欧阳俊辉 | AMiner学者主页

全面呈现 [欧阳俊辉] 的学术影响力

深度挖掘高质量成果与权威引用，让优秀看得见

研究兴趣

20222023

论文（7）

专利

基金项目

按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选

1Effects of Application of Nuanqi Powder at Shenque(CV 8)on the Intestinal Micro-ecology and Gastrointestinal Function in Children with Diarrhea due to Spleen Defi-ciency

OUYANG Junhui,LI Fu-gen,HUANG Qian

Objective To explore the clinical value of the application of Nuanqi Powder at Shenque（CV 8）in the treatment of diarrhea due to spleen deficiency in children.Methods A total of 86 children with diarrhea（syndrome of spleen deficiency）treated in the First Affiliated Hospital of Henan University of Chinese Medicine from February 2020 to February 2022 were selected and assigned into control and observation groups（n=43）according to the random number table method.The control group received routine treatment, and the observation group additionally received application of Nuanqi Powder at Shenque（CV 8）.The treatment lasted for 7 days.The time to symptom relief, efficacy, and safety（adverse reactions）were compared between the two groups.The intestinal flora changes and gastrointestinal function indicators[gastrin（GAS）,5-hydroxytryptamine（5-HT）,and vasoactive intestinal peptide（VIP）]were determined before and after treatment.Results The time to the relief of abdominal pain, diarrhea, vomiting and the recovery of normal stool in the observation group was shorter than that in the control group（P＜0.05）.The observation group had higher total effective rate than the control group[95.35%（41/43）vs.81.40%（35/43）,P＜0.05].The treatment in both groups increased the counts of Bifidobacterium, Lactobacillus, and Bacteroides and decreased the counts of Coprococcus, Escherichia coli, Staphylococcus, and Veillonella（P＜0.05）,and the changes in the observation group were more significant than those in the control group（P＜0.05）.The treatment in both groups elevated the GAS level and lowered the 5-HT and VIP levels（P＜0.05）.Moreover, the observation group had higher GAS level and lower 5-HT and VIP levels than the control group（P＜0.05）.Neither group showed severe adverse reactions.Conclusion The application of Nuanqi Powder at Shenque（CV 8）relieved the diarrhea-related symptoms, restored the intestinal microenvironment, and improved the gastrointestinal function in the children with diarrhea due to spleen deficiency and demonstrated high safety.

2023World Journal of Integrated Traditional and Western Medicine（2023）

引用

AI阅读

2Clinical effect of Jingxing Zhike granule combined with acupoint application on children with acute bronchitis and its effect on the levels of CysLTs and MCP-4 in children

Liu Zhen-Feng,Wang Chan,Ouyang Jun-Hui

目的:分析荆杏止咳颗粒联合穴位贴敷对小儿急性支气管炎的临床效果及对半胱氨酰白三烯(Cysteinyl leukotrienes,CysLTs)及单核细胞趋化蛋白4(Monocyte chemoattractant protein 4,MCP-4)水平的影响.方法:选取我院儿科2021年3月至2022年3月间收治的急性支气管炎患儿146例,按照盲法分为对照组和研究组(n=73),分别给予穴位贴敷以及荆杏止咳颗粒联合穴位贴敷治疗.治疗后3 d分析两组患儿临床症状消失时间;采用酶联免疫吸附法测定炎症相关指标,包括肿瘤坏死因子-α(Tumor necrosis factor-α,TNF-α)、超敏C-反应蛋白(Hypersensitive C-reactive protein,hs-CRP)、CysLTs、MCP-4水平;采用肺功能检测仪监测肺功能指标,如潮气量(Tidal volume,VT)、达峰时间/呼气时间(Peak time/expiratory time,tPTEF/tE)、呼吸时间比(Respiratory time ratio,Ti/Te)以及治疗有效率.结果:治疗后研究组患儿临床症状消失时间低于对照组(P<0.05);血清TNF-α、hs-CRP、Ti/Te、CysLTs、MCP-4水平明显低于对照组,VT、tPTEF/tE水平高于对照组(P<0.05);研究组治疗总有效率高于对照组(P<0.05).结论:使用荆杏止咳颗粒联合穴位贴敷对小儿急性支气管炎治疗,能够缓解肺功能,抑制CysLTs、MCP-4水平,临床效果较好.

2022Sichuan Journal of Physiological Sciences（2022）

引用

AI阅读

3Progress in the Treatment of Chronic Milky Moth in Children with External Therapies of TCM

黄甡,欧阳俊辉, 刘然

中医外治法治疗儿童慢性乳蛾的方法有:灼烙法、啄治法、小儿推拿疗法、针刺法等,均有一定疗效,但目前的研究以减轻其并发症、加强术后护理为主,有一定的局限性.今后,应结合现代科学技术,根据中医"治病求本"理念,局部结合全身,充分发挥传统医学的优势.对于大量临床研究的样本量较小等问题,应增大样本量,严格遵循实验研究的随机对照原则,使研究更具统计学意义.探讨内外治结合的治疗方法,寻求最佳治疗效果.

