男科疾病往往病情复杂,病因不明,临床疗效不佳.李海松教授临床用药不拘一格,常借鉴内科、妇科等其他学科的用药经验,灵活运用于男科疾病的治疗中.少腹逐瘀汤本用于治疗寒凝血瘀证痛经等妇科疾患,教授取中医异病同治之理,认为男性所属器官解剖位置特殊,且男科疾病发病部位局限,多以少腹部疾患为主,契合少腹逐瘀汤用药病位;从中医认为,男科疾病多滞、多瘀,血瘀病机贯穿男科疾病始终,运用少腹逐瘀汤治疗男科疾病契合本方主治;临床中,常将少腹逐瘀汤用于男科慢性前列腺炎、不射精症、血精症等方面的治疗,并根据患者寒热气血脏腑特点辨证施治,临床上取得了显著疗效.

糖尿病性勃起功能障碍(DIED)是勃起功能障碍(ED)常见的类型,5型磷酸二酯酶(PDE5)抑制剂是现代医学的一线治疗药物,虽然临床疗效满意,但过于重视局部病变而忽视整体,整体效果欠佳.李海松教授认为DIED的核心病机是瘀血内阻、脏腑失调,提出衷中参西、身心同治的理念,主张中西医并用,采用对因治疗、对证治疗、身心同治等论治DIED,取得了满意的临床疗效.

男性不育症病因复杂,临床上将其特点归结为多样性、复杂性、不明性等.祖国医学对不育症认识较早,在病机病性上以虚为重点,在治疗上以补肾填精为大法的趋势.从古至今,在治疗男性不育症上多用一些补肾之品,但是随着生活方式和工作环境的改变,"毒邪"致病呈现重要的地位,同时,受孕率下降和胎停概率升高都与"毒邪"有着密不可分的关系.因此,在"毒邪"肆虐的时代大背景下,在补肾生精治法的同时,考虑从毒论治将为男性不育症提供一种新的思路和方向.

Abstract Background: Premature ejaculation (PE) is a form of male sexual dysfunction. As people's lifestyle changes and the population ages, the incidence of PE continues to increase. Chinese patent medicines have been widely used in clinical practice as derivatives of traditional Chinese medicine (TCM). Many clinical trials have proven that Chinese patent medicine has a significant effect in the treatment of PE. In this systematic review, we aim to evaluate the effectiveness and safety of Chinese patent medicine for PE. Methods: We will search for PubMed, Cochrane Library, AMED, Embase, WorldSciNet, Nature, Science online and China Journal Full-text Database, China Biomedical Literature CD-ROM Database, and related randomized controlled trials included in the China Resources Database. The time is limited from the construction of the library to September 2019. We will use the criteria provided by Cochrane 5.1.0 for quality assessment and risk assessment of the included studies, and use the RevMan 5.3 and Stata 13.0 software for meta-analysis of the effectiveness, recurrence rate, and symptom scores of PE. Ethics and dissemination: This systematic review will evaluate the efficacy and safety of TCM for treating PE. Because all of the data used in this systematic review and meta-analysis have been published, this review does not require ethical approval. Furthermore, all data will be analyzed anonymously during the review process Trial. Trial registration number: PROSPERO CRD42017065316

Background: Premature ejaculation (PE) is a form of male sexual dysfunction. As people's lifestyle changes and the population ages, the incidence of PE continues to increase. Chinese patent medicines have been widely used in clinical practice as derivatives of traditional Chinese medicine (TCM). Many clinical trials have proven that Chinese patent medicine has a significant effect in the treatment of PE. In this systematic review, we aim to evaluate the effectiveness and safety of Chinese patent medicine for PE. Methods: We will search for PubMed, Cochrane Library, AMED, Embase, WorldSciNet, Nature, Science online and China Journal Full-text Database, China Biomedical Literature CD-ROM Database, and related randomized controlled trials included in the China Resources Database. The time is limited from the construction of the library to September 2019. We will use the criteria provided by Cochrane 5.1.0 for quality assessment and risk assessment of the included studies, and use the RevMan 5.3 and Stata 13.0 software for meta-analysis of the effectiveness, recurrence rate, and symptom scores of PE. Ethics and dissemination: This systematic review will evaluate the efficacy and safety of TCM for treating PE. Because all of the data used in this systematic review and meta-analysis have been published, this review does not require ethical approval. Furthermore, all data will be analyzed anonymously during the review process Trial.

