With the widespread use of new equipment such as distributed photovoltaics, distributed energy storage, electric vehicles, and distributed wind power, the control of low-voltage distribution networks (LVDNs) has become increasingly complex. Acquiring the most recent topological structure is essential for conducting accurate analysis and real-time control of LVDNs. The signal injection-based topology identification algorithm is favored for its speed and efficiency. This research introduces an innovative topology identification algorithm based on signal injection, specifically designed to address the challenges of incomplete and inaccurate identifications caused by the missing data in feature signal records (FSRs). Based on the correlations among FSRs at various devices, the algorithm introduces a dual-axis completion strategy—both vertical and horizontal—to effectively address missing data. Subsequently, an inclusion detection process is devised to process the completed FSRs, culminating in an accurate topology of LVDNs. Based on the study of actual LVDN data, the results indicate that the proposed algorithm markedly enhances the completeness and accuracy of topology identification. This advancement offers a robust solution tailored to accommodate the dynamic and swiftly changing topological configurations of LVDNs.

Objective To understand the impact of the COVID-19 epidemic on HIV/AIDS case reporting and testing in Shenzhen to provide evidence for adjusting AIDS prevention and control under public health emergencies. Methods HIV/AIDS cases and test data in Shenzhen in the first quarter of 2018-2021 were collected and screened by the National AIDS Prevention and Control Information System. The data on COVID-19 cases were collected from the official website of the Shenzhen Health Commission. Chi-square test and global spatial autocorrelation were used to analyze the impact of COVID-19 on HIV/AIDS case reporting and testing in Shenzhen. Results HIV/AIDS cases reported in the first quarter of 2020 decreased by 38.86% from the same period in 2019（350 cases） and decreased by 37.24% from the same period in 2018（341 cases）. The HIV/AIDS cases reported in the first quarter of 2021 increased by 9.43% over the same period in 2019 and by 12.32% over the same period in 2018. In the first quarter of 2020 and 2021, the proportion of local registered cases was higher than that in the first quarter of 2019, and the proportion of junior high school education and workers/farmers cases was lower than that in the first quarter of 2018（P＜0.05）. In the first quarter of 2020, compared with the same period in 2019, the number of reported HIV cases of detention/drug rehabilitation, thematic investigation and medical treatment decreased by 88.89%, 76.47%, and 14.79%, respectively. During the same period, the number of tests from the same source decreased by 85.75%, 89.83%, and 36.68%, respectively. In the first quarter of 2020, compared with the same period in 2018, the number of HIV reported cases from detention/drug rehabilitation, thematic investigation, and medical treatment decreased by 80.00%, 69.23%, and 29.41%, respectively, During the same period, the number of tests from the same source decreased by 87.74%, 88.47%, and 25.49%, respectively. Conclusions The number of HIV/AIDS cases reported, the number of cases and tests in detention/drug rehabilitation, special investigation, and medical treatment decreased to different degrees compared with those before the COVID-19 epidemic in Shenzhen. We should scientifically assess the HIV/AIDS epidemic situation during the COVID-19 epidemic.

目的 了解深圳市艾滋病病毒(HIV)感染者中男男性行为人群(men who have sex with men,MSM)三种主要亚型分子网络特征,为控制MSM HIV的传播提供线索.方法 收集深圳市2017至2019年新报告MSM HIV感染者资料和血样,使用在线工具和Mega分析亚型、HyPhy计算成对基因距离、Cytoscape实现分子网络可视化及SPSS进行统计分析.结果 获得2848名MSM HIV感染者pol区基因序列,分为11种亚型,其中CRF07_BC、CRF01_AE、CRF55_01B占91.22％.三种亚型总入网率为32.32％,形成194个簇和1291条边.入网的MSM HIV感染者主要集中在35岁以下、汉族、未婚、外省或外籍、商业服务、无性病史、201～500个/μL CD4+T细胞,CRF01_AE感染者主要集中在高中或中专、CRF07_BC感染者主要集中在大专及以上、CRF55_01B感染者主要集中在初中及以下.CRF01_AE感染者中,201～500个/μL CD4+T细胞的入网率最高;CRF07_BC感染者易发生大簇聚集;CRF55_01B感染者中,初中及小学学历的入网率最高.结论 CRF01_AE感染者中,201～500个/μL CD4+T细胞数传播风险最高,CRF07_BC大簇中感染者传播风险较高,CRF55_01B感染者中,初中及小学的传播风险最高.

