High-dimensional feature representations are widely used in machine learning-based cyberattack detection systems. However, they increase computational complexity and may hinder deployment in resource-constrained environments. In this paper, we investigate feature compression techniques for cyberattack classification by comparing two dimensionality reduction approaches: Principal Component Analysis (PCA) and Linear Predictive Coding (LPC). Compressed feature representations with varying dimensionalities are generated and evaluated across several classification models. Experimental analysis demonstrates that PCA preserves classification performance even under aggressive compression. On the other hand, LPC provides competitive predictive representations with slightly larger performance degradation. The results show that substantial reductions in feature dimensionality can be achieved with minimal impact on classification accuracy, highlighting the potential of lightweight feature compression for efficient cybersecurity analytics.

Medical Imagings are considered one of the crucial diagnostic tools for different bones-related diseases, especially bones fractures. This paper investigates the robustness of pre-trained deep learning models for classifying bone fractures in X-ray images and seeks to address global healthcare disparity through the lens of technology. Three deep learning models have been tested under varying simulated equipment quality conditions. ResNet50, VGG16 and EfficientNetv2 are the three pre-trained architectures which are compared. These models were used to perform bone fracture classification as images were progressively degraded using noise. This paper specifically empirically studies how the noise can affect the bone fractures detection and how the pre-trained models performance can be changes due to the noise that affect the quality of the X-ray images. This paper aims to help replicate real world challenges experienced by medical imaging technicians across the world. Thus, this paper establishes a methodological framework for assessing AI model degradation using transfer learning and controlled noise augmentation. The findings provide practical insight into how robust and generalizable different pre-trained deep learning powered computer vision models can be when used in different contexts.

Clinical biomarker workflows in translational research settings often rely on spreadsheet-driven tracking, manual quality control (QC) reconciliation, and loosely integrated systems, resulting in limited state visibility, delayed reporting, and increased operational risk. These challenges are particularly pronounced in multi-day assays such as Luminex-based quantification of Fragile X Messenger Ribonucleoprotein (FMRP), where HIPAA-compliant data governance, deterministic workflow progression, and coordinated communication across laboratory and clinical teams are required. This paper presents FMRP-LEAN, a HIPAA-compliant, AI-augmented Laboratory Information Management System (LIMS) architecture that formalizes biospecimen lifecycle management through a finite-state workflow model with explicit transition guards and dwell-time observability. The system integrates a self-hosted Supabase/PostgreSQL stack deployed within hospital-controlled infrastructure, hybrid edge-internal isolation with encrypted tunneling and loopback-only services, and bi-directional REDCap synchronization. A unified MRN-UUIDv7 identifier framework with QR-based tracking ensures traceable clinical-research linkage under PHI residency constraints. FMRP-LEAN incorporates automated statistical QC pre-screening and a governance-constrained AI operations module that operates exclusively on aggregate projections, with deterministic fallback guarantees. Deployment demonstrates improved workflow observability, reduced QC latency, and enhanced cross-role transparency between laboratory technicians, research coordinators, and patient-facing teams. The architecture provides a reproducible model for secure, state-explicit, and AI-augmented clinical research workflows in regulated healthcare environments.

Fragile X Syndrome (FXS) is a neurodevelopmental disorder caused by reduced expression of fragile X mental retardation protein (FMRP), leading to disrupted synaptic plasticity, cortical hyperexcitability, and impaired network synchronization. Electroencephalography (EEG) provides a noninvasive window into these mechanisms and consistently reveals abnormalities in alpha (8 to 12 Hz) and gamma (30 to 100 Hz) oscillations that relate to inhibitory control, sensory processing, and cognition. This paper proposes a multi representation deep learning framework for automated characterization of FXS EEG phenotypes by integrating convolutional neural networks (CNNs), long short-term memory (LSTM) networks, and recurrence plot (RP) analysis. Band limited EEG signals are decomposed into alpha and gamma components and transformed into complementary representations, including temporal feature sequences, time frequency maps, and RP images encoding the nonlinear recurrence structure. CNN modules learn discriminative spatial-spectral and dynamical textures from image based representations, while LSTM modules model temporal modulation of oscillatory activity; a hybrid CNN LSTM architecture jointly captures spatial, temporal, and nonlinear dependencies. Subject-independent evaluation demonstrates that the hybrid model outperforms single modality baselines, with gamma features providing strong discriminative power and alpha gamma integration yielding the best overall performance. These findings support deep learning with nonlinear representations as a scalable approach for EEG biomarker development in FXS, with potential utility for diagnosis, stratification, and treatment monitoring in translational settings.

