Background: There is evidence supporting electroacupuncture (EA) for the treatment of major depressive disorder (MDD), but its characteristics have not been well investigated. Objective: To investigate the effectiveness and characteristics of EA in MDD. Methods: 60 subjects were enrolled—35 in the EA group and 25 in the selective serotonin reuptake inhibitor (SSRI) group based on their preferences—in an 8-week non-randomised controlled clinical trial. The 24-item Hamilton depression rating scale (HAMD-24) and clinical global impression (CGI) were adopted for clinical assessment. The Columbia suicide severity rating scale and adverse event form were used to measure safety and tolerability. The characteristics of EA and SSRIs were compared by analysing seven factors of the HAMD-24. Results: There was no significant difference between the two groups in terms of HAMD-24 response rate after intervention (P>0.05). Patients treated with EA demonstrated a significant reduction in CGI scores (P<0.05) with fewer adverse events compared with SSRIs (P<0.01). Although HAMD-24 factor analysis showed both EA and SSRIs could improve factor scores in cognitive impairment, diurnal variation, retardation, sleep disturbance, anxiety/somatisation and feelings of despair, EA showed greater improvement in anxiety/somatisation and feelings of despair than SSRIs (P<0.05). Conclusions: There was no significant difference between EA and SSRIs in the treatment of MDD with respect to our primary outcome. However, as a potential therapy for MDD, EA appeared to result in greater symptom improvement than SSRI treatment with respect to anxiety/somatisation and feelings of despair. The results of this secondary analysis should be interpreted cautiously given the inherent issues of multiple testing.
Objectives: To explore the effects of acupuncture (manual acupuncture or electroacupuncture) combined with SSRIs for moderate to severe depression improving major clinical symptoms and life quality of the patients on secondary outcomes. Design: Pragmatic, parallel, randomized controlled trial. Setting: 6 hospitals in China. Interventions: 6 weeks of manual acupuncture (MA) + selective serotonin reuptake inhibitors (SSRIs), electro-acupuncture (EA) + SSRIs, and SSRIs alone. Main outcome measures: The primary outcome was response rate of 17-item Hamilton Depression Scale (HAMD- 17) total score at 6th week. The secondary outcomes reported in this analysis were HAMD-17 factor scores at 1st, 2nd, 4th, 6th, 10th week and WHO Quality of Life-BREF (WHOQOL-BREF) scores at 6th week. Results: 477 patients were randomly assigned into MA + SSRIs (n = 161), EA + SSRIs (n = 160), or SSRIs alone (n = 156) groups. For HAMD-17 (at 6th week), the MA + SSRIs group was significantly better than the SSRIs alone group in retardation factor (p = 0.008), while the EA + SSRIs group was significantly better than the SSRIs alone group in anxiety/somatization factor (p < 0.001) and sleep disturbance factor (p = 0.002). For WHOQOL-BREF (at 6th week), the EA + SSRIs group, compared with the SSRIs alone group, produced a more significant improvement in the overall quality of life, general health, physical health, and psychological health (p < 0.05). While, the MA + SSRIs group, compared to the SSRIs alone group, showed significant advantage only in psychological health (p = 0.023). Conclusions: Either MA or EA combined SSRIs treatment could improve symptoms and quality of life for patients with moderate to severe depression. The main limitation of this trial was not using a sham control therefore the placebo effect could not be excluded.
Background Individuals with sub-syndromal depression (SSD) are at increased risk of incident depressive disorders; however, the ideal therapeutic approach to SSD remains unknown. Objective To evaluate the effects of electroacupuncture (EA) and cognitive behavioural therapy (CBT), alone or in combination, on depressive symptoms. Methods Undergraduate students with SSD were recruited and allocated to one of four groups based on their preferences: EA (n=6), CBT (n=10), EA+CBT (n=6), and untreated control (n=11) groups. Six weeks of treatment were provided in the first three groups. Clinical outcomes were measured using the 17-item Hamilton Depression (HAMD-17) rating scale, Center for Epidemiologic Depression (CES-D) scale, WHO Quality of Life-Brief version (WHOQOL-BREF) questionnaire, and clinical remission rate. Results All 33 subjects were included in an intent-to-treat analysis. Statistically significant improvements in HAMD-17, CES-D, and WHOQOL-BREF scores and a higher remission rate were found in the EA, CBT, and EA+CBT intervention groups compared with the control group (all p<0.05). No significant differences were found between the three intervention groups. HAMD-17 factor score analysis revealed that EA reduced sleep disturbance scores more than CBT or EA+CBT (p<0.05), and CBT reduced retardation scores more than EA (p<0.01). EA+CBT reduced anxiety/somatisation scores more than EA or CBT (p<0.05) and retardation scores more than EA (p<0.05). Conclusions Early intervention may alleviate depressive symptoms in SSD. EA and CBT may have differential effects on certain symptoms. Combination therapy targeting both physical and psychological symptoms may represent an ideal strategy for SSD intervention. However, randomised trials with larger sample sizes are needed. Trial Registration Number ChiCTR-TRC-10000889; Results.
