There have been studied the long-term results of OPCAB in elderly patients. From 2001 to 2009 1146 patients were underwent OPCAB. Two groups of patients were formed. The first group included patients aged 70 years and older (n=43). The second group included patients aged less than 70 years (n=215). Survival of patients older than 70 years (group1) after surgery was significantly worse than that of patients who have not reached this age (group 2). Frequency of MACEhas no significant difference for both groups of patients.

We compared outcome of coronary artery bypass grafting (CABG) in 50 patients with coronary artery disease (CAD) and type 2 diabetes mellitus (DM) and 50 non-diabetic patients with CAD. The patients of both groups had no differences concerning age, gender, clinical and stenoses of coronary artery. The operative mortality was 0% in diabetic patients and 0% in non-diabetic. Perioperative complications were the following: myocardial infarction 4% in diabetic patients and 2% in non-diabetic (p=0,88), stroke 2% and 2% (p=0,95), arterial fibrillation 6% and 10% (p=0,78), bleeding 0% and 2% (p=0,83). The findings indicated that the presence of type 2 DM in patients with CAD has no significant impact on hospital mortality and the incidence of major complications.

One hundred fifty four patients with clinical evidence of infective endocarditis were evaluated. We had carryed out analysis of indications for surgical treatment of infective endocarditis. In this paper we had show peculiarities of surgical technique, artificial circulation and myocardial protection. A new method of intracardiac debridement of infection nidus by bacterial proteinase immobilazed on polymeric matrix had based. With the aim of evidence of new method efficacy a medical case is demonstrated.

The comparative analysis of three types of anaesthesia benefit in operations with cardiopulmonary bypass was carried out. The advantage of inhalational anaesthesia with the use of sevofluran was revealed. The use of sevofluran allows to lower outlay of opioids anaesthetics and activate patients in early period after operation.