《黑龙江医学》杂志创刊于1972年,是由黑龙江省卫生健康委员会主管、黑龙江省卫生健康发展研究中心主办、国内外公开发行的医药卫生综合学术期刊.《黑龙江医学》读者对象主要为各级各类医疗卫生机构的卫生技术人员,卫生行政管理人员,医学院校、科研机构从事教学、科研的工作人员.本刊的办刊宗旨是:贯彻党的卫生与健康工作方针,坚持理论与实践相结合,普及与提高相结合,全面反映黑龙江省医学发展水平,报道黑龙江省及全国临床医学、基础医学、康复医学、护理学等研究的新成果、新经验和新方法,介绍国内外医学科技动态和进展,为医学事业发展服务.
Objective:Color Doppler ultrasound technology was applied to the diagnosis of breast cancer to analyze its efficacy in diagnosing microcalcification conditions.Methods:The clinical data of 122 breast cancer patients who underwent physical examination in the health management center of the sample hospitals from March 2020 to March 2022 were retrospectively analyzed and divided in to malignant guoup of 65 cases and benign group of 57 cases according to the image results.The imaging performance,the different nature of calcifications,and the sensitivity,specificity,and accuracy of microcalcifications diagnosis under color Doppler ultrasound high-frequency diagnosis were analyzed.Results:The number of patients with burr phenomenon,irregular mass shape,microcalcifications,blurred borders,and blood flow grade 2 and 3 in the malignant group had more tumor margins than in the benign group,with statistically significant differences(χ2=5.667,5.634,9.332,4.541,7.882,P＜0.05).Microcalcifications and arcuate calcifications were higher in the malignant group than in the benign group,with statistically significant differences(χ2=11.224,14.235,6.342,P＜0.05).There was no statistically significant difference in coarse calcification in the malignant group compared with the benign group(χ2=1.341,P＞0.05).The specificity of color Doppler ultrasound in diagnosing microcalcifications in breast cancer was 89.47%,sensitivity was 93.94%,and accuracy was 92.94%.Conclusion:The application of color Doppler ultrasound technology in the diagnosis of breast cancer microcalcifications can be of good value and is at a high level of specificity,sensitivity,and accuracy.
Objective:To explore the status of adolescent health checkups in Heilongjiang Province and to analyze the abnor-malities.Methods:Health checkups were conducted for 1981 adolescents in Heilongjiang Province from May 2019 to July 2023 in accordance with the hospital's self-designed checkup forms and programs.Results:The top percentages of abnormalities in screening programs were,in order,systolic blood pressure,electrocardiogram,eye disease,BMI,naked eye vision,diastolic blood pressure,abdominal ultrasound,heart rate,ALT,and psychosomatic testing.Health problems were centered on high blood pressure,poor vision,fatty liver,obesity,heart disease,and psychosomatic abnormalities.Logistic regression analysis showed that age,body weight,systolic blood pressure,naked-eye visual acuity around,and ocular disease were significant influences on the examination results(OR=0.780,1.120,1.190,0,0,P＜0.05).Conclusion:Heilongjiang Province is a cold region,and cardiovascular disease,eye disease,obesity,fatty liver,and liver function abnormalities are the main health problems in adolescents,and age,body weight,systolic blood pressure,naked-eye visual acuity,and eye disease are the important influencing factors affecting the results of the examination.
Objective:To summarize the practical experience of balanced fire cupping technique training for nursing staff in Chinese medicine hospitals,and to enhance the ability of Chinese medicine nursing staff to apply cupping-type techniques to identify evidence.Methods:The Balanced Fire Jar Technology Group was established,and the group implemented internal management,developed management systems and training programs,and organized their implementation.The training program focused on developing the ability of cupping-type techniques to identify and apply evidence for the members of the group,including 3 modules on basic knowledge of Chinese medicine,technical operation,and clinical practice,covering observation of illnesses,the doctrine of Tibetan phenomena,the doctrine of meridians and collaterals,key points in identifying evidence,case writing,and nursing outpatient follow up.Results:After 30 months of training,the standardized process of balanced fire cupping technology was constructed,and the members of the school group mastered various techniques of cupping and the operation process of balanced fire cupping to achieve the homogenization of the operation of the members of the school group.12 protocols for the clinical application of balanced fire cupping technology were sorted out.Conclusion:Through the implementation of the teaching mode of the Balanced Fire Cupping Technology Group,the theoretical level of TCM nursing and the ability of clinical practice of TCM nursing staff were effectively enhanced,and the implementation mode of the Balanced Fire Cupping Technology Group provided effective reference for the standardized training and promotion of the application of TCM nursing technology.
