
目的:探讨团队式授权教育对肾移植术患者自我效能、健康行为水平及认知态度的影响。方法:选取郑州市第七人民医院洁净手术部2018年1月至2021年1月期间收治的83例肾移植术患者作为研究对象,采用数字表法随机分为两组。对照组41例给予肾移植术相关知识、免疫抑制剂用药管理、并发症预防、随访等常规干预及健康教育,观察组42例给予联合团队式授权教育。比较两组患者自我效能、健康行为、认知态度。结果:干预后,观察组症状自我管理、疾病共性管理、治疗行为、社会心理行为、饮食行为、躯体活动行为、态度、认知状态、行为状态评分均高于对照组,差异具有统计学意义( P<0.05)。 结论:团队式授权教育对肾移植术患者效果确切,能够有效改善患者认知态度,提高自我效能,养成健康行为,具有临床推广价值。
Objective:To explore the effect of accurate extension management based on network interactive platform in malignant lymphoma (ML) patients with peripherally inserted central catheters(PICC).Methods:A total of 111 ML patients with PICC catheterization from October 2020 to October 2021 were selected and divided into groups according to the lottery method. The patients of the control group (55 cases) received precision nursing strategy intervention, and the patients of the observation group (56 cases) combined with extended nursing services based on the network interactive platform on the basis of the control group. The safety index, self-management ability, health behavior and incidence of unplanned extubation were compared between the two groups.Results:There was no statistical significance in catheter indwelling time, symptomatic PICC-UED-VT, phlebitis, catheter-related bloodstream infection and the incidence of unplanned extubation in two groups ( P>0.05). After the intervention, the health-promoting lifestyle scale, self-efficacy, self-management scale and self-care agency scale scores in the observation group were higher than those in the control group ( P<0.05). Conclusions:The accurate extended management based on the network interactive platform can effectively prevent the occurrence of complications such as infection and catheter-related thrombosis in patients with ML catheterization through PICC, and improve health behavior and self-management ability.
Objective:To explore the effects of acceptance and commitment therapy on stigma, disability acceptance and post-traumatic growth in patients with lower limb amputations.Methods:A total of 116 patients with lower limb amputation in Department of Burn Microsurgery, the First Affiliated Hospital of Henan University of Science and Technology from October 2020 to October 2022 were selected as the study subjects and divided into nursing group and treatment group according to the intervention method. Fifty-eight patients in the nursing group were given routine nursing intervention, and 58 patients in the therapy group were given acceptance and commitment therapy intervention. The stigma, disability acceptance and post-traumatic growth between the two groups were compared.Results:Six months after intervention, the scores of economic discrimination, social exclusion, social isolation and intrinsic shame in both groups were lower than those before intervention, and those patients in the treatment group were lower than those in the nursing group ( P<0.05). Six months after intervention, the value range of the two groups was increased, and the change scores from relative value to intrinsic value were higher than before intervention, and the treatment group was higher than the nursing group ( P<0.05). Six months after intervention, the scores of life perception, personal strength, new possibilities and relationship with others in both groups were higher than those before intervention, and those patients in the treatment group were higher than those in the nursing group ( P<0.05). Conclusion:Acceptance and commitment therapy can increase disability acceptance, improve stigma and enhance post-traumatic growth in patients with lower limb amputations.
Objective:To investigate the effects of early quantification of lung rehabilitation training on cardiopulmonary function rehabilitation, inflammatory factor levels and exercise ability of patients after lung transplantation.Methods:A total of 80 lung transplanted patients admitted to the First Affiliated Hospital of Zhengzhou University from August 2020 to November 2022 were enrolled in this study, and divided into two groups according to the computer grouping method. Forty patients in the traditional group was given routine lung rehabilitation training, while 40 patients in the optimized group was given early quantitative lung rehabilitation training. The levels of cardiopulmonary function, exercise ability and inflammatory factors were compared between the two groups.Results:The forced expiratory volume in one second (FEV1), forced vital capacity (FVC), FEV1/FVC, and maximal inspiratory pressure (MIP) in the optimized group were higher than those in the traditional group ( P<0.05). The 6-minute walking distance (6MWD) of the optimized group was longer than that of the traditional group, and the DE Morton mobility index (DEMMI) score was higher than that of the traditional group ( P<0.05). The plateletocrit (PCT), C-reactive protein (CRP) and white blood cells (WBCs) of the optimized group were lower than those of the traditional group ( P<0.05). Conclusion:Early quantified lung rehabilitation therapy after lung transplantation is beneficial to enhance the cardiopulmonary function, improve the exercise ability and improve the inflammation index.
