The effects of the feed with mawseed oil and corn oil on nutritional physiological functions of growing rats were observed.The result showed that in spite of having similar nutritional physiological function,the mawseed oil could observably depresse the triglyceride(TG)level in serum.It had the functions of strong antilipid peroxidation and adjusting uric acid metabolism.So mawseed oil is a kind of healthy edible oil resource

目的观察一种新型水溶性膳食纤维对高脂血症及糖耐量异常(IGT)患者及便秘患者的调节作用.方法每天补充剂量为10g,高脂血症患者、便秘患者观察30天,糖耐量异常患者观察半年.结果膳食纤维组血清甘油三酯由(4.39±4.09)mmol/L降为(2.56±1.91)mmol/L,血清总胆固醇由(6.63±0.63)mmol/L降为(5.49±1.11)mmol/L;试验前后比较差异有显著性(P＜0.05).IGT转为糖尿病的比例显著低于对照组和单纯膳食控制组.结论新型膳食纤维具有降低血脂及调节血糖作用,并能显著改善便秘患者的通便状况.

Objective To evaluate the efficacy of metformin and diet fibre intervention in preventing the conversion of impaired glucose tolerance (IGT) to type 2 diabetes mellitus.Methods The recruited 293 IGT subjects were diagnosed by 75 g OGTT (WHO, 1985), with their age more than 35 years and BMI more than 19 kg/m 2. They were divided into 4 groups, i.e. control (C) (72 cases), education (E) (57 cases), diet fibre (DF) (84 cases) and metformin (M) (80 cases) groups. The subjects of group E were given healthy diet education. The subjects of group DF were treated with diet fibre 12g daily, and group M were given metformin 0.75 g daily. 75 g OGTT was done every 6 months. They were followed 3 years. The primary end point was the development of diabetes based on 2 hour plasma glucose after 75 g glucose load. Results The IGT subjects consisted of 216 males and 77 females. 23 subjects (7.8%) were discontinued prematurely. At the end of the study, the fasting blood sugar (FBS) and post OGTT 1 hour glucose levels were slightly higher in group C, E, DF than baseline data, while both above glucose levels were significantly lower than baseline in group M( F=8.118, P<0.001, F=3.697, P= 0.012). The cumulative cases with conversion to diabetes were 16 (25.0%) in group C, 11(21.6%) in group E, 13(16.3%) in group DF, and 7( 9.33% ) in group M. Using the Chi square test the conversion rate of diabetes was significantly lower in group M than group C. The diabetes conversion rate was positively related to the age and FBS ( P <0.05) and was negatively related to the intervention methods ( P =0.013) using mono factor statistical analysis. And the diabetes conversion rate was positively related to the FBS( P = 0.03 ), and was negatively to the intervention methods ( P =0.034) using multi regression analysis. Conclusion Metformin is effective in delaying the conversion of IGT to type 2 diabetes mellitus. The diet fibre may also be effective in IGT intervention.

Body mass index (BMI), five skinfold-thickness measurements, three circumferences were measured and percentage of body fat (F%) was also measured by bioelectrical impedance in 988 healthy adults aged from 18 to 69 years, for 10-year age intervals. The results indicated that the changes in several anthropometric parameters depended on age and sex and reallocation of body fat on upper trunk was manifested clearly in male subjects over 30 years old and female subjects over 40 years old.

目的探讨下丘脑腹内侧核损伤性肥胖大鼠氨基酸代谢的变化.方法下丘脑腹内侧核损伤性肥胖大鼠用2 mA直流电造成下丘脑腹内侧核损伤后1、2、4、6、10及12周收集血样,分析血清氨基酸、葡萄糖及甘油三酯浓度.结果 (1)损伤后12周,肥胖大鼠的血清葡萄糖和甘油三酯浓度明显增高;(2)肥胖大鼠的血清支链氨基酸即缬氨酸、亮氨酸及异亮氨酸明显高于非肥胖组;(3)肥胖大鼠血清中的一些生糖性氨基酸如苏氨酸、甘氨酸、丙氨酸明显增高;(4)肥胖大鼠的血清精氨酸水平随肥胖的发展而呈进行性下降.结论下丘脑腹内侧核损伤性肥胖大鼠不仅血糖、血脂代谢紊乱,而且氨基酸代谢发生了异常的改变.

测定了６５例不同肺功能受损程度的慢性阻塞性肺疾病（ＣＯＰＤ）患者血浆氨基酸含量及其变化。根据患者肺功能及动脉血气的改变将研究对象分为４组：Ⅰ组为肺功能正常组，男１５例，女４例，平均年龄（６４．０５±１１．０１）岁；Ⅱ组为轻度肺气肿组；男１５例，女１例...

早在19世纪四十年代就有人考虑到营养状况可能与肿瘤发病有关,膳食蛋白摄入过低可以促进动物肿瘤的发生[1].自1994到1999年我们测定了58例肺癌患者的血浆氨基酸含量,并与我院同年龄的100例正常人对照,现将结果报道如下.

慢性阻塞性肺病(COPD)患者常伴有营养不良,而影响呼吸肌功能,降低通气量,进一步加重COPD.我们用同一种操作方法测定了65例肺功能受损程度不同的COPD患者血浆氨基酸含量,分析不同肺功能受损程度的COPD患者血浆氨基酸含量的变化.

基于肝脏病时有特殊的血浆氨基酸型式改变,Fischer于1976首先用含有丰富支链氨基酸（缬氨酸、亮氨酸、异亮氨酸）的FO80溶液纠正肝性脑病患者的血浆氨基酸不平衡,收到良好效果 〔1〕 。现将我们应用4.275％支链氨基酸溶液治疗肝性脑病37例的结果报道如下: