St John's Wort (Hypericum perforatum) is the main herbal species used to treat depression. The products available on the pharmaceutical and dietary supplement markets are obtained by a variety of preparation processes and their pharmacological effects may differ significantly. The purpose of this study therefore was to investigate the effect of different St John's Wort commercial preparations available on the French market. Only one preparation gave significant results in the forced swimming test. Copyright © 2006 John Wiley & Sons, Ltd.

We report on the isolation of a murine homeobox-containing gene, Six6 (Optx2), that shows extended identity in its coding region with Six3, the only member of the mammalian Six gene family known to be expressed in the optic primordium. Phylogenetic analysis demonstrates that Six6 and Six3 belong to a separate group of homeobox-genes that are closely related to the recently identified Drosophila optix. Earliest Six6 expression was detected in the floor of the diencephalic portion of the primitive forebrain, a region predicted to give rise to the neurohypophysis and to the hypothalamus. Later on, Six6 mRNA was found in the primordial tissues giving rise to the mature pituitary: the Rathke's pouch and the infundibular recess. In the optic primordium, Six6 demarcates the presumptive ventral optic stalk and the ventral portion of the future neural retina. In the developing eye, Six6 expression was detected in the neural retina, the optic chiasma and optic stalk, but not in the lens. When compared to Six6, Six3 expression pattern was highly similar, but with a generally broader transcripts distribution in the brain and in the visual system. We finally show that Six6 does not require Pax6 for its expression in the optic primordium, suggesting that Six6 acts on a parallel and/or independent pathway with Pax6 in the genetic cascade governing early development of the eye.

Equine Veterinary EducationVolume 10, Issue 1 p. 17-20 Congenital bilateral distal defect of the ureters in a foal D. Jean, D. Jean Département de Médecine, Faculté de Médecine Vétérinaire, Université de Montréal, St-Hyacinthe, C.P. 5000, St-Hyacinthe, Québec, Canada, J2S 7C6 Clinique Equine, Ecole Nationale Vétérinaire d'Alfort, 7 Avenue du Général de Gaulle, 94704 Maisons-Alfort Cedex, FranceSearch for more papers by this authorM. Marcoux, M. Marcoux Département de Médecine, Faculté de Médecine Vétérinaire, Université de Montréal, St-Hyacinthe, C.P. 5000, St-Hyacinthe, Québec, Canada, J2S 7C6Search for more papers by this authorC.-F. Louf, C.-F. Louf Département de Médecine, Faculté de Médecine Vétérinaire, Université de Montréal, St-Hyacinthe, C.P. 5000, St-Hyacinthe, Québec, Canada, J2S 7C6 Clinique Vétérinaire d'Epinal, 48 rue André Vito, 98000 Epinal, FranceSearch for more papers by this author D. Jean, D. Jean Département de Médecine, Faculté de Médecine Vétérinaire, Université de Montréal, St-Hyacinthe, C.P. 5000, St-Hyacinthe, Québec, Canada, J2S 7C6 Clinique Equine, Ecole Nationale Vétérinaire d'Alfort, 7 Avenue du Général de Gaulle, 94704 Maisons-Alfort Cedex, FranceSearch for more papers by this authorM. Marcoux, M. Marcoux Département de Médecine, Faculté de Médecine Vétérinaire, Université de Montréal, St-Hyacinthe, C.P. 5000, St-Hyacinthe, Québec, Canada, J2S 7C6Search for more papers by this authorC.-F. Louf, C.-F. Louf Département de Médecine, Faculté de Médecine Vétérinaire, Université de Montréal, St-Hyacinthe, C.P. 5000, St-Hyacinthe, Québec, Canada, J2S 7C6 Clinique Vétérinaire d'Epinal, 48 rue André Vito, 98000 Epinal, FranceSearch for more papers by this author First published: 26 April 2010 https://doi.org/10.1111/j.2042-3292.1998.tb00841.xCitations: 21 AboutPDF ToolsExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Citing Literature Volume10, Issue1February 1998Pages 17-20 RelatedInformation

18C has been produced as a projectile fragment in the interaction of a 60 MeV/u 22Ne beam with a thick beryllium + carbon target. Using the LISE spectrometer of GANIL tuned according to the PFIS method allowed an unprecedented measurement of its β-delayed γ spectroscopy, along with redetermination of half-life and β-neutron branching ratio. A partial decay scheme is proposed. A comparison with theoretical predictions provides a qualitative understanding of the decay of 18C.