Objective:To explore the effect of microdynamic negative pressure technique on diabetic foot ulcer patients and its effect on wound healing and reducing bacterial infection.Methods:A total of 98 patients with diabetic foot ulcer from November 2020 to November 2022 in Wound Center of Yellow River Central Hospital were selected and grouped according to random number table method.Both groups were treated with antibiotics, 49 cases in the control group were treated with foam plastic dressing, and 49 cases in the observation group were treated with microdynamic negative pressure technology intervention.Two weeks later, the healing situation of ulcer surface in the two groups including wound healing rate, complete healing time of ulcer, dressing change times, and 1-month follow-up ulcer recurrence rate was compared.The effusion indexes of ulcer surface including vascular endothelial growth factor (VEGF), matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase tissue inhibitor-1 (TIMP-1) were further compared.Positive bacterial culture of wound surface and incidence of adverse reactions between two groups were also compared.Results:After 1 month of follow-up, the wound healing rate, ulcer recurrence rate and incidence of adverse reactions were not statistically significant between the two groups ( P>0.05).After intervention, the ulcer complete healing time, dressing change times, bacterial culture positive rate and MMP-2 level in the observation group were significantly lower than those in the control group, while the VEGF and TIMP-1 levels in the observation group were significantly higher than those in the control group ( P<0.05). Conclusion:Compared with foam plastic dressings, microdynamic negative pressure technique can effectively regulate the level of growth factor in effusion, reduce the positive rate of bacteria, and promote rapid wound healing with high safety in patients with diabetic foot ulcer.
Objective:To investigate the effect of cement augmented pedicle screw instrumentation (CAPSI) on osteoporotic vertebral compression fracture (OVCF) and its effects on serum bone metabolism and inflammation.Methods:A total of 132 patients with OVCF in our hospital from February 2020 to February 2023 were randomly divided into group A ( n=66) and group B ( n=66). Group B received pedicle screw internal fixation (PPSF) and group A received CAPSI. Perioperative indexes, anatomical parameters of injured vertebrae(sagittal Cobb Angle, anterior vertebral margin height ratio (AVH))before and after the surgery, surgical effect, bone metabolism(total parathyroid hormone (iPTH), osteocalcin (OC), β-CTX)levels, inflammatory factors(interleukin-1 (IL-1), IL-6, tumor necrosis factor-α (TNF-α))levels were compared between the two groups. Results:The time of turning over, hospitalization and getting out of bed in group A were shorter than that in group B, and the time of operation was longer than that in group B ( P<0.05). The sagittal Cobb Angle in group A was lower, and the AVH in group B was higher than that in group B 3 months after the operation ( P<0.05). The excellent and good rate of operation in group A was (96.97% (64/66)) higher than that in group B (84.85% (56/66)) ( P<0.05). Serum β-CTX and iPTH levels in group A were lower than those in group B, and serum OC level was higher than those in group B 3 months after the surgery ( P<0.05). Serum levels of IL-1, IL-6 and TNF-α in group A were lower than those in group B 3 months after the operation ( P<0.05). Conclusion:Compared with PPSF in OVCF patients, CAPSI treatment can be more conducive to improving the surgical effect, optimizing perioperative indexes, alleviating the inflammatory response of the body, promoting the recovery of the anatomical structure of the injured vertebra, improving the level of bone metabolism, and has positive significance in promoting fracture healing, but it would slightly prolong the operation time.
Objective:To investigate the effects of SuperPATH minimally invasive primary total hip replacement in patients with alcoholic osteonecrosis of the femeral head (ONFH).Methods:A total of 126 patients with ONFH in our department from May 2019 to January 2022 were assigned to the control group (63 cases) who underwent posterolateral small incision for hip replacement, and the observation group (63 cases) who received SuperPATH minimally invasive approach for total hip replacement. Perioperative outcome index, pain degree, hip function and complication rate of the two groups were observed.Results:There was no statistical significance in the incision length between the two groups ( t=1.78, P=0.079. The intraoperative blood loss in the observation group was less than those in the control group( t=8.70, P<0.001), and the operation time( t=8.92, P<0.001) and hospital stay( t=8.57, P<0.001) were shorter than those in the control group. The differences in the circumference of the thighs( t=8.60, P<0.001) and the length of the lower limbs( t=23.59, P< 0.001) were less than those in the control group. After 6 months’ treatment, visual analogue scale scores of observation group was lower than that of control group ( t=14.160, P<0.001). Hip Harris function score in the observation group was higher than that in the control group at 3 months( t=2.39, P=0.019), 6 months( t=7.78, P<0.001) and 12 months( t=9.80, P<0.001) after surgery. There was no statistical significance in postoperative complications between the two groups( χ2=1.87, P= 0.171). Conclusion:Primary SuperPATH minimally invasive approach for total hip replacement in patients with alcoholic ONFH can effectively reduce trauma, accelerate recovery, relieve pain, improve hip function, and reduce postoperative complications.