Reinforced concrete slabs are among the most common structural elements. In spite of the large number of slabs designed and built, the effect of their details on their behavior under impact loads are not always appreciated or properly taken into account. Based on finite element theory, the impact resistance performance of reinforced concrete slab was studied by utilizing LS-DYNA software. In the study, the material nonlinear and contact nonlinear were considered, and the parameterized modeling is established. The results show that the thicker the slab is, the larger the impact resistance of the slab is. The research of this paper provides some foundations and suggestions for the design of reinforced concrete slabs.
目的:探索理性情绪行为疗法(REBT)对有抑郁症状的大学生心理干预的有效性.方法:采用方便取样法抽取北京市大学生1 270名,经CES-D筛出大学生242名.HAMD(HAMD>7分,≤17分)进一步筛选出大学生87名,有24名签署知情书并入组,将其分两组,各12人.干预程序:建立心理支持联盟;认识ABC及其关系;自我示教法;与不合理信念辩论;寻找证据法;良性事件记录法;行动计划法;巩固与退角色;每次配以家庭作业.在团体干预前、8周干预结束后施测CES-D、HAMD.结果:大学生CES-D测量干预前分数为(27.38±5.50)分,干预后为(11.00±7.67)分(P<0.05);HAMD干预前分数为(9.38±1.92)分,干预后为(4.25±2.71)分(P<0.05).结论:使用REBT对大学生抑郁症症状,特别是对具有认知障碍和躯体症状人群的干预有效.
Subthreshold depression (StD) is a highly prevalent condition associated with increased service utilization and social morbidity. Nevertheless, due to limitations in current diagnostic systems that set the boundary for major depressive disorder (MDD), very few brain imaging studies on the neurobiology of StD have been carried out, and its underlying neurobiological mechanism remains unclear. In recent years, accumulating evidence suggests that the disruption of the default mode network (DMN), a network involved in self-referential processing, affective cognition, and emotion regulation, is involved in major depressive disorder. Using independent component analysis, we investigated resting-state default mode network (DMN) functional connectivity (FC) changes in two cohorts of StD patients with different age ranges (young and middle-aged, n = 57) as well as matched controls (n = 79). We found significant FC increase between the DMN and ventral striatum (key region in the reward network), in both cohorts of StD patients in comparison with controls. In addition, we also found the FC between the DMN and ventral striatum was positively and significantly associated with scores on the Center for Epidemiologic Studies Depression Scale (CES-D), a measurement of depressive symptomatology. We speculate that this enhanced FC between the DMN and the ventral striatum may reflect a self-compensation to ameliorate the lowered reward function.
