Results : 2322 patients[52%males, age=52yrs, BMI 26 (15-64) Kg/m2, 61%H; 11%D and 28%DH] were included.The prevalence of presumed AF were H 2.5%, D 6.5% and DH 9% (P < 0.0001).AS was presumed in H 11%, D 23% and DH 39% (P < 0.0001).During a median follow-up of 12yrs, 183 (7.8%) patients died[35 CVD; 6 LRD (4 hepatocellular-carcinoma and 2 cholangio-carcinoma)].Both OS and survival without-CVD were significantly higher in H than in D or DH (%Kaplan-Meier, 95% CI): OS 96 (95-97) vs 93 (91-96, Logrank P < 0.001 vs H) vs 88 (85-92, P < 0.0001 vs H), respectively.Survival without CVD: 99 (98-99) vs 98 (96-99, P = 0.02 vs H) vs 97 (96-99, P < 0.001 vs H), with no LRD in H-group.OS and survival without-LDR in AF vs non-AF presumed by FT were: D-group 81 (62-99) vs 94 (91-97, P = 0.04) and 94 (82-99) vs 100 (99-100, P < 0.01); DH-group 72 (55-88) vs 89 (86-93, P = 0.04) and 90 (81-99) vs 100 (99-100, P < 0.0001), respectively.H-group with AS presumed by Steatotest had lower survival without-CVD, compared to non-AS: 97 (94-99) vs 99 (98-99, P = 0.004).In multivariate analysis (Cox model): Fibrotest remained significant for the prediction of OS in D-group[risk ratio (RR)=136.9(95% CI 11.6-1610; P < 0.0001)] and in DH-group [RR=7.1 (95% CI 2.1-24; P < 0.0001)]. Conclusion:Patients with type-2 diabetes especially those with associated hyperlipidemia presented higher rates of advanced fibrosis and steatosis and also higher overall and liver-related mortalities than those with isolated hyperlipidemia.In diabetics, regardless associated hyperlipemia, FibroTest had a significant 10years prognostic value for the overall and without liver-related death survivals.SteatoTest was predictive of cardiovascular-related death in hyperlipidemia patients.
A case is presented of a patient with a jejunoileal (JI) bypass in which the diagnosis of cecal carcinoma was made by anterograde colonoscopy.
AASLDA1427parameters were eva luated through catheteri zatio n (liver blood flow LBF, transhepatic pressure gradient WHVP and HVPG).Additional liver function tests (MEGX-test, ICG-test) were perfo rmed .Histology includ ed a standardized coding (4 levels) regardi ng degree of fat, inflammation, necrosis, ce ll volume, cholestasis and fibrosis.Results: The PDcalculated portal flow volume correlated we ll with the LBF (r= 0.82, p=0.023).With increa sed liver cell size (smaller than ce ll hydrops) the PDcalcul ated portal flow volume increased (r = 0.6, p = 0.039) and the RI of hep atic artery decre ased (r= -0.57, p=0.032).Enlarged cell size was assoc iated with an incre ment of ICGclearan ce (normal vs. enlarge d: 3.43:':0.97vs. 4.72 :': 1.09 mll min/kgKG, p = O.OI, Wilcoxon) and redu ced cholestasis (normal vs. enlarge d: 139 :':4 9 vs. 49:':32 UIl, p = 0.OO6).The increment of
We have recently conducted several second law analyses, including one on a catalytic reformer and two on ethylene plants. This paper summarizes our results from these analyses and presents our conclusions regarding the use of second law analysis for energy conservation studies. First, the methodology we developed to perform a second law analysis is presented. Then, as an example, the lost work distribution in catalytic reforming is tabulated and discussed. Such tabulations spotlight the major contributors to inefficiency in a process (e.g. combustion steps). However, to date, no major inefficiency has been found that can be eliminated using today's technology.