Interpreting speech emotions and understanding emotion states has significantly increased interest in research to improve the quality of different services and advance human-computer interaction. Recurrent-based neural networks can be utilized to extract the spatial and temporal emotion patterns of speech. In this paper, we empirically evaluate different recurrent-based neural network capabilities for efficient and precise recognition of different emotion patterns in speech. Our empirical analysis and study focus on determining the optimal recurrent architecture for speech emotion recognition for real-time applications.

A seizure tracking system is crucial for monitoring and evaluating epilepsy treatments. Caretaker seizure diaries are used in epilepsy care today, but clinical seizure monitoring may miss seizures. Monitoring devices that can be worn may be better tolerated and more suitable for long-term ambulatory use. Many techniques and methods are proposed for seizure detection; However, simplicity and affordability are key concepts for daily use while preserving the accuracy of the detection. In this study, we propose a versal, affordable noninvasive based on a simple real-time k-Nearest-Neighbors (kNN) machine learning that can be customized and adapted to individual users in less than four seconds of training time; the system was verified and validated using 500 subjects, with seizure detection data sampled at 178 Hz, the operated with a mean accuracy of (94.5

Phishing attacks remain among the most prevalent cybersecurity threats, causing significant financial losses for individuals and organizations worldwide. This paper presents a machine learning-based phishing email detection system that analyzes email body content using natural language processing (NLP) techniques. Unlike existing approaches that primarily focus on URL analysis, our system classifies emails by extracting contextual features from the entire email content. We evaluated two classification models, Naive Bayes and Logistic Regression, trained on a combined corpus of 53,973 labeled emails from three distinct datasets. Our preprocessing pipeline incorporates lowercasing, tokenization, stop-word removal, and lemmatization, followed by Term Frequency-Inverse Document Frequency (TF-IDF) feature extraction with unigrams and bigrams. Experimental results demonstrate that Logistic Regression achieves 95.41

We introduce EEG Autoclean Vision Language AI (ICVision) a first-of-its-kind system that emulates expert-level EEG ICA component classification through AI-agent vision and natural language reasoning. Unlike conventional classifiers such as ICLabel, which rely on handcrafted features, ICVision directly interprets ICA dashboard visualizations topography, time series, power spectra, and ERP plots, using a multimodal large language model (GPT-4 Vision). This allows the AI to see and explain EEG components the way trained neurologists do, making it the first scientific implementation of AI-agent visual cognition in neurophysiology. ICVision classifies each component into one of six canonical categories (brain, eye, heart, muscle, channel noise, and other noise), returning both a confidence score and a human-like explanation. Evaluated on 3,168 ICA components from 124 EEG datasets, ICVision achieved k = 0.677 agreement with expert consensus, surpassing MNE ICLabel, while also preserving clinically relevant brain signals in ambiguous cases. Over 97

With the emergence of remote code execution (RCE) vulnerabilities in ubiquitous libraries and advanced social engineering techniques, threat actors have started conducting widespread fileless cryptojacking attacks. These attacks have become effective with stealthy techniques based on PowerShell-based exploitation in Windows OS environments. Even if attacks are detected and malicious scripts removed, processes may remain operational on victim endpoints, creating a significant challenge for detection mechanisms. In this paper, we conducted an experimental study with a collected dataset on detecting PowerShell-based fileless cryptojacking scripts. The results showed that Abstract Syntax Tree (AST)-based fine-tuned CodeBERT achieved a high recall rate, proving the importance of the use of AST integration and fine-tuned pre-trained models for programming language.

The Internet of Medical Things (IoMT) represents a paradigm shift in the healthcare sector, enabling the interconnection of medical devices, sensors, and systems to enhance patient monitoring, diagnosis, and management. The rapid evolution of IoMT presents significant benefits to the healthcare domains. However, there is a rapid increase in distributed denial of service (DDoS) attacks on the IoMT networks due to several vulnerabilities in the IoMT-connected devices, which negatively impact patients' health and can even lead to deaths. Thus, in this paper, we aim to save lives via investigating an extreme learning machine for detecting DDoS attacks on IoMT devices. The proposed approach achieves a high accuracy at a low implementation budget. Thus, it can reduce the implementation cost of the DDoS detection system, making the model capable of executing on the fog level.

