"一气周流"理论是黄元御医学学术思想的高度概括.认为中土为升降之枢轴,四象为轮,左升右降,循环往复,周流不息形成了一气周流的理论,同时将脏腑、气血、阴阳和情志纳入到此模型当中,对情志病的辨证论治具有启发性的作用.抑郁症属于中医中情志病的范畴,其发病多与脏腑、气机和情志等因素相关.治疗应运用培补中气、调畅气机、益精养神等方法,恢复机体枢轴的正常运行.

以明尼苏达工作适应论和USEM模型为基础,构建以外在核心能力、内在核心能力为主的大学生高质量就业能力综合评价指标体系.对吉林省2631名大学生的调研数据进行实证分析显示:大学生的就业能力处于中等水平,一些重要能力指标不尽如人意,学校人才培养模式以及自身工作经验、受教育程度等因素对大学生就业能力影响较大.并从就业导向、就业指导与服务体系、第一课堂和第二课堂建设等方面提出对策,为大学生高质量就业能力提升提供决策依据.

高考是人一生的重要转折点,2018年,参加全国高考的人数超过975万.我国视力障碍人群已超过1700万,每年参加"单考单招"接受高等教育的不超过300人.自2014年教育部面向视障者开放普通高考后,参加普通高考的盲人数量逐年增加,盲人考生成绩优秀的,被一些普通高校录取.这些视障大学生的融合能力、行动定向力以及视觉障碍带来的学习障碍等情况各不相同,高校应采取多种措施,全面而有效地支持视障人融入教学的各环节、享受校园生活,更好地接受高等教育.

针对盲人的心理和生理特点,探讨如何把推拿手法学和推拿功法学有机结合、把推拿专业的专业课学习与体育课教学有机结合、把推拿专业的理论课和实践课有机结合,从而提高盲人学生的实践技能.对于盲人按摩的从业者,专业技术水平和其临床治疗效果的提高,能够改善其工作生活状况,提高其收入水平和社会地位.

作为一门面向长春大学全校新生开设的公共基础课,"大学计算机基础"也为特殊教育学院的新生开设.本文以该课程对视障大学生的授课情况为出发点,调研和分析学生对计算机知识的掌握情况,并针对视障大学生的程序设计问题进行了深入探讨.

Based on the principle of human rights′freedom and equality, integrated education aims at providing equal access to educa-tion for people with disabilities. The goal is to open a door for special handicapped people to enter the mainstream society, get rid of the special mode of education, enable them to communicate with ordinary people, rationally use support resources to overcome their own obstacles and improve their individual ability for survival and education level, providing more possibilities for future life development.

Nowadays,the number of graduates in China shows increasing trend, employment becomes a focus that state and society pay attention to.And now the problem of the disabled is still a serious social one.Due to the statues of more job-seekers and fewer jobs, the employment for the disabled people is difficult, which brings influences for their living and psychology.Based on analyzing the problems existing in the employment for disabled persons, this paper gives some solutions according to the current policies.

TOAST typing, acknowledged by the world, is an etiology classification standard widely used in ischemic stroke , which is not only a kind of etiology classification method, but also closely related to patients′risk classification, treatment and prognosis, so it is of wide and important clinical value to explore the biological indexes related to typing .This paper analyzes the correlation between plasma biological parameters and TOAST typing,hoping to provide references for checking the causes and prevention of individual ischemic en -cephalopathy.

"大众创业""草根创业"的观点对于中国经济的发展和进步非常关键. 视障大学生为了更好地融入社会,自然也面临着创新创业这一时代主旋律. 创新创业是他们改善生活状况、融入社会、实现人生价值的主要途径.但是在创新创业中,存在很多制约因素,需要我们尽快找到解决这些难题的有效办法,使他们更好地融入社会,提高生存质量.

