BACKGRAUND : Violation of gait and body balance in patients with diabetic polyneuropathy actualizes the development of new effective measures of motor rehabilitation. In this regard, an observation was carried out in which biofeedback training was used for the reference reaction in the conditions of variable feedback parameters. AIMS : To investigate the effect of a stepwise change in the depth of feedback (sensitivity) in a motor-cognitive task with visual feedback on the reference response to the result of its execution. METHODS : Single-sample observational observation with controlled conditions. 27 patients with diabetic polyneuropathy. All patients were treated according to modern standards. The observation was performed in one series at the beginning of the course of inpatient treatment. Estimation of body balance on a power platform — stabiloplatform) — stabilometry. The procedure included 5 stages of management, in which the patient followed the instructions (training) in which there was a stepwise increase in the depth of feedback («sensitivity») at each stage from 10 to 50% of the conditional «normal», with a step of 10%. A quantitative assessment of the external result (execution of instructions) and parameters of regulation of the vertical posture was carried out. RESULTS : All patients included in the follow-up showed that the implementation of instructions with increasing depth of feedback decreased sharply when the conditionally «normal» value was exceeded by 30–35%. At the same time, the initial parameters of vertical posture control in the sample patients did not affect the dynamics of results when performing the task with visual feedback. Factor analysis indicates the presence of the only significant factor associated with the effectiveness of performing a motor-cognitive task here — changes in the depth of feedback. The accepted significance level α = 0.05. CONCLUSIONS : The depth of feedback in motor-cognitive tasks with visual feedback is a key characteristic that affects performance. The ability to increase the depth of feedback in the range of about 35; from conditionally «normal», can be useful for ensuring differentiation of loads during motor rehabilitation of patients in order to increase the effectiveness of training. In addition, in theoretical terms, the proposed model of the motor-cognitive problem can be relevant in the study of «dual» problems, where the relationship of motor and cognitive components is studied.

BACKGRAUND: Violation of gait and body balance in patients with diabetic polyneuropathy actualizes the development of new effective measures of motor rehabilitation. In this regard, an observation was carried out in which biofeedback training was used for the reference reaction in the conditions of variable feedback parameters.AIMS: To investigate the effect of a stepwise change in the depth of feedback (sensitivity) in a motor-cognitive task with visual feedback on the reference response to the result of its execution.METHODS: Single-sample observational observation with controlled conditions. 27 patients with diabetic polyneuropathy. All patients were treated according to modern standards. The observation was performed in one series at the beginning of the course of inpatient treatment. Estimation of body balance on a power platform — stabiloplatform) — stabilometry. The procedure included 5 stages of management, in which the patient followed the instructions (training) in which there was a stepwise increase in the depth of feedback («sensitivity») at each stage from 10 to 50% of the conditional «normal», with a step of 10%. A quantitative assessment of the external result (execution of instructions) and parameters of regulation of the vertical posture was carried out.RESULTS: All patients included in the follow-up showed that the implementation of instructions with increasing depth of feedback decreased sharply when the conditionally «normal» value was exceeded by 30–35%. At the same time, the initial parameters of vertical posture control in the sample patients did not affect the dynamics of results when performing the task with visual feedback. Factor analysis indicates the presence of the only significant factor associated with the effectiveness of performing a motor-cognitive task here — changes in the depth of feedback. The accepted significance level α = 0.05.CONCLUSIONS: The depth of feedback in motor-cognitive tasks with visual feedback is a key characteristic that affects performance. The ability to increase the depth of feedback in the range of about 35; from conditionally «normal», can be useful for ensuring differentiation of loads during motor rehabilitation of patients in order to increase the effectiveness of training. In addition, in theoretical terms, the proposed model of the motor-cognitive problem can be relevant in the study of «dual» problems, where the relationship of motor and cognitive components is studied.

В данной статье рассматриваются различные виды проектной деятельности, которые возможно организовать на начальном этапе обучения русскому языку как иностранному. В данном случае пассивное усвоение знаний заменяется активной познавательной деятельностью, которая развивает самостоятельные навыки у студентов, формирует креативное мышление. Данные виды проектной деятельности должны проходить под гибким контролем со стороны педагога, так как студенты владеют русским языком еще пока на невысоком уровне, поэтому им требуется непосредственная помощь педагога. В статье представлен опыт организации проектной деятельности как традиционным способом обучения, так и дистанционным.