中医临床带教在临床实习中有着重要而积极的作用,笔者通过多年建设名老中医传承工作站的经验和临床带教中的思考,总结出了一套"以名老中医为中心"的临床带教模式.将名老中医学术经验集替代中医临床教材作为贯通中医理论与临床实践的桥梁;通过对话名老中医,使学生正确认识中医的地位与价值;通过名老中医教学查房、跟诊名老中医抄方学习来锻炼中医思维,坚定中医信念;通过参加名老中医学术经验研讨会议思考中医的继承与发展问题.该教学模式充分发挥了名老中医在中医教学中的价值,突出锻炼中医思维,重视中医基本技能训练,启发中医相关问题思考,值得在临床教学中推广.

Objective To evaluate the efficacy and safety of Fenghuaqianqing Tea in treatment of benign prostatic hyperplasia.Methods A randomized control and multi-center clinical trial was applied.The patients were divided into observation group(48cases)and control group(48cases).The control group were treated with Fenghuaqianqing Tea(2 bags/time,bid,po),while the observation group received Terazosin Hydrochloride Tablets(1tablet,qn,po).A course of treatment last 8 weeks including the one observation course.Then there would be a 2-week follow-up visit and the ad-verse drug reactions were statistically collected.Results Treatment group,45 cases completed,detached 3 cases,control group,45 cases completed,3 cases lost.The total effectiveness rate of treatment group was 73.3% with significant efficien-cy rate of 11.1% and that of control group was 51.1% with significant efficiency rate of 4.4%.There were significant differences in clinical efficacy between the two groups(P <0.05).The I-PSS,QoL,Qmax and residual urine volume were obviously improved in both groups after treatment(P <0.05),In I-PSS single integrals,the treatment group was superior to the control group(P <0.05)in the improvement of intermittent urination,the appearance of the urine line,and the Urina-tion difficulty.whereas no changes were found in prostate gland volume;Compared with control group,treatment group was better in the improvement of I-PSS,QoL,Qmax(P <0.05),but there was no significant difference in reducing residual volume and prostate gland volume between the 2 groups.Drug withdrawal two weeks later,Comparing the curative effect for effective cases,The treatment group patients score on I-PSS,which has no statistical difference compared with 2weeks ago (P >0.05);The control group patients score on I-PSS,which has statistical difference compared with 2 weeks ago(P <0.05).Comparison between groups,the treatment group patients and the control group was statistically difference on I-PSS score(P <0.05).Conclusion Fenghuaqianqing Tea can significantly improve clinical syndromes caused by BPH and preferably maintenance treatment effect,which is a safe and effective medicine in treating BPH with broad development and application prospects.

Objective:To observe the effects of Zuogui pill on patients with oligoasthenospermia of kidney yin deficiency type.Methods:220 patients with oligoasthenospermia were treated with Zuogui pill for 90 days.Changes in semen parameters and sex hormones level before and after treatment and the clinical efficacy were observed and compared.Results:The total clinical efficiency was 86.1％.Differences in the sperm quantity,sperm density,semen of the total number of sperm,forward motile spermatozoon and sperm motility before and after treatment were significant (P ＜ 0.05).The testosterone level and luteinizing hormone level after treatment were significantly higher than those before treatment,with statistically significant difference (P ＜ 0.05).Differences in the levels of follicle stimulating hormone,prolactin and estradiol were not significant between before and after treatment (P ＞ 0.05).Conclusions:Zuogui pill is effective in treating oligoasthenospermia of kidney yin deficiency type.