<span id="ChDivSummary" name="ChDivSummary" class="abstract-text">目的:探讨大学生的抑郁状态、生存质量与人格特质的关系,为保障大学生的心理健康提供帮助。方法:选取大学生2270人,采用流调中心用抑郁自评量表(CES-D)测量抑郁状态(将CES-D评分≥16分者归于抑郁组,<16分者归于非抑郁组),世界卫生组织生存质量简表(WHOQOL-BREF)评价主观生活质量,大五人格量表简化版(NEO-FFI)评价人格特质(神经质、外向性、开明性、随和性和责任心)。以CES-D总评分、4个维度评分以及WHOQOL-BREF量表总评、4领域评分为因变量,五种人格特质为自变量做多重线性回归,探讨人格特质对受试者抑郁状态和主观生存质量的预测作用。结果:受试大学生CES-D平均分为(11.4±8.8),抑郁组(n=474)生存质量总评、健康总评及WHOQOL-BREF各领域评分均低于非抑郁组(n=1416)(均P<0.001)。同非抑郁组相比,抑郁组的神经质评分较高[(38.9±6.9)vs(28.9±6.3)],外向性、开明性、随和性和责任心评分均较低[(34.3±6.1)vs(41.2±6.2),(39.6±6.5)vs(40.6±5.5),(41.5±5.3)vs(45.3±4.6),(38.6±6.7)vs(43.7±6.3)],均P<0.05。多重线性回归分析显示,大五人格量表中,神经质评分与CES-D量表总评分和4个维度评分均正向关联(β=0.49、0.29、0.52、0.33、0.30),与WHOQOL-BREF总评分和4领域评分均为负向关联(β=-0.10、-0.08、-0.13、-0.18、-0.12、-0.10);结论:本研究提示大学生的情绪状态和主观生存质量与人格特质中的神经质存在相关性,神经质程度高的个体易产生负面情绪,主观生存质量评价降低。</span>
Objective To investigate life events of undergraduates,to explore their predictive effect on depressive status,and to give advice for maintenance of mental health of undergraduates.Methods By cluster sampling,2 270 undergraduates were recruited to receive questionnaire surveys.Center for Epidemiologic Studies Depression Scale (CES-D) was used to measure depressive status (CES-D ≥ 16 was defined as depressive status while CES-D< 16 was defined as non-depressive status),life event scale(LES) was applied to assess life events of undergraduates.Results The mean score of LES was (8.71± 11.00) and the mean score of CES-D was (11.43± 8.80),the occurrence of depressive status was 25%." High pressure from study and work" (55%)," being misunderstood or blamed unjustly" (36%) and "Big change on life schedule" (28%) were rated as the first three highest occurrence life events.Stepwise regression analysis demonstrated that scores of negative study and work events were positively associated with CES-D scores and scores of the four dimensions of CES-D scale(β=0.24,0.15,0.22,0.22,0.14).Scores of negative family events were positively associated with CES-D scores and scores of positive and depressed affect (β=0.07,0.09,0.08).Scores of negative social interaction were positively associated with scores of interpersonal problems (β=0.06).Students in depressive status group (n=467) exhibited higher scores on negative family events,negative work and study events and negative social interaction than those in nondepressive status group (n=1 386) ((3.40±5.28) vs (2.01±4.32),(3.76±4.25) vs (2.03±3.13),(2.05±3.30) vs (1.32±2.74),P<0.01).Conclusion It suggests that undergraduates present favorable mental health condition.Study and work events are primary life events of undergraduates.Pressure from study and work and social interaction can affect their mental health.
目的 探究北京、内蒙地区大学生的情绪状态及生存质量,以期找到不同地区大学生的共性及差异性,为保障大学生的心理健康提供帮助.方法 采用流调中心用抑郁自评量表(CES-D)测量抑郁状态(将CES-D评分≥16分者归于抑郁组,<16分者归于非抑郁组)、世界卫生组织生存质量简表(WHOQOL-BREF)评价主观生活质量,对2 270名北京、内蒙古大学生进行抽样问卷调查获得有效问卷1 886份,其中北京1 109份,内蒙古877份.结果 两地大学生群体内比较结果显示:北京大学生抑郁组在生存质量总评、健康总评及生理、心理、社会关系和环境4个领域的评分均低于非抑郁组大学生(P<0.01);而内蒙古大学生抑郁组在心理、社会关系和环境领域中评分低于非抑郁组大学生(P<0.05).两地大学生群体间比较结果显示,北京大学生CES-D评分低于内蒙古大学生[(11.16±9.00)vs(11.68±8.51)],P<0.05;北京大学生在躯体症状与活动迟滞和人际活动维度上评分低于内蒙古大学生,[(3.48±2.96) vs(4.02±2.84)],[(0.39±0.90) vs (056±1.11)],均P<0.05;北京大学生在健康总评和生理领域评分低于内蒙古大学生[(3.44±0.89) vs (3.62±0.86)][(14.55±2.11) vs(14.76±2.10)],在环境领域评分高于内蒙古大学生[(13.38±2.08)vs(13.16±2.16)],均P<0.05.结论 两地大学生情绪状态良好,生存质量主观评价较高.内蒙古大学生抑郁评分偏高,躯体症状及活动迟滞明显,人际活动较少,对周围环境满意度偏低,对自我健康情况满意度较高.
