Arumugam Pillai Seethai Ammal College, is a general degree college located in Tiruppattur, Sivaganga district, Tamil Nadu. It was established in the year 1965. The college is affiliated with Alagappa University. This college offers different courses in arts, commerce and science..
In this work, a trisphenol (TR) was synthesized using hydroxybenzaldehyde and phenol under appropriate experimental conditions. Tri-functional benzoxazines were synthesised utilizing trisphenol (TR) with four different amines, 2-allylamine (aa), furan-2-ylmethanamine (ffa), cyclohexanamine (cha) and adamantan-1-amine (ada) in the presence of paraformaldehyde through Mannich condensation. The TR based furan-2-ylmethanamine polybenzoxazine was chosen for the preparation of composites using bio-calcium silicate (CS) obtained from bio wastes such as egg-shell powder (bio-calcium) and rice husk ash (bio-silica). It was observed that the lowest value of dielectric constant was obtained for 15wt
This study focused to compare the synthesis, characterization and antibacterial, and antioxidant efficacy of chitosan-mediated silver (Ag) and cerium oxide (CeO2) nanoparticles (NPs) from marine biowaste of Portunus sanguinolentus. The Ag and CeO2 NPs were synthesized and preliminarily characterized by microscopic and spectroscopic techniques, which revealed chitosan-assisted Ag and CeO2 NPs were mostly spherical and irregular in form, respectively. Findings of the NPs for their effectiveness in combating bacteria: chitosan-assisted Ag and CeO2 NPs exhibited excellent activity against Bacillus subtilis (23.3 +/- 0.28 and 15.2 +/- 0.19 mm) followed by Klebsiella pneumoniae (20.3 +/- 0.11 and 18.5 +/- 0.28 mm), respectively. The findings of in vitro antioxidant activity revealed that chitosan-mediated NPs possess significant reducing power and hydroxyl radical scavenging properties; the concentration was raised to 125 & micro;g/mL, and the scavenging capacity of Ag NPs improved drastically to 63.8% and 58.7%, for CeO2 NPs. The findings of chitosan-mediated Ag and CeO2 NPs derived using crab's shell waste reveal that they possess a potential effect on bacterial infections and free radicals.
A bi-phase electrochemical method for the selective oxidation of piperonol to piperonaldehyde has been developed using an undivided cell equipped with carbon (C) and stainless steel (SS) electrodes. The reaction proceeds in an aqueous NaNO3 electrolyte with a catalytic amount of H2SO4 under mild conditions, affording piperonaldehyde in 78
Direct pyrolysis of SnO2 nanoparticles mixed with bisphenol-BA/aniline polybenzoxazine yields highly graphitized, Sn metal doped porous carbon material (Sn–C). The prepared Sn–C was used as a reinforcement for the development of composites with bisphenol-BA and furfuryl amine based polybenzoxazine (poly(BBA-ffa)). The maximum degradation temperature of the Sn–C reinforced poly(BBA-ffa) composites reached to 526 °C with 65
Earthworms, known for their role in the ecosystem as agents of soil fertility and nutrient cycling, are increasingly being sought after in biomedical research. Current research has revealed a plethora of biologically active compounds present in earthworm tissues, coelomic fluid, and resident microbiota that present promising leads towards the therapeutic treatment of several cancer types. This review provides an extensive overview of existing knowledge on biomolecules from earthworms, focusing their therapeutic value in the management of lung cancer. Some key bioactives, lumbrokinase (a serine protease isolated from Lumbricus rubellus) display fibrinolytic and anticancer activities through modulation of apoptosis-related proteins (e.g., caspase-3, Bax, Bcl-2) and inhibition of PI3K/Akt and NF-κB signaling pathways. Other significant compounds include earthworm glycoproteins, which induce innate immune response, and lectins that inhibit EGFR signaling in lung cancer cells. Dendrobaena veneta coelomic fluid is a rich source of Venetin-1, a protein-polysaccharide complex that selectively induces apoptosis in lung cancer cells. Further, earthworm metalloproteinases are capable of inhibiting tumor invasion by degrading extracellular matrix. Sophisticated extraction and analytical methods including chromatography, mass spectrometry, and spectroscopy have made it possible to characterize such complex molecules precisely. These biomolecules are still in their infancy when it comes to clinical translation, despite the strong findings. For pharmacokinetics, bioavailability, and safety to be established, more preclinical and clinical studies are required. Through further investigation, earthworms could prove useful partners in the search for novel and natural anti-cancer drugs.