Professor Li Haisong thinks that blood stasis occupies an important place in the pathogenesis and is the ultimate patho -logical trend of erectile dysfunction (ED).Blood stasis obstructing the collaterals is the pathological essence of ED .The author followed professor Li′s learning for a long time , summarized his experiences in treating ED based on the collaterals disease theory for dispersing blood stasis , and dredging collaterals should be basic treating principle throughout the whole process .And insect herbal medicine should be used to strengthen the action of dispersing blood stasis and dredging collaterals .Great importance should be attached to the pathological characteristics of liver depression and qi stagnation , and treating both mind and body is the key .

目的:初步评价蜂花前清方(蜂花前清茶)治疗慢性非细菌性前列腺炎的安全性和有效性.方法:采用随机对照方法将90名患者分为试验组和对照组,每组45例,进行为期10周的临床观察.试验组患者服用蜂花前清茶,2次/d,每次2袋;对照组患者口服特拉唑嗪,1次/d,每次1片.本研究以NIH-CPSI量表为主要评价指标来观察临床疗效.所有数据采用SPSS 19.0软件处理.结果:参照NIH-CPSI量表评分,两组患者总有效率依次为79.5％、41.5％,其差异具有统计学意义(P＜0.05).结论:蜂花前清方(蜂花前清荼)治疗慢性非细菌性前列腺炎在疼痛、排尿等方面有独特优势.

这天,北京中医药大学东直门医院男科门诊来了一位特殊的病人.为什么说特殊呢,是因为患者小李是被妻子给“强制”带来的.接诊的王彬医生问:“我能帮您什么吗?”他的妻子说:“王大夫,我家老爷们忒懒了,啥也不管,连每周一次的那个任务都不能完成,我问他是不是外边有人了,他说他没出轨,那您给看看他是不是有男科病.”王大夫支开了小李爱人,小李一脸委屈地说自己真没有外遇,只是最近一段身体特别累,一点欲望都没有,性生活也不像以前那样威猛,还有腰酸、乏力的症状,夜尿次数感觉也多了.平时性生活也不算频繁,想着是自己最近工作太累了,可能歇歇就会好,但是越休越累,用当下的流行语说就是“身体感觉被掏空”,这不,现在媳妇儿有意见了.

目的:观察“滑悦-A方”外用膏剂治疗早泄的临床疗效.方法:早泄患者随机分为两组,治疗组51例采用“滑悦-A方”外用膏剂治疗,对照组45例采用利多卡因胶浆外用治疗,均治疗4周.观察两组治疗前后早泄评分、中医疗效判定,比较两组疗效.结果:治疗4周后,治疗组总有效率78.43％,对照组总有效率57.78％.治疗组早泄评分、中医疗效的改善优于对照组(P＜0.05),结论:“滑悦-A方”外用膏剂治疗早泄的临床疗效明显优于利多卡因胶浆.

Objective To evaluate the clinical therapeutic effect of Tongluozhanshitang in treatment of erectile dysfunction. Methods 62 cases of control group were treated by Fufangxuanju capsule, 58 cases of treatment group were treated by Tongluozhanshitang, both for 4 weeks. The international index of erectile function (IIEF-5), score of mend sexual life quality questionnaire (mSLQQ), score of symptoms of Chinese medicine (SSCM) were compared between two groups before and after theatment. Results IIEF-5 and mSLQQ of two groups presented siginificant statistical differ-ence (P<0.01). Treatment group was superior to control group. The total effective rate was 82.7% in treatment group, 72.5% in control group. Conclusion Tongluozhanshitang in the treatment of ED has more obvious effectiveness and im-provement of life quality than Fufangxuanju capsule.

Male infertility is a common disease,with more and more patients caused by non -liquefied se-men in recent years.Professor Hai -song Li believed that semen non -liquefaction was mostly both deficiency and excess,including spleen and kidney deficiency,di resistance,liver blood stasis for the standard of disease.Taking Chinese medicine that strengthen spleen and tonify kidney,transform dampness and clear heat,soothing the liver and invigorate the circulation of blood,and topical suppository for patients with long course of disease,the curative effect is remarkable.