为提高微光夜视图像质量,提出一种基于图像分割和局部亮度调整的颜色传递算法。用简单线性迭代聚类结合K均值聚类对微光图像进行分割,在YCbCr颜色空间中利用子区域与参考图像每一个像素点上亮度的一致性,将匹配参考图像的颜色分量传递到目标图像的子区域,以目标图像纹理特征中对比度的值作为系数,调整目标图像子区域的亮度值,进行颜色空间转换并显示颜色传递结果。搭建了微光图像成像系统,进行了微光图像分割及完成了微光图像的颜色传递。结果表明,改进的分割算法将图像中不同的景物分割出来,得到的彩色微光图像的峰值信噪均值达到12.048 dB,比Welsh算法平均提高2.63 dB。

背景 肠易激综合征(irritable bowel syndrome,IBS)为功能性胃肠病,目前机制不清.新近研究表明低度炎症在其发生发展中起重要作用,然而IBS确切炎症标志物是什么,非特异性炎症标志物超敏C反应蛋白(hypersensitive C-reactive protein, hs-CRP)与IBS的诊断和分型之间有何关联均不清楚.目的 探讨罗马Ⅳ标准下非特异性炎症标志物hs-CRP在不同亚型IBS中的表达及其与炎症因子的关联.方法 选取2017-01/2019-01期间在扬州大学附属医院及江苏省苏北人民医院就诊的IBS患者177例及同时期体检的正常对照174例作为研究对象,分别采用免疫透射比浊法和酶联免疫吸附法对其血清hs-CRP和肿瘤坏死因子α(tumor necrosis factor-alpha,TNFα)的表达进行检测.结果 与健康对照相比,IBS患者血清TNFα、 hs-CRP水平均显著增高(P＜0.001);在5种不同的IBS亚型中,感染后IBS (postinfectious irritable bowel syndrome, PIIBS)和腹泻型IBS (diarrhea-predominant irritable bowel syndrome,IBS-D)组血清TNFα和hs-CRP水平较其他三种亚型显著增高(P＜0.001);并且IBS-D组(P＜0.001)和PI-IBS组(P＜0.05)血清hs-CRP水平与TNFα水平呈显著正相关,相关系数分别为0.814和0.432.结论 Hs-CRP可能可以作为潜在的炎症标志物用于IBS-D和PI-IBS的辅助诊断和治疗.

