肝细胞癌（HCC）是肝脏最常见的原发性恶性肿瘤。在慢性肝脏损害基础上由肝硬化结节发展演变为HCC的多步癌变模式和主要病理改变已得到公认，这些改变成为了影像学检出、诊断和评价HCC的重要依据。本文拟对肝硬化结节多步癌变的病理特征、HCC的影像学诊断及鉴别诊断进行归纳总结，旨在加深影像医师对HCC影像表现的认识，帮助提高影像诊断HCC的能力。

目的 总结放射组学的发展过程及其在临床中的应用.方法 复习放射组学相关文献,对其发展过程及临床应用进行总结.结果 放射组学产生于大数据的背景下,已在肿瘤的诊断、鉴别诊断、疗效评估等领域展开应用.结论 放射组学是大数据时代精准影像医学的重要组成部分.

Objective To investigate hotspots from researches on radiomics in recent five years. Methods Bibliographies from research literature of radiomics in recent five years in PubMed database were downloaded. The publication years, journals, countries of publication, the first authors and the frequency of Mesh major topics were counted by Bicomb 2.0 software. The affiliations were analyzed artificially. Mesh major topics appeared no less than two times were intercepted as high frequency ones and the high frequency Mesh major topics matrix were formed. SPSS 22.0 statistical software were applied for clustering analysis with matrix to get the topic hotspots. Results A total of 56 literatures were screened out, among which, there were 2 (3.6%,2/56), 3 (5.4%,3/56) ,4 (7.1%,4/56) ,28 (50.0%,28/56) and 19 (33.9%, 19/56) literatures published in 2012, 2013, 2014, 2015, 2016, respectively. Twenty one of 56 (37.5%, 21/56) literatures published in 5 journals which were contained in 34 journals from 10 countries, were divided into core area, in terms of published articles of no less than 3. Frequency distribution were 18 (US), 6 (England), 2 (Netherland and Germany) and 1 (Switzerland, France, Spain, Ireland, Turkey, India), respectively, for 34 journals (56 literatures).Among the 56 literatures, US, Netherlands and Canada contained 27, 10, 5, respectively. England had 2, as same as China, France and Czech Republic, and 1 in Germany, Spain, Hungary, Korea, Japan, India, respectively, in terms of first authors affiliated research institution. The number of high frequency major topics was 11 and among them 2 research hotspots (A and B) were clustered. One (A) was computer-aided diagnosis of non-small cell lung cancer, combined with methods of three-dimensional processing, another (B) was PET combined with computer-aided and image integration technology in the diagnosis of lung tumors. Conclusion Hotspots from researches on radiomics in recent five years are focused on computer-aided diagnosis of non-small cell lung cancer, combined with methods of three-dimensional processing, and PET combined with computer-aided and image integration technology in the diagnosis of lung tumors.

目的 基于急性胰腺炎新亚特兰大分类,比较Balthazar CT严重指数(Balthazar computed tomography severity index,CTSI)、修正CT严重指数(modified computed tomography severity index,MCTSI)和胰腺外炎症评分(extrapancreatic inflammation on CT,EPIC)对急性胰腺炎早期发生器官衰竭的预测价值.方法 回顾性分析2013年12月至2014年1月期间笔者所在医院因急性胰腺炎入院治疗患者的临床资料,绘制其CTSI、MCTSI、EPIC、局部并发症及急性胰腺炎严重程度床边指数(beside index of severity in acute pancreatitis,BISAP)和新日本急性胰腺炎严重程度评分(new Japanese severity score,NJSS)诊断早期器官衰竭的受试者特征曲线,计算曲线下面积.结果 ①54例患者基线资料如年龄、性别、首次腹痛至检查间隔时间方面的差异均无统计学意义(P＞0.05).②CTSI、MCTSI、EPIC及局部并发症评价早期器官衰竭具有统计学意义(P＜0.05).临床评分系统BISAP和NJSS评价早期器官衰竭无统计学意义(P＞0.05).结论 CT评分系统能在早期准确预测急性胰腺炎发生器官衰竭情况.

目的 探讨移植后淋巴组织增生性疾病的影像学特点,以提高对该疾病的认识与影像学诊断水平.方法 通过文献复习的方法,对移植后淋巴组织增生性疾病在腹部、胸部、头颈部和中枢神经系统的影像学表现及其流行病学特征、发病机理与病理类型进行全面综述.结果 移植后淋巴组织增生性疾病是移植后主要由EB病毒感染和免疫抑制治疗引起的一组不同病理类型的淋巴组织增生性疾病.在影像学检查中发现可疑病灶通常为诊断该病的第一线索,不同部位的移植后淋巴组织增生性疾病具有各自不同的影像学特点.结论 熟悉移植后淋巴组织增生性疾病及其影像学特点对于诊断该疾病、明确活检取样部位以及评估治疗效果方面有着重要的意义.

目的 了解最近5年来胰腺肿瘤分子影像学领域的研究状况,为广大专业研究人员提供参考信息.方法 下载PubMed数据库中最近5年发表的胰腺肿瘤分子影像学研究文献题录,使用Bicomb 2.0软件统计分析文献的发表年代、来源期刊及期刊所属国家、第一作者以及高频主要主题词分布情况,对文献第一作者所属研究机构进行人工逐条统计分析.将出现频次不小于2次的主要主题词作为高频主要主题词,建立词篇矩阵,使用SPSS22.0软件进行聚类分析,得到该领域的研究热点.结果 筛选出相关文献28篇,获得该领域研究热度趋势、来源期刊分布、各国研究热度等数据资料.高频主要主题词共计20个,通过对高频主要主题词进行聚类分析,得到5个主要研究热点方向.结论 最近5年来胰腺肿瘤分子影像学研究热点主要集中在治疗与基因、诊断与代谢、核医学成像、药理学及病理学5个方向.

本文主要使用的是中英文献的对比方法,研究集体主义文化下的中国和个人主义文化下的美国职业女性工作家庭冲突的异同;主要探讨了文化作为一个中介因素,如何影响了职业女性工作家庭冲突及其前因和结果变量。

"Sabine Women" is a great portrait send and record revolutionary painter Chuck- Louis David works of art.The work was born in the context of the revolution, when the painter`s will a reversal.This work which assembled his many painting features is an extremely the neoclassical representatives paintings.This article use art psychological theory proposed by Arnheim to analysis from composition balance, empty between levels, light and dark colors, and tension dynamic for providing a new perspective to interpret the "Sabine Women".

<正>文学按体裁可以分为诗歌、小说、散文、戏剧四部分。与其他文学体裁相比,小说的容量较大,它可以细致的展现人物性格和人物命运,可以表现错综复杂的矛盾冲突,同时还可以描述人物所处的社会生活环境,因此小说可以提供整体的,广阔

paper summarizes,analyzes and evaluates the rural social influence of rural microcredit and puts forward some suggestions for its future development by referring and consulting articles published on The People's Daily from 2000 to 2006 in China.