Objective To investiget the effects of the standardized management treatment on the lung function in asthmatic children.Methods We built 61 medical records of asthmatic children in the community and divided them into two groups randomly.33 cases were in the standardized management group and the orther cases were in the control group(28 cases).In the management group,the patients and their parents were thaught with the knowledge about asthma and the medicines of asthma treatment.The escalation therapy was made for different states of the illness according to the GINA.And they were followed-up regularly and adjusted upgrade or downgrade the treatment on time.In non-management group,they were not followed-up,their treatment was determined on their parents.The clinical effects and the lung function of the two groups were compared after one year.Results The clinical effects of the standardized management group were better than those of the non-management group(χ~2=7.31,P<0.05).FEV_1 and PEF were risen and the differences were statistically significant in comparison with the non-management group after 1 year(P>0.05).And these indexes had no significant differences in the control group(P>0.05).The lung function of the standardized management group recovered better in 12 months than in 6 months.If asthmatic children were older than 9 years and the asthma duration more than sixty months,their lung function recoverd slowly.The frequencies of acute attack and the times going to hospital of the standardized management group were reduced obviously(P<0.05).Conclusion With the standardized management treatment of asthmatic children,the frequencies of acute attack and emergency department visit are reduced,the lung function is improved obviously.And the longer they are treated,the better their lung function recovers.The older and the longer asthma duration they are,the more slowly their lung function recovers.

Objective:To observe the effects of inhaled Combivent with budesonide in treatment of asthmatic disease in infants.Methods: One hundred and twenty asthmatic diseased infants were divided into two groups randomly.Sixty cases in the treatment group were treated with inhaled Combivent(1.25 mL) with budesonide(1 mL) based on the routine treatment,the control group(60 cases) was treated with inhaled salbutamol(0.25 mL) and hexadecadrol(5 mg) based on the routine treatment,once a day,for 5~7 days.Then we observed the improvement of clinical symptoms and signs,and compared the clinical effects.Results: The marked effect rate(81.7%) and the total effective rate(98.3%) of the treatment group were higher than those of the control group(60.0% and 88.3%)(P0.05).Conclusions: The clinical effects of inhaled Combivent with budesonide in treatment of asthmatic disease in infants were satisfactory.

Objective To investigate the current status of the treatment and management of asthmatic children,provide the basic data for the asthma control in the local area.Methods We performed an investigation by designing a questionnaire to investigate the asthmatic outpatients and their parents by professional doctors face to face.Results A total of 89 asthmatic children completed the questionnaire,80.9% of the patients chose ICS for therapy and only 29.2% of them with regular medication;38.2% of the patients treated with oral moutlukas,only 7.9% with desensitization and 11.2% with athletics.85.4% of the patients had lung function tests,Only 14.6% of all patients had twice or more lung function tests;95.5% of them had not learn the peak flowmeter and ACT(Asthma Control Test).Conclusion A few patients chose ICS for long-term regular therapy,few patients had monitored the disease process by lung function tests,almost no one used peak flowmeter and ACT(Asthma Control Test).We should reinforce the normalized treatment and management of asthmatic children in future,to improve their quality of life.

目的:探讨疱疹性咽峡炎的发病特点及干扰素高频振动雾化吸入联合利巴韦林喷剂治疗的临床疗效。方法:将我院收治的疱疹性咽峡炎患儿的临床资料进行分析。并随机分为观察组60例,对照组61例。结果:治疗组显效率63.3%,总有效率95%,对照组显效率34.4%,总有效率77%,两组比较差异有显著性(P<0.01)。治疗组退热时间及疱疹消失时间较对照组短,两组比较差异有显著性(P<0.01)。结论:发病季节以5月、6月及10月、11月较高,发病年龄1～3岁最多,占57.9%,3～7岁占26.2%,干扰素高频振动雾化吸入联合利巴韦林喷剂治疗疱疹性咽峡炎临床疗效明显,依从性好,可作为治疗疱疹性咽峡炎的首选药物。