Purpose: To evaluate therapeutic effects of early interventions and compare advantages of Electro-acupuncture (EA), Cognitive Behavior Therapy (CBT) and their combination therapy in ameliorating depressive symptoms. Methods: 33 subjects in depressive status, included via Hamilton Depression Rating Scale-17 (HDRS-17) and Mini International Neuropsychiatric Interview (MINI), were assigned into 4 groups depending on their intentions, EA group (6 cases), CBT group (10 cases), combination of EA and CBT group (6 cases) and observation group (11 cases). Intention To Treat (ITT) analysis and Per Protocol (PP) analysis were employed to evaluate primary outcome measures (clinical response rate based on rate of HDRS-17 score changes, clinical remission defined as an endpoint HDRS-17 score 0.05). Conclusion: Early interventions could alleviate depressive symptoms. EA improve somatic symptoms and insomnia while CBT favors mitigating cognition and mood dysfunction. The combination therapy targeting both physical and psychological symptoms might be an ideal strategy for depressive status intervention. Contact: Tianwei Guo, guotianwei tcm@126.com
This consensus statement is organized into six parts: 1) Definitions: cancer-related depressed mood state is defined as a group of depressive symptoms, rather than major depressive disorder. Thus, “cancer-related depression” or “depressed mood state” is introduced as standard terminology and associated with the Chinese medicine concept of “yu zheng” (depression syndrome). 2) Pathogenesis: factors including psychological stress, cancer pain, cancer fatigue, sleep disorders, surgery trauma, chemotherapy, and radiation therapy are strongly associated with cancer-related depressed mood state. Crucial elements of pathogenesis are cancer caused by depression, depression caused by cancer, and the concurrence of phlegm, dampness, and stasis from constrained liver-qi and spleen deficiency. 3) Symptoms: these include core symptoms, psychological symptoms, and somatic symptoms. Depressed mood and loss of interest are the main criteria for diagnosis. 4) Clinical evaluation: based on the Mini-International Neuropsychiatric Interview and a numeric rating scale, and taking mood changes during cancer diagnosis and treatment into consideration, a questionnaire can be drafted to distinguish between major depressive disorder and cancer-related depression. The aim is to assist oncology clinicians to identify, treat, and refer patients with cancer-related depression. 5) Diagnosis: diagnosis should be based on the Chinese Classification for Mental Disorders (CCMD-3), taking patients' mood changes during diagnosis and treatment into consideration. 6) Treatment: treatments for cancer-related depression must be performed concurrently with cancer treatment. For mild depression, non-pharmacologic comprehensive therapies, including psychological intervention, music therapy, patient education, physical activity, and acupuncture, are recommended; for moderate depression, classical Chinese herbal formulas based on syndrome pattern differentiation combined with antidepressants are suggested; for severe depressive symptoms that have progressed to major depressive disorder, patients should be referred to a psychiatric clinician for specialized care.
The clinical effect of electroacupuncture on depression is widely recognized. However, the signal transduction pathways and target proteins involved remain unclear. In the present study, rat models of chronic restraint stress were used to explore the mechanism by which electroacupuncture alleviates depression. Rats were randomly divided into control, model, and electroacupuncture groups. Chronic restraint stress was induced in the model and electroacupuncture groups by restraining rats for 28 days. In the electroacupuncture group, electroacupuncture pretreatment at Baihui (GV20) and Yintang (GV29) acupoints was performed daily (1 mA, 2 Hz, discontinuous wave, 20 minutes) prior to restraint for 28 days. Open field tests and body weight measurements were carried out to evaluate the depressive symptoms at specific time points. On day 28, the crossing number, rearing number, and body weights of the model group were significantly lower than those in the control group. Behavior test results indicated that rat models of depressive-like symptoms were successfully established by chronic restraint stress combined with solitary raising. On day 28, an isobaric tag for a relative and absolute quantitation-based quantitative proteomic approach was performed to identify differentially expressed proteins in hippocampal samples obtained from the model and electroacupuncture groups. The potential function of these differential proteins was predicted through the use of the Cluster of Orthologous Groups of proteins (COG) database. Twenty-seven differential proteins (uncharacteristic proteins expected) were selected from the model and electroacupuncture groups. In addition to unknown protein functions, COG are mainly concentrated in general prediction function, mechanism of signal transduction, amino acid transport and metabolism groups. This suggests that electroacupuncture improved depressive-like symptoms by regulating differential proteins, and most of these related proteins exist in nerve cells.