Objective:To assess the efficacy of montelukast sodium combined with budesonide nebulized inhalation on commu-nity-acquired pneumonia and airway hyperresponsiveness in children.Methods:102 cases of community-acquired pneumonia ad-mitted to the hospital from January 2019 to January 2022 were selected for the study,and were divided into the experimental group and the conventional group according to the random number table method,with 51 cases in each group.The conventional group was treated with budesonide and the experimental group was treated with montelukast sodium on the basis of the conventional group.Children in both groups were treated continuously for 7 d.Eosinophil cationic protein(ECP)and interleukin-4(IL-4)levels were collected and measured within 24 h(before treatment)and 1 week after treatment,respectively.After 7 d of treatment,the clinical efficacy of the two groups was evaluated,and the occurrence of adverse reactions during treatment was recorded.Results:The serum ECP and IL-4 levels of children in both groups were lower than those before treatment,and the difference was statisti-cally significant(t=5.247,6.741,P＜0.05),and the experimental group was lower than the conventional group,and the difference was statistically significant(t=6.044,22.808,P＜0.05).The total effective rate of the experimental group(94.12%)was higher than that of the conventional group(78.43%),and the difference was statistically significant(χ2=4.129,P＜0.05).The difference in the total incidence of adverse reactions between the two groups of children was not statistically significant(χ2=2.124,P＞0.05).Con-clusion:In the treatment of community-acquired pneumonia in children with montelukast sodium combined with budesonide nebu-lized inhalation,the effect is more obvious,significantly improve the symptoms of the children,at the same time,it can effectively alleviate the hyperresponsiveness of the children's airway,promote the rapid recovery of the children,and it is safe and reliable.
Objective:To investigate the analgesic effect of ultrasound-guided erector spinae plane block(ESPB)in posterior extraperitoneal laparoscopic surgery and the effect on vital sign indicators,cisual analog scale(VAS)pain score,and comfort score.Methods:145 patients admitted to the hospital for retroperitoneal episiotomy from January 2020 to June 2022 were selected for the study and were divided into control group(n=72)and observation group(n=73)using the random number table method.The control group received general anesthesia with tracheal intubation,and the observation group received general anesthesia with tracheal intubation preceded by ultrasound-guided ESPB.The vital signs(heart rate and mean arterial pressure),pain level(VAS score),comfort level scale(BCS)score,and adverse effects were compared between the two groups.Results:There was no statistically sig-nificant difference in heart rate and mean arterial pressure between the two groups of patients at t1,t2,t3 and t4(t=1.6834,1.8482,1.7399,1.7494,0.6387,0.7817,1.5779,0.5542,P＞0.05).The VAS scores at 3 h,12 h,and 24 h postoperatively were low-er in the observation group than in the control group,with statistically significant differences(t=34.6829,36.1259,28.9776,P＜0.05).The BCS scores at 3 h,12 h,and 24 h postoperatively were higher in the observation group than in the control group,with statistically significant differences(t=100.4104,49.0955,45.8380,P＜0.05).The incidence of adverse reactions in the observa-tion group was lower than that in the control group,and the difference was not statistically significant(χ2=0.1139,P＞0.05).Con-clusion:The application of ultrasound-guided ESPB to extraperitoneal laparoscopic surgery was safe and effective with good postop-erative analgesia and high patient comfort.
