探究基于经阴道彩超血流显像的子宫肌瘤诊断分析以及评价高强度聚焦超声(HIFU)治疗疗效为主要目的.以133例疑似子宫肌瘤的女性患者作为研究对象,55例确诊的女性患者作为观察组,其余78例健康人群作为对照组.对观察组患者进行经阴道彩超血流显像来观察患者的舒张末期血流速度(ED)、收缩期峰值血流速度(PS)、阻力指数(RI),以及血流参数与疾病严重程度的相关性.研究结果发现,与对照组相比,观察组患者ED、PS、RI较高(P＜0.05);轻度患者ED、PS、RI低于中重度患者(P＜0.05);与ED、PS、RI单一参数诊断相比,联合诊断对子宫肌瘤诊断敏感度和准确度均较高(P＜0.05);与HIFU治疗后1个月相比,治疗后3个月、6个月瘤体直径均缩小(P＜0.05),治疗总有效率为96.36％.阴道彩超血流显像对子宫肌瘤患者诊断价值较高,经HIFU治疗后,患者肌瘤直径明显缩小,临床效果较为显著.

目的 应用乳腺影像报告和数据系统(BI-RADS)分级标准,对超声图像特征进行标准处理,建立Logistic回归模型,探讨高频彩色多普勒超声在鉴别乳腺良、恶性肿块中的诊断价值.方法 回顾性分析深圳市罗湖区妇幼保健院2017年1月-2018年8月经乳腺活体组织检查或手术的200例患者共计239个肿块的乳腺超声图文资料,对超声图像特征进行单因素分析以及建立非条件性Logistic回归模型,总结乳腺肿块的超声特征,提出良、恶性肿块超声鉴别诊断要点.结果 单因素分析结果显示,形态、边界、微钙化、血流、腋窝淋巴结异常、后方回声等超声图像特征对鉴别乳腺良(恶)性疾病有统计学意义(P＜0.001),而Logistic回归方程只保留了毛刺或蟹足状形态和微钙化两个因素.结论 高频彩色多普勒超声对良(恶)性乳腺肿块有着较高的鉴别效能.其操作简单,对人体无伤害,是临床早期诊断乳腺肿瘤的首选检查方法.

目的 观察对于妇科急腹症患者采用阴式超声联合腹式超声联合检查的诊断价值意义分析.方法 共收集139例从2016年12月至2017年12月于本院收治的妇科急腹症患者,依照患者接受辅助检查方式分成两组,其中仅接受腹式超声检查者78例称为对照组,另接受腹式超声联合阴式超声检查者61例称为联合组.将计算两组临床诊断准确率、误诊率、漏诊率,并分析妇科急腹症的超声特点.结果 联合组诊断准确率高达96.72％,误诊与漏诊率均为1.64％,而对照组诊断准确率为79.50％,漏诊、误诊率均为10.25％.差异具有统计学意义(P＜0.05).结论 对于妇科急腹症患者采用阴式联合腹式超声检查,可获得较高的临床诊断率.

目的:观察前置胎盘孕妇产前采用超声评估预测其产时大出血的临床价值分析.方法 :选择某院2016年3月～2017年3月收治的经产前超声诊断为前置胎盘患者共计71例进行分组,其中26例(36.62％)出现产前大出血称为出血组,另45例(63.38％)安全生产称为对照组.分析两组超声检查异常之处,并分析超声检查前置胎盘产时大出血的危险因素.结果 :出血组患者年龄、流产次数、分娩次数、子宫手术史均高于对照组,差异具有统计学意义(P<0.001);出血组超声检查胎盘为中央型、附着于前壁、距宫颈内口<2cm、胎盘植入、缺损率明显高于对照组,差异具有统计学意义(P<0.001).结论 :高龄产妇、多次流产、子宫手术史均为发生前置胎盘高危基本因素,行超声检查时应详细查看是否存在胎盘为主要附着前壁、缺损、植入、中央前置型、距宫颈口距离<2cm超声学特征的高危出血倾向.

Objective To investigate the clinical value of fetal blood flow measurement in predicting perinatal outcome of fetuses with intrauterine growth restriction. Methods According to random number table method, 50 pregnant women with fetal growth restriction were selected as case group, and at the same time, 50 normal pregnant women were selected as control group. The fetal umbilical artery, middle cerebral artery and renal artery in pregnant women were detected by color ultrasound Doppler. Results The umbilical artery blood flow of FGR end systolic peak value and the end-diastolic peak ratio S/D, middle cerebral artery blood flow S/D, the prevalence of abnormal renal artery blood flow S/D ratio in the case group were obviously higher than those in the control group, and the differences were significant (P<0.05). The umbilical artery blood flow S/D in the fetus with abnormal hemodynamics in FGR was negatively correlated with the S/D ratio in the middle cerebral artery blood flow(r=-5.325, P<0.05), and it was positively correlated with the S/D ratio in the renal artery blood flow(r=7.325, P<0.05). The incidences of mild asphyxia and severe asphyxia in the case group were significantly higher than that in the control group, and the differences were significant (P<0.05). Conclusions The combined detection of limited growth of fetal umbilical artery, middle cerebral artery and renal artery hemodynamics indexes, help evaluate the fetus-placental circulation and fetal brain and kidney blood circulation situation at the first time, accomplish early detection and early treatment of abnormal cases, to guide clinical termination time, and improve the perinatal outcomes. Key words: Growth restriction; Umbilical artery; Middle cerebral artery; Renal artery

