The Journal “PEDIATRIA. Journal named after G.N. Speransky” and its Memorable Milestones.

(Педиатрическая фармакология. — 2011; 8 (6): 142–145).

Are examined questions of the depletion of the ration of contemporary person by the large number of biologically active materials, decrease of the solid characteristics of the food as a result of a change of the technology of cookery in the process of the development of civilization. Reduction in the resistance of organism and increase in its morbidity is the result of this change in the nature of nourishment. In recent years the food variety the functional products, which possess the specific nourishing properties, ever more confidently invade, renders the goal-directed action on the functional activity of individual organs, systems and organism as a whole, they stimulate their fitness for work with the concrete preventive and medical and sanitary purpose. Three groups of the bioactive substances are the basic components of functional products: adaptogeny, prebiotiki and their combination. Is carried out the analysis of the consumption of the products of functional nourishment in the world, the ratio of the population of the different countries to these goods and the basic reasons for their application. Among the health-improvement products, realized in the Ukraine, dairy products occupy special position. The expansion of assortment is observed also in the baked industry. The development of scientific approaches to the creation of new functional food products, which according to the type of substitute therapy would render the expressed biological effect on the human organism is important. Significant role in the solution of the problem of functional nourishment play NPA “Odessa biotechnology” and SLR “Of biokhimtekh”, in laboratories of which several ten dietetic additives to the food with the functional properties are developed.

Treatment of the gastroenterological diseases associated with the helicobacterial infection is a complex issue. This is due to the new strains of microorganisms resistant to the medications applied. Based on the data acquired during the examination of 30 children, they showed the high efficacy of the scheme for the triple eradication therapy against helicobacteriosis, which included nifuroxazide suspension (enterofuril) along with omeprazole and clarithromycin. The authors also substantiated the expediency to prolong the treatment up to 10–14 days to improve the eradication efficacy. Key words: children, helicobacter pylori, nifuroxazide, treatment.

Treatment of the gastroenterological diseases associated with the helicobacterial infection is a complex issue. This is due to the new strains of microorganisms resistant to the medications applied. Based on the data acquired during the examination of 30 children, they showed the high efficacy of the scheme for the triple eradication therapy against helicobacteriosis, which included nifuroxazide suspension (enterofuril) along with omeprazole and clarithromycin. The authors also substantiated the expediency to prolong the treatment up to 10–14 days to improve the eradication efficacy.Key words: children, helicobacter pylori, nifuroxazide, treatment.

The article is about fenspirid (Erespal) medication to combat acute respiratory infections (ARI) of infants. 94 children aged 1–3 suffering from ARI were observed: of them 64 took fenspirid, 30 children didn't take it (the control group). The research has revealed that fenspirid reduces ARI manifestation even if ARI proceeds along with ordinary or obstructive bronchitis — accordingly, fenspirid can be recommended for a wider usage to cure ARI of infants up to 3 years of age.Key words: fenspirid, infants up to 3 years of age, acute respiratory infection.

Among the sickly children, pharyngitis and tonsillopharyngitis are quite often accompanied by pain and scratch in a throat, which is anguished for a child themselves and causes parents to worry. In the therapy for the indicated pathology, a certain place is held by a local antibiotic fusafungine. In the article, the author studies the effects of fusafungine on tonsillitis/tonsillopharyngitis and pharyngitis, running with pain in a throat, among the sickly children aged between 3 and 15. The research was carried on in 42 centers of different Russian regions and became a part of the multicentered research according to «Chibis» program. 2,609 children were examined, 1,907 of who Received fusafungine and 702 children did not. Among 78,1% of the children, the authors noted the phenomena of pharyngitis, rhinopharyngitis and acute tonsillopharyngitis. As the research showed the symptoms of rhinopharyngitis and tonsillopharync gitis were reliably arrested much faster, when applying fusafungine, thus, the clinical effects mostly emerged after 4th–5th day of the therapy. The acquired data allowed one to recommend the inclusion of fusafungine into the therapy for acute rhinopharyngitis, pharyngitis and tonsillopharyngitis among the sickly children.Key words: rhinopharyngitis, pharyngitis, tonsillopharyngitis, fusafungine, children, treatment.

(Voprosy sovremennoi pediatrii = Current pediatrics. 2006;5(5):102-103)