随着我国国防和军队教育改革的不断深化,部队对卫生士官的要求逐渐提高,卫生士官经过正规培养成为优秀卫勤人才是实现强军目标的需要. 在卫生士官实施创伤急救时,特殊的环境要求他们不仅能够消除伤病员身体上的病痛,也要求他们帮助伤病员从精神和心理上得到安慰. 在创伤急救教学中,教员不仅要教授理论及操作技术,还要在教学内容中融入医学人文教育,引导卫生士官从生物、伦理、心理、战场环境等多角度考虑问题,为伤病员提供治疗和预防的全方位处置措施,这样才能培养德技双馨的卫生士官人才,使他们以更出色的能力服务于军队卫生事业,适应平战时工作需要.

威尔斯是19世纪末20世纪初英国著名小说家和社会活动家,为人类社会留下了丰厚的文化遗产.威尔斯创作的科幻小说、社会批评小说、政治理念小说不仅在思想性和艺术性方面大大超越了当时的时代,也体现出明显的社会意义和价值.

Aim To explore the effects of salvianolic acid B(SAB) and tanshinone ⅡA(TA) alone or the compatibility of these two effective components on the proliferation of rat vascular adventitial fibroblasts, and to observe the effects of the compatibility of the two on cell proliferation with the stimuation of angiotensin Ⅱ(Ang Ⅱ).Methods The effects of SAB and TA alone or the compatibility of the two on cell proliferation were detected by methyl thiazolyl tetrazolium(MTT) method, and flow cytometry was adopted to detect cell cycle with or without the induction of Ang Ⅱ.Results It was shown that SAB and TA alone could inhibit fibroblast proliferation in different degree.Through a series of concentration screening, three effective concentrations were obtained respectively and then the inhibition of cell growth was detected by Pairwise compatibilities.The results showed that the compatibility of TA(10-8 mol·L-1) and SAB(10-5 mol·L-1) had the most significant inhibitory effect(P<0.01), and they could inhibit cell proliferation, further flow cytometry was adopted to detect drug effects on cell cycle, the results indicated that the compatibility of SAB and TA mainly blocked the cells in G0/G1 phase.Induced by Ang Ⅱ, the compatibility of SAB and TA group, compared with Ang Ⅱ group, blocked thee cells in G0/G1 phase;and compared with combination of SAB and TA group, it mainly blocked cell cycle in S phase.Conclusion SAB and TA have certain inhibitory effect on fibroblast proliferation, also they could inhibit the proliferation induced by Ang Ⅱ, mainly by blocking the cells in G0/G1 phase.

BACKGROUND/AIMS:Salvia miltiorrhiza (SM) contains four major aqueous active ingredients, which have been isolated, purified and identified as danshensu (DSS), salvianolic acid A (Sal-A), salvianolic acid B (Sal-B) and protocatechuic aldehyde (PAL), totally abbreviated as SABP. Although SM is often used to treat various cardiovascular diseases in traditional Chinese medicine, the efficacy and function of optimal compatibility ratio of SM's active ingredients (SABP) in the prevention and treatment of cardiovascular diseases remain uncertain. This study investigated antihypertensive effect and underlying mechanisms of SABP vs. SM lyophilized powder (SMLP) in spontaneously hypertensive rats (SHR) and to establish the ratio of the optimal compatibility of DSS, Sal-A, Sal-B and PAL in improving cardiovascular functions.METHODS:The SHRs were treated with either SABP or SMLP and their systolic blood pressures (SBP) were monitored. The isolated thoracic aorta of SHRs was segregated for immunohistochemistry, Hematoxylin-Eosin stain and mRNA and protein expression of NOX4, TGF-β1, Col-I, ET-1, α-SMA and Smad7. Moreover, the adventitial fibroblasts (AFs) were isolated and cultured from SD rats' aorta and the reactive oxygen species (ROS) production was determined after SABP or SMLP treatment.RESULTS:SABP, but not SMLP, significantly reduced SBP, which were accompanied by the inhibited morphological changes in the thoracic aorta and the reduced mRNA and protein expression of NOX4, TGF-β1, Col-I, ET-1 and α-SMA, but the increased Smad 7 expression in SHRs. Moreover, SABP also resulted in a decreased ROS production in AFs of SD rats.CONCLUSIONS:These results indicate that SABP, but not SMLP, treatment potently inhibits hypertension through improvements of vascular remodeling and oxidative stress. The present study provides new evidence that the efficacy and function from optimal compatibility ratio of SM active ingredients is much better than its lyophilized powder, which represents a strategy to develop SM's new beneficial effect in improving cardiovascular functions.