目的:观察特殊心理干预对女性双相情感障碍(BD)患者月经期病情的影响.方法:选取2019年10月—2021年8月赣州市第三人民医院收治的79例女性BD患者,依据随机数表法分为两组,研究组39例,对照组40例.对照组患者给予常规护理干预,在此基础上研究组患者采用特殊心理干预,均干预4周;比较两组患者精神症状[阳性与阴性症状量表(PANSS)]、焦虑、抑郁状况[焦虑自评量表(SAS)、抑郁自评量表(SDS)]、自尊水平[自尊量表(SES)]、认知功能[韦氏成人记忆量表(WMS-IV)和韦氏成人智力量表(WAIS-RC)]、日常生活能力[日常生活能力评定量表(ADL)]和生活质量[世界卫生组织生活质量量表(WHOQOL)].结果:干预4周后,两组患者PANSS中阳性症状、阴性症状、一般精神病症状评分均低于干预前,且研究组低于对照组,差异有统计学意义(t=6.178、8.361、4.894,P＜0.05);干预4周后,两组患者SAS、SDS评分均低于干预前,且研究组低于对照组,差异有统计学意义(t=7.099、4.672,P＜0.05);干预4周后,两组患者SES、WMS-IV、WAIS-RC评分均高于干预前,且研究组高于对照组,差异有统计学意义(t=4.185、3.311、9.261,P＜0.05);干预4周后,两组患者ADL评分、WHOQOL评分均高于干预前,且研究组高于对照组,差异有统计学意义(t=5.226、6.085,P＜0.05).结论:对女性BD患者进行特殊心理干预可缓解月经期精神症状,改善焦虑、抑郁状况,提高自尊心及认知能力,促进患者日常生活能力及生活质量的提升.
目的:观察乳腺钼靶联合超声对乳腺良恶性疾病的鉴别诊断,旨在为基层医疗单位开展乳腺癌的早期筛查提供数据参考,以最大限度降低经济欠发达地区女性乳腺癌死亡率.方法:选取2021年6月—2022年4月阳春市中医院收治的110例疑似乳腺癌患者作为研究对象,所有患者均分别采用乳腺钼靶与彩色多普勒超声检查.比较患者乳腺钼靶、超声单独与联合诊断乳腺良恶性疾病的敏感度、特异性与准确度.结果:110例疑似乳腺癌患者经病理检查后12例(10.91%)表现为恶性病变,98例(89.09%)表现为良性病变.乳腺钼靶与超声联合检查的诊断敏感度(91.67%)高于乳腺钼靶(41.67%)与超声(58.33%)单独检查;乳腺钼靶与超声联合检查的诊断特异性(98.98%)略高于乳腺钼靶(94.90%)与超声(94.90%)单独检查;乳腺钼靶与超声联合检查(98.18%)的诊断准确度高于乳腺钼靶(89.09%)与超声(90.91%)单独检查.结论:乳腺钼靶与超声单独应用于乳腺良恶性疾病的鉴别诊断存在一定局限,可能造成较多的漏诊与误诊发生,两者联合诊断的敏感度、特异性及准确度较高,对乳腺良恶性疾病的早期鉴别及后续治疗方案的制定与实施具有重要意义.
