<正>急性出血坏死性胰腺炎是一种发病机理复杂和治疗棘手的危重急症。现已证实,胰腺凝血系统和纤溶系统功能改变参与了急性出血坏死性胰腺炎的病理生理过程[1]。但对启动凝血的关键因子-组织因子(tissue factor,TF)和组织因子途径抑制物(tissue factor pathway inhibitor,TFPI)以及调节纤溶功能的组织型纤溶酶原活化物(tissue-

Objective:To evaluate the clinical curative effect of integrated Chinese and western medicine for acute pancreatitis.Methods:40 patients were randomly divided into treatment group and control group,20 patients per group.The therapy of integrated Chinese and western medicine was used in treatment group,and the conventional western medicine therapy in control group.Results:The total effective rate was 95.0% in treatment group,while only 85.0% in control group(P0.05).Conclusion:The therapy integrated Chinese and western medicine is satisfactory for acute pancreatitis.

糖尿病是一种常见的内分泌疾病,其患病率和死亡率呈逐渐增高的趋势,高血糖还可以诱发冠心病和动脉粥样硬化[1].糖尿病发生的病因尚未完全明确,且无法根治,目前治疗的手段主要是控制血糖水平和防治并发症.因此,寻找安全有效的治疗糖尿病药物,是临床医学实践中迫切需要解决的课题.本研究探讨了桑地合剂有效部位对四氧嘧啶小鼠糖尿病的预防及治疗作用,现介绍如下.

缺血再灌注损伤(I/R)广泛存在于各种创伤与疾病中(如休克、失血、感染、多发性创伤、严重烧伤等)[1],可加重器官、组织的损伤,甚至危及生命.运用中药进行防治并研究其中药防治的机制,对组织器官移植修复和扩大中药应用范围均有着重要的理论意义和临床实践意义.川芎嗪(TMP)是从植物川芎中提取的化合物,近年来有研究发现其具有抗氧化、清除自由基、抗炎、抗渗出和改善微循环等作用[2],本研究旨在探讨TMP对肠缺血再灌注小肠损伤的保护作用,现介绍如下.