目的:观察在老年慢阻肺的护理干预中实施心理干预对负面情绪以及临床效果的影响.方法:从该院2020.5-2022.5月期间选取60例患者,随机将其分为观察以及对照组,各30例,对照组(常规护理),观察组(心理干预),观察两组患者的临床效果以及负面情绪.结果:观察组SDS、SAS评分低于对照组;护理质量高于对照组;护理满意度高于对照组;生活质量高于对照组;住院时间以及PaCO2低于对照组,PaO2高于对照组;睡眠质量高于对照组,(P＜0.05).结论:此次研究对老年慢阻肺患者实施心理护理干预,能够进一步提升患者的护理满意度降低其不良情绪,确保治疗以及护理概念能够顺利实施,缩短患者的住院时间提升其肺部功能,建议推广.

Objective To explore the value of traditional Chinese medicine acupoint application combined with emotional nursing intervention in functional constipation. Methods From March 2020 to June 2021, a total of 68 patients from Department of Respiratory Medicine, People’s Hospital Affiliated t o Fujian University of Traditional Chinese Medicine with functional constipation were randomly divided into the control group（receiving conventional treatment） and the study group（receiving TCM acupoint application combined with emotional nursing intervention on the basis of the control group）. The observation indicators of two grous of: efficacy, score of constipation symptoms, Hamilton agitation scale（SAS） and Hamilton self-rating depression scale, SDS), gastrointestinal hormones and enterodynamics indexes, quality of life scale for constipation patients（PAC-QOL）. Results The total effective rate of the study group（94.12%） was significantly higher than that of the control group（73.53%）（P ＜ 0.05）. Before treatment, there was no significant difference in the scores of constipation symptoms between the two groups（P ＞ 0.05）. After treatment, the decrease of scores of constipation symptoms in the study group was significantly lower than that in the control group（P ＜ 0.05）. There were no significant differences in SAS and SDS scores between the two groups before treatment（P ＞ 0.05）. After treatment, the decrease of these SAS.SDS scores in the study group was significantly lower than that in the control group（P ＜ 0.05）. Before treatment, there were no significant differences in gastrointestinal hormone and intestinal dynamics indexes between the two groups（P ＞ 0.05）. After treatment, somatostatin, maximum rectal volume sensory threshold, maximum rectal shrinkage pressure and simulated defecation anal pressure indexes in the study group were significantly lower than those in the control group, while substance P and motilin indexes were significantly higher than those in the control group（P ＜ 0.05）. There was no significant difference in PACQOL scores between the two groups before treatment（P ＞ 0.05）. The decrease of PAC-QOL in the treatment group was significantly lower than that in the control group（P ＜ 0.05）). Conclusion The application of traditional Chinese medicine acupoint application combined with emotional nursing intervention can enhance the therapeutic effect of functional constipation, significantly improve the clinical symptoms and negative emotions of patients, optimize gastrointestinal hormones and intestinal dynamics, and improve the quality of life.

目的 探讨经皮穴位电刺激对脑卒中后假性球麻痹患者吞咽功能的影响. 方法 采用随机数字表法将60例脑卒中后假性球麻痹吞咽功能障碍患者分为对照组和试验组,每组各30例.2组均采用吞咽康复训练,试验组在此基础上给予经皮穴位电刺激,每日1次,每次20 min,连续干预10d.观察2组干预前后洼田饮水试验评级分布情况及标准吞咽功能评估(SSA)评分变化,并比较其疗效. 结果 与对照组比较,试验组治疗后吞咽功能评级和SSA评分均明显改善(P＜0.05);试验组疗效优于对照组(P＜0.05). 结论 经皮穴位电刺激能够一定程度上改善脑卒中后假性球麻痹吞咽障碍患者的吞咽功能.

目的 观察五行音乐疗法联合耳穴埋豆对慢性阻塞性肺疾病(COPD)失眠患者的护理疗效.方法 将90位慢性阻塞性肺疾病失眠患者分为三组:A组给予常规护理+五行音乐疗法治疗;B组给予常规护理+耳穴埋豆;C组给予常规护理+五行音乐+耳穴埋豆疗法治疗.结果 治疗前三组患者的匹兹堡睡眠质量指数问卷评分比较差异无统计学意义(P>0.05),治疗后C组患者的匹兹堡睡眠质量指数问卷评分低于A、B组患者(P<0.05).结论 中医五行音乐疗法联合耳穴埋豆治疗慢性阻塞性肺疾病失眠,护理疗效满意,为临床提供了有效的改善失眠的方法.

