Results obtained from comparative studies of the structures of humic acids from peats of different origins in the Tomsk area by infrared spectroscopy are presented. These data showed that the IR spectra of humic acids extracted from different types of peat had high levels of similarity, demonstrating similarities in their chemical structures. Humic acid from lowland woody-grassy peat had very significant differences from other types of peat and consisted of compounds with high proportions of aliphatic fragments and, perhaps, lower benzenoid levels, as well as higher contents of active acid groups (carboxyl, hydroxyl).

In article results of comparative studying of structure of humic acids of peats of a various origin of Tomsk area are resulted by a method of infra-red spectroscopy. It is shown, that IR-spectra of the humic acids taken from different types of peat, have a high degree of similarity that specifies affinity of their chemical structure. It is established, that humic acids low-moor woody-grassy type of peat have rather significant differences from other types of peat and represent connections with a high share aliphatic fragments and it is possible a smaller degree benzenoid, and also with the high contents of active sour groups (carboxylic, hydroxyl).

In the article results of research of a chemical structure of humic acids of low moor woody grassy type of peat of Tomsk area are resulted by methods of the elemental analysis and infra red spectroscopy. In this work results of toxicological research of humic acids also are described: acute toxicity, pathomorphology and flow properties of blood. It is shown, that humic acids of low moor woody grassy type of peat represent connection with a high share aliphatic fragments submitted long connected by circuits, have a small degree benzenoid, contain active oxygen and nitrogen containing functional groups (carboxylic, hydroxyl, amides, amino groups). It is established, that humic acids at intragastric introduction are nontoxic substances. At intraperitoneal introduction of lethal dozes the destruction of animals comes from acute intimate insufficiency, thus the cause of acute infringement hemodynamics can be negative influence of humic acids on flow properties of blood.

The possibility of use of sodium humat as a haemostatic agent was suggested based on its effects on reversible RBC aggregation.

The efficacy of ointment with sodium gumat from peat was evaluated on experimental model of ultraviolet inflammation and allergic reactions by passive skin anaphylaxis. It was found that sodium gumat on both models was as effective as best comparable drugs such as solkoseril and beladerm.

Sodium humate from peat of Tomsk region was tested on three animal models of allergic reaction. It was found that sodium humate suppresses the development and reduces the intensity of anaphylactic shock in guinea pigs and decreases the intensity of the delayed hypersensitivity reaction to goat erythrocytes. It is suggested that sodium humate can be a promising substance for the treatment of allergic states.

The hemorheological activity of a dry extract from Rhaponticum (Leuzea) carthamoides (Willd.) Iljin. was studied in spontaneously hypertensive rats (SHRs). A 14-day treatment of the test rats with a daily dose of 150 mg/kg improved the rheological characteristics, as manifested by a reduced viscosity of the whole blood and plasma, increased spontaneous erythrocyte aggregation and fibrinogen concentration, and increased erythrocyte deformability and electrophoretic mobility against the untreated control level.

The hemorrheological effects of extracts from Maltese cross campion (Lychnis chalcedonica L.) prepared using 40% (I) and 70% (II) aqueous ethanol solutions were studied in vitro in comparison with tanakan on the model of high blood viscosity syndrome. Under the hyperthermia conditions, extracts I and II at a concentration of 1 x 10(-5) g/ml limited the growth of blood viscosity and thrombocyte aggregation and the drop in thrombocyte deformability. The effects of both extracts were comparable to those of tanakan. Prolonged (5 days) administration of extract I (daily dose, 150 mg/kg p.o) in rats with arterial hypertension (SHR) decreased the viscosity of whole blood and plasma, reduced the concentration of fibrinogen, and increased the deformability of erythrocytes. No reliable effects of the extracts in vivo upon the erythrocyte aggregation and hematocrit were observed.