目的 探讨脐动脉血流收缩期峰值流速/舒张末期流速(S/D)值测定结合胎心监护在诊断胎儿宫内窘迫中的应用价值.方法 回顾性分析2017年1月~2018年11月于我院住院分娩的60例孕妇的临床资料,均经脐动脉血流S/D值测定及胎心监护,根据检测结果分为两者均异常组(13例)、S/D值异常组(9例)、胎心监护异常组(6例)、均正常组(32例).比较四组胎儿宫内窘迫发生率及妊娠结局情况;与临床病理结果比较,分析脐动脉血流S/D值测定结合胎心监护对胎儿宫内窘迫的诊断价值.结果 四组间胎儿宫内窘迫、羊水污染、剖宫产及新生儿窒息的发生率有明显差异,其中脐动脉血流S/D值及胎心监护均异常组上述指标的发生率均明显高于另外三组(均P<0.05).脐动脉血流S/D值联合胎心监护诊断胎儿宫内窘迫的灵敏度、特异度和准确性均高于单一的脐动脉血流S/D值测定和胎心监护.结论 脐动脉血流S/D值测定结合胎心监护对胎儿宫内窘迫具有较高的诊断价值,对防止不良妊娠结局、改善围产儿预后均有重要意义.
目的 分析运用气囊仿生助产术提高瘢痕子宫经阴道分娩成功率的有效性.方法 从2016年3月~2017年3月期间我院接收的瘢痕子宫再次足月妊娠阴道分娩产妇中随机选取200例作为本文研究对象,将其分为对照组98例和实验组102例.为对照组产妇进行常规阴道助娩,为实验组产妇运用气囊助产术助娩,观察并比较两组产妇的分娩成功情况.结果 经过助娩,实验组产妇经阴道分娩成功率为91.18%,对照组产妇的分娩成功率为77.55%,气囊仿生助产术助娩较常规阴道助娩更能促进瘢痕子宫产妇分娩成功率的提高,经SPSS19.0统计学软件分析得出χ2=7.08,P<0.01;实验组产妇的第一产程时间、第二产程时间、总产程时间均明显少于对照组产妇的相应时间,差异具有统计学意义(P<0.05).结论 运用气囊助产术可有效提高瘢痕子宫产妇阴道分娩成功率,使瘢痕子宫产妇的产后出血量控制在正常水平范围内,产后无大出血、会阴血肿、尿潴留等并发症,新生儿的Apgar评分在7~10分范围内,临床医学界应对气囊助产术进行大力推广.
选取在我院产检的孕妇6200例进行研究,孕妇首次接受检查的妊娠期均在11~14w,常规超声检查的同时联合胎儿颈项透明层、静脉导管及三尖瓣频谱检查。结果171例颈项透明层增厚的胎儿后期诊断为先天性心脏畸形的44例,占25.73%(44/171),6029例颈项透明层正常胎儿后期诊断为先天性心脏畸形的53例,占0.88%(53/6029),差异有统计学意义(P<0.01)。182例静脉导管血流频谱异常的孕妇于妊娠的18~20w检测确诊为先天性心脏畸形的23例,发生率为12.6%,6018例静脉导管血流频谱正常的孕妇检测出先天性心脏畸形的33例,发生率为0.55%,差异有统计学意义(P<0.01)。108例三尖瓣反流的孕妇于妊娠的18~20w检测确诊为先天性心脏畸形的18例,发生率为16.7%,6092例三尖瓣频谱正常的孕妇检测出先天性心脏畸形的32例,发生率为0.53%,差异有统计学意义(P<0.01)。胎儿颈项透明层、静脉导管及三尖瓣频谱的超声检测在孕妇早期的筛查中具有十分高的应用价值,对于先天性心脏畸形的早期诊断有较高的参考意义。
选取我院2012年10月~2014年10月收治的子宫内膜异位症患者150例作为研究对象,按照数字随机法分为观察组和对照组,每组75例。对照组单纯给予腹腔镜手术治疗,观察组患者给予腹腔镜手术联合孕三烯酮治疗。观察两组患者的临床疗效、不良反应和病情复发情况,并作对比分析。结果观察组患者临床治疗总有效率为90.7%,显著高于对照组的72%,差异显著(P<0.05);且观察组患者不良反应发生率明显低于对照组,差异显著(P<0.05);观察组病情复发率为4%,明显低于对照组的21.3%,差异显著(P<0.05)。采用腹腔镜手术联合孕三烯酮治疗子宫内膜异位症具有较高的临床应用价值,能够有效提高治疗有效率,减少不良反应,安全可靠,值得临床大力推广。
目的:研究胎儿生长受限( FGR)与胎盘组织结构改变关系。方法:采用前瞻性病例对照的方法进行研究,取被诊断为FGR的孕妇30例作为研究组,同时正常孕妇30例作为对照组,分析两组孕妇产后胎盘重量、胎盘系数以及胎盘的病理改变。结果:①妊娠期FGR组和对照组胎盘平均重量[(446.78±33.5)g vs(537.46±62.4)g]、新生儿体重[(2200±270)g vs(3225±487)g]及胎盘系数[(0.202±0.020)vs(0.166±0.062)]比较,差异均有统计学意义(P<0.05)。②FGR组与对照组出现绒毛内血管及间质纤维,绒毛间血栓甚至胎盘梗死等一系列胎盘病理改变现象,两组比较差异均有统计学意义( P<0.05)。结论:FGR在显微镜下可见出现绒毛内血管及间质纤维,绒毛间血栓甚至胎盘梗死等一系列胎盘病理改变现象等变化,这些改变可能是胎盘本身在缺氧状态下的一系列调整。