Background: Adventitial fibroblasts have been shown to play an important role in vascular remodeling and contribute to neointimal formation in vascular diseases. However, little is known about adventitial fibroblast subpopulations. This study explored the process of isolating rat thoracic aorta adventitial fibroblast subpopulations and characterized their properties following stimulation with angiotensin II (ANG II), a critical factor involved in cardiovascular diseases such as hypertension. Methods: Adventitial fibroblasts were isolated and cultured from rat aorta. Fibroblast subpopulations were individually expanded using cloning ring techniques. Cells were treated with ANG II (10 nM, 100 nM and 1 μM) for 0.5, 1, 1.5, 3, 6, 12, or 24 h, and ANG II-induced proliferation and migration were measured by MTT assay and Transwell. Cells were treated with ANG II (100 nM) in the presence or absence of ANG II receptor antagonists (100 μM), losartan (for AT1) and PD-123319 (for AT2). PreproET-1 mRNA and ET-1 were determined by RT-PCR and ELISA, respectively. Collagen type I was detected by western blotting. Results: Two major fibroblast subpopulations were found in the adventitia, epithelioid-like cells and spindle-like cells; Although ANG II promotes the growth of both subpopulations, epithelioid-like cell proliferation shows dose-dependency on ANG II from 10 nM to 1 μM, while proliferation of spindle-like cells reaches a peak value following 100 nM ANG II stimulation; ANG II stimulation enhanced epithelioid-like but not spindle-like cell migration; ANG II dose-dependently increased the expression of preproET-1 and collagen type I, and enhanced ET-1 secretion in epithelioid-like but not spindle-like cells, effects abolished by the AT1 receptor antagonist, but not with AT2 receptor antagonist. Conclusion: Adventitial fibroblasts are heterogeneous and epithelioid-like subpopulations with high sensitivity to ANG II stimulation may be implicated in the pathophysiological mechanisms of vascular remodeling, reparative processes and cardiovascular diseases.

Objective:To observe the curative effects of the combined application of domperidone, pantoprazole and hydrotalcite tablets in the treatment of bile reflux gastritis ( BRG) and explore the underlying mechanism. Methods:Totally 80 patients with BRG were randomly divided into the treatment group and the control group with 40 cases in each. The treatment group was received panto-prazole, hydrotalcite tablets and domperidone, and the control group was treated by hydrotalcite tablets and domperidone. The efficacy was observed in both groups after 4 weeks. Results:The effective rate of symptom relief in the treatment group and the control group was respectively 92. 5% and 62. 5% (P<0. 05). After the 4 week treatment, the gastritis healing rate in the treatment group was higher than that in the control group (P<0. 05). The improvement of gastric mucosal hyperemia, edema and erosion in the treatment group was better than that in the control group with significant difference (P<0. 05). Cholic acid in gastric juice and gastric acid se-cretion were significantly reduced in both groups after the treatment, while the reduction of gastric acid secretion in the treatment group was more notable than that in the control (P<0. 05). Conclusion:Pantoprazole can be used to control BRG, and the combination of the three drugs shows better efficacy in the treatment of BRG.

Objective Using the therapies of promoting blood circulation and removing obstruction in channels and promoting the circulation of qi to notify kidney , the article is to investigate the clinical curative effects of fal opian tube obstructive infertility caused by stagnation of blood stasis and cellular network impassability. Methods To observe and record the improvements of the main symptoms of 49 out-patient cases, and to take fol ow-up visits and record their fertility situation within two years. Results The combination of prescriptions of promoting blood circulation and removing obstruction in channels and promoting the circulation of qi to notify kidney can greatly improve the symptoms of phlegm muddy blood jam-up certificate. This therap y can improve effectively the symptoms of salpingemphraxis. With 27 cases of curing (55.10%), 14 cases of bettering (28.57%) and 8 cases of ineffectiveness(16.33%), the total effective rate reaches 83.67%. Conclusion The method of promoting blood circulation and removing blood-stasis can improve the symptoms of phlegm muddy blood jam-up certificate and salpingemphraxis.

