Objective to analyze the risk factors of coronary heart disease. Methods 34 patients with coronary heart disease admitted in our hospital were randomly selected from february 2011 to february 2013. according to the clinical characteristics and coronary angiography in patients with coronary heart disease, risk factors were analyzed. Results of 34 cases selected, 13 patients performed with body mass index severely exceeding the standard, 17 cases with serious smoking history, 9 cases with hypertension, 6 patients with diabetes mellitus. Conclusion overweight and obesity are the main potential risk factors for coronary heart disease and hypertension is an independent factor for coronary heart disease, and coronary heart disease risk is associated with blood glucose levels. Understanding the risk factors for coronary heart disease and atherosclerosis and given therapeutic intervention for risk factors, especially has very important signiifcance for effective prevention and treatment of dyslipidemia.
目的 探讨高通量血液透析(HFHD)联合血液灌流(HP)对血清甲状旁腺素(PTH)和血清白蛋白(ALB)的影响.方法 选取30例维持性低通量血液透析合并继发性甲状旁腺功能亢进的患者,随机分为LFHD和HFHD+HP两组,每组各15例,LFHD组予常规低通量血液透析,每周三次;HFHD+HP组予每两周5次常规低通量透析,每两周一次HFHD+HP治疗,于0个月、12个月分别检测两组的血清Ca2+、P3+、iPTH、ALB的浓度.结果 治疗12个月后,两组比较发现:HFHD+HP组的iPTH明显下降,ALB明显升高(P＜0.05),LFHD组的iPTH、ALB无明显变化(P＞0.05);两组治疗后比较,HFHD+HP组的P3+,hs-CRP明显降低,差异有统计学意义(P＜0.05),Ca2+差异无统计学意义.结论 HFHD联合HP治疗能有效清除MHD患者的PTH,长期应用可以升高血清ALB,改善营养状态.
目的研究诺和灵30R和诺和锐30在2型糖尿病合并糖尿病肾病(DN)维持性血液透析病人中的降糖效果及安全性。方法采用自身前后对照,对26例DN维持性血液透析病人先后应用诺和灵30R和诺和锐30进行对比,分别监测非透析日空腹血糖、餐后2 h血糖、糖化血红蛋白(HbA1c)、透析日透析前血糖、透析中2 h血糖等指标并进行统计学分析。结果应用诺和锐30后非透析日餐后2 h血糖、透析前血糖、透析结束时血糖有明显改善(P<0.05)。结论诺和锐30的疗效及安全性优于诺和灵30R。
Objective To investigate the effect of high-flux hemodialysis with ultrapure dialysate on microinflammation state in maintenance hemodialysis patients.Methods Sixty maintenance hemodialysis(MHD) patients were randomly assigned,including 30 high-flux dialysis group patients and 30 low-flux hemodialysis group patients.They were used low-flux dialyzer and common dialysate before the trial.During the 12-month study period,high-sensitivity C reactive protein(hsCRP),serum albumin(ALB),hemoglobin(HGB) and β2 microglobulin(β2-MG) levels were detected every 6 months.Results In the high-flux group the plasma hsCRP and β2-MG significantly decreased,ALB and HGB obviously increased(P 0.05).In the low-flux group these parameters had no obvious changes.Conclusion Our study demonstrates that high-flux hemodialysis with ultrapure dialysate could efficiently decrease hsCRP,lighten microinflammation state of maintenance hemodialysis patients and improve malnutrition and anemia.
目的探讨连续性肾脏替代治疗(CRRT)联合血液灌流治疗中毒合并多器官功能障碍综合征的临床疗效。方法对7例中毒并多器官功能障碍的患者给予CRRT联合血液灌流并病因治疗,观察治疗前后患者的各项生化指标。结果 5例患者肾功能恢复正常,痊愈出院。2例患者因多器官功能衰竭死亡。结论对于中毒并多器官功能障应尽早进行持续性血液净化治疗,从而改善患者的预后,缩短住院时间。