目的:探究分析对人流术后预防宫腔粘连采用几丁糖进行治疗的临床效果。方法选取我院2012年2月---2013年7月收治的220例人工流产患者作为临床研究对象,根据入院编号的偶数将其分为治疗组和对照组,各110例,对照组患者不采用几丁糖进行治疗,治疗组患者采用几丁糖进行治疗,对两组患者的月经量减少、宫腔粘连发生率以及闭经等情况进行观察对比。结果治疗组患者的月经减少量、闭经发生率显著低于对照组( P <0.05);治疗组患者的宫腔粘连发生率明显低于对照组(P<0.05)。结论对人流术患者采用几丁糖治疗,能够有效降低宫腔粘连发生率,降低月经量减少与闭经发生率,预防宫腔粘连的效果较为明显,值得临床推广。
目的 探讨分析盐酸利托君和硫酸镁治疗先兆早产临床疗效.方法 选取先兆早产孕妇66例随机分为两组,对照组32例接受硫酸镁治疗,观察组34例接受盐酸利托君治疗,对比两组临床疗效与不良反应.结果 治疗后,观察组患者在显效时间、孕龄延长时间、新生儿体重、Apgar评分、足月分娩率上均显著高于对照组(P<0.05),产后出血量显著低于对照组(P<0.05),两组不良反应发生率差异无统计学意义(P>0.05).结论 盐酸利托君在先兆早产治疗中临床疗效确切.
Objective To study the relationship between placental pathologic changes and magnesium level in pregnant woman′s serum and umbilical vein of fetal growth restriction(FGR),thereby investigating the mechanism of FGR.Methods 32 pregnant women with FGR treated in our hospital from March 2011 to June 2013 were selected as the observation group,32 cases normal pregnant women were selected as the control group.The concentrations of magnesium were determined with automatic analyzing system,the placenta and fetal appendages of the two groups was observed with light microscope.Results The magnesium concentration of the observation group was significantly lower than that of the control group,the difference was significant(P0.05),the placenta pathologic changes of the observation group was significantly higher than that of the control group,the difference was significant( P0.05).Conclusion There is significant decrease in the magnesium levels of the pregnant woman′ s serum and umbilical vein of the FGR,so the blood circulatory resistant of fetal-placenta increases and the placental blood perfusion decreases,causing hypoxia and ischemia,so there is significant increase in placental pathologic changes.