目的 观察生物陶瓷穴位热敷对慢性咳嗽风寒袭肺证患者的生活质量的影响.方法 对照组采用常规治疗护理方法,实验组在对照组的基础上将生物陶瓷热敷袋置于恒温箱中加热一定时间后,作用于患者膻中、大椎及肺俞等穴.采用莱斯特咳嗽生活质量量表(LCQ-评分越高,咳嗽程度越轻,生活质量越好)对两组患者治疗后的生活质量进行分析.结果 实验组患者LCQ咳嗽生活质量问卷各项目评分均高于对照组患者,差异具有统计学意义(P<0.01).结论 生物陶瓷穴位热敷对提高成人慢性咳嗽风寒袭肺证生活质量具有较好的疗效.

目的 探讨生物陶瓷热敷袋穴位热敷治疗成人慢性咳嗽风寒袭肺证患者的临床疗效研究.方法 选择2015年5月—2017年12月在本院肺病科住院的慢性咳嗽风寒袭肺证患者120例作为研究对象,按随机数字列表法随机分为热敷组和对照组两组,每组各60例.两组患者在入院后均采用常规护理,热敷组在此基础上加穴位生物陶瓷热敷袋治疗(膻中穴、大椎、双侧肺俞穴).评估治疗前后咳嗽积分、中医证候积分及总有效率.结果 两组治疗后日间症状评分及夜间症状评分均低于本组治疗前(P<0.05),且热敷组治疗后改善程度大于对照组(P<0.05);治疗后热敷组中医证候积分改善度大于对照组,差异有统计学意义(P<0.05);热敷组治疗总有效率大于对照组,差异有统计学意义(P<0.05).结论 生物陶瓷热敷袋穴位治疗可减轻成人慢性咳嗽患者咳嗽程度,提高生活质量并减轻中医症状,且安全有效,值得临床上推广.

目的 运用经皮穴位电刺激结合常规康复训练的方法对脑卒中后单侧空间忽略患者进行干预,探讨经皮穴位电刺激对单侧空间忽略患者的康复作用,为单侧空间忽略康复治疗提供一种安全、有效、简便的新方法.方法 将2016年9月—2017年5月福建中医药大学附属人民医院脑病科及康复科脑卒中后单侧空间忽略的60例患者,按随机数字表法将所有患者分为实验组和对照组,各30例.两组均行常规治疗、康复训练、护理指导,实验组在此基础上给予大椎、至阳、命门、长强四个穴位的经皮穴位电刺激.于试验开始时、一周后、两周后,根据线段二等分实验、Barthel指数评定量表(Barthel Index,BI)分别进行康复效果的评定.结果 分别收集干预一周后、两周后的数据,实验组患者的日常生活活动能力、对空间忽略的改善程度,经过分析后得出,以上指标均有所改善,差异具有统计学意义(P<0.05).结论 经皮穴位电刺激配合传统的康复训练能有效提升脑卒中后单侧空间忽略患者的生活自理能力,可在临床上推广应用.

目的:探讨徴调音乐对脑卒中运动性失语气虚血瘀证患者语言功能及脑血流的影响.方法:将符合条件的82例患者按随机数字表法分为微调音乐组、西洋音乐组和空白对照组,3组均接受常规治疗和护理,徵调音乐组配合聆听微调音乐,西洋音乐组配以聆听西洋音乐.观察患者语言功能和大脑动脉血流速度.结果:徴调音乐组语言功能明显优于其他2组,音乐干预2组患者左侧大脑中动脉平均血流速度较试验前均显著提高,试验后徴调音乐组左侧大脑前动脉、中动脉平均血流速度较空白对照组明显提高.结论:徵调音乐干预可有效改善脑卒中运动性失语患者的语言功能和脑血流灌注.

雾化吸入是用雾化装置将药液分散成细小的雾粒,通过鼻或口吸入,沉积于呼吸道和(或)肺部的给药方法,是呼吸科一项重要治疗手段.通过雾化给药,可以达到缓解支气管痉挛、稀化痰液、防治呼吸道感染等作用,尤其适应于气流受限疾病,如AECOPD和哮喘急性发作.由于它直接作用于靶器官,因此药物起效快、用药量少、局部药物浓度高而全身不良反应少等优点.不足之处是雾化型药物费用较贵,雾化器有动力要求而携带不方便.

