血脂异常是指由于脂肪代谢或转运异常,使血浆中1种或几种相关指标高于正常值,并认为血清高密度脂蛋白(HDL-C)降低也属于血脂代谢异常,而体重超重与血脂异常关系密切.2009年3月-2012年12月,我们采用针刺治疗体重超重及血脂异常80例,疗效满意.现分析报告如下.
目的 探讨血标本室温放置时间对血小板聚集的检验结果影响.方法 随机采集126例门诊体检健康志愿者静脉血标本,枸橼酸钠抗凝,离心分离富含血小板血浆(PRP)和贫血小板血浆(PPP),采用血浆比浊法,分别在不同的时间点测血小板聚集率.结果 标本室温放置1.5~24 h,10 μmol/L二磷酸腺苷(ADP)诱导血小板聚集率为(75.0±11.0)%~(28.7±11.5)%(F=244.84,P<0.01),0.5 mmol/L和1.0 mmol/L花生四烯酸(AA)诱导血小板聚集率分别为(83.2±8.7)%~(6.7±10.4)%(F=71.09,P<0.01),(84.6±8.5)%~(11.2±16.7)%(F=101.90,P<0.o1),都随时间延长而降低;pH值为(7.78±0.07)~(8.43±0.09),随时间延长而增大.结论 标本室温放置时间对ADP和AA诱导血小板聚集有明显的影响.10μmol/L ADP和0.5 mmol/L AA诱导血小板聚集,标本检测需在4h内完成,血小板聚集率随时间延长而降低可能与标本老化、pH过高有关.
目的 探讨医院综合重症监护病房(GICU)机械通气患者导管相关性血流感染(CRBSI)的病原菌特点及发生感染的相关危险因素.方法 选择2009年1月-2011年12月医院GICU182例机械通气患者为研究对象,对其导管相关性血流感染(CRBSI)的情况进行回顾性分析.结果 182例导管植入患者总置管天数5509 d,发生CRBSI25例,感染率为4.5‰;182份标本共分离出24株病原菌,其中革兰阴性杆菌12株,占50.0%,革兰阳性球菌8株,占33.3%,真菌4株,占16.7%,排名前4位病原菌依次为鲍氏不动杆菌、白色假丝酵母菌、金黄色葡萄球菌、阴沟肠杆菌,分别占29.2%、16.7%、12.5%、12.5%.结论 机械通气患者CRBSI以革兰阴性杆菌为主,与患者的病情危重程度、留置导管时间和医务人员缺乏较强的手卫生执行力有关.
Objective To explore the storage condition of arachidonic acid(AA) and adenosine diphosphate(ADP) for platelet aggregation.Method Venous blood sample of outpatient volunteers were collected(n=101) randomly and anticoagulaged sodium citrate,and platelet-rich plasma(PRP) and platelet-poor plasma was obtained by centrifuging the blood,then platelet aggregation rate of the plasma were detected with inducer of AA and ADP under the different storing conditions by plasma turbidimetry.Result When the inducer of AA and ADP were stored for 0 and 7 months,0 and 13 months in a-50℃ refrigeration respectively,the platelet aggregation rates were(47.9±37.5)% and(47.3±37.2)%,(66.2±15.7)% and(67.9±17.2)% respectively(P>0.05).When AA and ADP after thawing stored for 0 h and 24 h at 5℃,the rates were(47.8±38.8)% and(46.1±38.3)%,(67.1±25.8)% and(68.8±25.9)% respectively(P>0.05).Conclusion The inducers of AA and ADP store for 7 months and 13 months in a-50℃ refrigeration and AA and ADP after thawing store for 24 h at 5℃ respectively,the effect on the testing result of platelet aggregation is not significant.
OBJECTIVE To reduce the incidence of catheter-related bloodstream infections.METHODS A retrospective survey was performed to Group A by searching for discharged patients and completing a record sheet item by item.A targeted surveillance to Group B was performed,There were two full-time care nurses in charge of specific operations on central venous catheter by adopting a series of infection control measures,the data of the two groups were aggregated statistics,analyzed and judged,the infection rates were calculated and compared.RESULTS The catheter-related bloodstream infection rate of group A was 20.9‰,Group B took the method of targeted survey and implemented measures of infection control,the catheter-related bloodstream infection rate fell to 5.4 ‰,it was significantly different(P0.05).CONCLUSION In the comprehensive control measures,it is a very effective measure of setting professional nursing team on the whole process of quality management on central venous catheter tube and improving the technical level and execution of the doctors and nurses in the medical activities to reduce the catheter-related bloodstream infections.