骨水泥植入综合征(BCIS)是指在手术中置入骨水泥时患者可能出现的一系列严重临床并发症,以顽固性低氧血症、血压骤降以及伴或不伴意识障碍为主要临床表现.BCIS多在骨水泥置入前后的时段发生,当前的主要治疗方法为及时使用血管活性药物、迅速补充血容量、足量的液体支持以及呼吸循环支持等.正确认识BCIS患者的各种危险因素,了解骨水泥的各种特性,明晰不良综合征报告等级,选择合适的麻醉方式是预防BCIS的重要前提.术中要注意细致轻柔操作,降低在打入假体过程中的髓腔压力,减少栓塞风险.此外,围手术期使用激素等药物也可以有效降低BCIS的风险.

威海市全力抓好全运会食品药品安全保障和兴奋剂治理工作.构筑了坚固的食品药品安全防线,为全运会威海赛区各项赛事的成功举办提供了坚实的保障.

<正>香丹注射液原名复方丹参注射液,是由丹参和降香组成的复方中药制剂。香丹注射液采用传统的水提醇沉法提取工艺。具有活血化瘀、养血安神、改善脏器微循环、保护缺氧组织、促进细胞再生等药理作用。临床上广泛应用于心绞痛、心肌梗死、脑血栓、脑栓塞等病症。

回顾性分析本市喹诺酮类药品不良反应(ADR)的发生情况,结果该药ADR发生频率偏高,但多为一般的ADR,涉及多个系统,以消化系统症状和皮肤损害最为多见。喹诺酮类药品用于治疗敏感菌所致的各种感染性疾病,仍为目前应用最广的一类抗感染药物,为减少喹诺酮类药物的不良反应,本文予以安全用药提示。

药品不良反应报告和监测工作是公众用药安全的保障,是上市后药品再评价的重要依据。基层医疗单位是药品不良反应(事件)频发的地方之一,其对药品不良反应报告和监测工作的重视程度及监测水平直接关系到患者用药的安全,是药品安全监管的重中之重。作为基层医疗单位应如何更好的开展药品不良反应报告和监测工作,如何建立和完善药品不良反应报告和监测体系,本文就这一问题进行探讨。

目的:对丰县2006年1月—11月药品不良反应报告类别填写和评价情况进行分析。方法:根据2006年1月—11月丰县食品药品监督管理局收集的423份报表,按报告类别、不良反应过程描述、呈报单位等进行统计分析。结果:正确判断并填写报告类别的占46.57%;不良反应描述全面的占72.58%。结论:丰县的药品不良反应报表质量有待提高。

Objective Describe the cardiovascular disturbance and prevention of the Polymethylmethacrylate(PMMA)bone cement in the joint-displacement operation to provide evidence for the safety evaluation and supervision.Method Analyze the domestic literatures by screening and classification.Result Bone cement in the joint-displacement operation easily lead the occurrence of cardiovascular complication as hypotension,arrhythmia,thrombus,lung-embolism and so on.Conclusion The literatures suggest that the risk exist in the clinical application and the surgeon use it cautiously.

Objective To give the related department some information and references by the result of the investi-gation of the cognition of Adverse Drug Reaction (ADR) of the masses. Method We have held a lecture that sub-ject medication security of the public and make time random sample, and then utilized excel table and manual filtrating to analyze 115 available questionaries. Result Conclusion Most of the people attending to the lecture have an inefficient concept and knowledge of ADR and other information. The masses hope the govern-ment increase the supervising forces of medication, assure the quality of the medicine, ban the illusive advertise-ment, publicize the safety of medicines information in time, and publicize some science reasonable medication knowledge frequently in order to give ensurance for using drug safely.

ADR Monitoring is a reassessment of the security of drugs came into market,which is the safeguard for public having medicines safely and reasonably and also plays an important role in the supervisal of the remedies.Our institution had investigated 103 medical staffs in Beichen hospital of Tianjin for finding out their relevant cognition of ADR,and analyzed the outcome of the investigation.We hope it could be the guidance and reference for relative departments to monitor medicines.

Adverse Drug Reaction(ADR) monitoring is the basic of the current drug's reevaluation,it is an impo- rtant part of the drug administration , it is the undertaking for the public to medicine safely and logically. Tianjin ADR center held the investigation of ADR cognization to the 132 medical staff who were from the 3 doublest-age hospitals in Dagang district. The statistical result should provide the department with gist and reference.