目的:探讨四妙勇安汤对糖尿病足治疗效果的影响.方法:选择2017年10月至2019年10月期间在本院治疗的82例糖尿病足患者,根据治疗方式分为对照组(40例)和四妙勇安组(42例).对照组常规西药治疗及饮食控制,四妙勇安组增加四妙勇安汤内服治疗,对比两组治疗后糖尿病足Wagner分级改善情况.结果:四妙勇安组治疗后wagner 分级0级(35.71%)和Ⅰ级(38.10%)占比显著高对于对照组(20.00%、25.00%),而Ⅱ级(23.81%)和Ⅲ级(2.38%)占比则显著低于对照组(37.50%、17.50%),差异具有统计学意义(p＜0.05).结论:糖尿病足患者西医治疗基础上,增加四妙勇安汤内服,可进一步促进足部病变愈合康复,提升疗效,应用效果良好.

Objective To investigate one -step overall treatment to improve the condition of diabetic foot ulcers based on transluminal technology.Methods The patients with diabetic foot ulcers were treated with percutaneous transluminal angioplasty(PTA)to open blood flow,intensively control patients'blood glucose,application of sensitive antibiotics,erode debridement and dressing change according to wound bed preparation(WBP)and moist wound heal, vacuum aspiration was applied in large wound.Results Eighty -two patients(eighty -five lower limbs)underwent PTA,the successful rate was 100.0%.Of 116 ulcers,106 cases were effective (91.4%),10 cases were invalid (8.6%).Their ankle -brachial index (ABI)increased from preoperatively (0.41 ±0.12)to postoperatively (0.75 ± 0.09).Transcutaneous oxygen pressure(TcPaO2 )increased from preoperatively (14.6 ±4.8)mmHg to postopera-tively (51.6 ±8.9)mmHg.Conclusion One -step treatment regarding multi disciplinary team on endocrine section can improve the treatment of diabetic foot and lower the amputation rate.

Objective To Explore the relationship of the patients with type 2 diabetes between urine trace albumin amd homocysteine levels and the carotid intima-media thickness. Methods 162 cases of patients with type 2 diabetes, according to color doppler ultrasonic diagnostic instrument measurement of carotid intima-media thickness, analyse the urine trace albumin, homocysteine and the relationship between the carotid intima-media thickness. Results The pa?tients are divided into two groups according to carotid intima thickness, the normal group has 83 cases, thicking group has 82 cases. The carotid intimal thickening is significant (P<0.05). Conclusion Patients with type 2 diabetes urine trace al?bumin, homocysteine levels and neck IMT were positively correlated, is thickening of risk factors for carotid intima-me?dia thickness, suggests the urine trace albumin, homocysteine can be as an indicator to predict the thicness of the carotid intima-media thickness.

Objective To investigate the efficacy of a comprehensive treatment method for the treatment of diabetic foot ulcers.Methods 63 patients in the intensive treatment with insulin or insulin pump strict glycemic control,nutrition nerve microcirculation,antibiotic was taken in accordance with susceptibility testing, debridement and dressing according to the theory of wound bed preparation and wet therapy, if necessary, endovascular treatment blood was opened.Results63 patients with 98 ulcers,61 were healed (62.2%);improved 22 cases (22.5%),84.7% of the total valid,invalid 15 cases (15.3%),where amputation (toe) 4 cases (4.0%).Conclusion The etiology of diabetic foot complex,such as blood vessels,nerve disease and infection factors involved,comprehensive treatment can significantly improve the cure rate and limb salvage rate,shorten the course.

<正>高渗性昏迷是内科急症之一,此病的特点是严重高血糖、脱水及血浆渗透压增高,而无明显的酮症酸中毒,患者的神志可以正常,但多有嗜睡、昏睡或昏迷,常合并多脏器功能衰竭,病情危重,病死率高,可达40%[1]。现将我们抢救高渗性昏迷患者36例体

Diabetes is often accompanied by gastrointestinal symptoms, high incidence of gastrointestinal disorders and liver, gallbladder, pancreas disease, gastrointestinal disease called diabetes [1]. Variety of clinical treatment effects but no way. A triazine compound we used m the treatment achieved good results.

<正>随着社会的发展,2型糖尿病的发病率越来越高。其慢性并发症是导致糖尿病患者致残和致死的主要原因。UKPDS等大型临床研究已证实:严格控制血糖能延缓或减少糖尿病血管、神经等并发症的发生。为患者选用一种安全、有效、方

糖尿病并发周围神经病变是糖尿病常见的慢性并发症之一,是糖尿病患者致残、生活质量下降的最常见原因.我们在严格控制血糖的基础上应用单唾液酸四己糖神经节苷脂(GM1)治疗取得了较好的效果.现报告如下.

