糖尿病性视网膜病变(DR)是最常见的视网膜血管病,为50岁以上人群主要致盲眼病之一.本病早期无自觉症状,病变发展到黄斑后出现不同程度的视力减退.近几年来,笔者采用自拟滋阴活血方治疗糖尿病性视网膜病变31例,疗效显著.现总报道下.

[Objective] To introduce the clinical experience of treating thyroid adenoma by Shi Kuijun.[Methods] Through copying prescription with the teacher and carding records,combined with studying on Chinese literature by Shi Kuijun,sum up Shi Kuijun insights for the etiology,pathogenesis,disease location,pathological diagnosis and the theory of therapeutic principles and methods of thyroid adenoma.[Results] Shi Kuijun puts forward the treatment of thyroid adenoma when treating from the liver,treating the liver goes first,supplemented by reducing phlegm and resolving masses and promoting blood circulation.[Conclusions ]The treatment of thyroid adenoma form liver has achieved satisfactory effect in clinical practice and provides the significant guid ance in the clinical practice.

目的:观察滋阴活血方对糖尿病大鼠视网膜瘦素表达的影响.方法:SD大鼠尾静脉注射4.5％链脲佐菌素诱导糖尿病模型.实验分为正常组、模型对照组、多贝斯治疗组、滋阴活血方组,灌胃治疗6周.取各组大鼠眼球组织,分别用免疫组织化学染色、免疫印迹方法检测各组大鼠眼球视网膜瘦素的表达.结果:免疫组化检测结果显示:糖尿病模型组大鼠视网膜各层瘦素染色程度较正常组明显增加为中度(++),多贝斯治疗组和滋阴活血方治疗组的染色程度则为轻度(+).免疫印迹结果显示:糖尿病大鼠视网膜瘦素相对表达量较正常组明显升高(P＜0.01),而多贝斯对照组、滋阴活血方治疗组的表达量较模型对照组明显下降(P＜0.01).结论:滋阴活血方可降低糖尿病大鼠视网膜瘦素表达,对糖尿病视网膜病变起到一定的改善作用.

"更年合剂"为我院根据验方研制而成的医院制剂,用于治疗妇女绝经期前后的更年期综合征.经长期的临床观察显示,该制剂具有较好的临床疗效,现报道如下.