Objective:To investigate the clinical effect of gynecological Qianjin capsule combined with letrozole in the treat-ment of polycystic ovary syndrome(PCOS)with infertility.Methods:88 cases of PCOS infertility patients admitted to the hospital from February 2017 to January 2019 were selected for the study,and were divided into the control group and the observation group using the random number table method,with 44 cases in each group.The patients in the control group were treated with letrozole,and the patients in the observation group were treated with gynecological Qianjin capsule on the basis of the control group.The clinical efficacy,clinical related indexes,sex hormone level,ovulation rate,pregnancy rate and the incidence of adverse reactions were compared between the two groups.Results:The total effective rate of treatment in the observation group was 90.91%(40/44),which was higher than 63.64%(28/44)of the control group,and the difference was statistically significant(χ2=9.318,P＜0.05).The endothelial thickness of patients in the observation group was(9.84±1.17)mm,the number of dominant follicles was item(2.76±0.59),and the number of ovulation was(2.52±0.92),which were greater than(7.83±0.88)mm,(1.24±0.43),and(1.24±0.56)in the control group,and the difference was statistically significant(t=9.107,13.810,7.883,P＜0.05).The serum follicle stimulating hormone(FSH)of(5.43±0.83)U/L,luteinizing hormone(LH)of(6.94±0.76)U/L,testosterone(T)of(1.58±0.33)nmol/L in patients of the observation group was lower than those of the control group after treatment,and the estradiol(E2)of(96.74±10.18)ng/L was higher than(90.28±9.91)ng/L of the control group,the differences were statistically significant(t=4.477,10.644,3.016,6.706,P＜0.05).The ovulation rate of the observation group was 95.45%(42/44)and the pregnancy rate was 86.36%(38/44),which were higher than the 63.64%(28/44)and 52.27%(23/44)of the control group,and the difference was statistically significant(χ2=34.189,12.022,P＜0.05).The rate of adverse reactions in the observation group was 11.36%(5/44),which was lower than 27.27%(12/44)in the control group,and the difference was statistically significant(χ2=4.470,P＜0.05).Conclusion:Gynecological Qianjin Capsules combined with Letrozole in the treatment of PCOS with infertility can effectively improve the patients'hormone level,increase the thickness of the endothelium,the number of dominant follicles and the number of ovulation,which is conducive to improving the success rate of pregnancy.
Objective:To analyze the effect of exercise rehabilitation on the improvement of LVEF levels in elderly patients with chronic heart failure(CHF).Methods:80 patients were randomly divided into control group and experimental group,40 cases in each group.The control group carried out conventional nursing,and the experimental group carried out exercise rehabilitation nursing.Cardiac function indexes,heart rate,6-minute walk test(6 MWT)and quality of life scores were compared between the two groups.Results:Before the intervention,there was no statistically significant difference in cardiac function indices between the test and control groups(t=0.1542,0.5020,0.1070,P＞0.05).After the intervention,the left ventricular end-diastolic internal di-ameter(LVESD)and left ventricular ejection fraction(LVEF)of the test group were higher than those of the control group,and the left ventricular end-systolic internal diameter(LVEDD)was lower than those of the control group,and the differences were statisti-cally significant(t=4.4450,3.6952,6.6206,P＜0.05).After the intervention,the 6 MWT of both groups was longer than the pre-intervention time,and the heart rate was lower than the pre-intervention time,in which the changes in the experimental group were better than the control group,and the difference was statistically significant(t=11.8733,7.0324,P＜0.05).Before the inter-vention,there was no statistically significant difference in all quality of life scores between the two groups(P＞0.05).After the in-tervention,all the quality of life scores of the patients in the two groups were higher than those before the intervention,and the psy-chological state,health level,somatic function,and social function scores of the patients in the experimental group were higher than those of the control group,and the difference was statistically significant(t=9.1034,8.9950,15.6503,10.8665,P＜0.05).Conclusion:Active exercise rehabilitation nursing facilitates the improvement of cardiac function in elderly patients with chronic heart failure and enhances their quality of life.
Gallstones are highly prevalent in the population and are associated with advanced age,female,diet,obesity and genetics.Comprehensive treatment,mainly surgical,is the treatment of choice.With the popularization of the concept of rapid surgical recovery and the development of minimally invasive treatment techniques such as laparoscopy and endoscopy,minimally invasive treatment for patients with gallstones is gradually being developed.Although approximately 90%of gallstones can be managed by conventional traditional techniques,however,there are still 10%to 15%of cases in which stone extraction fails due to the presence of refractory bile duct stones.For these patients,mechanical lithotripsy,liquid electrolysis,extracorporeal shock wave lithotripsy,and laser lithotripsy can be used to assist in the management of refractory gallstones,and more satisfactory results have been obtained in terms of stone removal rate,operation time,intraoperative bleeding,and complication rate,showing the advantages of lithotripsy to assist in the management of refractory gallstones.Therefore,the paper reviews the research progress of different lithotripsy procedures in the adjunctive management of refractory gallstones in recent years,hoping to provide a reference for the implementation of lithotripsy methods and strategies in the treatment of patients with refractory gallstones.