Objective:To explore a predictive model for outcomes of severe acute pancreatitis (SAP) patients.Methods:A retrospective study was conducted of 102 SAP patients from January 1,2016 to April 30,2018 from Taizhou Hospital in this study. The participants were divided into survival group and death group according to the outcome of 90 days after admission,88 cases were in survival group including 57 males and 31 females, aged 55.5 (40.3-69.8) years; 14 cases were in death group including 5 males and 9 females, aged 63.0 (50.8-80.8) years. Clinical data and laboratory indicators were compared between the two groups. Statistical analyses were performed to compare categorical variables. Chi-square automatic interaction detector (CHAID) was used to construct the prediction model of SAP patients′ outcomes. The study cohort consisted of SAP patients from August 1st 2018 to July 1st 2019 were collected to validate the prediction model.Results:(1)Statistical analyses were performed by chi square test and Mann-Whitney U test. There were statistically significant differences in the proportion of cardiovascular and cerebrovascular diseases, mechanical ventilation and septic shock, and also the Charlson complication index (CCI), the Ranson score and APACHEⅡscore(χ 2=5.554, P=0.018; χ 2=5.585, P=0.018; P=0.008; Z=-3.007, P=0.003; Z=-2.982, P=0.003; Z=-3.257, P=0.001), death group were higher than survival group. (2) The MPV, CRP, MCHC, pH, pCO2 and positive rates of NRBC were statistically different between survival group and death group( Z=-2.466, P=0.014; Z=-2.689, P=0.007; Z=-2.238, P=0.025; Z=-1.977, P=0.048; Z=-2.239, P=0.025; P=0.000).The NRBC-positive rate in the death group was higher than that in the survival group, while the other indexes were lower in the survival group.(3)The decision tree CHAID method obtains the prediction scheme: when it meets the Ranson score≤3, the SAP patients were judged to be alive; when it meets the Ranson score>3 and the NRBC in peripheral blood was negative, the SAP patients were judged to be alive; when it meets the Ranson score>3, the NRBC was positive and the APACHEⅡscore≤21, the SAP patients were judged to be alive; when it meets the Ranson score>3, NRBC was positive and APACHE Ⅱ>21, the SAP patients were adverse prognosis. (4) 50 SAP patients were collected in the validation group, with 43 actual survivors and 7 deaths. The accuracy rate of predicting the outcomes of SAP patients in validation group with the scheme was 94.0% (47/50). Conclusion:The NRBC combined with Ranson score system and APACHE II score system can predict the outcomes of SAP patients.

对上海某综合医院能耗进行了诊断分析,找出了用能系统存在的问题,主要包括空调系统、生活热水系统、照明系统、能源管理系统.提出了节能改造方案及调适建议,通过实测数据分析节能效果,综合节能率为15.51％.

Objective To evaluate the clinical curative effect and prognosis of hand-assisted laparoscopic (HALS) and laparoscopic assisted surgery for Siewert Ⅱ,Ⅲ gastroesophageal junction adenocarcinoma (AEG).Methods A retrospective analysis of 105 patients with advanced Siewert type Ⅱ and Ⅲ AEG between Jan 2012 and Jan 2013 was made on the operation time,amount of blood loss,number of lymph nodes dissected,postoperative complications,postoperative hospital stay and postoperative 5-year survival rate.Results HALS resulted in significantly shorter operation time and the average postoperative hospital stay [(203±54) min比(283±72) min,t=-4.902,P=0;(10±4) d 比(13±3)d,t=-0.939,P =0.002] for advanced Siewert type Ⅱ and Ⅲ AEG.There was no conversion to open surgery in HALS group,while there was 3 cases in laparoscopy assisted surgery group (x2 =4.118,P =0.042).5 year overall survival (OS) in HALS group was 46.7％ (95％ CI39.98-53.88),and it was 60.9％ for stage Ⅱ patients 37.8％ for stage Ⅲ.5 years OS rate was not significantly different between the two groups.Conclusion HALS compared with laparoscopy assisted surgery in the treatment of advanced Siewert type Ⅱ and type Ⅲ AEG has shorter operation time,higher safety operation,shorter postoperative recovery time.The number of patients with postoperative complications and the 5-year survival rate after surgery are not significantly different between the two groups.