Objective To study the effect of acupuncture on alleviating side effect of paroxetine and improving quality of life in treating mild or moderate depression.Methods A randomized controlled clinical trial was performed.Inpatients and outpatients with depression (n =72) were randomly divided into electro-acupuncture (EA) and paroxetine group (group A,n =23),manual acupuncture and paroxetine group (group B,n=32) and paroxetine alone group (group C,n=17).Outcome was assessed with Hamilton depression scale(HAMD) at baseline and weeks 1,2,4,and 6.Side effects were assessed with rating scale for side effects(SERS) at baseline and weeks 2,4,and 6.The world health organization quality of life(WHOQOL-BREF) scale on quality of life was given at baseline and week 6.Results There were no differences among the three groups at baseline (P>0.05).Accorling to the HAMD scores,significant difference was seen between group A and C (Z =3.2242,P<0.05),and also between group B and C(Z =L6224,P<0.05).No significant difference was found between the two acupuncture groups (P>0.05).SERS scores in the acupuncture groups were significantly lower than those for paroxetine alone at weeks 2(F=5.48,P<0.05),week 4(F=7.70,P<0.05),and week 6 (F=7.73,P<0.05).WHOQOL-BREF scores were significantly higher in the two acupuncture groups than those in the paroxetine only group in five periods,which were total subjective feelings regarding quality of life (F=4.19,P<0.05),health sensation(F=4.49,P<0.05),physical condition(F=12.46,P<0.05),psychology condition (F=10.52,P<0.05) and circumstances (F=5.36,P<0.05).Conclusion Acupuncture can alleviate side effect of paroxetine and improve quality of life in treating mild or moderate depression.
[Objective]To analyze the emotion status and quality of life among different occupational grups in Beijing,find the commonness and differences,and give advices for the maintenance of mental health and living quality. [Methods]State owned enterprise( SOE) workers,company employees and migrant workers were randomly sampled to receive questionnaire survey consisted of Center for Epidemiologic Studies-Depression( CES-D),World Health Organization Quality of Life-BREF( WHOQOL-BREF) and personal information form. [Results〗]Mean scores of CES-D in SOE workers,company employees and migrant workers were15. 5 ± 9. 4,11. 8 ± 8. 3,8. 3 ± 7. 4 respectively,and the difference was statistically significant( F = 65. 91,P 0. 01). Quality of life scores of respondents in depression group( CES-D≥16) were remarkably lower than those in non-depression group among all three groups( t =-2. 62 ~-10. 70,P 0. 01). Migrant workers exhibited higher scores than SOE workers and company employees in overall quality of life,general health and all domain scores of WHOQOL-BREF,SOE workers showed lowest scores in all aspects. The differences were all statistically significant( F = 33. 33 ~ 2365. 64,P 0. 01). [Conclusion]Migrant workers and company employees show favorable emotion status and quality of life,while SOE workers suffer from a higher rate of depressive state and poor assessment of quality of life. Depressive emotions exert negative effects on quality of life in occupational groups. Relevant departments should take corresponding measures based on varied characteristics of occupational groups.
The Journal of Alternative and Complementary MedicineVol. 20, No. 5 AbstractNo accessPublished Online: 7 May 2014 Share on Effect of Acupuncture on Expression of CREB and p-CREB in Hippocampus and Prefrontal Cortex of Depression RatsAuthors: Lan Sun, Jia Liang, Tianwei Guo, Zhuo Guo, Xinjing Yang, Sihan Wang, Linlin Sun, Qingyi Lu, and Jie ChenAuthors Info & AffiliationsPublication: The Journal of Alternative and Complementary MedicineVolume 20, Issue Number 5https://doi.org/10.1089/acm.2014.5222.abstract Permissions & CitationsPermissionsDownload CitationsTrack CitationsAdd to favorites Get Access
Objective To analyze correlations between personality traits,life events and depressive symptoms based on structural equation model and to identify risky factors of depressive symptoms.Methods Using stratified random cluster sampling method,industrial workers recruited from Shougang Qianan corporation received questionnaire survey consisted of LES,NEO-FFI and CES-D.Maximum likelihood method was applied to calculate parameters of structural equation model,then the final model was confirmed based on modification indices.Results Depressive symptom(CES-D ≥ 16) prevalence was 41.05% among industrial workers in current study.Neuroticism,extraversion,agreeableness and negative life events were significantly predictive to depressive symptoms (r=0.356,-0.304,-0.135,0.227).Positive and negative life events,neuroticism and extraversion,extraversion and conscientiousness,neuroticism and agreeableness presented high correlation,with coefficients 0.614,-0.469,0.432 and 0.402 respectively.The regression weight of affective symptoms,somatic symptoms and interpersonal relationship in measurement model were 0.779,0.678,0.464.Conclusion The onset of depressive symptoms among industrial workers is remarkably related to neuroticism,extraversion,agreeableness and negative life events.Certain measures are supposed to be conducted for mental nursing and intervention in order to strengthen depression prevention.