目的:探究2型糖尿病周围神经病变患者运用步行阶梯训练的效果。方法:选取黄河水利委员会黄河中心医院收治的116例2型糖尿病周围神经病变患者,根据数字表法随机分组。对照组58例给予常规有氧运动训练,观察组58例增加步行阶梯训练,两组均持续干预6个月,对比疗效。结果:干预后,观察组足底压力中心轨迹(COP)曲线异常率、全足压力变化曲线异常率、全足平衡性曲线异常率、计时-起立测试(TUGT)、跌倒指数(FI)低于对照组,差异具有统计学意义( P<0.05)。干预后,观察组睁眼单腿站立测试(OLST)、闭眼OLST均高于对照组,差异具有统计学意义( P<0.05)。 结论:有氧运动与步行阶梯训练改善神经传导速度效果相当,但步行阶梯训练联合有氧运动改善2型糖尿病周围神经病变患者的动态平衡功能、步态调控效果更佳。
Objective:To evaluate the predictive value of serum potassium level for abdominal aortic calcification (AAC) in non-dialysis patients with type 2 diabetes mellitus (T2DM) end-stage renal disease(ESRD).Methods:A total of 137 T2DM patients with ESRD non-dialysis in the Second People’s Hospital of Jiyuan from January 2021 to January 2023 were collected. AAC was assessed by lateral abdominal plain radiographs. According to the presence of AAC, the patients were divided into two groups. Basic data were recorded and compared. The related factors of AAC and different AAC grades in T2DM patients with ESRD without dialysis were analyzed by binary logistic regression.The predictive value of related factors for AAC risk was analyzed by the receiver operating characteristic curve(ROC).Results:There were significant differences in diastolic blood pressure, age, parathyroid hormone, alkaline phosphatase, blood potassium and cardiovascular and cerebrovascular disease between AAC group and non-AAC group ( P<0.05). There were no significant differences in gender, systolic blood pressure, body mass index (BMI) and 25-hydroxyvitamin D 3 between the two groups ( P>0.05). The blood potassium and age were correlated with AAC ( P<0.05), and blood potassium was correlated with the severity of AAC in T2DM patients without dialysis ( P<0.05).ROC analysis showed that the area under the curve (AUC) was 0.780, the confidence interval was 0.705-0.855, the cut-off value was 4.745mmol/L, the sensitivity was 57.0%, and the specificity was 74.1% ( P<0.05) for the diagnosis of AAC in type 2 diabetic patients with ESRD without dialysis( P<0.05).Serum potassium was used to diagnose T2DM non-dialysis patients with ESRD with AAC score>5. The area under the curve was 0.855, the confidence interval was 0.730-0.980, the critical value was 4.265 mmol/L, the sensitivity was 89.2%, and the specificity was 78.6% ( P<0.05). Conclusion:Blood potassium and age were risk factors for AAC in T2DM patients with non-dialysis ESRD. Blood potassium had predictive value for AAC, and the sensitivity and specificity were high for obvious calcification with AAC>5.