目的 探讨基础胰岛素联合阿卡波糖治疗初诊老年糖尿病的临床疗效及安全性.方法 选取阆中市人民医院2016年7月—2017年6月收治的初诊老年糖尿病患者96例,根据随机数字表法分为参照组(n=48)和试验组(n=48).参照组患者单纯予以阿卡波糖治疗,试验组患者在参照组基础上给予基础胰岛素治疗.比较两组患者治疗前后空腹血糖(FPG)、餐后2 h血糖(2 hPG)、糖化血红蛋白(HbA1c)及正中运动纤维神经传导速度(MNCV)、胫MNCV、尺MNCV、正中感觉纤维神经传导速度(SNCV)、腓SNCV,并观察患者不良反应发生情况.结果 治疗前,两组患者FPG、2 hPG、HbA1c水平比较,差异无统计学意义(P>0.05);治疗后,试验组患者FPG、2 hPG、HbA1c水平低于参照组(P<0.05).试验组患者正中MNCV、胫MNCV、尺MNCV、正中SNCV、腓SNCV快于参照组(P<0.05).试验组患者不良反应发生率低于参照组(P<0.05).结论 采用基础胰岛素联合阿卡波糖治疗老年初诊糖尿病患者的临床疗效确切,其可有效降低患者血糖,加快神经传导速度,且安全性较高.

目的:探析体检中心对高血压患者实施健康教育的方法与临床效果.方法:选取2015年10月—2016年10月我院接受健康体检的高血压患者160例作为研究对象,并将其按照随机平均原则分为对照组和观察组,对照组采用常规宣教方法,观察组接受健康教育.对两组患者的临床效果进行观察和比较.结果:观察组患者的血压控制情况明显优于对照组,观察组患者在饮食结构、体育锻炼、服药依从性等都明显优于对照组,P<0.05,差异有统计学意义.结论:体检中心高血压患者实施健康教育,可以帮助患者改善生活质量,服药依从性提高,有重要的临床价值,在临床上值得推广与应用.

目的：观察针刺结合肌内效贴治疗急性面神经炎的临床疗效。方法：选取88例我院面神经炎患者作为研究对象，分为对照组17例、单纯针刺组35例、针刺结合肌内效贴组（研究组）36例。通过分析三组治疗前后的H-B分级及BR、运动传导（NCV）速度及患侧瞬目反射进行疗效评价。结果：研究组急性面神经炎的治愈率（22.2%）高于对照组治愈率（11.8%），差异具有统计学意义（P<0.05）；单纯针刺组及研究组治疗后与对照组治疗后相比较，潜伏期、波幅及患侧瞬目反射均有明显改善，差异有统计学意义（P<0.05）。结论：针刺结合肌内效贴扎技术治疗面神经炎疗效显著，值得推广。

Objective To theoretically study the non-invasive measurement method of blood hemoglobin in vivo based on the time-resolved approach combined with occlusion spectroscopy.Methods The dynamic dual wavelength time-resolved transmission was analyzed based on the artificial blood flow kinetics condition on a human finger model.The sensitivity of hemoglobin measurement was improved by Laplace transforming of time-domain data.The method was validated using hemoglobin with a mass concentration range of 6～16 g/dl.Results The simulation results showed that compared with the continuous wave method,the time-resolved method could provide higher detection sensitivity using Laplace transform parameter p =5 × 1010 s-1.Conclusions The sensitivity of hemoglobin measurement can be enhanced when early arriving photons are emphasized by Laplace transformingthe time-resolved transmission with a small positive parameter.

Objective:To probe into the influencing factors of self care ability of patients with radical cystecto-my double ureter skin colostomy at different periods after discharge.Methods:The questionnaire survey was used and the exercise of self care agency scale(ESCA)was applied to evaluate the self care ability of patients at different stages,and analyzed the influencing factors of the self care ability of patients.Results:Multivariate stepwise regression analysis showed that the factors with statistical significance included the gender,age,marital status,alcohol consumption,education level,occupation,personal monthly income,subjective support and objec-tive support.These 9 factors had an effect on the different dimensions of the patients’self care ability at dif-ferent periods at discharge and after discharge.Conclusion:The different dimensions of patients’self care abili-ty were affected by different factors at different periods of patients after discharge.The results showed that the nursing personnel should have a specific health education program for the patients at different periods after dis-charge,so as to further improve the patients’self care ability and life quality.

