OBJECTIVE To study the patent literature of traditional Chinese medicine in the treatment of liver ascites,and to provide reference for new drug research and development in this field.METHODS According to the Chinese patent database,SFDA website as the retrieval source,liver ascites,cirrhosis and traditional Chinese medicine as the key words,the patent application published in 1991-2017 was searched,and then through artificial noise reduction.METHODS The final liver ascites literature was identified and analyzed by IPC classification,applicant type,key applicant,legal status and so on.RESULTS A total of 242 Chinese medicine patent documents were collected,including 12％ of the total number of patents,62％ of the total number of patents,and 62％ of the total number of patents.The main body of the patent application was natural.In terms of the growth rate of patent applications,the trend of patent applications in this area had increased year by year,but so far there had been no listing of proprietary Chinese medicines specifically targeted at such diseases.CONCLUSION There are few effective patent cases in the treatment of liver ascites,and the results are low in industrialization.At present,there are no drugs specifically listed in the listed Chinese medicine.Therefore,it has developed a market with independent intellectual property rights for the treatment of liver ascites.prospect.
目的：探讨持续气道正压通气（ CPAP）治疗对重症高血压脑出血患者术后康复的影响。方法将208例神经外科住院部病例随机分为对照组和治疗组各104例。对照组采用常规治疗，治疗组在常规治疗的基础上进行CPAP治疗，比较2组呼吸参数的变化并评定术后神经功能缺损程度。结果治疗组治疗后较治疗前呼吸暂停时间明显减少，血氧饱和度增高，差异均有统计学意义（P＜0．05）。对照组治疗前后呼吸暂停时间及血氧饱和度差异均无统计学意义（P＞0．05）。治疗组的总有效率为90．38％高于对照组的69．23％，差异有统计学意义（P＜0．05）。结论有效的CPAP，可减少呼吸暂停次数，提高血氧饱和度，从而改善神经功能恢复情况，值得在临床上应用推广。
目的：探讨持续气道正压通气（ CPAP）配合健康教育及早期康复训练对重症脑出血患者术后功能恢复的影响。方法将380例重症脑出血手术治疗患者随机分为试验组130例、对照组A130例和对照组B120例。试验组给予CPAP配合健康教育及早期康复训练治疗；对照组A给予CPAP及早期康复训练；对照组B给予健康教育及早期康复训练。治疗3月后评价所有患者功能恢复情况和治疗效果。结果试验组患者治疗和康复总有效率均高于对照组A、B，差异均有统计学意义（P＜0．05）；对照组A的治疗和康复效果略低于B组，但差异无统计学意义（P＞0．05）。结论 CPAP配合健康教育及早期康复训练对重症脑出血术后功能恢复的效果较单纯CPAP及早期康复训练或健康教育及早期康复训练显著。