Objective:To explore the effect of the tune of zhi on language function and neural function in Broca's aphasia stroke patients with qi deficiency and blood stasis syndrome. Method:Fifty-five patients were randomly divided into the tune of zhi group and control group. The tune of zhi group accepted routine treatment as well as nursing and listened the tune of zhi,once a day,30min per time,5 times a week, continuously for 12 weeks.Control group accepted routine treatment and nursing only.Before and after intervention, Chinese rehabilitation research centre standard aphasia examination(CRRCAE) and clinic neurological deficit scale were used to evaluate the language function and neural function defect respectively. Result:In language function: After intervention there were significant improvements of correct answer rates of comprehension repeating speaking, phonation, reading, transcribing, dipiction, dectation and count of CRRCAE in the tune of zhi group compared to before intervention(P0.05).In control group, after intervention there were significount improvements of correct answer rates of comprehension, repeating,speaking,phonation of CRRCAE compared to before(P0.05).The comparison between two groups after intervention, except reading, the improvements of correct answer rates of 8 aspects of CRRCAE in the tune of zhi group were significant better than those of control group(P0.05).In neural function defect: After intervention, the score in the tune of zhi group decreased signifi-cantly compared to before intervention(P0.05),and decreased significantly compared to control group(P0.05). Conclusion:The tune of zhi music can improve the language function in Broca's aphasia stroke patients with qi deficiency and blood stasis syndrome,and promote patients' nervous function recovery effectively.

Objective: To observe the effect of tune of Zhi with suggestion therapy on left middle cerebral artery blood flow and neural function of patients with Broca's aphasia after stroke. Methods: 90 patients with Broca's aphasia after stroke were randomly divided into tune of Zhi with suggestion therapy group(A group),tune of Zhi group(B group),and control group(C group). Three groups accepted general treatment and nursing. On the basis of that,B group listened the tune of Zhi,once a day,30 min per time,5 times a week,for 12 weeks.A group listened tune of Zhi and at the same time accepted suggestion therapy. Before and after intervention,mean blood velocity(Vm) of left middle cerebral artery(MCA) of all patients were measured by Transcranial Doppler(TCD) to evaluate the neural function defect. Results: In aspect of Vm of MCA: A group and B group had remarkable improvement after intervention compared with before(P 0.05);of three groups after intervention,the Vm of MCA improved obviously in A group and B group compared with C group(P 0.01);Vm of MCA improved obviously in A group compared with B group(P 0.01). In aspect of neural function defect scores:after intervention,the scores in A group and B group decreased significantly compared with before(P 0.05);of three groups after intervention,the scores in A group and B group decreased significantly compared with C group(P 0.01);the score increased obviously in A group compared with B group(P 0.01). Conclusion: The tune of Zhi with suggestion therapy can quicken the mean blood velocity of left middle cerebral artery of patients with Broca's aphasia after stroke and decrease the score of neural function defect,which will contribute to the recovery of language expression and nervous system.

Objective To evaluate the reliability and validity of the Chinese-version Stroke and Aphasia Quality of Life Scale(SAQOL-39g).Method The reliability and validity of SAQOL-39g was tested in 121 patients with stroke and aphasia.Results The content validity index for the scale was 0.92.Three factors were extracted by principal components analysis,which contributed 54.00% of the variance.The Cronbach's α was 0.94 for the total scale and the test-retest correlation was 0.97.Conclusion The Chinese-version of Stroke and Aphasia Quality of Life Scale has good psychometric quality and can be used as a measurement tool for the quality of life in Chinese patients with stroke and aphasia.

目的 探讨中医护理干预对肛肠科术后排便的影响.方法 将66例肛肠术后便秘病人随机分为观察组和对照组,每组33例,对照组进行常规护理,观察组在常规护理基础上进行中医辨证施护.结果 观察组总有效率为91.0%,对照组为66.67%,观察组明显优于对照组(P＜0.05).结论 常规护理配合中医辨证施护,能有效消除便秘发生.减轻患者痛苦和不适,促进切口早期愈合.

脑卒中病人由于其自身的特点,是医院感染的易感者,其医院感染发病率高达37.3%,感染部位以下呼吸道为首位[1].下呼吸道感染又直接影响着病人的预后.我们对206例脑卒中病人进行了早期护理干预,并拟订出预防下呼吸道感染的护理措施.现报告如下.