Objective To evaluate the clinical efficacy ofmontelukast on asthma children.Methods A total of 48 children with asthma were randomly divided into two groups:montelukast group(group A) and Seretid group(group B).32 children in group A were treated with montelukast and Seretid for 3 month,and 16 children in group B were treated with only Seretid for 3 month.Results There was significant amelioration concerning the clinical efficacy rates and lung function efficacy rates,respectively,without serious cases in both groups and also no statistically significant difference between them(P0.05).Conclusion Montelukast is a effective drug in treating childrenwith asthma and possesses reliable efficacy and less adverse reaction.Montelukast associated with Seretid can be used to treat asthma effectively.

Objective:Clinical observation of the efficacy and safety of transdermal administration on bronchiolitis.Methods: One hundred and six children with bronchiolitis were divided into a treatment group(56 cases) and a control group(50 cases) at random.To observe the clinic effects,regular treatment of anti-infection and spraying was given to the control group,while the treatment group was administrated in addition transdermally,one time a day,for 3~5 days.Results: The resolving time of main symptoms and signs in the treatment group was shorter than that in the control group(P0.05).The total effective rate of the treatment group(98.2%) was significantly higher than that of the control group(86.0%)(P0.05).During the treatment there were few obvious adverse reactions.Conclusions: Regular treatment of bronchiolitis with transdermal administration as supplementary treatment is more effective than routine treatment.

<正>传染性单核细胞增多症(IM)是由EB病毒感染引起的疾病,婴儿原发性感染大多数无症状,但在儿童期、青年期约50%的原发感染均表现为IM[1]。我院2005年1月～2006年12月共收治IM病人30例,现分析如下:

咳嗽变异性哮喘 (CVA)临床上往往误诊为支气管炎或反复呼吸道感染而长期应用抗菌药物无效.现将 32例误诊病例分析如下.

现将我院1999年1月～2000年6月住院患儿,按美国心脏病学会1990年川崎病诊断标准[1]诊断的婴幼儿川崎病63例分析如下:

毛细支气管炎(毛支炎)是婴幼儿时期常见的下呼吸道感染性疾病,以咳嗽、喘憋、呼吸困难为临床症状,远期部分患儿存在气道高反应性[1].支气管扩张剂治疗是否有效存在分歧,现对毛支炎的婴儿喘乐宁溶液雾化吸入前后肺功能测定,报道如下.

鱼腥草注射液致肺水肿,国内尚无报道,我院出现一例,报道如下.病例:患儿,女,2岁9个月,体重13 kg,以咳嗽三天加重半天,发热2小时来院就诊.查体:体温39.1℃,急性热病容,神清合作,口唇红润;呼吸30次/分,无紫绀;咽部充血明显,双肺呼吸音粗,未闻干、湿罗音;心率118次/分,心律齐,心前区未闻杂音.血常规:白细胞总数7.8×109/L,分类中性粒细胞0.59,淋巴细胞0.41,考虑诊断急性上呼吸道感染.收入留察,给予5%GS100ml+鱼腥草注射液20ml静脉滴注.

1病例介绍 例1男,6个月零14 d.因腹泻20d,发热3 d入院.入院前20d无明显原因出现腹泻,黄色稀水便、蛋花汤样,4～5次/d,少许粘液,无脓血,不吐,无呛奶,入院前3 d出现发热,体温38.3℃,无寒战抽搐,入院前1d其家长发现患儿面色差,呕吐1次,非喷射状,病期奶量减少.母乳喂养至今未添加辅食.入院查体:体温38.5℃、呼吸50次/min、脉搏180次/min,呼吸急促,轻度脱水貌,胸腹部可见弥漫性红色粟粒疹,压之退色,咽部充血,心率180次/min,律齐,心音低钝,腹软无压痛,肝肋下2.5 cm,剑突下1.5 cm,肠鸣音活跃,四肢活动正常,指(趾)端无硬肿.辅助检查:心电图示心率180次/min、TⅢ倒置、Tavf平坦.