Abstract Social stigma surrounding chronic skin Ulcer leads patients to hide their wounds or delay seeking medical care. The aim of this study was to explore the types and causes of chronic skin ulcers among patients seen in the dermatology departments of two university hospitals in Burkina Faso. This was a cross-sectional, retrospective study covering an 11-year period, from 2013 to 2023. A review of consultation records allowed for the collection of sociodemographic and clinical data from 104 patients who were seen for chronic skin ulcers over the 11-year period, averaging 9 patients per year. The patients were primarily adults (n=60) and older adults (n=21). Leg ulcers were the condition observed in most patients (n=59). Eight cases of Buruli ulcer (7.69%) were identified among the 104 patients. Five of the eight cases, or 62.50%, were aged between 0 and 19 years. Half of the eight patients resided in Ouagadougou. These results highlight low utilization of dermatology services for chronic skin ulcers. Furthermore, indigenous cases of Buruli ulcer have been identified in Burkina Faso. Consequently, our findings call for the implementation of strategies focused on addressing social perceptions of these ulcers and on the screening and management of this disease.

Fibrodysplasia ossificans progressiva, also known as Münchmeyer's disease, is a rare autosomal dominant genetic disorder characterized by progressive heterotopic ossification, ultimately resulting in a "stone man" phenotype. We present the case of a male infant who exhibited musculocutaneous manifestations during the neonatal period.

Background:The keloids scar is a skin scarring pathology with a higher frequency in the black population. Several genetic polymorphisms, including those of transforming growth factor receptors, have been identified as probable susceptibility genes. This study aimed to characterize the polymorphisms of TGF-βRI, TGF-βRII and identify risk factors associated with keloid scars in Burkina Faso. Methods:This was a cross-sectional study that included 141 subjects with keloids and conducted from April 2021 to April 2022. Genomic DNA was extracted using the "PureLinkTM Genomic DNA Mini kit". Genotyping of TGF-βRI rs111854391, rs121918710, and TGF-βRII rs104893807, rs28934568 polymorphisms was performed using real-time PCR. Results were considered statistically significant at p<0.05. Results:The average age of the study population was 34 ± 15 years and O Rhesus positive blood group (O+) was predominant (36.88%). All subjects (100%) were heterozygous (TG) for rs121918710. Medical or surgical history, family history, blood type, and rs28934568 polymorphism were related to the number of sites of keloids on the body. Patients with a medical history (9.8%) were carriers of the mutant allele C for rs28934568. Mossi ethnic had more than 8 times risk of developing a keloid scar (p=0.030; OR=8.66 (95% CI: 1.230-60.902). Conclusion:The presence in all the patients of the mutated allele for the rs 121918710 polymorphism could explain the involvement of this mutation in the occurrence of keloid scars. In addition, ethnicity and blood type were the risk factors associated with keloids.

ABSTRACT Lipomas are usually benign tumors formed from a proliferation of mature adipocytes, resulting in hypodermic, soft, compressible, and mobile nodular formations under the skin. In their subcutaneous location, superficial lipomas represent 16% to 50% of soft tissue tumors. They may be solitary or multiple. Solitary lipoma is usually seen in young adults between the ages of 30 and 50 years, regardless of sex, and is frequently asymptomatic. A lipoma is called giant when its weight exceeds 1 kg or its diameter exceeds 5 cm. The etiopathogenesis of lipomas is poorly understood. Herein, we report a case of giant pedunculated lipoma localized on the left inguinal fold being a distress for the patient. Key words: Giant pedunculated lipoma, Diagnostic wandering, Ablation, Burkina Faso

Kaposi’s sarcoma is a multifocal angiogenic tumor disease whose principal causal agent is human herpes virus 8 (HHV-8). Herein, we report a rare case of iatrogenic Kaposi’s sarcoma developing during oral corticotherapy. A 76-year-old, HIV-negative male presented with papulous, angiomatous lesions on the trunk and limbs, which appeared three months after the beginning of oral corticotherapy for bullous pemphigoid. We suspected iatrogenic Kaposi’s sarcoma given the time to lesion onset in relation to the immunosuppressive treatment, together with histological and virological confirmation of HHV-8. The lesions began to subside when corticosteroids were tapered down to 10 mg/day. This was the first case reported in our setting and it emphasized the need for the rigorous monitoring of patients receiving immunosuppressants to avoid overlooking the side effects or rare complications of these treatments. Key words: Kaposi’s sarcoma; Oral corticotherapy; HHV-8; Bullous pemphigoid