Medical humanities education is an important theme for the in-depth educational reform of China's higher medical colleges and universities in the 21st century.Medical students are the force behind the grand blueprint of the national strategy of"Healthy China"and the promotion of the construction of a healthy China,shouldering the mission of laying the foundation for the great rejuvenation of the Chinese nation through health.Strengthening medical humanities education for medical students in colleges and universities of higher medicine is urgent to meet the needs of the times.By explaining the value requirements of strengthening medical humanities education in colleges and universities of higher education,we objectively examine the current situation and problems of medical humanities education in colleges and universities of higher education in China,and put forward useful countermeasures to strengthen and improve the humanities education of medical students,so as to help the reform of medical humanities education in colleges and universities of higher education and the construction of a healthy China.
Objective:To observe the effect of pre-treatment with leuprolide in patients with uterine fibroids before excisional surgery to provide a clinical basis.Methods:The general data of 127 patients with uterine fibroids admitted to the hospital from January 2021 to January 2022 were retrospectively analyzed and divided into treatment group(n=65)and conventional group(n= 62)based on different treatment methods.In the treatment group,leuprolide was injected subcutaneously intramuscularly before surgery,and patients in both groups underwent laparoscopic myomectomy.The intraoperative indexes,postoperative indexes,hormonal status,and prognosis of the patients in the two groups were compared.Results:Intraoperative bleeding,pelvic drainage,postoperative bed and hospital stay were lower in the treatment group compared with the conventional group,with statistically significant differences(t=10.378,5.385,25.057,46.362,P＜0.05).After surgery,folliculogenic hormone(FSH),luteinizing hormone(LH),estradiol(E2),and progesterone(P)improved better and were closer to normal control criteria in the treatment group,with statistically significant differences(t=14.447,13.719,3.731,5.197,P＜0.05).After surgery,the risk of complications was lower in the treatment group,with a statistically significant difference(χ2=0.754,P＜0.05).During post-treatment follow-up,the treatment group had better improvement in menstrual cycle,menstrual volume and uterine volume,with statistically significant differences(t=64.830,4.564,8.801,P＜0.05).Conclusion:The use of leuprolide as preoperative pretreatment for myomectomy is more effective and has positive implications for promoting postoperative recovery and improving patient prognosis.
Objective:To investigate the efficacy and effect on inflammatory mediators,renal function indices,and safety of Shuotong mirror combined with ultramicrochannel percutaneous nephrolithotripsy(SMP)in the treatment of patients with complex upper ureteral and renal stones.Methods:98 patients with complex upper ureteral and renal stones admitted to the hospital from December 2019 to January 2022 were selected for the study,and the patients were randomly divided into the combined group(n= 49,given Shuotong mirror combined with SMP)and the conventional group(n=49,given conventional lithotripsy).The stone removal effect,surgical indexes and safety were observed.The preoperative and 3 d postoperative inflammatory mediators(interleukin[IL-6],monocyte chemotactic protein-1[MCP-1],C-reactive protein[CRP]),renal function indexes(kidney injury molecule-1[KIM-1],neutrophil gelatinase-associated lipid transport protein[NGAL],and β2-microglobulin[β2-MG])were compared.Results:Postoperatively,the 1-time stone clearance rate of patients in the combined group was higher than that of the conventional group,and the difference was statistically significant(χ2=6.376,P＜0.05).The first time out of bed and hospitalization time of patients in the combined group were shorter than those in the conventional group,and the differences were statistically significant(t=3.562,2.172,P＜0.05).Patients in the combined group had lower CRP,MCP-1,and IL-6 than those in the conventional group,and the difference was statistically significant(t=3.428,3.010,2.135,P＜0.05).Patients in the combined group had lower KIM-1,NGAL,and β2-MG than those in the conventional group,and the difference was statistically significant(t=3.608,3.003,3.440,P＜0.05).The occurrence of complications in patients in the combined group was lower than that in the conventional group,and the difference was statistically significant(χ2=4.356,P＜0.05).Conclusion:Shuotong mirror combined with SMP for the treatment of complex upper ureteral and renal stones optimizes the surgical path,improves short-term efficacy,reduces inflammatory response,helps to protect renal function,and improves therapeutic safety.