The rapid integration of the Internet of Things (IoT) and Internet of Medical (IoM) devices in the healthcare industry has markedly improved patient care and hospital operations but has concurrently brought substantial risks. Distributed Denial-of-Service (DDoS) attacks present significant dangers, jeopardizing operational stability and patient safety. This study introduces CryptoDNA, an innovative machine learning detection framework influenced by cryptojacking detection methods, designed to identify and alleviate DDoS attacks in healthcare IoT settings. The proposed approach relies on behavioral analytics, including atypical resource usage and network activity patterns. Key features derived from cryptojacking-inspired methodologies include entropy-based analysis of traffic, time-series monitoring of device performance, and dynamic anomaly detection. A lightweight architecture ensures inter-compatibility with resource-constrained IoT devices while maintaining high detection accuracy. The proposed architecture and model were tested in real-world and synthetic datasets to demonstrate the model's superior performance, achieving over 96 accuracy with minimal computational overhead. Comparative analysis reveals its resilience against emerging attack vectors and scalability across diverse device ecosystems. By bridging principles from cryptojacking and DDoS detection, CryptoDNA offers a robust, innovative solution to fortify the healthcare IoT landscape against evolving cyber threats and highlights the potential of interdisciplinary approaches in adaptive cybersecurity defense mechanisms for critical healthcare infrastructures.

As computing power advances, the environmental cost of semiconductor manufacturing and operation has become a critical concern. However, current sustainability metrics fail to quantify carbon emissions at the transistor level, the fundamental building block of modern processors. This paper introduces a Carbon Per Transistor (CPT) formula, a novel approach and green implementation metric to measuring the CO_2 footprint of semiconductor chips from fabrication to end-of-life. By integrating emissions from silicon crystal growth, wafer production, chip manufacturing, and operational power dissipation, the CPT formula provides a scientifically rigorous benchmark for evaluating the sustainability of computing hardware. Using real-world data from Intel Core i9-13900K, AMD Ryzen 9 7950X, and Apple M1/M2/M3 processors, we reveal a startling insight—manufacturing emissions dominate, contributing 60–125 kg CO_2 per CPU, far exceeding operational emissions over a typical device lifespan. Notably, Apple’s high-transistor-count M-series chips, despite their energy efficiency, exhibit a significantly larger carbon footprint than traditional processors due to extensive fabrication impact. This research establishes a critical reference point for green computing initiatives, enabling industry leaders and researchers to make data-driven decisions in reducing semiconductor-related emissions and get correct estimates for the green factor of the information technology process. The proposed formula paves the way for carbon-aware chip design, regulatory standards, and future innovations in sustainable computing.

Today’s world sees an explosion of Internet of Things devices, including so many that are marketed to the general public and used by consumers within their homes. Their uptake is growing and becoming more and more a part of daily life even though such devices can and do often provide data that in turn reveals much of what people may want to keep private inside their homes and offices. In turn, this poses major questions in terms of cybersecurity: how secure are these devices, what are these devices seeing (and saying), and how can they be compromised?

The denial of service (DoS) and distributed denial of service (DDoS) attacks are considered the most frequent attacks targeting the Internet of Things (IoT) network infrastructure globally. The current approaches for detecting DoS and DDoS attacks mainly use intrusion detection systems, traffic monitoring, and firewalls. However, complex DoS and DDoS attacks can bypass these detection mechanisms. Thus, this paper proposes utilizing convolutional neural network-based transfer learning to detect DoS and DDoS attacks from converted network traffic data into images. We employed the Xception model with fine-tuning, and we achieved an average of 91% accuracy in detecting eleven different types of DoS and DDoS attacks, which is higher than the current state-of-the-art by 5% targeting the same task.

Integrating Internet of Things (IoT) devices in healthcare has revolutionized patient care, offering improved monitoring, diagnostics, and treatment. However, the proliferation of these devices has also introduced significant cybersecurity challenges. This paper reviews the current landscape of cybersecurity threats targeting IoT devices in healthcare, discusses the underlying issues contributing to these vulnerabilities, and explores potential solutions. Additionally, this study offers solutions and suggestions for researchers, agencies, and security specialists to overcome these IoT in healthcare cybersecurity vulnerabilities. A comprehensive literature survey highlights the nature and frequency of cyber attacks, their impact on healthcare systems, and emerging strategies to mitigate these risks.