目的 探讨黄芪颗粒对病毒性心肌炎患儿血清中肿瘤坏死因子-α(TNF-α)、白细胞介素-2(IL-2)和白细胞介素-10(IL-10)的影响.方法 选取来医院就诊的46例病毒性心肌炎患儿分为常规治疗组和黄芪颗粒治疗组各23例,14天为1个疗程,治疗28天;同时选取10例健康儿童作为对照组.采用酶联免疫法检测各组患儿血清中TNF-α、IL-2和IL-10的蛋白含量.结果 治疗前与对照组相比较,常规治疗和黄芪颗粒治疗组患儿血清中IL-10的蛋白含量明显降低,IL-2、TNF-α的蛋白含量明显升高,差异有统计学意义(P＜0.01).治疗后与治疗前相比较,两组患儿血清中IL-10的蛋白含量升高,IL-2、TNF-α的蛋白含量降低,差异均有统计学意义(P＜0.01);且黄芪颗粒治疗组效果优于常规治疗组,差异有统计学意义(P＜0.05).结论 黄芪颗粒能通过降低患儿血清中IL-2、TNF-α的蛋白含量和上调IL-10的蛋白含量抑制病毒性心肌炎的病程,其作用机制有待于进一步探讨.

股骨粗隆间骨折好发于老年患者，且患者往往合并多种内科疾病，体质较差。对于这类骨折，手术治疗已经被骨科医生及患者所接受，手术方法有髓外的钉板系统及髓内固定装置，如股骨近端髓内钉（ PFN）、股骨近端防旋髓内钉（ PFNA）、Gam－ma钉、亚洲髋螺钉（ IMHS）及新一代髓内钉InterTan系统〔1〕，本文回顾性分析使用InterTan治疗老年股骨粗隆间骨折患者的疗效。

60 cases of patients with hysteromyoma were randomly divided into acupuncture and massage therapy group, drug treatment control group 1 and blank control group 2. Dredging menstruation method and drug treatment method were given to the treatment group and the control groups. After three courses, we observed the clinical efficacy of the three groups, the cure rate of acupuncture and mas-sage therapy group was 20% and the effective rate was 95%;the cure rate of drug treatment group was 10% and the total effective rate was 80%, showing that the total effective rate of the treatment group was higher than that of the control group. The treatment of hystero-myoma with the method of acupuncture and massage had a significant effect and no medication side effects, which was safe and easy to do.

盲人因其触觉敏感等生理特点,学习按摩技术完全可以达到要求,在此方面优于常人盲人从事按摩,既是自食其力,又是其平等参与社会、自我价值实现的体现,所以按摩是盲人最适合的职业,而且视障高等教育的主要专业——盲人按摩专业,也更受视障学生的欢迎.在总结教学经验的基础上,根据盲人毕业生的工作性质、就业情况、按摩行业发展情况及技术要求,笔者认为在盲人按摩教学过程中,应采取以因材施教为主,同时注重理论学习、功法训练、强制重复训练等教学方法,以取得良好的教学效果.

目的：探讨阿托伐他汀对老年自身免疫性脑脊髓膜炎（EAE）大鼠脑白质髓鞘碱性蛋白（MBP）和少突胶质细胞转录因子（OLIG）1蛋白表达的影响。方法取老年 Wistar 雄性大鼠80只，随机分为对照组、模型组、阿托伐他汀大剂量组（8 mg／kg 组）和阿托伐他汀小剂量组（2 mg／kg组），每组20只。采用新鲜豚鼠50％全脊髓匀浆液和完全弗氏佐剂（CFA）免疫制备EAE模型，免疫后第2天开始，模型组给予生理盐水灌胃，阿托伐他汀组给予阿托伐他汀不同剂量灌胃，持续灌胃21 d，于第22天处死，取脑干和脊髓待测。采用实时荧光定量和免疫组织化学染色检测各组脑干、脊髓中MBP和OLIG1的mRNA水平和蛋白阳性表达强度。结果与对照组比较，模型组 MBP mRNA水平和蛋白阳性表达强度明显升高、OLIG1明显降低（P＜0．01）；阿托伐他汀小剂量组MBP mRNA水平和蛋白阳性表达强度升高、OLIG1降低（P＜0．01）；阿托伐他汀大剂量组 MBP mRNA水平和蛋白阳性表达强度略升高、OLIG1略降低，无显著差异（P＞0．05），模型组、阿托伐他汀大、小剂量组差异显著（P＜0．01）。结论阿托伐他汀能够通过下调MBP、上调OLIG1 mRNA水平和蛋白阳性表达强度，对EAE大鼠的脑白质髓鞘损伤具有保护作用，且大剂量作用优于小剂量。