Objective:To investigate the effects of cognitive-behavioral therapy-based bicentric care applied to acute myocardial infarction patients after percutaneous coronary intervention(PCI)on cardiac function and negative emotions.Methods:64 cases of post PCI patients with acute myocardial infarction admitted to the hospital from June 2020 to June 2021 were selected as the study subjects,and were divided into sub-study group and control group by randomized number table method,with 32 cases in each group.The control group used conventional nursing care,and the study group was given cognitive behavioral therapy-based bicentric nursing care on the basis of the control group,and both groups of patients continued to be treated for 2 weeks and then evaluated the effects.Before and after care,Philips epiq5 color Doppler ultrasonography was used to detect ejection fraction(EF)and per beat output(SV)cardiac function values of the two groups of patients,and the Hospital Anxiety and Depression Scale(HADS)was used to assess the patients'anxiety and depression and the occurrence of complications during the treatment period of the two groups of patients was compared.Results:Before nursing care,there was no statistically significant difference in the comparison of EF and SV levels between the two groups(t=0.545,0.874,P＞0.05).After the nursing care,the EF and SV levels of patients in both groups increased compared with those before the nursing care,and the study group was higher than the control group after the nursing care,and the difference was statistically significant(t=4.792,6.854,P＜0.05).Before care,there was no statistically significant difference in HADS between the two groups(t=0.216,P＞0.05).After the care,the HADS of patients in both groups were lower than before the care,and the HADS of the study group was lower than that of the control group,and the difference was statistically significant(t=6.254,5.985,P＜0.05,t=8.998,P＜0.05).The complication rate in the study group was lower than that in the control group,and the difference was statistically significant(χ2=3.952,P＜0.05).Conclusion:Cognitive behavioral therapy-based bicentric care can significantly improve patients'cardiac function,alleviate anxiety and depression,and reduce the incidence of complications.
Osteoporosis(OP),as a common clinical bone disease,has a close correlation between its occurrence and develop-ment and the patients'age,so patients are commonly found in postmenopausal women and elderly men.The OP patient base has continued to grow in recent years due to the aging of our population,and one of its most serious complications,osteoporotic frac-ture,has a relatively high risk of disability and death.Osteoporotic vertebral compression fracture(OVCF)has the highest percentage of osteoporotic fracture types,and its triggering factor is considered to be the decrease in vertebral bone mineral density(BMD)due to OP,which leads to a decrease in bone mass and strength,and the fracture may be induced by slight external force at this stage,or by no obvious external force.At this stage,clinical consensus and guidelines for the diagnosis and treatment of OVCF have been formed,and related work has been widely carried out,but there is still the problem of insufficient standardization of implementa-tion.Based on this,the article reviews the diagnosis and treatment of OVCF with the data of previous studies,aiming to provide reference for related personnel.
Objective:To investigate the role of TM6SF1 gene in lung adenocarcinoma cells.Methods:The expression of TM6SF1 gene in lung adenocarcinoma and normal tissues was analyzed by GEPIA database.Cell proliferation assay was performed to detect the proliferation of A549 cells after overexpression of TM6SF1.Wound-healing?assay was used to test the speed of wound healing after over-expressing TM6SF1.Transwell cell assay to detect A549 cell invasion and migration after overexpression of TM6SF1.Results:Analysis of the GEPIA database revealed that the expression of TM6SF1 was reduced in lung adenocarcinoma compared with normal tissues,with statistically significant difference(*P＜0.05,**P＜0.01,***P＜0.001),and the survival was longer in the group with high expression of TM6SF1.TM6SF1 negatively correlated with the cell proliferation-associated nuclear antigen Ki-67.After overexpression of TM6SF1,the proliferation,invasion and migration of A549 cells were inhibited,with statisti-cally significant difference(*P＜0.05,**P＜0.01,***P＜0.001),and the expression of PI3K/Akt pathway-associated kinases was down-regulated.Conclusion:The TM6SF1 gene may act as an oncogenic factor in lung adenocarcinoma.