历来医家对阳痿病因病机多认为肾虚为主，治疗上也以温燥的补肾壮阳药为主。但临床发现效果往往不佳。早在战国初年《天下至道谈》中男性阳痿就有论述：“怒而不大者，肌不至也；大而不坚者，筋不至也；坚而不热者，气不至也。”这也是首次提到阳痿的发生与气的关系。在此基础上笔者团队提出了阳痿从气论治的观点，并强调要抓住先、后天的关系，着重于补脾气、舒肝气、温肾气来进行治疗。

Chronic prostatitis,especially prostate pain,is one of the common men’s diseases as well as one of andrology miscellaneous diseases.Although western medicine has multi -channel and multi -tools in the treatment areas,the clinical results are difficult to gain patients’satisfaction.Considering the rich experience in the treatment of prostate pain of Professor Li Haisong,the paper aims at introducing his experience in order to bring a new approach of treatment.

The etiology and pathogenesis of male diseases is different from previous etiology and pathogene-sis.Professor Li Haisong thinks the andrology disease has the characteristics of the kidney deficiency,liver depres-sion and stasis.During treatment,doctors should focus on the pathological characteristics and use "Wen,Shu, Huo"three -step treatment properly.Since Professor Li Haisongin has a lot experience on the treatment of male disease,the empirical analysis is shared through this article,hoping to bring out a new method of treatment.

目的:客观评价经会阴超声联合外用中药治疗慢性前列腺炎的临床有效性及安全性.方法:采用随机、对照的试验设计.共纳入符合诊断标准的慢性前列腺炎患者120例,使用随机数字表法将患者分为两组,均为60例.治疗组:经会阴超声联合中药外用治疗;对照组:单纯经会阴超声治疗.隔日治疗1次,每次10min,共7次.比较治疗后两组有效率,治疗前与治疗后组内、组间NIH-CPSI评分、中医证候评分量表(气滞血瘀证)积分变化情况,并记录治疗期间不良反应.结果:治疗组总有效率82.14％.对照组总有效率72.73％.两组总有效率比较,差异有统计学意义(P＜0.01).治疗2周后,两组NIH-CPSI各项评分分别与疗前对比,两组差异均显著(P＜0.01),有统计学意义;疗后两组间对比,治疗组疼痛不适评分、生活质量评分及NIH-CPSI评分总分明显优于对照组(P＜0.05),有统计学意义;两组排尿状况评分及症状影响评分,差异不显著(P＞0.05),无统计学意义.在中医症状方面,两组会阴坠胀疼痛、小腹坠胀疼痛、阴囊睾丸坠胀疼痛、腰骶酸软疼痛、排尿赤涩疼痛、尿有余沥、尿频等较之治疗前均显著改善(P＜0.01),而且疗后治疗组较之对照组在会阴坠胀疼痛、小腹坠胀疼痛、阴囊睾丸坠胀疼痛等方面改善更加明显,差异有统计学意义(P＜0.05).结论:经会阴超声可显著改善前列腺炎患者疼痛不适等症状,而且联合中药外用组较之单纯超声治疗效果更明显.

“三因制宜”是中医学中的重要治疗原则，其通过时间、人物、地域的不同，来指导临床用药。男科疾病在病因病机上也呈现出不同的特色，在治疗男科疾病时要因不同男科病种、体质、地域的特点进行辨证论治，可以更好的提高男科疾病的效果。课题组在临床中对男科疾病运用“三因制宜”辨证方法论治，收到比较满意的疗效。辨证与辨病相结合是提高男科疾病疗效的关键，同时宏观辨证与微观辨证相结合也是男科疾病治疗的一大方向。而将“三因制宜”的辨治理论机制进行探讨，以期为男科疾病的诊断与治疗提供新的思路与方法。