The Journal of Alternative and Complementary MedicineVol. 20, No. 5 OtherPsychological Intervention of Symptoms for Depression in College Students with REBT: Implementation in Design and PracticeJie Chen, Wenyue Zhang, Qian Wu, Xinjing Yang, Shuang Jiao, Xueqin Yang, Xuehong Ma, Sihan Wang, Zhuo Guo, Tianwei Guo, Wenhao Ma, Lan Sun, and Qinyi LuJie ChenSearch for more papers by this author, Wenyue ZhangSearch for more papers by this author, Qian WuSearch for more papers by this author, Xinjing YangSearch for more papers by this author, Shuang JiaoSearch for more papers by this author, Xueqin YangSearch for more papers by this author, Xuehong MaSearch for more papers by this author, Sihan WangSearch for more papers by this author, Zhuo GuoSearch for more papers by this author, Tianwei GuoSearch for more papers by this author, Wenhao MaSearch for more papers by this author, Lan SunSearch for more papers by this author, and Qinyi LuSearch for more papers by this authorPublished Online:7 May 2014https://doi.org/10.1089/acm.2014.5394.abstractAboutSectionsView articleView Full TextPDF/EPUB Permissions & CitationsPermissionsDownload CitationsTrack CitationsAdd to favorites Back To Publication ShareShare onFacebookTwitterLinked InRedditEmail View article"Psychological Intervention of Symptoms for Depression in College Students with REBT: Implementation in Design and Practice." The Journal of Alternative and Complementary Medicine, 20(5), p. A147FiguresReferencesRelatedDetails Volume 20Issue 5May 2014 InformationCopyright 2014, Mary Ann Liebert, Inc.To cite this article:Jie Chen, Wenyue Zhang, Qian Wu, Xinjing Yang, Shuang Jiao, Xueqin Yang, Xuehong Ma, Sihan Wang, Zhuo Guo, Tianwei Guo, Wenhao Ma, Lan Sun, and Qinyi Lu.Psychological Intervention of Symptoms for Depression in College Students with REBT: Implementation in Design and Practice.The Journal of Alternative and Complementary Medicine.May 2014.A147-A147.http://doi.org/10.1089/acm.2014.5394.abstractPublished in Volume: 20 Issue 5: May 7, 2014PDF download
The Journal of Alternative and Complementary MedicineVol. 20, No. 5 Oral Abstract Session 03: Basic ScienceThe Alterations of Damage-Repair Related Signals in Hippocampal CA3 Region of Chronic Stress Rats after Electric-Acupuncture (EA) TreatmentZhuo Guo, Tianwei Guo, Xinjing Yang, Sihan Wang, Wenyue Zhang, Lan Sun, Yu Wang, Xuhui Zhang, and Chuntao ZhangZhuo GuoSearch for more papers by this author, Tianwei GuoSearch for more papers by this author, Xinjing YangSearch for more papers by this author, Sihan WangSearch for more papers by this author, Wenyue ZhangSearch for more papers by this author, Lan SunSearch for more papers by this author, Yu WangSearch for more papers by this author, Xuhui ZhangSearch for more papers by this author, and Chuntao ZhangSearch for more papers by this authorPublished Online:7 May 2014https://doi.org/10.1089/acm.2014.5010.abstractAboutSectionsView articleView Full TextPDF/EPUB Permissions & CitationsPermissionsDownload CitationsTrack CitationsAdd to favorites Back To Publication ShareShare onFacebookTwitterLinked InRedditEmail View article"The Alterations of Damage-Repair Related Signals in Hippocampal CA3 Region of Chronic Stress Rats after Electric-Acupuncture (EA) Treatment." The Journal of Alternative and Complementary Medicine, 20(5), pp. A5–A6FiguresReferencesRelatedDetails Volume 20Issue 5May 2014 InformationCopyright 2014, Mary Ann Liebert, Inc.To cite this article:Zhuo Guo, Tianwei Guo, Xinjing Yang, Sihan Wang, Wenyue Zhang, Lan Sun, Yu Wang, Xuhui Zhang, and Chuntao Zhang.The Alterations of Damage-Repair Related Signals in Hippocampal CA3 Region of Chronic Stress Rats after Electric-Acupuncture (EA) Treatment.The Journal of Alternative and Complementary Medicine.May 2014.A5-A6.http://doi.org/10.1089/acm.2014.5010.abstractPublished in Volume: 20 Issue 5: May 7, 2014PDF download