Introduction: The prevalence of urticaria is increasing. Approximately 20% of individuals have suffered from an acute episode of urticaria at least at some point in their lives. The objective of this study was to evaluate the clinical and therapeutic socio-demographic profile and quality of live of patients followed for urticaria in the dermatology-venereology department of the Yalgado Ouédraogo University Hospital in Ouagadougou. Methodology: We conducted a descriptive cross-sectional study over a 5-year period from 1 January 2015 to 31 December 2019. The data were collected retrospectively by analysing the files and prospectively by evaluating the quality of life with DLQI. All the records of patients treated for urticaria at the Dermatology-Venerology Department of the Yalgado Ouédraogo University Hospital during the period were included. Results: Urticarial frequency is 1.91%. There were 36 men (25.71%) and 104 women (74.28%), i.e. a sex ratio of 0.34. The median age was 31 years with extremes of 4 to 70 years. The 30 - 45 age group accounted for 51.42%, followed by the 16 - 29 age group (31.42%), then the 46 - 65 age group (9.28%), the 4 - 15 age group (5.71%) and the over 66 age group (2.14%). In terms of occupation, pupils/students accounted for 37.1%, housewives for 18.6% and workers for 44.3%. As for the residence of the patients, 88.57% lived in Ouagadougou Personal history of atopy, it concerned 19.26% of patients, with precisely 9.28% having asthma history, 7.14% having rhino-sinusitis history, 1.42% of atopic dermatitis and allergic conjunctivitis respectively. For clinical aspects, 97.14% of the patients had superficial urticaria, and 2.86% had facial angioedema. There were 35% (49) patients with acute urticaria and 65% (91) with chronic urticaria. Chronic urticaria was spontaneous in 55% (50) and physically inducible in 10% (9) (sweating, pressure or friction). 97.14% of patients received antihistamines associated with systemic corticoids in 2.86%. For Quality of life, the mean DLQI score was 7.51, indicating a moderate effect of urticaria on patients’ quality of life. The quality of life of women was more affected than that of men, especially in the professional and social spheres. Conclusion: In hospital frequency of urticaria is low in Ouagadougou, a predominance of chronic spontaneous urticaria whose management involves the use of second generation antihistamines at a dosage and duration that do not meet international recommendations. The patients’ quality of life was moderately impaired.

Abstract Background and objectives Skin cancers in albinos are frequent in sunny countries. The surgeon plays a crucial role in their treatment. The objective was to describe the challenges of surgical management of skin cancer in albinos. Methods Retrospective, descriptive, and multicenter study on skin cancer surgery in albinos performed over the past 14 years in Ouagadougou. We were interested in surgery indications, techniques, and results. Survival was assessed using the Kaplan–Meier method. Comparisons of proportions were made by Student’s t-test. Results The cancers were multiple synchronous in 41.3%. We identified 46 albinos with 71 skin cancers. Surgery was performed in 93%. Lesions were located on the back, upper limbs, and head and face in 40.9%, 30.3%, and 16.7%, respectively. Precancerous lesions were treated concomitantly in 23.6%. The surgery consisted of a lumpectomy. Direct suturing and mobilization of flaps allowed skin coverage in 17.9% and 34.3%, respectively. Lymph node dissection was associated with the limbs in 73.1% of localizations. The average number of lymph nodes removed was 11, with extremes of 7 and 14. Node invasion was noted in 16 out of 19 cases. The resection margins were invaded in 7.5% and required surgical revision. Recurrences were noted in 8.9% of cases. Overall 2-year survival rate was 55.8%. Conclusions Surgery must meet the triple challenge of treating single or multiple synchronous cancers, precancerous lesions, and allowing good healing. Early diagnosis would reduce the rate of secondary healing and improve survival. The absence of extemporaneous histology and the large size of the tumors associated with the delay in diagnosis meant that surgery, whenever possible, was limited to wide and deep resection, to ensure healthy margins.

