Objective To observe the curative effect and adverse reactions of three-dimensional conformal radiotherapy and GemOx chemotherapy for locally adanced pancreatic cancer .Methods 24 patients both confirmed by pathology or clinical diagnosis as locally adanced pancreatic cancer received three-dimensional conformal radiotherapy ,plan the 6 MV-X line doses of DT 60~70 Gy,2~2.5 Gy/time,and 2 cycles of GemOx chemotherapy ( gemcitabine 1000 mg/m2 ,d1,d8;oxaliplatin 130 mg/m2,d1),maintain 2 cycles of GemOx chemotherapy after radiotherapy ,each cycle was 21 days,clinical curative effect,benefit re-action and adverse reactions were observed .Results Among 24 patients,there were complete remission 1 case (4.2%),partial remission 10 cases(41.6%),stable 12 cases (50.0%),progression 1 case (4.2%),effective rate was 45.8%;6-month surviv-al rate was 87.5%(21/24),12-month survival rate was 58.3%(14/24),24-month survival rate was 12.5%(3/24),the medi-an survival time was 11.8 months;CBR assessment:without jaundice drainage in 3 cases,jaundice subsidised after treatment in 2 cases (66.7%),21 cases of abdominal pain in the back before treatment (87.5%),after treatment the effective rate was 90.5%(19/21);Patients'general Karnofsky score increased by 20 points in 18 cases,which was above 75.0%;Adverse reaction were nausea、vomiting in 13 cases (54.2%),leukocytopenia 16 cases (66.7%),thrombocytopenia 9 cases degree (37.5%),of which Ⅰdegree and Ⅱdegree were respectively 10 cases(41.7%),12 cases(50.0%),5 cases(20.8%);Ⅲ degree were re-spectively 3 cases (12.5%),4 (16.7%),3 cases (12.5%);Ⅳdegree thrombocytopenia 1 case(4.2%).Conclusion Three-dimensional conformal radiotherapy combined GemOx for locally adanced pancreatic cancer has good relieve symptoms and local control effect ,it can improve survival time and the quality of life of patients with tolerable adverse reactions ,it is worthy of clinical popularization .
局部复发或未控及远处转移是食管癌放疗失败的主要原因,为寻求食管癌放疗的最佳方法,作者于2002年1月至2004年1月间进行了食管癌后程加速超分割放疗配合 LFP 方案化疗的临床观察,现报道如下。
目的 调查江苏省东台市农村的癌痛患者疼痛和治疗情况,分析其影响因素,为基层癌痛规范化治疗的推广提供依据.方法 采用自行设计的癌症患者疼痛及治疗情况调查问卷,于2011年上半年对205例癌症患者进行调查.结果 45例患者按三阶梯原则治疗,139例患者疼痛部分缓解,40例患者疼痛轻度缓解,26例患者疼痛没有得到缓解.结论 农村患者癌痛控制不佳,建议继续把癌症三阶梯止痛知识普及到基层单位和农村地区,使患者在家中即能得到方便、有效的治疗.
<正>癌性疼痛是由于癌症本身或治疗(包括手术、化疗、放疗)有关的以及精神、心理和社会等原因引起的疼痛,发生率约占晚期癌症的70%,是癌症患者常见的、令人恐惧的并发症,不仅对躯体有损伤,在心理上还可产生焦虑、抑郁,带来显著的消极作用,严重影响患者的生活质量,更会加重病情的恶
OBJECTIVE:To observe the short-term curative effect of treating malignant tumor with compound glycyrrhizin injection plus chemotherapy and the effect of the combined therapy on liver function.METHODS:A total of62patients with malignant tumor were randomly divided into two groups:the treatment group was assigned to receive compound glycyrrhizin injection(60ml)combined with chemotherapy,and control group receive single conventional chemotherapy,the short-term curative effect and the impact on liver function between groups were compared.RESULTS:The total effective rates were51.6%and32.8%,respectively for the treatment group and the control group(P0.05),patients receiving the combined therapy had a lower rate of liver functional lesion than did those receiving single chemotherapy.CONCLUSION:Compound glycyrrhizin injection serves as an assistant of chemotherapy in treating malignant tumor.
近年来,恶性肿瘤的发病率在不断增加,恶性心包积液患者也有增多趋势,易造成急、慢性心包填塞[1],如不及时治疗会造成死亡.以往对恶性心包积液行单纯心包穿刺抽液治疗,由于抽液不彻底,引流不尽,即使腔内注射化疗药物,效果也较差,且反复穿刺容易引起心脏损伤等并发症.我院2000年1月至2003年1月开展心包腔内置管化疗取得了满意的疗效,现报告如下:
经导管肝动脉栓塞化疗(TAE)已成为肝癌最有效的治疗方法之一,其疗效与肿瘤内碘油化疗药物沉积的程度有关.1993年以来我们对75例巨块型肝癌进行TAE治疗后选出12例肿瘤染色不全的病例,采用电视透视下经皮酒精碘油补充栓塞治疗取得较好疗效,现介绍如下.