师对创新意识方面的影响很大和较大;61.8％的学生对导师的指导表示满意和较满意;38.3％的学生表示导师较重视科研能力的培养.通过调查,得出参与科研工作有利于了解科研课题的内容和部分方法、扩展学生的知识面,引导学生科研的思考能力,有利于学生下一阶段的学习.