Objective To explore the role of CD4~+CD25~+CD127~(lo) regulatory T cells (Tregs) and inter-leukin (IL)-6, transforming growth factor beta (TGF-β), IL-17 in the pathogenesis of lupus nephritis (LN) by detecting the levels of IL-10, IL-6, TGF-β, IL-17, CD4~+CD25~+CD127~(lo) Tregs in the peripheral blood of patients with active and inactive LN. Methods Three-colour flow cytometry was used to quantitatively measure proportions of Treg cells, the levels of TGF-β, IL-17 were detected by ELISA, and the levels of IL-10, IL-6 in the peripheral blood were detected by Cytometric Bead Array System. Results ① Compared with the inactive LN and the normal controls (P<0.01), the level of CD4~+CD25~+CD127~(lo) Tregs from patients with active LN was lower(P<0.01). When compared with the normal controls, the level of CD4~+CD25~+CD127~(lo) Tregs from LN inactive patients had no significant difference (P>0.05). ② Compared with patients with inactive LN, the levels of IL-10, IL-6 was higher (P<0.01) in patients with active LN. ③ Compared with the patients with inactive LN and the normal controls, the levels of TGF-β, IL-17 was not significantly different (P>0.05). ④ The level of CD4~+CD25~+CD127~(lo) T cell was correlated negatively with the levels of IL-10, IL-6 and SLEDAI (P<0.05), and was not correlated with C3 and C4. ⑤ SLEDAI was correlated positively with the levels of IL-10 and IL-6 (P<0.01). SLEDAI and the level of IL-10 were correlated negatively with C3 and C4 (P<0.01 for both). ⑥ The level of CD4~+CD25~+CD127~(lo) Tregs from LN was not correlated with TGF-β and IL-17. ⑦ TGF-β was correlated positively with the level of IL-17. Conclusion ① The level changes of Tregs and IL-10, IL-6, TGF-β in the peripheral blood of LN can be used as the indicators for the activity status of lupus nephritis. ② Tregs and IL-10, IL-6 in the peripheral blood of LN patients is negatively correlated. ③ The glucocorticoid hormone is helpful to elevate the level of Tregs but decrease IL-17. T cell level can vary in different body status, different microenvironmental and immune status.

目的:探讨活动期和静止期狼疮性肾炎(LN)患者外周血中调节性T细胞CD4+CD25+CD127lo(Treg)变化的意义.方法:流式蛋白分析系统(CBA)测定外周血IL-6、IL-10水平,流式细胞仪测定外周血CD19+CD69、CD19+凋亡率、Tregs水平.结果:(1)①LN患者CD19+CD69+、CD19+凋亡率水平较正常组升高(P<0.01);②活动期LN CD4+、CD4+CD25+CD127lo水平较正常组降低(P<0.01);静止期CD4+、CD4+CD25+CD127lo与正常组比较差异无统计学意义;③活动期LN患者IL-10、IL-6、CD19+CD69+、CD19+凋亡率水平较静止期显著升高(P<0.01).(2)Treg与CD19+CD69+、CD19+凋亡率无相关性,与IL-10、IL-6呈负相关(P<0.05),与ds-DNA、SLEDAI呈负相关(P<0.01).CD19+凋亡率与IL-10呈负相关(P<0.01),与SLEDAI、CD19+CD69+呈正相关(P<0.01).结论:Treg可作为狼疮活动性的指标,并能够减少或完全抑制自身抗体的产生.

目的 探讨CO2激光治疗痔疮患者的护理.方法 总结48例痔疮患者行CO2激光治疗的术前术中术后护理.结果 经过给予针对性的护理后,48例患者全部痊愈,随访半年,未见复发.结论 术前充分做好心理护理和必要的检查,术中积极配合医生并密切观察生命体征,术后做好饮食指导、肛周局部护理、创面换药护理、并发症的观察及处理,指导患者养成良好的生活健康习惯,对提高手术治愈率具有重要意义.

目的 探讨活动期和静止期狼疮性肾炎患者外周血中CD4+CD25+CD127b调节性T细胞水平、IL-17、IL-6水平与中医证型之间的关系. 方法 用流式细胞仪三色荧光标记法检测外周血调节性T细胞,酶联免疫吸附法测定外周血中IL-17,CBA流式蛋白分析系统检测外周血中IL-6. 结果 狼疮性肾炎患者调节性T细胞水平热毒炽盛型低于阴虚内热型(P＜0.01),外周血IL-6水平热毒炽盛型高于阴虚内热型(P＜0.01). 结论 热毒介导了狼疮性肾炎患者CD4+T细胞的分化,使得CD4+T细胞向IL-17转化.