目的:探讨H3受体拮抗剂格拉斯琼对糖尿病所致功能性幽门梗阻的治疗效果。方法:32例糖尿病所致功能性幽门梗阻病例随机分为两组,治疗组应用格拉斯琼3mg,对照组应用胃复安30mg分别加入生理盐水250ml静脉滴注,疗程为5d。疗程结束,治疗组15例治愈,1例好转,有效率为100%。对照组16例患者疗程结束,4例好转,12例无效,有效率为25%。结果:H3受体拮抗剂格拉斯琼能选择性阻断中枢及迷走神经传入纤维5-HT3受体产生强大止吐作用,能切断幽门水肿-梗阻-呕吐的恶性循环链。结论:格拉斯琼是治疗糖尿病所致功能性幽门梗阻的有效药物。

胰岛素强化治疗能明显降低糖尿病患者的病死率和并发症.国内外现有研究多采用持续性皮下胰岛素输注方案或4次皮下注射的方法强化治疗,但因以下局限性而使患者的依从性下降,临床应用受限:①费用昂贵,难以大面积推广;②注射次数多,应用繁琐;③低血糖发生率高.其中低血糖的发生目前已成为患者严格控制血糖的重要障碍.赖脯胰岛素75/25早晚餐前皮下注射应用简便、价格适中,笔者观察了其在胰岛素强化治疗中的有效性和安全性,现将结果报道如下.

目的探讨应用彩色多普勒超声检测2型糖尿病患者颈动脉病变情况。方法对62例糖尿病患者应用彩超进行双侧颈动脉检测。结果62例患者中双侧颈动脉均显示正常的30例,仅占48.39%。单支血管病变29处,2支以上为114处。结论早期糖尿病患者即有明显颈动脉病变,彩超可直观反映病变的分期、轻重程度,有重要的实用价值。

肾上腺是重要的内分泌器宫,早期的功能异常和形态变化多无明显临床症状.CT检查是肾上腺形态学变化的重要诊断手段.为探讨肾上腺CT变化与相关疾病的关系,给临床鉴别诊断提供参考,本文对行肾上腺CT检查的239例病历进行回顾性分析.

目的调查平度市农村地区2型糖尿病患病率。方法以平度市农村地区居住≥5年,年龄20～74岁人群为调查对象,分层随机整群抽样4298人。结果抽样4298人中新诊断糖尿病患者154例,已确诊糖尿病人104例。结论农村地区糖尿病患者确诊率低,知晓率低,应加强普查。

阿贝他(苯扎贝特)属苯氧乙酸类衍生物,是贝特类调脂药物.本研究中,我们观察了阿贝他对血糖的影响.

Objective The study was to determine the alterations of Sprague-Dawley (SD) rats in systolic blood pressure (SBP) and glucose/insulin induced by high sucrose intake and see if the alterations can be prevented by Magnesium Oxide treatment.Method Thirty six SD rats were randomly divided into four groups:Control group (C,n=9),in this group,rats ate standard chow,drank tap water at will;Control-Magne-sium treated group (CT,n=9),rats ate standardchow and 1% Magnesium (1.67% Magnesium Oxide w/w/%),drank tap water and libitum;Sucrose group (S,n=9),in this group,rats ate standard chow,drank 10% sucrose-tap water solution (w/v/%);Sucrose-Magnesium Oxide treated group (ST,n=9),rats ate standard chow and 1.67% Magnesium Oxide,drank 10% sucrose-tap water solution.Weekly measurements of systolic blood pressure (SBP) and body weight (BW) were conducted after rats were accommodated to new invironment and the procedure of blood pressure measurement.The experiment lasted for 6.5 weeks.Blood samples were taken after 5h fasting on the last day.Then blood concentrations of glucose (GLU),insulin (INS) and C-peptide (CP) were measured.Result Compared with group C,group S showed an increase in SBP,in INS,in CP (P0.01);Magnesium Oxide treatment in ST group effectively prevented the increments in SBP,in INS,in CP (P0.01,P0.05).Conclusion High sucrose intake induce hypertension and hyperinsulinemia in SD rats and these disorders can be prevented by Magnesium Oxide treatment.These data indicate beneficial effects of Magnesium treatment on carbohydrate metabolism in hyperinsulinemic insulin-resistant status.

影像学检查是肾上腺疾病诊断的主要方法之一.

笔者运用中西医结合方法,治疗泌尿系结石65例,效果显著,现报道如下. 1临床资料 1.1一般资料:65例均为门诊病例,其中男53例,女12例,年龄16～65岁,平均49岁;全部病例均有腰或下腹部疼痛,或突然绞痛,肉眼血尿或尿检红细胞阳性;B超或腹部平片证实结石存在;其中肾结石47例,输尿管结石16例,膀胱结石2例.