2021Henan Traditional Chinese Medicine（2021）

引用

AI阅读

4Clinical study on the treatment for diarrhea of spleen deficiency type in children by acupoint application of umbilicus-warming powder

Yingsheng SHEN,Yanwei WANG,Sheng HUANG,Junhui OUYANG,Fugen LI,Yue SHE,Jun ZHANG

目的观察暖脐散穴位贴敷治疗小儿脾虚型泄泻的临床疗效.方法选择2019年1月至2020年1月河南中医药大学第一附属医院儿科门诊收治脾虚型泄泻患儿96例为研究对象,随机分为观察组和对照组各48例.观察组用暖脐散穴位贴敷,每日1次,对照组采用常规治疗,干预7d后对疾病的主症积分、腹疼缓解时间、临床疗效及安全性进行统计分析.结果观察组患儿主要症状积分改善明显优于对照组,差异有统计学意义(P＜0.01);观察组患儿腹痛缓解时间优于对照组,差异有统计学意义(P＜0.01);观察组患儿总有效率为97.9％(47/48),优于对照组83.3％(40/48),差异有统计学意义(P＜0.05).结论暖脐散穴位贴敷对小儿脾虚型泄泻有显著的临床疗效.

2020Chinese Pediatrics Of Integrated Traditional And Western Medicine（2020）引用：2

引用

AI阅读

5Effects of Pujin Oral Liquid on Expressions of IL-6 and TNF-α During Lipopolysaccharide-Induced Cerebral Damage in Early Neonatal Rats

Bingxiang MA,Tiantian CHEN,Yang OU

目的:运用蒲金口服液对宫内感染/炎症致早产脑损伤大鼠进行干预,通过观察炎性细胞因子肿瘤坏死因子-α(tumor necrosis factor alpha,TNF-α)和白细胞介素-6(interleukin-6,IL-6)在脑组织中的表达,探讨蒲金口服液在治疗脑性瘫痪中的作用.方法:将24只脂多糖(LPS)组和6只对照组孕鼠分别在孕第16、17天连续腹腔注射LPS 350μg/kg和等量生理盐水.后将LPS组的80只早产仔鼠随机分为早期药物干预组A1、B1、C1、D1,分别对应蒲金口服液低剂量组、蒲金口服液高剂量组、银杏叶提取物组,模型组.和晚期药物干预组A2、B2、C2、D2,分别对应蒲金口服液低剂量组、蒲金口服液高剂量组、银杏叶提取物组,模型组.早期药物干预组生后0日龄灌胃给药,晚期药物干预组生后7日龄灌胃给药,均连用7d.干预后同条件饲养至21日龄.通过免疫组化的方法检测脑组织中IL-6和TNF-oα的表达.结果:早期药物干预组中,与D1相比,A1、B1、C1均能明显下调仔鼠脑组织中IL-6和TNF-α的表达(P＜0.05).B1下调IL-6和TNF-α表达的作用优于A1和C1(P＜0.05),晚期药物干预组中,与D2相比,A2、B2、C2均能明显下调仔鼠脑组织中IL-6和TNF-α的表达(P＜0.05).B2下调IL-6和TNF-α表达的作用优于A2和C2(P＜0.05),且C2的作用优于A2.与晚期药物干预组相比,早期干预组效果更明显.结论:蒲金口服液可改善宫内感染/炎症所致早产脑损伤,其机制可能与下调脑组织中IL-6及TNF-α的表达有关,且早期药物干预下调作用更明显.

2018Liaoning Journal of Traditional Chinese Medicine（2018）引用：3

引用

AI阅读

6Clinical Research of Electricacupuncture at Sishen Points on Improveing the Infantile Cerebral Palsy with Mental Retardation

Suzhen GUO,Bingxiang MA,Yuxiang YE,Junhui OUYANG

目的观察电针四神针治疗脑性瘫痪合并智力障碍的临床疗效.方法将符合纳入标准的72例脑瘫合并智力障碍患儿随机分为治疗组和对照组,2组各36例.2组均进行头皮针灸、药物、PT、OT、理疗等康复训练,治疗组加用电针四神针治疗.3个月为1疗程,共治疗1个疗程.治疗结束后观察2组智力提高效果.结果治疗组和对照组患儿在治疗前后智力测试均有所提高.治疗后,治疗组和对照组在智力测试方面比较,差异有统计学意义(P＜0.05).2组临床疗效比较,治疗组显效18例,有效15例,无效1例.对照组显效11例,有效17例,无效3例,2组比较差异有统计意义(P＜0.05).结论电针四神针对于治疗脑瘫合并智力障碍患儿有更好疗效,能够有效改善患几的认知能力.

2017Chinese Medicine Modern Distance Education of China（2017）引用：2

引用

AI阅读

7Literature Research on Acupuncture in the Treatment of Children Autism Spectrum Disorder

Junhui OUYANG,Tiantian CHEN,Bingxiang MA

目的评价并总结针刺治疗孤独症的临床试验文献.方法通过机检全面收集近10年来针刺治疗孤独症的临床治疗文献,按照中国循证医学中心推荐的标准,分析评价每一篇文献.结果缺乏高质量的临床治疗试验文献,针刺取穴和针刺方法种类迥异,无确定的选穴原则.结论针刺治疗孤独症疗效真实可靠,治疗规范有待进一步完善.

2016Chinese Medicine Modern Distance Education of China（2016）引用：10

引用

AI阅读