Introduction : Le but de cette étude était de déterminer les facteurs associés à la survenue de chéloïde chez les patients consultant au service de Dermatologie du Centre Hospitalier Universitaire de Ouagadougou du 1er janvier au 31 décembre 2014. Méthodes : Il s’est agi d’une étude longitudinale descriptive, la première partie rétrospective, la seconde partie prospective (les patients revus lors du suivi). Résultats : Sur les 2164 dossiers recensés en 2014, 76 patients étaient porteurs de cicatrices cutanées, soit une prévalence hospitalière de 3,51% , mais 52 patients revus au suivi ont été retenus. Chez les 52 patients étaient dénombrés 330 cicatrices cutanées dont 173 cicatrices non chéloïdiennes et 157 cicatrices chéloïdes. L’âge moyen des patients était de 32,15 ans. Le sex ratio était de 0,57. Un antécédent familial de cicatrice chéloïdienne a été retrouvé chez 13 patients. L’infection cutanée et les traumatismes (écorchures) étaient les principales circonstances de survenue. Le thorax était le siège électif des chéloïdes. Les chéloïdes étaient survenues dans la période post pubertaire chez 70,06% des patients. Toutes les chéloïdes étaient prurigineuses contrairement aux cicatrices non chéloïdiennes et 13,5% des cicatrices chéloïdiennes étaient douloureuses. La taille des chéloïdes était supérieure à 4 cm dans 68,15%. Les chéloïdes ont négativement affecté la qualité de vie de 27 patients sur 52. Conclusion : Les chéloïdes affectaient plus les femmes, et survenaient volontiers au décours d’un traumatisme en période post-pubertaire, siégeant sur des zones de fortes tensions cutanées, avec des symptômes altérant leur qualité de vie

Background: Dermatitis herpetiformis is a rare autoimmune bullous dermatosis that predominantly affects Caucasians, adults or children, with a sex ratio of 1.8. Materials and Methods: The aim of this study was to document the clinical and epidemiological profiles of dermatitis herpetiformis and to detail its treatment in a hospital setting in order to increase our knowledge about this disease in our context and so to improve its management. We conducted a retrospective, cross-sectional study of the records of all patients seen in consultation or hospitalized at the dermatology department of Yalgado Ouédraogo University Hospital Centre, Ouagadougou, a public hospital in Burkina Faso, from January 2016 to December 2020. Results: We collected 14 cases (0.12%) of dermatitis herpetiformis among 11,456 patients seen. The mean age was 8 years (ranging from 4 to 27 years). The sex ratio was 1.33. The majority of the patients were schoolchildren living in rural areas (8 cases). The duration of the disease ranged from five days to one year (mean duration: 59.35 days). Eight patients had a history of digestive problems such as abdominal pain and diarrhea. Pruritis was the principal functional sign. In all patients, the lesions were polymorphous: disseminated vesicular bullae, papules, erosive, and excoriated lesions, sometimes forming clusters. Mucosal involvement was rare (3 cases). A gluten-free diet and dapsone 2 mg/kg/day were proposed to all patients and resulted in the improvement of the lesions. Conclusion: Our study confirmed that dermatitis herpetiformis is rare in our context. It is more frequent in young children and predominantly affects boys. It is intensely pruritic, and generalized polymorphous lesions were present in all our patients. Treatment is essentially based on a gluten-free diet and dapsone, which is a therapeutic test in the absence of supplementary investigations to establish a definitive diagnosis. Key words: Dermatitis Herpetiformis; Clinical Medicine; Dapsone; Gluten Intolerance

Cutaneous tuberculosis is a rare, extra-pulmonary form of tuberculosis caused by mycobacteria of the tuberculosis complex. It is characterized by clinical polymorphism often posing a difficult diagnostic challenge. Herein, we report a case of cutaneous tuberculosis in its warty form located on the nose. This was a 57-year-old patient who was infected in the classroom three months previously while taking lessons from a woman with pulmonary tuberculosis. A facial examination revealed a blackish, papillomatous patch invading almost the entire nose, with a keratotic surface spreading over the wings of the nose. The diagnosis of verrucous tuberculosis was reached on the basis of epidemiological, clinical, and paraclinical arguments. Under anti-tuberculosis treatment for six months, the lesion had healed without sequelae. The diagnosis of verrucous cutaneous tuberculosis must be established in the presence of any chronic and crusty lesion. The management responds to the treatment protocol for all forms of tuberculosis.