О ФИЗИОЛОГИЧЕСКОЙ ОСНОВЕ НЕКОТОРЫХ СТИЛЕЙ ПОВЕДЕНИЯ (КРАТКОЕ СООБЩЕНИЕ

Aim. The study deals with the assessment of the effect of biological feedback with various parameters on controlling vertical position in human. This is necessary to justify physiologically the choice of an adequate control regime. Materials and methods. 25 apparently healthy volunteers aged 18–35 participated in the study. These volunteers are not professional athletes. The main method is the assessment of biocontrol parameters using the ground reaction data obtained with a force plate. Results. We revealed that an increase in feedback depth during the biocontrol assessed using the ground reaction data obtained with the force plate with a visual channel decreases the efficiency of vertical position targeted control. Moreover, we defined the extreme range of an increase in the coefficient of transformation of the physiological signal (sensitivity). This was done to obtain the coordinates of the common center of pressure on the ground, which preserves the ability of targeted control in untrained volunteers and equals approximately 50–70 % of standard values. Conclusion. Changes in the depth of biological feedback is a key factor, which influences the efficiency of procedures with biological feedback.

The extensive application of various types of biological feedback mechanisms for the purpose of medical rehabilitation, e.g. as exemplified by «immersion» of the patient in the synthetic («virtual», «enhanced») environment, poses an important problem concerning the terminology, definitions, identification of the differences, and the selection of such artificial realities. In the current Nomenclature of medical services introduced into the clinical practice by the Order of the Ministry of Health of the Russian Federation (No 1664n dated 27.12.2011), the following codes can be attributed to the items concerning the possible use of virtual environments: A19.03.001.014 «Training with biological feedback from the support reaction in patients presenting with spinal injury» or A19.03.001.017 «Training with biofeedback via the kinesiology image of the manner of motion in the patients suffering from spinal injury», etc. At present, the use of the virtual environments and objects for the purpose of relaxation which are yet not coded as the medical services is extensively practiced at the treatment-and-prophylactic establishments of the spa and health resort type. This brief review is perhaps the first or one of the first attempts to explicitly define and represent the multidisciplinary approach to the problem being analyzed in the context of medical rehabilitation with the consistent information synthesis. The aim of the present work was to provide rehabilitation medicine professionals and other specialists with the information pertaining to the interpretation of the materials having a bearing on the main line of these studies.

In an experimental study 40 girl students of 7th grade were selected using random cluster sampling from one middle school in Tehran and divided into test and control groups by random assignment. Initially they were assessed by working memory capacity test (Daneman & Carpenter, 1980). Then, the test group through 12 educational sessions (one hour sessions, 3 sessions per week) was taught relaxation techniques, and it is noteworthy that no education was given to a control group. Upon completion of educational sessions, both test and control groups were assessed again with the working memory capacity test. In the case of the academic achievement, the Grade Point Average (GPA) of the first semester for pre-test and the GPA of the second semester for post-test were used. Multivariate analysis of covariance showed that relaxation training increase working memory capacity and its components, storage and processing, and academic achievement. Therefore, relaxation training is a useful technique for student progress.

Statistically significant differences in the stabilometric parameter, an index associated with physical estimation of work, were detected in 13 healthy young volunteers assuming a vertical posture with the eyes closed before and after performing a motor task (a 3-min session of support reaction control with biofeedback). An increase in posture stability after the procedure was accompanied by changes in the power distribution of EEG signals (in the 8–13 Hz range) recorded on the surface of the scalp. The observed effect consisting in an increased postural stability can be interpreted as a “rapid response” to performing a motor task; therefore, it offers the possibility of using a relatively simple approach for the monitoring of switching between functional states associated with various motor procedures and tests.

