目的 观察中药膏摩治疗气滞血瘀型慢性非细菌性前列腺炎的临床疗效.方法 选取2020 年1 月—2022 年10 月北京中医药大学房山医院男科治疗的气滞血瘀型慢性非细菌性前列腺炎患者120 例,采用随机对照方法将患者分为治疗组、对照组1、对照组2,每组40 例.治疗组采用前列腺膏膏摩治疗,对照组1 采用凡士林膏膏摩治疗,对照组2 采用前列安通片口服,3 组均治疗4周.观察3 组患者治疗前后慢性前列腺炎症状指数(NIH-CPSI)评分、中医证候积分、前列腺液中白细胞数量的变化,评估3 组临床疗效.结果 治疗后,3 组患者NIH-CPSI评分、中医证候积分、前列腺液中白细胞数量均较治疗前明显降低(P均<0.05),且治疗组NIH-CPSI评分、中医证候积分、前列腺液中白细胞数量均明显低于对照组 1 与对照组 2(P均<0.05).治疗组总有效率为94.7%(36/38),明显高于对照组1 的56.8%(21/37)和对照组2 的71.8%(28/39),差异均有统计学意义(P均<0.05).结论 采用前列腺膏膏摩治疗气滞血瘀型慢性非细菌性前列腺炎,可明显缓解患者疼痛症状,改善排尿异常,提高生活质量.

目的 评价补肾消癃汤联合坦洛新治疗良性前列腺增生症的疗效及对血清睾酮(T)、雌二醇(E2)的影响.方法 选取2018年1月至2019年12月北京中医药大学房山医院诊治的70例良性前列腺增生症患者作为研究对象,采用随机数字表法分为治疗组(n=35)和对照组(n=35).治疗组采用补肾消癃汤+坦洛新治疗,对照组采用单纯坦洛新治疗,疗程8周,停药后随访2周.观察两组治疗前后国际前列腺症状评分(IPSS)、生活质量评分(QOL)、最大尿流率(Qmax)、膀胱残余尿量(PVR)、前列腺体积(PV)、中医证候积分、T和E2水平,以及停药2周后IPSS,记录不良反应.结果 对照组完成治疗30例,总有效率66.7％,显效率30.0％;治疗组完成32例,总有效率87.5％,显效率62.5％;两组疗效差异具有统计学意义(P<0.05).两组治疗后除PV无明显变化(P>0.05),IPSS、QOL、Qmax、PVR、中医证候积分均有明显改善(P<0.05);治疗组在IPSS、QOL、Qmax、PVR、中医证候积分方面改善明显优于对照组(P<0.05).治疗组血清T、E2及T/E2变化显著(P<0.05),对照组无显著变化(P>0.05).治疗组停药2周后IPSS较停药前无明显变化(P>0.05),对照组停药2周后IPSS较停药前明显升高(P<0.05).结论 补肾消癃汤联合坦洛新可明显改善BPH临床症状,显著提高临床疗效,并且具有一定的停药稳定性,对血清T、E2水平有显著影响.

目的 评价补肾消癃汤治疗肾虚血瘀型前列腺增生症(BPH)的临床疗效及安全性.方法 将符合纳入标准的106例BPH患者随机等分为治疗组和对照组,治疗组给予补肾消癃汤治疗,对照组给予前列舒乐颗粒治疗,疗程均为8周,停药后观察2周.观察2组治疗前后国际前列腺症状评分(IPSS)、生活质量(QoL)评分、最大尿流率(Qmax)、膀胱残余尿量、中医证候积分变化情况,统计2组疗效、不良反应发生情况,比较2组治疗结束及随访2周时IPSS各项评分.结果 治疗组完成治疗50例,总有效率为70.0％(35/50),对照组完成治疗49例,总有效率为51.0％(24/49).2组疗效比较具有显著性差异(P<0.05);2组治疗后IPSS评分、QOL评分、Qmax、膀胱残余尿量、中医证候评分均有明显改善(P均<0.05),而前列腺体积无明显变化(P>0.05);治疗组IP-SS评分、QOL、Qmax、中医证候积分改善情况明显优于对照组(P均<0.05);停药2周后,治疗组患者IPSS总分和各单项评分与2周前比较无显著性差异(P均>0.05),对照组停药2周后尿不尽、尿线细、夜尿次数及IPSS评分较停药前明显升高,且明显高于治疗组(P<0.05).结论 补肾消癃方可明显改善BPH引起的临床症状,治疗BPH安全、有效.