目的 探讨黄芪颗粒对病毒性心肌炎患儿外周血中T细胞亚群及免疫球蛋白的影响.方法 选取46例病毒性心肌炎患儿随机分为常规治疗组和黄芪颗粒治疗组各23例,14 d为1个疗程,治疗28天;同时选取10例健康儿童作为对照组.采用贝克曼流式细胞仪检测C D3+、CD4+、CD8+,免疫比浊法于全自动生化仪上测定IgA、IgG、IgM.结果 治疗前与对照组相比较,病毒性心肌炎患儿血清CD3+、CD4+、CD4+/CD8+比值明显降低,CD8+明显升高,IgG、IgM明显升高,差异均有统计学意义(P<0.01);IgA无明显变化(P>0.05).治疗后与治疗前相比较,患儿血清中CD3+、CD4+、CD4+/CD8+比值明显升高,CD8+明显降低,IgG、IgM明显降低,且黄芪颗粒治疗组效果优于常规治疗组,差异均有统计学意义(P<0.05);IgA无明显变化(P>0.05).结论 黄芪颗粒能通过调节机体细胞免疫和体液免疫指标,改善病毒性心肌炎患儿症状,起到治疗作用.

Blind persons as the most difficult group in vulnerable groups with disabilities, whose employment channels are narrow and have difficulties. Massage is the best way for the blind to get rid of their predicament, also is an important channel for their entrepre-neurship and employment. But blind masseurs are in the condition of big working and life pressure, lacking of social security, poor health, as well as big operating pressure and low efficiency of massage agencies. Based on the survey and investigation, this research gives some measures on the effective improvement of the management level of blind massage industry and points out that the government should take responsibilities of support, guidance, supervision, coordination, guidance and protection in the process of blind massage industry development, so as to promote its healthy and ordered development.

目的:通过观察妊娠期高血压患者胎盘中IL-2和MMP-9的表达水平探讨妊娠期高血压疾病的发病机制.方法:选择妊娠期高血压孕妇114例,其中38例为轻度、35例为中度、41例为重度;另选择20例正常孕妇作为对照组,4组均于胎盘娩出后立即在胎盘脐带的对侧剪取胎盘组织,采用实时荧光定量PCR方法和酶联免疫法检测胎盘组织中IL-2和MMP-9的mRNA水平和蛋白含量.结果:轻度组孕妇与对照组孕妇胎盘组织中IL-2、MMP-9的mRNA水平及蛋白含量比较差异无统计学意义(P＞0.05);中、重度组孕妇MMP-9的mRNA水平及蛋白含量均低于对照组孕妇,IL-2的mRNA水平及蛋白含量均高于对照组孕妇,差异均有统计学意义(P＜0.01).结论:妊娠期高血压孕妇胎盘组织中IL-2、MMP-9的mRNA水平及蛋白含量随着分级增高而变化,为临床治疗妊娠期高血压疾病提供新的靶点.

高血压脑出血是老年患者致死致残的主要疾病，其中重型脑室出血死亡率及致残率极高。老年重型脑室出血内科保守治疗和传统的单纯脑室外引流效果不佳。我科对2010年1月至2012年12月收治的43例老年重型脑室出血的患者行脑室外引流与腰大池引流序贯治疗，临床效果较好，现报道如下。

Traditional Chinese massage is a mature occupation for the blind. In recent years,with the rapid development of the blind massage service trade in our country,the blind massage training rises and total employment rate grows rapidly in Jilin Province. Besides industry management and policy support,the development of blind massage service trade depends on blind masseuses' technology level. The differences of masseuses' licensed technical level are obvious because of their physiological and psychological characteristics,learning habits,educational background,working nature and so on. Therefore,it is of great significance to strengthen training and continuing education for blind masseuses.

丘脑出血临床上比较常见，占高血压脑出血的10％～15％。由于丘脑解剖及功能的特殊性，出血后死亡率及致残率极高。老年患者由于神经功能可塑性差，且常合并其他系统疾病，死亡率及致残率更高。目前对于丘脑出血无规范的治疗方案，手术适应证及术式的选择也没有统一的标准。如何提高治疗效果、改善患者预后一直是神经外科探讨的热点。本文对26例重型内侧型老年丘脑出血患者尝试去骨瓣减压联合血肿腔置管引流，取得了较好的疗效。