目的:观察茵栀黄口服液联合培菲康辅助治疗新生儿黄疸的效果观察.方法:80例新生儿黄疸患儿随机分为观察组和对照组,各40例,对照组给予蓝光、肝酶诱导剂及对症治疗,观察组在综合治疗的基础上口服茵栀黄口服液及培菲康,连用5d.观察两组患儿黄疸消退时间及每天胆红素下降速度.结果:观察组日均胆红素下降速度大于对照组,且下降至102.6μmol/L所需时间短,差异有统计学意义(P<0.01).结论:茵栀黄口服液联合培菲康治疗辅助治疗新生儿黄疸,治疗效果明显,是一种安全、有效、快速的治疗方式.值得临床推广.

目的:探讨布地奈德混悬液雾化吸入和妥洛特罗贴剂在咳嗽变异性哮喘儿童治疗中的作用.方法:选取2014年10月至2015年03月在我科门诊确诊为咳嗽变异性哮喘的患儿,随机分为两组,治疗组与对照组,各30例,对照组常规治疗,口服孟鲁司特及抗组胺药物,治疗组除以上常规治疗外每日雾化吸入布地奈德混悬液,每晚睡前应用妥洛特罗贴剂,比较两组患儿咳嗽缓解的时间及1周肺功能改善情况.结果:治疗组患儿咳嗽缓解时间及1周肺功能改善情况明显优于对照组,差异有统计学意义(P<0.05).结论:用布地奈德混悬液联合妥洛特罗贴剂治疗咳嗽变异性哮喘,临床疗效显著,值得临床推广使用.

Objective To do a cost-effect analysis to step-down therapy with oral Cefixime Granules as after Cefuroxime Sodium treatment for children infection.Method Step-down therapy with oral Cefixime Granules was compared with parenteral Cefuroxime Sodium therapy in a open-randomized comparative trial of children with middle-serious bacterial infections.Patients were allocated to three treatment groups: ①intravenous group,patients received Cefuroxime Sodium treatment 7 ～ 10 days;②step-down group,patient received Cefuroxime Sodium for 2 ～ 3 days,then oral Cefixime Granules 9 mg/(kg·d) total 7 ～ 10 days;③oral group,chirldren received Cefixime Granules 9 mg/(kg·d) treatment for 7 ～ 10 days.Results A total of 51 patients were included in three group,overall clinical cure rates in three groups were same.Step-down treatment with oral Cefixime Granules was a cost-effective therapy,through cost-effect analysis.56 RMB can been saved in walk-in patient and 59 RMB in a hospitalized patient to intravenus cephalosporin every day (P 0.01) .Conclusion Step-down Cefuroxime Sodium and Cefixime Granules treatment in middle-serious bacterial infection has superiority in cost-effect analysis.The patient has a good life-quality in treatment period.Of course oral Cefixime Granules is a good selection with cost-effect to middle bacterial infection.

目的探讨复方丹参注射液静滴对小儿肺炎及并发心力衰竭的疗效.方法小儿肺炎85例,并发心衰24例,分别随机分成治疗组和对照组.治疗组在抗感染基础上加用复方丹参静滴,疗程为5～7天.结果肺炎治疗组症状,体征消失天数及胸部X线片转阴与对照组比较差异有显著性;心衰组主要症状平均缓解时间,治疗组优于对照组,差异有显著性.治疗12h后两组心衰病人在多功能监护仪下心率、呼吸、氧饱和度值治疗组明显优于对照组,差异有显著性.结论复方丹参静滴治疗小儿肺炎及防治并发心力衰竭具有良好效果.

目的: 探讨硝苯吡啶、谷维素、肠胃康中西医结合治疗RAP的疗效.方法: 选择门、急诊除外器质性病变RAP患者165例, 随机分为2组.治疗组应用硝苯吡啶、谷维素、肠胃康冲剂, 疗程为1周.对照组应用解痉止痛剂(山莨菪碱、颠茄酊、维生素K1等)及谷维素治疗, 1个月后门诊随访.结果: 治疗组有效率为100%, 复发率为3.5%; 对照组有效率为82%, 复发率为42%.两者对比有显著差异.结论: 硝苯吡啶、谷维素、肠胃康中西医结合治疗RAP疗效显著, 复发率低.

目的:探讨布洛芬合并潘生丁治疗小儿难治性肾病综合征(RNS)的近期与远期疗效.方法:选择32例RNS患儿,在再次应用强的松方案或强的松逐渐减量的同时,加服布洛芬10～20mg/kg·d,潘生丁2～3mg/kg·d,均分三次口服,疗程3个月.结果:治疗后血浆总蛋白及白蛋白明显升高,24小时尿蛋白定量明显降低,治疗前后有显著性差异(P＜0.01),血肌酐治疗前后无显著性差异(P＞0.05).随访3～12年,远期疗效满意.结论:布洛芬合并潘生丁治疗RNS可获得较好的近期与远期疗效.

目的探讨肾病综合征(NS)与哮喘样发作的相互关系.方法回顾总结NS并发哮喘样发作10例的临床资料.结果 NS患儿中存在一定比例的哮喘样发作并发症的临床表现.结论 NS患儿产生哮喘样发作有其一定的潜在因素和发病基础.