Objective To investigate the health condition of the workers in private enterprises in Langzhong.Methods Health examination data of 4 185 private enterprise workers were statistically analyzed.Results A total of 4 169(99.6%) in the 4 185 examined workers presented at least one health problem.The top ten diseases in terms of detection rate in descending order were: overweight and obesity,dyslipidemia,abnormal urine,hypertension,electrocardiogram(ECG) abnormalities,deflection of nasal septum,gallbladder disease,unusual liver function,thrombocytopenia and pharyngitis.Detection rates of fatty liver and liver function abnormalities in males were both significantly higher than that in females.While detection rates of abnormal urine,overweight and obesity in females were both significantly higher than that in males.Conclusion The health situation workers in private enterprise of Langzhong is not optimistic,and thus it is necessary to strengthen the community health education and intervention.

目的 探讨醒脑静注射液治疗脑梗塞的临床效果.方法 选取我院2011年1月-2012年6月收治的脑梗塞患者76例,随机分为观察组和对照组,每组各38例.观察组患者在常规治疗的基础上加用醒脑静注射液静脉滴注;对照组患者加用复方丹参注射液,治疗周期为14d,对比分析两组患者的临床治疗效果.结果 观察组38例患者显效23例,有效12例,无效3例,有效率为92.11%;对照组患者显效12例,有效15例,无效11例,有效率为71.05%.结论 醒脑静注射液治疗脑梗塞疗效可靠,无明显的药物不良反应和毒副作用,值得进一步研究和临床推广应用.

Objective: To observe the effects of Tongxinluo capsule on acute myocardial infraction patients of coronary heart disease and angina pectoris patient after PCI. Methods: 240 patients with unstable angina after PCI were randomly divided into treatment group( n =120) and control group( n = 120). Two groups were given routine treatment for 6-month treatment,Tongxinluo was added to treatment group. Observation indicator are angina frequent duration time,left ejection fraction( LVEF),ECG results and 6 minute Walk test. Results: After 6 months of treatment,treatment group showed significantly better improvement of all indicators than the control group( P <0. 05). Conclusion: Tongxinluo capsule has good curative effect on angina pectoris of coronary heart disease.

目的:评估奥卡西平联合神经阻滞是否可以提高治疗原发性三叉神经痛的临床效果。方法:选择原发性三叉神经痛患者60例,随机分为3组:奥卡西平治疗组（O组）、神经阻滞组（B组）和奥卡西平联合神经阻滞组（OB组）。采用视觉模拟评分（visual analogue scale,VAS）评估3组患者治疗前及治疗后第1、2、4周的疼痛分值以及睡眠、生活质量、MPQ总评分、患者自我评价等指标,同时观察患者的不良反应。结果:O组患者口服奥卡西平起效缓慢,但能有效缓解疼痛,治疗后第4周与治疗前VAS疼痛评分比较差异有显著性（P＜0.01）;B组治疗后第1、2、4周疼痛缓解效果与O组比较,差异有显著性（P＜0.05）;B组治疗后第4周与治疗前VAS疼痛评分比较有显著性差异（P＜0.01）;OB组奥卡西平联合神经阻滞组患者,治疗后第4周与治疗前VAS疼痛评分比较差异有显著性（P＜0.01）;且OB组较其他两组治疗后各时间点疼痛评分统计学差异显著（P＜0.05）。患者评价显示OB组较其他两组总体效果更让人满意（P＜0.05）。3组均有不良反应发生,其中O组不良反应发生例数最多;OB组不良反应发生例数最少,差异有显著性（P＜0.05）。结论:奥卡西平联合神经阻滞治疗原发性三叉神经痛有效且安全;其疗效优于单独服药和单独神经阻滞治疗。

The research progress of pesticide residue technology at home and abroad was introduced in the paper,espounded the technology of extraction,concentration and purification in food and agricultural products,respectively.It was also discussed gas chromatography,high-performance liquid chromatography,GC/MS,LC/MS and confirmation technology.The prospects of research and application of pesticide residue determination technology were analyzed in future.