Objective To study the effect of dietary nutrition intervention on blood rheology indexes of women with hypertension during pregnancy and the prevention effect of preeclampsia(PE).Methods A total of 120 women with hypertension during pregnancy were divided into a control group and an observation group according to random numerical table,with 60 cases in each group.The control group was given low-dose aspirin combined with labetalol intervention,and the observation group was combined with dietary nutrition intervention on the basis of the control group.Both groups were compared in terms of blood pressure[systolic blood pressure(SBP),diastolic blood pressure(DBP)],24-h urinary protein excretion and blood rheology indexes before and after intervention,gestational week of PE,gestational week of delivery,pregnancy outcome and neonatal outcome after intervention.Results After intervention,SBP,DBP and 24-h urinary protein excretion in both groups were significantly lower than those before intervention in this group;the observation group had SBP of(112.55±2.09)mm Hg(1 mm Hg= 0.133 kPa),DBP of(79.16±1.08)mm Hg,and 24-h urinary protein excretion of(1.01±0.25)g/24 h,which were significantly lower than those of(128.23±2.21)mm Hg,(87.86±1.32)mm Hg,and(2.23±0.43)g/24 h in the control group;the differences were statistically significant(P<0.05).After intervention,the whole-blood high-shear reduction viscosity,whole blood low-shear reduction viscosity,plasma viscosity,whole-blood high-viscosity and whole-blood low-shear reduction viscosity in both groups were significantly lower than those before intervention in this group;in the observation group,the whole-blood high-shear reduction viscosity was(7.16±0.96)mPa·s,the whole-blood low-shear reduction viscosity was(19.78±2.96)mPa·s,the plasma viscosity was(1.41±0.15)mPa·s,the whole-blood high-shear viscosity was(4.51±0.33)mPa·s,and the whole-blood low-shear viscosity was(8.97±1.22)mPa·s,which were lower than those of(7.72±1.02),(22.78±3.02),(1.63±0.23),(5.01±0.39),and(10.64±1.59)mPa·s in the control group;the differences were statistically significant(P<0.05).After intervention,the observation group had incidence of PE,preterm delivery,cesarean section,placental abruption,premature rupture of membranes,and postpartum hemorrhage were 28.3%,8.3%,25.0%,1.7%,3.3%and 3.3%,which were significantly lower than those of 55.0%,21.7%,61.7%,11.7%,13.3%and 20.0%in the control group;the gestational week of PE of(33.86±1.56)weeks and gestational week of delivery of(37.45±2.35)weeks in the observation group were significantly longer than those of(30.16±1.67)and(34.23±2.16)weeks in the control group;the differences were statistically significant(P<0.05).After intervention,the incidence of fetal distress and neonatal asphyxia were 3.3%and 1.7%in the observation group,which were significantly lower than those of 18.3%and 11.7%in the control group;the neonatal Apgar score of(8.53±1.24)points and neonatal weight of(2578.33±265.46)g in the observation group were significantly higher than those of(6.43±1.06)points and(2267.24±231.18)g in the control group;the differences were statistically significant(P<0.05).Conclusion Based on low-dose aspirin combined with labetalol intervention,dietary nutrition intervention can effectively control and stabilize blood pressure levels in women with hypertension during pregnancy,improve blood rheology indexes,prevent PE occurrence,and improve maternal and fetal outcomes.

目的 探讨宫腔镜电切术治疗子宫内膜息肉合并异常子宫出血的临床疗效,及其对患者围术期指标和炎症因子指标的影响,为临床提供参考.方法 选取2020年1月至2021年6月珠海市香洲区人民医院收治的82例子宫内膜息肉合并异常子宫出血患者作为研究对象,按照随机数字表法分为观察组和对照组,各41例.对照组患者接受刮宫术治疗,观察组患者接受宫腔镜电切术治疗.比较两组患者临床疗效、围术期相关指标及术后并发症、息肉复发情况,比较两组患者手术前后肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、白细胞介素-8(IL-8)水平.结果 观察组患者总有效率显著高于对照组(P<0.05);观察组患者手术时间、术中出血量、住院时间、月经恢复时间显著少于对照组(P<0.05);两组患者术后TNF-α、IL-6、IL-8水平显著高于术前,但观察组低于对照组(P<0.05);观察组患者术后并发症总发生率显著低于对照组(P<0.05);两组患者术后息肉复发率比较,差异无统计学意义(P>0.05).结论 与刮宫术比较,宫腔镜电切术治疗子宫内膜息肉合并异常子宫出血患者可获得更好的治疗效果,手术用时较短,创伤较轻,同时还能减少术后并发症发生率,值得在临床应用.