职业倦怠不仅会影响教师的身心健康,甚至还会影响到教育教学质量。调查结果表明,河北省英语教师正在遭受职业倦怠的侵袭。小学英语教师职业倦怠程度最轻,高中英语教师职业倦怠最为严重。不同层次英语教师之间职业倦怠差异显著。

从实际出发提出了影响专业英语课堂教学与网络自主学习整合顺利进行和实现整合目标的四大误区,并针对这些误区,提出了解决问题的对策和建议,以期能够更准确地把握专业英语课程整合的基本特点与规律,实现课程整合更高层次目标。

高职教育作为一种高等教育新类型,有着与传统学科型教学明显不同的特点.<教育部关于以就业为导向深化高等职业教育改革的若干意见>指出:高职教育应坚持培养面向生产、建设、管理、服务第一线需要的"下得去、留得住、用得上",实践能力强、具有良好职业道德的高技能人才.卫生士官的培养目标是:培养政治坚定信得过、献身国防留得住、技术优良用得上的优秀卫生士官人才.要达到这一培养目标,必须高度重视学员实践能力的培养,外语教学也应如此.

医学英语属于科技英语,其表达方式和用法不同于普通英语。因此,只有在充分了解医学英语特点的前提下才能掌握好医学英语的翻译方法。本文从分析医学英语词汇、语法、句式结构等方面的特点着手来探讨医学英语的翻译方法。

The study analyzed the actuality of medical NCO and the educational and training condition and insufficiency.With our teaching and managing experiences the study was based on the great significance and requirements of NCO education.It tried to perfect the NCO educating system in terms of the primary qualificatory training,the middle and advanced strengthened training,the higher vocational education,continuing education and special training,etc.The revolution was also based on training resource,training contents,teachers construction,teaching methods and the appraisal of craftsmanship so as to improve the educational qualification which may provide reference for the new-staged medical NCO education of PLA.

约翰·邓恩一生写作的爱情诗包括《歌与短歌集》和《哀歌》,在诗中邓恩经过不断的追求和探索,逐渐形成了其成熟的爱情和谐观:基于灵与肉的统一基础之上的男女和谐。而男女和谐也是若干方面的统一:爱情双方的全情投入,爱情的自主性,爱情的排他性,爱情的相互性。邓恩诗歌中对爱情的探讨使他的诗歌超越了当时的时代,是文学爱情主题的进步。

约翰.邓恩经过不断地追求和探索,在其写作的爱情诗集《歌与短歌集》和《哀歌》中表达了他对爱情的和谐期盼:灵与肉的统一,对爱情全情投入,爱情的自主性、排他性和相互性。邓恩诗歌中对和谐爱情的探讨使他的诗歌超越了当时的时代,是文学爱情主题的进步。

海明威是美国二十世纪杰出的作家之一，他一生创作出了很多不朽的经典作品。他所描述的人物有很多都面临精神的困惑与迷茫，但是又都坚韧，顽强，为探寻生活的真谛而不断努力追寻，并逐渐认识到传统的人类中心主义观点使人类变得以自我为中心，过多地关注于自身的物质利益而陷入价值观的颓败和精神的迷乱中。自然界在人类生活中的缺失导致人性的异化，加剧了人类精神生态的不平衡性，因此回归自然是人类重新获得和谐生活的本源，最终能使灵魂得到净化与升华。

<正>教育部2004年颁布的《大学英语课程教学要求》(试行)指出,大学英语的教学目标是培养学生英语综合应用能力,增强其自主学习能力,提高综合文化素养,使他们在今后工作和社会交往中能用英语有效地进行口头和书面的信息

The English poems depicting men's feeling created the images of men pining for wives in the British Renaissance while the Chinese poems depicting women' feeling described the images of women's pining for husbands since the creation of Book of Songs.The men and women described in poems had something in common in their fate: they were deserted and felt lonely,but they did not accept the arrangement of fate.Some of them broke away obstacles and rose against the fate.Through analysis of Chinese and English poems,we can see that there is something in common in the description of the images of lonely men and women.

比较英国文艺复兴时期安德鲁·马维尔的<致他娇羞的女友>和的中国唐代诗人李白的两首诗歌,说明"及时行乐"这一主题在东西方诗歌中的体现.