目的:探讨连续性护理在角膜移植术后患者中的作用。方法:选取济南市第二人民医院眼科研究所2018年10月至2020年10月诊治的84例接受角膜移植术的眼角膜病患者作为研究对象,按照抽签法分为对照组和观察组。对照组42例予以常规护理,观察组42例予以常规护理与连续性护理合用,对比两组患者认知水平、并发症和视觉功能。结果:观察组认知水平得分更高,出现并发症的几率更低,两项指标组间对比差异有统计学意义( P<0.05);患者护理前视觉功能对比差异无统计学意义( P>0.05),两组患者经护理后,视觉功能评分均明显高于护理前,且观察组高于对照组( P<0.05)。 结论:在角膜移植术后应用连续性护理可提高患者认知水平,减少术后并发症少,对视觉功能改善作用明显。
目的:探讨精准营养疗法联合腹直肌锻炼操应用于结直肠癌合并2型糖尿病患者的效果。方法:选取2022年1月至2023年3月濮阳市中医医院收治的120例结直肠癌合并2型糖尿病患者作为研究对象,按照数字表法随机分入研究组( n=60)和对照组( n=60)。对照组患者采用常规营养支持联合腹直肌锻炼操,研究组患者采用精准营养疗法联合腹直肌锻炼操。比较两组患者营养状态、应激反应以及不良反应发生情况。 结果:术后7 d两组转铁蛋白(TF)、血清总蛋白(ALB)、血红蛋白(Hb)、前清蛋白(PA)、体重(BW)、上臂肌围(AMC)均低于术前,且研究组高于对照组(均 P<0.05)。术后7 d两组补体3(C3)、补体4(C4) 、C反应蛋白(CRP)水平均高于术前,且研究组低于对照组( P值均<0.05)。研究组不良反应发生率(20.00%)低于对照组(38.33%)( P<0.05)。 结论:结直肠癌合并2型糖尿病患者采取精准营养疗法联合腹直肌锻炼操相结合可有效改善患者的营养状况,缓解应激反应,降低术后不良反应风险。
Objective:To investigate the effects of insulin Degludec/Aspart on glucose metabolism, islet function and oxidative stress in patients with early diabetic nephropathy.Methods:A total of 102 patients with early diabetic nephropathy in Department of Endocrinology of Ruzhou First People’s Hospital from January 2021 to November 2022 were enrolled as research subjects and divided by coin toss method. Fifty-one patients in the control group received conventional treatment, and 51 patients in the study group received insulin Degludec/Aspart therapy. Glucose metabolism indexes, islet function indexes, oxidative stress state and adverse reactions were compared between the two groups.Results:The levels of fasting blood glucose( t=4.32, P<0.001), 2-h postprandial blood glucose( t=5.30, P<0.001)and glycosylated hemoglobin( t=4.83, P<0.001) in the study group were lower than those in the control group. The insulin resistance index of the study group was higher than that of the study group( t=4.33, P<0.001), the islet β cell function index( t=4.85, P<0.001) and fasting insulin level( t=4.88, P<0.001) were lower than those of the basic group. The levels of glutathione peroxidase( t=4.60, P<0.001) and superoxide dismutase( t=4.74, P<0.001) in the study group were higher than those in the basic group, and the level of malondialdehyde was lower than that in basic group( t=4.96, P<0.001). There was no significant difference between the two groups in incidence of gastrointestinal reaction( χ2=0.44, P=0.505), fatigue( χ2<0.01, P=1.000) or dizziness( χ2=0.14, P=0.713). Conclusion:Insulin Degludec/Aspart can effectively reduce blood glucose level, improve islet function and reduce oxidative stress in patients with early diabetic nephropathy, with high safety.
Objective:To investigate the effects of low-phosphorus diet on calcium, phosphorus metabolism, skin itching and nutritional status in maintenance hemodialysis patients.Methods:A total of 87 patients with maintenance hemodialysis admitted to the Department of Blood Purification of the First Affiliated Hospital of Henan University of Science and Technology from August 2021 to August 2022 were enrolled. It was divided into two groups by lottery, with 43 patients in the control group receiving a conventional diet and 44 patients in the observation group being given a low-phosphorus diet. The two groups were compared with the blood phosphorus and calcium levels, the scores of the Four Item Itch Questionnaire (FIIQ), serum albumin and prealbumin levels before and after the intervention.Results:The blood phosphorus in the post-intervention observation group was lower than that in the control group ( t=10.94, P<0.001), and the distribution of itching in the FIIQ score ( t=12.70, P<0.001), severity ( t=8.29, P<0.001), frequency ( t=21.85, P<0.001), and effect on sleep ( t=11.87, P<0.001) were lower than those in the control group, and the serum calcium ( t=3.07, P=0.003), albumin ( t=5.13, P<0.001), and prealbumin ( t=4.46, P< 0.001) were higher than that of the control group, and the difference was statistically significant ( P< 0.05). Conclusion:Low-phosphorus diet can effectively reduce the degree of skin itching, calcium and phosphorus metabolism and nutritional status of maintenance hemodialysis patients.