目的 通过了解乳腺癌患者的生长激素、胰岛素样生长因子-1水平,探讨胰岛素样生长因子-1与乳腺癌的关系.方法 采用病例对照研究,以年龄进行1∶1配比乳腺癌患者和对照组各197例,分析两组一般情况、生长激素、胰岛素样生长因子-1水平与乳腺癌发生的关系.结果 生长激素水平比较差异无统计学意义(P＞0.05);50岁以下女性胰岛素样生长因子-1病例组与对照组比较差异有统计学意义(P＜0.01),50岁以上组比较差异无统计学意义(P＞0.01);用1∶1匹配条件Logistic回归分析显示,β =0.137,OR=1.147(P ＜0.01).结论 胰岛素样生长因子-1水平增高是乳腺癌的危险因素,可作为乳腺癌筛查的指标之一.

Objective To provide reference basis for effectively reducing perinatal mortality by analyzing the change trend and influencing factors of perinatal death in Luohu District of Shenzhen city from 2006 to 2015.Methods The monitoring data of perinatal death in Luohu District of Shenzhen city from 2006 to 2015 was collected,trend x2 test was used to analyze the change trend and influencing factors of perinatal death.Results From 2006 to 2015,the mean perinatal mortality in Luohu District was 7.01‰,and the mean perinatal mortalities among resident population and floating population were 4.80‰ and 10.86‰,respectively.The perinatal mortality showed a decreasing trend (x2trend =177.178,P=0.000),the first cause of perinatal death was birth defects (2.20‰).Conclusion From 2006 to 2015,the perinatal mortality showed a decreasing trend in Luohu District,and birth defects ranked the first place of perinatal death.To effectively reduce perinatal mortality,antenatal care and consciousness of prenatal examination should befurther improved,management of floating population should be enhanced,and the diagnostic level of medical staff should be improved.

目的 探讨乳腺癌的相关危险因素.方法 选取乳腺癌患者204例,健康体检者648例,调查乳腺癌患者与健康体检者的一般情况、病史、月经生育史及用药情况等,采用单因素和多因素Logistic回归分析进行统计分析.结果 多因素统计分析结果提示,职业、文化程度、痛经、定期乳腺检查、良性乳腺病史为乳腺癌的相关影响因素,其中职业为事业单位职员、文化程度高中及以下、定期乳腺检查为乳腺癌的保护因素.结论 女性乳腺癌的发生是受多种因素影响的结果,预防乳腺癌应从多因素、多途径考虑,做到早发现、早诊断、早治疗,从而提高女性健康水平及生活质量.

目的 分析2006-2015年深圳市罗湖区围产儿死亡情况,为进一步降低深圳市罗湖区围产儿死亡率提供科学依据.方法 对2006-2015年深圳市罗湖区围产儿死亡监测资料进行统计分析.结果 2006-2015年罗湖区年平均围产儿死亡率为7.01‰,其中常住人口10年平均围产儿死亡率为4.78‰,流动人口为10.86‰.十年间罗湖区围产儿死亡死因顺位前3位为出生缺陷(31.8％)、原因不明(27.5％)、胎儿因素(11.5％).十年间死胎导致的围产儿死亡率最高.结论 2006-2015年罗湖区平均围产儿死亡率较低,但仍需进一步加大对婚检及孕检的健康教育宣传力度,加强围产期保健及流动人口管理,提高孕产妇孕期保健意识.

Objective:To discuss the influence of systemic psychological nursing on time of operation and negative emotion of the patients of minute breast le -sion resection via wire -localization guided by ultrasound.Methods:Selected 60 cases of patients with minute breast lesions showing negative and abnormal imaging findings clinically diagnosed in the period from February 2015 to May 2016 were selected and equally divided into observation group and control group at random, and all patients received breast lesion puncturing resection via wire -localization guided by ultrasound.The, the patients in the observa-tion group received the routine nursing combined with systemic psychological nursing , and the patients in the control group received routine nursing.Punc-ture and resection success rate was statistically analyzed, and the two groups were analyzed and compared in operation time, and also the patients’ negative emotion was investigated by use of visual analogue scale(VAS), self -rating anxiety scale(SAS) of Zung, and symptom checklist(SCL -90 ).Results:The patients from observation group all completed puncture surgery in one time, and the observation group had a higher resection than the control group, but the difference was not statistically significant (P >0.05); the observation group had a shorter operation time than the control group (P <0.05); and the observation was superior to the control group in scoring of VAS, SAS and SCL -90 after operation.Conclusion: Through the combination of systemic psy-chological nursing and minute breast lesion resection via wire -localization guided by ultrasound, the negative emotion of patients could be effectively eased, the puncturing resection could be completed smoothly, and the operation time could be shortened, so it was worthy of application in clinical practice.