Objective:To establish a quick and convenient method for detecting human adenoviruses (Human adenoviruses, HAdV) based on immunochromatographic assay (ICA).Methods:Two antibody clones, 3C11 and 7E6 were found to bind to all tested HAdVs and then subsequently processed into ICA. The specificity and sensitivity were evaluated using representative strains of the respiratory HAdV types, including HAdV-1, 2, 3, 4, 5, 6, 7, 10 and a gastroenteric type HAdV-41 together with the original throat swabs of 10 HAdV patients confirmed by nuclear acid testing (NAT).Results:The ICA exhibited high specificity to HAdVs and its detection limitation ranged from 0.16 to 10 3 half tissue culture infectious dose (TCID 50)/ml for different types of HAdVs. All clinic samples with successful virus isolation tested by this ICA showed positive result . Conclusions:The ICA developed in the present study will be suitable for HAdVs screening in clinic setting, especially for those of respiratory types.
舞蹈欣赏古今大部分舞蹈是供人们欣赏的。如中国唐代的《霓裳羽衣舞》、《七盘舞》等,以及现今民间广泛流行的各种舞蹈,如汉族的灯舞、花舞、鼓舞、狮子舞、蚌舞、扇舞,维吾尔族流行的多朗舞,藏族流行的弦子舞,苗族流行的芦笙舞,土家族流行的摆手舞,傣族流行的孔雀舞等等,它们虽然不一定含有十分明朗和深刻的思想内容,但却都能给人带
Scientists and experts forecasted there would be a new flu pandemic throughout the world.To draw lessons from history, make an analysis of current situation and discuss the relationship between prevention flu pandemic and creating an harmonious society.
端粒是真核细胞线性染色体末端的一种特殊结构,由于DNA的末端复制问题和自由基对端粒DNA的不可修复性损伤而使其缩短,进而导致细胞的衰老和死亡.端粒酶是一种具有保持种属特异性端粒长度的酶,在延缓机体的衰老中发挥重要的作用.
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