University Center of Brasília

This study aimed to evaluate whether the quality of injection and number of oocytes injected during Intrafollicular Transfer of Immature Oocytes (IFIOT) affect ovulation timing, follicle dynamics, oocyte recovery, nuclear maturation and in vitro embryo production in beef heifers. In three experiments, ovulator cows were synchronised and subjected to IFIOT, followed by the evaluation of follicular regression, recovery of cumulus-oocyte complexes (COCs), oocyte nuclear maturation, embryo development and pregnancy outcomes after embryo transfer. Data were analysed using the chi-square test and Proc Glimmix (SAS Institute). The injection procedure did not affect ovulation timing but induced follicular regression (p < 0.05). Injection quality and number of oocytes injected affected COC recovery (p < 0.05), with higher recovery rates observed following good-quality injections and lower oocyte numbers (48.90% vs. 24.49%). Although nuclear maturation rates and embryo production were similar (p > 0.05) across the groups, embryos produced via IFIOT exhibited a higher (p < 0.05) proportion of blastocysts classified as suitable for cryopreservation (51.72% vs. 33.81%). Furthermore, after transfer, the pregnancy rates of cryopreserved IFIOT-derived blastocysts were comparable to those of embryos produced using conventional in vitro maturation. These findings indicate that although IFIOT did not increase the total embryo yield, it improved oocyte recovery and significantly enhanced the production of high-quality cryotolerant blastocysts. Therefore, improving the injection technique is critical for enhancing IFIOT efficiency and embryo developmental competence.

Introduction: Recent medical undergraduate curricula have integrated technology, such as virtual reality simulators (VRS), enabling ongoing clinical skills training, including the objective structured clinical examination (OSCE), semiology, and professional tools [...]

Introduction: Anaplastic Thyroid Carcinoma (ATC) is a rare and highly lethal neoplasm [...]

This study aims to analyze the relationship between human resource (HR) practices and Quality of Work Life (QWL) among IT professionals, considering two distinct bundles of HR practices: performance-oriented and employee-support-oriented. In the last few decades, there have been professionals’ practices oriented toward performance and well-being that are essential in balancing demands and resources in how employees experience the QWL. Mixed methods were used to analyze perceived HR practices and QWL among 302 Brazilian IT professionals. Results show that a balanced and richer HR system enhances QWL. Moreover, specific bundles of HR practices have stronger effects in specific dimensions of QWL. The mixed-methods approach provides insights into the asymmetric U-shaped pattern between HR practices and QWL. The present research contributes to enhancing the Quality of Work Life research in HR management and provides evidence of different bundles of HR practices.

O presente artigo analisa a evolução do reconhecimento dos ani- mais não humanos como sujeitos de direitos e seus impactos na responsa- bilidade profissional do médico-veterinário. Parte-se da senciência como fundamento biológico, ético e jurídico, destacando sua consolidação cien- tífica e sua incorporação progressiva no ordenamento jurídico brasileiro, especialmente a partir da vedação constitucional à crueldade. A partir des- se marco, discute-se a emergência da dignidade animal e a consolidação do Direito Animal como ramo jurídico autônomo, voltado à proteção do animal individual. Nesse contexto, examina-se a reconfiguração da atuação médico-veterinária, que passa a transcender a relação contratual com o responsável, assumindo a tutela direta dos interesses do paciente-animal. Por fim, são abordados os fundamentos da responsabilização profissional, incluindo a tríade clássica da culpa e a incorporação do conceito de violência médico-veterinária, ampliando os critérios ético-jurídicos de avaliação da conduta profissional.