Objective:This paper discusses the use of medical chitosan to the prevention of postoperative abdominal adhesions in Cesarean section.Methods:Using January 2006-December 2009 cesarean sections for a sample library,we select 500 cases as the observation group(application of medical chitosan) and 500 cases as the control group(no application of medical chitosan).Results:the total efficiency of anti-adhesion in the observation group was 95.37%,with the control group 78.70%.Evidently,The observation group was significantly higher(P <0.05).Conclusion:medical chitosan has a good post-operative anti-adhesion effect and should be introduced to cesarean section.
Objective To discuss the effect of C-reactive protein(CRP)levels in pregnant women with gestational diabetes meatus(GDM).Methods To select 96 GDM women with 75 grams oral slum tolerance test(OGTF)and 64 pregnant women with impaired gluccose tolerance(IGT)respectively,and choose 160 normal pmgnant women with normal slucose tolerance(NGT)randomly as control group,then observe their serum CRP level at the same time.Results The serum CRP level in GDM group was significantly higher than IGT group and control group (P<0.05).The sermn CRP level is positively related with pre-pregnancy body mass irdex(BMI),fasting bloodslope and fasting insulin,and the correlation coefficients are 0.338,0.163 and 0.283 respectively,and P values are 0.00001,0.0169 and 0.0003 respectively.Conclusion The blood sertlm C-reactive protein is closely related to GDM and involved in the pathogenesis of GDM.
Objective To explore the influence and treatment methods of hysteromyoma pregnancy. Method Through case-control study on 116 cases of hysteromyoma pregnancy and the same number cases of normal pregnan-cy in the same period, in order to observe the outcome of two groups. Results There is no significant difference in the matter of amount of bleeding when hysteromyoma pregnant women give birth to their children, no matter how oper-ation group, non-surgical group and control group(P > 0.05); but there is significant difference between non-surgical group and control group(P <0.05), and in the field of asphyxia neonatorum rate, there is no significant difference in all groups(P > 0.05). Conclusions The amount of bleeding in hysteromyoma pregnant women are more than vagi-nal delivery non-hysteromyoma women. It suggests that myomectomy won' t increase the amount of bleeding when doctors give the hysteromyoma women caesarean section at the same time. And the difficulty of surgery won' t signifi-cantly increase when compared to non-pregnancy and pregnancy.
Objective Inquire to the factors of preterm delivery occurrence;inquire to the affect on the decreasing mortality of the premature.infant by the nutritious treatment.Methods There are 5470 parturition in our hospital during 2005~2006,and 218 preterm deliveries among them(4.2%).Statistics the occur factors of 218 preterm delivery cases.38 cases between 28~34 weeks were randomly divided into two groups.19 cases in compare group simply were treated by stimulating fetal lung maturation,preventing from infection,restraining from womb contraction.Besides the previous measures,observation group were treated with 10% glucose 500 ml,co-vitamin 0.5 g,lipid emulsions 500 ml.All the neonates were calculated with Apgar grade system after one minute.Statistics with the Foxbase,use the Spss software for the χ2 test. Results The predominant cause of preterm delivery is premature rupture of membrane,83 cases occupied 38.2%;the next is pregnancy-induce hypertension syndrome(PIH),64 cases occupied 26.7%;21 cases with abnormal fetal position occupied 9.7%.There were 5 cases with Apgar mark 4 after one minute in the 19 cases-compared group,and 2 cases Apgar mark 4 in the observation group.There are remarkable difference between two groups(χ2=5.5,P0.05).Conclusion The predominant factor leading to preterm delivery is premature rupture of membrane,the next is PIH.It should be induced labor if it not be brought to bed when has a ahead rupture of membrane after 34 weeks pregnancy.Besides preventing from infection,stimulating fetal lung maturation,restraining from womb contraction.nutritious treatment should be added to the therapy on premature infant.