Objective To study the clinical efficacy of Bushen Huoxue decoction in the treatment of varicocele infertility and its influence on epididymis function and sperm vitality. Methods A total of 98 patients with varicocele infertility who were treated in our hospital from August 2016 to July 2018 were selected. The patients were randomly divided into control group of 49 cases and study group of 49 cases. The patients in the control group were treated with Maizhiling plus Wuzi Yanzong pill; the patients in the study group were treated with Bushen Huoxue decoction. After 12 weeks of treatment, the clinical efficacy of the patients was evaluated. The semen quality (including semen volume, sperm density, sperm motility, forward-moving sperm), sex hormones, and seminal plasma neutral α-glucosidase in the two groups were compared before and after treatment. After the end of treatment, the patients were followed up for 3 months to observe the pregnancy of the patients' spouse. Results After treatment, the total effective rate of the study group was87.76％, and the total effective rate of the control group was 69.39％. The semen quality, sex hormone and neutral α-glucosidase levels in the study group were better than those in the control group (P<0.05). Conclusion Bushen Huoxue decoction has a significant clinical effect in treating varicocele infertility. It can improve the semen quality, improve testosterone level and seminal plasma neutral α-glucosidase level, and improve the fertility of patients with varicocele.It is worthy of clinical promotion.

Objective To evaluate the efficacy and safety of Fenghuaqianqing Tea in treatment of benign prostatic hyperplasia.Methods A randomized control and multi-center clinical trial was applied.The patients were divided into observation group(48cases)and control group(48cases).The control group were treated with Fenghuaqianqing Tea(2 bags/time,bid,po),while the observation group received Terazosin Hydrochloride Tablets(1tablet,qn,po).A course of treatment last 8 weeks including the one observation course.Then there would be a 2-week follow-up visit and the ad-verse drug reactions were statistically collected.Results Treatment group,45 cases completed,detached 3 cases,control group,45 cases completed,3 cases lost.The total effectiveness rate of treatment group was 73.3% with significant efficien-cy rate of 11.1% and that of control group was 51.1% with significant efficiency rate of 4.4%.There were significant differences in clinical efficacy between the two groups(P <0.05).The I-PSS,QoL,Qmax and residual urine volume were obviously improved in both groups after treatment(P <0.05),In I-PSS single integrals,the treatment group was superior to the control group(P <0.05)in the improvement of intermittent urination,the appearance of the urine line,and the Urina-tion difficulty.whereas no changes were found in prostate gland volume;Compared with control group,treatment group was better in the improvement of I-PSS,QoL,Qmax(P <0.05),but there was no significant difference in reducing residual volume and prostate gland volume between the 2 groups.Drug withdrawal two weeks later,Comparing the curative effect for effective cases,The treatment group patients score on I-PSS,which has no statistical difference compared with 2weeks ago (P >0.05);The control group patients score on I-PSS,which has statistical difference compared with 2 weeks ago(P <0.05).Comparison between groups,the treatment group patients and the control group was statistically difference on I-PSS score(P <0.05).Conclusion Fenghuaqianqing Tea can significantly improve clinical syndromes caused by BPH and preferably maintenance treatment effect,which is a safe and effective medicine in treating BPH with broad development and application prospects.

目的：观察穴位电刺激联合栓剂治疗Ⅲ型前列腺炎(气滞血瘀型)的临床疗效及安全性。方法采用阳性病例对照方法，用编码表将120例患者分为栓剂组、电刺激组、联合组，每组40例。治疗结束后栓剂组完成38例，电刺激组完成36例，联合组完成38例。栓剂组单独给予前列安栓纳肛，睡前1粒，每天1次；电刺激组单独给予穴位电刺激，穴位电刺激选取前列腺穴、中极穴、足三里穴、三阴交穴。刺激参数为2/100 Hz疏密波、交替输出，每次30分钟，每天1次；联合组给予前列安栓联合穴位电刺激。疗程4周。以慢性前列腺炎症状指数评分标准量表、中医证候评分为主要评价指标，观察上述指标的积分变化，进行统计学分析，同时记录不良反应。结果栓剂组总有效率63.2％，电刺激组总有效率52.8％，联合组总有效率78.9％。三组比较，有统计学差异( P<0.05)。慢性前列腺炎症状指数评分标准积分组间比较，联合组在疼痛不适、症状总分方面与栓剂组、电刺激组比较差异有统计学意义(P<0.05)；中医症候积分组间比较，联合组在疼痛不适、性功能障碍、排尿症状、精神症状、总分方面与栓剂组、电刺激组差异比较均有统计学意义( P<0.05)。各组在治疗期间未出现明显不良发应。结论穴位电刺激联合前列安栓纳肛治疗Ⅲ型前列腺炎(气滞血瘀型)安全、有效。