Objective:To investigate the impacts of epalrestat in combination with alprostel on serum oxidative stress indices and fundus microcirculation in patients with early diabetic retinopathy (DR).Methods:A total of 123 individuals with early DR were chosen and categorized using the random number table approach in the Ophthalmology Department of Hebi People’s Hospital. Epalrestat was administered in combination with pancreatic kininogenase to 61 patients in the control group and alprodyl injection to 62 patients in the observation group. The indices of fundus microcirculation, serum oxidative stress, inflammatory factor levels, and adverse responses were evaluated.Results:Following treatment, the number of microhemangiomas( t=17.61, P<0.001), the area of hemorrhage( t=16.63, P<0.001) and the area of exudation( t=31.49, P<0.001) were fewer than those in the control group. Malondialdehyde( t=7.81, P<0.001), tumor necrosis factor-α( t=15.23, P<0.001) and interleukin-2( t=7.94, P<0.001) were lower than those in the control group, while the observation group’s levels of superoxide dismutase( t=7.15, P<0.001), total antioxidant capacity( t=5.81, P<0.001) and interleukin-10 ( t=6.27, P<0.001)were higher than those in the control group. The incidence of adverse responses was not significantly different between the two groups ( P>0.05). Conclusion:The use of ipalrestat and alproprol together can significantly enhance fundus microcirculation, lower oxidative stress, and reduce inflammation while posing little risks to individuals with early DR.
目的:探讨认知行为模式结合膳食干预对血液透析患者的应用价值。方法:选取2020年2月至2021年8月烟台市烟台山医院急诊科接收的88例尿毒症血液透析患者作为研究对象,通过数字表法将研究对象随机分为参照组和观察组,每组各44例。参照组和观察组分别采用常规护理干预和认知行为模式结合膳食干预,比较两组患者营养状态、免疫功能、生活质量。结果:观察组患者体质指数为(22.24±2.26)kg/m 2,白蛋白为(33.35±2.35)g/L,血清前白蛋白为(254.48±4.42)mg/L,CD 3为(69.29±6.19)%,CD 4为(34.35±4.18)%,CD 8为(40.14±4.60)%,CD 4/CD 8为1.48±0.31,物质生活为(30.63±2.19)分,躯体功能为(26.37±2.36)分,社会功能为(24.94±2.38)分,心理健康为(23.83±1.45)分,总分为(84.38±4.28)分。而参照组体质指数为(20.76±1.30)kg/m 2,白蛋白为(31.11±1.70)g/L,血清前白蛋白为(233.07±5.17) mg/L,CD 3为(56.23±6.12)%,CD 4为(31.26±3.50)%,CD 8为(36.28±5.34)%,CD 4/CD 8为0.73±0.07,物质生活为(27.00±2.06)分,躯体功能为(24.08±2.32)分,社会功能为(20.15± 2.30)分,心理健康为(19.64±1.17)分,总分为(78.80±5.19)分。观察组各项指标均优于参照组,组间差异存在统计学意义( P<0.05)。 结论:血液透析患者实施认知行为模式结合膳食干预可改善患者营养状态,提升生活质量,具有临床应用价值。
目的:探讨手术室精细化护理联合协同护理模式在达芬奇机器人辅助胸腔镜手术中的应用效果。方法:选取郑州大学第一附属医院2021年7月至2022年10月行达芬奇机器人辅助胸腔镜手术治疗的患者104例,根据入院顺序分为研究组( n=52)和常规组( n=52)。常规组给予常规护理干预,研究组在常规组基础上给予手术室精细化护理联合协同护理模式,比较两组患者手术相关指标、心理状态[焦虑自评量表(SAS)、抑郁自评量表(SDS)]、应对方式、并发症发生率、护理满意度。 结果:研究组手术时间、住院时间均短于常规组,术中出血量小于常规组( P<0.05)。干预后,研究组与常规组比较SAS评分、消极应对、SDS评分较低,积极应对评分较高( P<0.05),研究组并发症发生率明显低于常规组,总护理满意度(96.15%)高于常规组(84.62%)( P<0.05)。 结论:手术室精细化护理联合协同护理模式应用于达芬奇机器人辅助胸腔镜手术中可减轻患者负性情绪,调节患者应对方式,预防并发症发生,提高治疗效果,提升患者护理满意度。
Objective:To investigate the effect of self-designed Zishen-Yuetong prescription in the treatment of patients with unexplained recurrent spontaneous abortion (URSA) under the guidance of the theory of kidney deficiency and evil Fu and its influence on hormone levels and natural killer (NK) cell expression level.Methods:A total of 94 patients with URSA admitted to our hospital from February 2020 to March 2022 were divided into the control group and the observation group by the method of random number table.Forty-seven patients in the control group were given dydrogesterone treatment, and 47 patients in the observation group were given dydrogesterone treatment