This paper focuses on the practical necessity of discipline-integrated PBL curriculum in cultivating clinical thinking ability of college students majoring in clinical medicine. Through the teaching process of group discussion of some real and complete cases, this paper explains in detail how to cultivate medical students' clinical thinking ability by discipline-integrated PBL curriculum, discusses the implementation of ideological and political education associated with clinical medicine by heuristic teaching from close touching with clinical case and implicitly infiltration of the socialist core values such as dedication and integrity, and elaborates the humanistic quality and psychological comfort levels of medical students by being close to clinical patients. After five years of teaching practice, the teaching effect of discipline-integrated PBL curriculum has been approved by the national clinical medicine professional certification experts and praised by students. We believes that the development of discipline integrated PBL curriculum in medical college can strengthen students' problem-based autonomous learning ability, significantly improve the two-way integration ability between basic medical courses and basic medicine, and significantly build students' clinical thinking and clinical decision-making ability.

1 案例资料 1.1案情摘要 1例委托父子亲缘关系的亲子鉴定案件,经无菌操作采集被鉴定人的指尖血少许. 1.2 DNA检验 取检材适量,依次采用DNA免提取扩增试剂盒PowerPlex(R)21检测系统(美国Promega公司)和GoldeneyeTM20AM检测系统(北京基点认知技术有限公司)进行复合PCR扩增,采用3130基因分析仪(美国Applied Biosystems公司)进行毛细管电泳,GeneMapper ID v3.2软件进行STR基因型分析.

医学免疫学理论抽象,知识体系严谨,医学生普遍认为难学.当前,CBL教学法因注重培养学生自主学习能力在医学教学中日益得到重视,并成为诸多医学类课程教学模式改革的重点内容.在医学免疫学教学中采取LBL与CBL相结合的教学模式,即在传统LBL教学法完成免疫学基本理论的基础上,引入基于CBL的翻转课堂教学法,确保了知识体系的完整性,同时激发学生对医学免疫学课程的学习兴趣,取得了较好的教学效果.