Objective: To investigate the candidal infection status in puerperas in Lanzhou,and the candidal transmission from mothers to their newborn infants.Methods: Vaginal fluid and saliva samples from 104 puerperas,as well as 104 saliva samples from their newborn infants were collected.The candida species were cultured,isolated and identified using CHROMagar media.Further identification was done using molecular biological method.Results: In 81 of 312 specimens(104×2 from mothers and 104 from infants),candida species were found.39.42%(41 cases) was observed in the vaginal fluid and 33.65%(35 cases) was in saliva of puerperas respectively,and 21.15%(22 cases) in both vagina and oral cavity.4.81%(5 cases) was found in oral cavities of newborn infants.The distribution of candida species were 53 Candida albicans,33 Candida glabrata,2 Candida krusei and 1 Candida tropical.In 2 pairs of mother-infant,the same genotype of Candida ablicans was identified using PCR method.Conclusion: The Candida detection rate of newborn infants and transmission rate from mothers to their neonates in Lanzhou are higher than that reported in other areas.The colonization of candida in newborn infants is relevant to both horizontal and vertical transmission.It can decrease the possibility of Candidal infection in newborn infants by controlling the Candidal transmission in hospital and preventing the infection in pregnant women.

选择甘肃产黄芪为原料,制成水浸出液,研究其对口腔常见致龋菌的抑制效果,并与国外致龋菌抑菌产品（MI）进行比较。以变形链球菌、乳酸杆菌为实验菌株,用选择性培养基进行液体培养,在培养基中添加不等量的药物,测培养24h后菌液的A值、pH值;用SPSS13.0对数据进行统计分析。黄芪浸出液对变形链球菌、乳酸杆菌的生长、产酸均有抑制效果,抗菌效果与MI相当。

作者选择患慢性根尖周炎儿童214例,共256颗患牙,用Vitapex糊剂行一次乳牙根管治疗术,现报告如下.

目的观察复方五倍子治疗口腔溃疡的疗效.方法将口腔溃疡患者127例随机分成两组,实验组用复方五倍子治疗,对照组以维生素B2和维生素C联合治疗.结果两组疗效经统计学检验P＜0.05,差异有显著性.结论复方五倍子治疗口腔溃疡疗效显著,中西医结合治疗口腔溃疡不失为一种行之有效的方法.

目的通过对137例口腔白斑的发病原因、临床表现、病理变化及病损的转归等方面的追踪观察与临床分析,以便为口腔白斑的防治及防止其癌变积累临床经验.方法对137例口腔白斑进行临床分型,所有病例均做活检,分别采取驱除机械刺激及戒烟,口服维生素A并局部涂擦5%5-FU,手术切除等方法进行治疗.结果口腔白斑少数发生癌变,口腔白斑癌变倾向与临床分型、病损部位有较为密切的关系,上皮异常增生是口腔白斑癌变过程中一个关键阶段,本文采取的治疗方法取得了一定的临床效果.结论目前口腔白斑是国际公认的癌前病变,其发病原因、作用机制等仍不明确,尚无理想的药物或疗法,本文在此方面的探索对口腔白斑的防治及防止其癌变仍有一定的积极意义.

Objective: The purposes were to analyse the causes and explore the mend methods of fracture of the upper complete denture base. Methods: 51 cases were clinically analysed and were repaired by the base replacement technigue. Results: 88.24% of breaking was caused by biting. The breaking lines were largely located in the front part of palatal base and were longitudinal(97.78%). Using base replacement technigue, the results of mend were satisfying. Conclusion: In order to avoid the fracture of upper complete denture, it is necessary to increase resistance on stress concentration area on the front part of the base, reduce the weak effect of notch of frenum labiorum, and keep the occlussion balance.

作者对临床52例中老年无牙颌患者戴全口义齿后的适应性、影响适应性的自身因素及两者之间的关系进行了临床研究.结果表明:随着患者年龄的增长,戴义齿的适应能力逐渐下降;有修复史(包括PRDs)的患者对义齿的适应能力强;文化水平越高,对义齿的适应能力越强;性别对义齿的适应性无影响.提示:医师在修复义齿前,应对患者的自身条件做出评估,并做出相应的解释措施.