Objective:To investigate the value of high-risk human papillomavirus(HPV)combined with liquid-based thin-layer cytology testing technology(TCT)in the early screening of cervical lesions in primary care women.Methods:A stratified sampling method was used to select 5160 female cervical exfoliated cell samples from two townships in Boluo County,Huizhou City,from January to June 2021.High-risk HPV-DNA(PCR-fluorescent probe method)and TCT tests were used to screen positive individu-als,followed by colposcopic pathology,and the diagnostic efficacy of both methods in the early screening of cervical lesions was an-alyzed.Results:The positive rate of high-risk HPV screening in the population was 7.27%,of which HPV16 and HPV18 account-ed for 27.2%,and the positive predictive value of both was much higher than the positive predictive value of the other 13 high-risk types.The positive rate of TCT screening was 4.46%,and the positive predictive value was proportional to the degree of cytopathy.The positive predictive value of HPV combined with TCT testing was 98.34%,which was higher than the positive predic-tive value of HPV or TCT alone,and the difference was statistically significant(P＜0.05).Conclusion:High-risk HPV combined with TCT can improve the diagnostic efficacy of early screening of cervical lesions in the population,and has important application in the early screening and prevention of cervical lesions in primary women.
目的:探讨生长抑素(SS)联合艾司奥美拉唑(ESOM)对重症急性胰腺炎(SAP)患者炎症指标及肠道黏膜屏障功能的影响.方法:选择2020年1月—2021年12月江西省上犹县人民医院治疗的62例SAP患者作为研究对象,按随机数表法分为对照组和观察组,每组各31例.对照组采用ESOM治疗,观察组采用SS联合ESOM治疗.比较两组患者临床疗效、临床症状缓解时间、病情改善情况、健康状况、炎症指标、肠道黏膜屏障功能及不良反应发生率.结果:观察组治疗总有效率(RR)高于对照组,差异有统计学意义(χ2=4.292,P＜0.05).观察组腹胀缓解时间、发热缓解时间、腹痛缓解时间及恶心呕吐缓解时间均短于对照组,差异有统计学意义(t=2.540、2.315、2.299、2.702,P＜0.05).治疗后,观察组Ranson评分及APACHEⅡ评分均低于对照组,差异有统计学意义(t=3.683、2.662,P＜0.05).治疗后,观察组反应蛋白(CRP)及肿瘤坏死因子-α(TNF-α)水平均低于对照组,差异有统计学意义(t=2.903、2.326,P＜0.05).治疗后,观察组内皮素(ET)、二胺氧化酶(DAO)、D-乳酸(D-LA)水平均低于对照组,差异有统计学意义(t=2.389、3.845、3.955,P＜0.05).两组患者不良反应发生率比较,差异无统计学意义(χ2=0.144,P＞0.05).结论:SS联合ESOM治疗可降低SAP患者CRP、TNF-α、ET、DAO、D-LA水平,改善患者治疗效果,减轻其临床症状,加快其病情恢复,且不良反应发生率并未增加.
Objective:To investigate the effect of Orem self-care model combined with routine functional exercises on compliance and satisfaction with care in patients with pelvic fractures.Methods:104 cases of pelvic fracture patients received in the hospital from January 2021 to January 2022 were selected as the study subjects,and were divided into the control group(52 cases)and the observation group(52 cases)based on the random number table method.The control group implemented conventional functional exercises,and the observation group implemented the Orem self-care model combined with conventional functional exercises.The recovery time as well as hospitalization time,treatment compliance rate and patient care satisfaction were compared between the two groups.Results:The difference in recovery time as well as hospitalization time between the two groups was statistically significant(t=9.377,10.782,P＜0.05).The treatment compliance rate of the observation group was higher than that of the control group,and the difference was statistically significant(χ2=4.727,P＜0.05).Satisfaction of the observation group was higher than that of the control group,and the difference was statistically significant(χ2=5.283,P＜0.05).Conclusion:Implementation of the Orem self-care model combined with routine functional exercises for patients with pelvic fractures promotes rapid recovery and contributes to improved adherence as well as satisfaction with treatment.