and self-designed kidney-feeding formula based on the theory of kidney deficiency and evil Fu.The TCM syndrome score, hormone levels and NK cell expression level were compared between the two groups.Results:After the treatment, the clinical efficacy of the two groups was compared.The total effective rate of the control group was 68.09%, lower than that of the observation group which was 87.23%; and the total success rate of pregnancy protection of the control group was 61.70%, which was also lower than that of the observation group (85.11%).The differences between the two groups were significant ( P<0.05).After treatment, the levels of hormone estradiol (E2), blood chorionic gonadotropin (HCG) and progesterone (P) in two groups were higher, and the observation group were higher than those of the control group ( P<0.05).The expression levels of CD16 and CD56 in NK cells in both groups were decreased compared with those before the treatment, and the CD16 level in the observation group was lower than that in the control group ( P<0.05), while there was no significant difference in the expression level of CD56 between two groups ( P>0.05). Conclusions:Based on the theory of kidney deficiency and evil Fu, the combination of Zishen-yuetong prescription and dydrogesterone tablets has good efficacy in the treatment of URSA, which can improve hormone levels, regulate NK cell expression to reduce the killing effect, improve the microenvironment for fetal growth, and effectively improve the rate of pregnancy.
Objective:To study the effect of dapagliflozin on β cell function, glucose metabolism and renal fibrosis factor on in patients with early diabetes nephropathy (DN) .Methods:A total of 102 patients with early DN in our hospital from January 2021 to February 2022 were randomly divided into the control group (51 cases) and the observation group (51 cases).The glucose metabolism indexes and pancreatic islets of the two groups were compared.Results:After the treatment, the levels of fasting blood glucose, 2 h postprandial blood glucose, HbA1c, fasting insulin, homeostasis model insulin resistance index, serum monocyte chemoattractant factor 1, transforming growth factor in the observation group β1, tissue inhibitor of matrix metalloproteinase 1 were lower than those in the control group ( P<0.05).The levels of β cell function index was higher than that of the control group ( P<0.05).There was no significant difference in the incidence of hypoglycemia, nausea and vomiting, dizziness and headache between the two groups ( P>0.05). Conclusion:Dapagliflozin has a significant effect in the treatment of early DN patients, which can improve the state of glucose metabolism and improve the islets of pancreas β cell function, reduce the level of renal fibrosis factor, with high safety.
结节病是一种病因未明的多系统肉芽肿性疾病,以非干酪样坏死性上皮细胞肉芽肿为特征,可累及全身多个系统和器官 [1,2,3,4,5,6,7,8,9]。结节病的发病机制目前尚不明确,现有的资料认为具有遗传易感性的个体在环境因素影响下引起免疫功能失调,从而发生肉芽肿性反应 [1,8,10,11,12,13]。而根据所累及的器官不同,其临床表现亦不相同,以肺部和胸腔内淋巴结受累最为常见,通常表现为双侧肺门淋巴结肿大,肾损害较为少见,且常因缺少典型的临床表现而被忽略 [9,14]。本文作者报告一例病理表现为膜性肾病的肺、肾同时受累的结节病临床病例,并结合相关文献复习,对结节病肾脏损害的临床表现特点、病理特点及治疗转归进行总结,供临床参考。
目的:探讨糖尿病肾病综合征患者护理中推行临床护理干预方法的应用效果。方法:选取2018年4月1日至2022年10月31日期间在我院确诊且接受治疗的30例糖尿病肾病综合征患者作为研究对象,根据其入院护理顺序进行随机分组,参考组15例患者给予常规护理,干预组15例患者在常规护理的基础上给予临床护理干预,对比两组患者干预效果。结果:护理后,干预组患者住院指标、并发症发生率均低于参考组,生活质量满意、满意度均高于参考组,差异具有统计学意义( P<0.05)。 结论:糖尿病肾病综合征护理工作中采用临床护理干预方法可以强化护理作用,改善患者预后,使患者在住院期间生活质量与满意度均得到提升。