The beta-gamma spectroscopic study of22O is presented. This nucleus, produced as a projectile-like fragment from the interaction of a 60 MeV/n40Ar beam with a Be target, has been separated by the LISE spectrometer. Several gamma rays from22O decay have been observed, from which a half-life of (2.25±0.15)s has been determined. Accurate excitation energies have been deduced for several states in22F. A partial beta decay scheme of22O has been established. Experimental results have been compared with shell model calculations.

The beta-gamma spectroscopic study of22O is presented. This nucleus, produced as a projectile-like fragment from the interaction of a 60 MeV/n40Ar beam with a Be target, has been separated by the LISE spectrometer. Several gamma rays from22O decay have been observed, from which a half-life of (2.25±0.15)s has been determined. Accurate excitation energies have been deduced for several states in22F. A partial beta decay scheme of22O has been established. Experimental results have been compared with shell model calculations.

Abstract The three nuclei 17B, 14Be, 19C have been produced and separated by the LISE spectrometer at GANIL. Half-lives and beta-delayed neutron multiplicities have been determined for these nuclei. The study of 17B has allowed us to observe for the first time the beta-delayed four-neutron decay mode with a branching ratio p4n=(4±3)×10−3.

A new method for the isotopic separation of projectile fragments is exposed. The application to the LISE spectrometer at GANIL provided radioactivity data on light neutron‐rich nuclei (mass range 14–40). The observation on 17B of the beta‐delayed four neutron decay mode is reported for the first time.

The thirteen above-listed isotopes have been produced at GANIL by fragmentation of a40Ar beam at 60 MeV/nucleon. The LISE spectrometer allowed us to isotopiaally separate these nuclei. Beta delayed gamma spectroscopy was carried out for the first time for eleven isotopes and additional information was obtained for another two.

The isotopic separation of intermediate-energy (30 to 100 MeV per nucleon) heavy-ion projectile fragments is theoretically and experimentally investigated. Physical separation of nuclides is achieved through magnetic analysis (AZ sensitivity) and differential stopping-power effects (Z−2 sensitivity). Depending on the specific case, a complete mass and charge separation may be achieved or a few nuclides may be selected simultaneously. The projectile fragments isotopic separation method described allows us to obtain an experimental mass separation AΔA ≈ 100. Simple formulae are given to determine the optimum factors for the best separation and transmission of the device. First applications to the spectroscopy of exotic nuclei lead to the new observation of the beta decay of 37P at GANIL and 15B at CERN.

The thirteen above-listed isotopes have been produced at GANIL by fragmentation of a40Ar beam at 60 MeV/nucleon. The LISE spectrometer allowed us to isotopiaally separate these nuclei. Beta delayed gamma spectroscopy was carried out for the first time for eleven isotopes and additional information was obtained for another two.

The target fragmentation induced by particule beams is since long recognized as a powerful tool to produce exotic nuclei. Nearly all nuclei with neutron and proton numbers less than that of the target are produced. The drawback of such a wide production is that it implies the use of efficient Z and A selective devices in order to be able to carry detailed spectroscopic measurements. Although very productive, the well-known ISOL facilities do not cover the full range of elements and even in a favorable case like cesium they may fail to separate short-lived isotopes like 113Cs which decays by proton emission. An interesting alternative to ISOL techniques is now available with the fragmentation of heavy ion beams which is essentially equivalent to target fragmentation except for the inverse kinematic. At energies higher than 40Mev/n projectile fragments are forward focused with velocities close to that of the beam.

La chromatographie en phase gazeuse, couplée à la spectrométrie de masse utilisant la détection par sélection d'ions, a permis de mettre en évidence l'acide tuberculostéarique (ou 10-méthyloctadécanoïque), constituant caractéristique des mycobactéries. L'ionisation par impact électronique est une méthode suffisante pour la détection de cet acide dans les cultures de M. tuberculosis. Dans les expectorations ou le L.C.R., pour augmenter la sensibilité de la détection, nous avons essayé l'ionisation chimique. Par cette technique, nous avons pu rétrospectivement mettre en évidence cet acide dans le premier prélèvement de L.C.R. d'un enfant suspecté de méningite tuberculeuse où les examens directs de bactériologie étaient restés négatifs.