Healthcare AI systems have historically faced challenges in merging contextual reasoning, long-term state management, and human-verifiable workflows into a cohesive framework. This paper introduces a completely innovative architecture and concept: combining the Model Context Protocol (MCP) with a specific clinical application, known as MCP-AI. This integration allows intelligent agents to reason over extended periods, collaborate securely, and adhere to authentic clinical logic, representing a significant shift away from traditional Clinical Decision Support Systems (CDSS) and prompt-based Large Language Models (LLMs). As healthcare systems become more complex, the need for autonomous, context-aware clinical reasoning frameworks has become urgent. We present MCP-AI, a novel architecture for explainable medical decision-making built upon the Model Context Protocol (MCP) a modular, executable specification for orchestrating generative and descriptive AI agents in real-time workflows. Each MCP file captures clinical objectives, patient context, reasoning state, and task logic, forming a reusable and auditable memory object. Unlike conventional CDSS or stateless prompt-based AI systems, MCP-AI supports adaptive, longitudinal, and collaborative reasoning across care settings. MCP-AI is validated through two use cases: (1) diagnostic modeling of Fragile X Syndrome with comorbid depression, and (2) remote coordination for Type 2 Diabetes and hypertension. In either scenario, the protocol facilitates physician-in-the-loop validation, streamlines clinical processes, and guarantees secure transitions of AI responsibilities between healthcare providers. The system connects with HL7/FHIR interfaces and adheres to regulatory standards, such as HIPAA and FDA SaMD guidelines. MCP-AI provides a scalable basis for interpretable, composable, and safety-oriented AI within upcoming clinical environments.

By 2050, it is predicted that there will be 9 billion people on the planet, which will call for more production, lower costs, and the preservation of natural resources. It is anticipated that atypical occurrences and climate change will pose severe risks to agricultural output. It follows that a 70% or more significant rise in food output is anticipated. Smart farming, often known as agriculture 4.0, is a tech-driven revolution in agriculture with the goal of raising industry production and efficiency. Four primary trends are responsible for it: food waste, climate change, population shifts, and resource scarcity. The agriculture industry is changing as a result of the adoption of emerging technologies. Using cutting-edge technology like IoT, AI, and other sensors, smart farming transforms traditional production methods and international agricultural policies. The objective is to establish a value chain that is optimized to facilitate enhanced monitoring and decreased labor expenses. The agricultural sector has seen tremendous transformation as a result of the fourth industrial revolution, which has combined traditional farming methods with cutting-edge technology to increase productivity, sustainability, and efficiency. To effectively utilize the potential of technology gadgets in the agriculture sector, collaboration between governments, private sector entities, and other stakeholders is necessary. This paper covers Agriculture 4.0, looks at its possible benefits and drawbacks of the implementation methodologies, compatibility, reliability, and investigates the several digital tools that are being utilized to change the agriculture industry and how to mitigate the challenges.

Fileless malware predominantly relies on PowerShell scripts, leveraging the native capabilities of Windows systems to execute stealthy attacks that leave no traces on the victim's system. The effectiveness of the fileless method lies in its ability to remain operational on victim endpoints through memory execution, even if the attacks are detected, and the original malicious scripts are removed. Threat actors have increasingly utilized this technique, particularly since 2017, to conduct cryptojacking attacks. With the emergence of new Remote Code Execution (RCE) vulnerabilities in ubiquitous libraries, widespread cryptocurrency mining attacks have become prevalent, often employing fileless techniques. This paper provides a comprehensive analysis of PowerShell scripts of fileless cryptojacking, dissecting the common malicious patterns based on the MITRE ATT&CK framework.

The electroencephalogram (EEG) is a valuable and widely applied tool for investigating brain disorders and behavioral changes. It offers a minimally restrictive and non-invasive method. However, challenges in using EEG for cognitive development studies include temporal resolution, signal source localization, and EEG artifacts. Careful consideration of these factors is essential for informed application of EEG technology. Independent component analysis (ICA) effectively isolates source generator processes from signals recorded by multiple, adjacent EEG scalp electrodes. Although ICA decomposition requires manual inspection, selection, and interpretation of independent components (ICs), this process is time-consuming and demands expertise. Automated IC classification can achieve sufficient accuracy, expediting large-scale EEG research and enabling near-real-time applications in conjunction with brain activity rejection tasks, which are crucial for medical specialists. This study introduces an automated computer vision-based ICA rejection labeling tool compatible with widely used software interfaces like ICLabel and EEGLab. By automating the manual task, the proposed system reduces processing time by 7200-fold and achieves an accuracy of 89.45