The European Atherosclerosis Society Familial Hypercholesterolaemia Studies Collaboration (FHSC) global registry provides a platform for the global surveillance of familial hypercholesterolaemia through harmonisation and pooling of multinational data. In this study, we aimed to characterise the adult population with heterozygous familial hypercholesterolaemia and described how it is detected and managed globally.Using FHSC global registry data, we did a cross-sectional assessment of adults (aged 18 years or older) with a clinical or genetic diagnosis of probable or definite heterozygous familial hypercholesterolaemia at the time they were entered into the registries. Data were assessed overall and by WHO regions, sex, and index versus non-index cases.Of the 61 612 individuals in the registry, 42 167 adults (21 999 [53·6%] women) from 56 countries were included in the study. Of these, 31 798 (75·4%) were diagnosed with the Dutch Lipid Clinic Network criteria, and 35 490 (84·2%) were from the WHO region of Europe. Median age of participants at entry in the registry was 46·2 years (IQR 34·3–58·0); median age at diagnosis of familial hypercholesterolaemia was 44·4 years (32·5–56·5), with 40·2% of participants younger than 40 years when diagnosed. Prevalence of cardiovascular risk factors increased progressively with age and varied by WHO region. Prevalence of coronary disease was 17·4% (2·1% for stroke and 5·2% for peripheral artery disease), increasing with concentrations of untreated LDL cholesterol, and was about two times lower in women than in men. Among patients receiving lipid-lowering medications, 16 803 (81·1%) were receiving statins and 3691 (21·2%) were on combination therapy, with greater use of more potent lipid-lowering medication in men than in women. Median LDL cholesterol was 5·43 mmol/L (IQR 4·32–6·72) among patients not taking lipid-lowering medications and 4·23 mmol/L (3·20–5·66) among those taking them. Among patients taking lipid-lowering medications, 2·7% had LDL cholesterol lower than 1·8 mmol/L; the use of combination therapy, particularly with three drugs and with proprotein convertase subtilisin–kexin type 9 inhibitors, was associated with a higher proportion and greater odds of having LDL cholesterol lower than 1·8 mmol/L. Compared with index cases, patients who were non-index cases were younger, with lower LDL cholesterol and lower prevalence of cardiovascular risk factors and cardiovascular diseases (all p<0·001).Familial hypercholesterolaemia is diagnosed late. Guideline-recommended LDL cholesterol concentrations are infrequently achieved with single-drug therapy. Cardiovascular risk factors and presence of coronary disease were lower among non-index cases, who were diagnosed earlier. Earlier detection and greater use of combination therapies are required to reduce the global burden of familial hypercholesterolaemia.Pfizer, Amgen, Merck Sharp & Dohme, Sanofi–Aventis, Daiichi Sankyo, and Regeneron.

We aim to describe management of a patient receiving renal transplantation for chronic renal failure due to Alport syndrome with low dose of intrathecal bupivacaine and continuous epidural infusion of local anesthetic.A 38-years-old man with chronic renal failure secondary to Alport syndrome underwent kidney transplantation. Because of a high risk of respiratory and cardiovascular complications related to the patient's baseline lung disease and abnormalities in heart conduction, we selected combined spinal-epidural anesthesia. The block was ultrasound-guided and performed at the T12-L1 interspace with 4.5 mg of 0.5% intrathecal hyperbaric bupivacaine followed by a continuous epidural infusion of 0.5% levobupivacaine mixed with 25 μg of Fentanyl at the initial rate of 8 mL/h. Sensory block to T5-T6 was obtained within 10 minutes. The patient then received mild sedation with Propofol and Remifentanil. Methylprednisolone and diuretics were administered before vascular unclamping according to our internal protocol. Surgery lasted 3 hours with no clinical or procedural complication.Although renal transplantation is usually performed under general anesthesia, in a particularly complex patient with chronic renal failure, chronic obstructive pulmonary disease and a worsened respiratory mechanics, we applied a combined approach with a low dose of intrathecal bupivacaine and continuous epidural infusion of local anesthetic. The technique did not affect hemodynamics while having a positive impact on recovery of function of the transplanted organ with rapid improvement of urine output, serum creatinine, and blood urea nitrogen levels.

Возрождение ценностного отношения к человеку становится частью современного процесса демократизации государства и общества. Между тем, российская политическая реальность вновь обращает нас к повседневным проблемам реализации прав человека. Данная статья представляет собой попытку научного осмысления существующих проблем, а также поиска путей их разрешения.

Рассматривается проблематика зависимости студентов от всемирной сети «Интернет». Следствием такой зависимости зачастую является подмена собственных умозаключений студента при написании рефератов и других самостоятельных работ информацией, взятой из интернет-источников. В статье предложены педагогические рекомендации, способствующие выработке у студентов самостоятельного, критического, созидательного мышления.The work provided deals with the problem of students’ ever growing dependence from Internet and its resources. As the result its common knowledge, that very often students use to take Internet-information, found in various sources instead of appealing to their own thoughts and conclusions. Certain pedagogical recommendations, aimed at developing in students independent, critical and creative thinking, age suggested in the article.