Background: Psoriasis is a chronic, displaying inflammatory dermatosis. The evaluation of the psychosocial impact of chronic dermatoses on the quality of life of patients may help to orientate the objectives of management in order to improve their daily life, hence the interest of our study with the objective to evaluate the impact of psoriasis on the quality of life of patients followed in the dermatology, venereology, and rheumatology departments of the city of Ouagadougou, Burkina Faso. Patients and Method: This was a descriptive, cross-sectional study that took place from March 1 to June 28, 2019, in six public hospitals in the city of Ouagadougou. The Dermatology Life Quality Index (DLQI) and Psoriasis Disability Index (PDI) were the quality of life tools employed for this study. Results: Forty-eight (48) patients with psoriasis met the inclusion criteria. The mean age of the patients was 46.20 years, ranging from 22 to 79 years. There were 18 females and 30 males, with a sex ratio of 1.6. The measurement of the patients’ QoL by the DLQI reported a mean score of 9.14 out of 30. There was a low impact of the disease on the QoL for seventeen patients. The evaluation of the QOL with the PDI noted an alteration of daily activities (3.95/15) and alteration of the patients’ psychosocial relationships (2.66/18). The analysis of the QoL according to sociodemographic and clinical variables noted an alteration significantly related to age, level of education, and severity of the disease. An alteration in professional relationships was significant in female patients. An alteration in the different dimensions of the QoL was more significant in patients with a low level of education. The duration of the disease seemed to have no impact on the patients’ quality of life. Daily activities were significantly altered for patients with a PASI between 7 and 10. The DLQI did not correlate with disease severity (PASI) (r = 0.228; p = 0.120), unlike the PDI (r = 0.371; p = 0.009). Conclusion: The QoL of psoriatic patients in Ouagadougou seemed to be slightly altered. This alteration was more significant for females. Professional relationships were altered for young subjects while daily activities were altered for those older.

Background: Healthy skin with integrity is essential for maintaining one’s physical, mental, and social wellbeing. Vitiligo, a chronic autoimmune dermatosis characterized by asymptomatic, achromic macules, affects the integrity of the skin. Methodology: This was a descriptive, cross-sectional study conducted from March to June 2019 in six public hospitals in the city of Ouagadougou, Burkina Faso. The patients included in the study were followed in the dermatology departments of these structures for vitiligo, aged at least eighteen years and consenting. The Dermatology Life Quality Index (DLQI) and the vitiligo-specific health-related quality of life scale (VitiQoL) were employed to measure QoL (quality of life). Results: A total of fifty patients agreed to participate in the study. The mean age was 40.56 years, ranging from 18 to 79 years. There were as many females as males (25), and 23 married patients out of the fifty. The majority of the patients (43/50) resided in urban areas. Twenty-six patients had at least secondary education and eighteen patients worked in the informal sector. The average duration of vitiligo progression was 10.56 years, ranging from three months to 49 years. The evolution of vitiligo was stationary for 17/50 patients. The lesions were mainly located on the head and neck. The average body surface area (BSA) affected was 12.04%, ranging from 1% to 82%. The treatment was mainly local and general corticosteroid therapy. The evaluation of the patients’ quality of life (QoL) by the DLQI (Dermatology Life Quality Index) yielded a mean score of 5.44/30. Vitiligo had a small effect on the QoL of eighteen patients and a moderate effect on sixteen patients. VitiQoL assessment yielded a mean total score of 32.32/96 and stigma had the highest score of 18.04/36. The patients’ QoL was influenced by age and body surface area affected by vitiligo. Restriction of participation in activities and changes in the patient’s behavior were significantly correlated with the duration of vitiligo progression, followed by stigma, which was related to vitiligo progression. Conclusion: The alteration of the QoL of the patients with vitiligo was low to moderate. This alteration was related to the stigmatization by one’s environment.

Introduction:Human herpesvirus type 8 (HHV-8) is the main etiological agent of Kaposi's sarcoma. This virus is frequently associated with immunocompromision. This study aimed to detect HHV-8 in people with compromised immune system.Patients and Methods:This is a cross-sectional study that included 180 subjects: 179 HIV-infected patients and 1 patient with bullous pemphigoid. Blood samples were taken from all subjects, and swabs of lesions were then taken from individuals with symptoms of Kaposi's sarcoma. Viral load and CD4+ T lymphocytes count were performed for persons living with HIV and real-time PCR detection of HHV-8 DNA was performed in all subjects in the study.Results:Among HIV-infected persons, 13.41% had a viral load of more than 10,000 copies/mL, and 22.91% had a CD4+ T lymphocytes count of fewer than 350 cells/µL. A total of four (three HIV-1 infected patients and one patient with bullous pemphigoid) patients (2.22%) had apparent lesions of Kaposi's sarcoma. In the plasmas and swabs from associated lesions, HHV-8 DNA was found in only two individuals, with an HHV-8 prevalence of 1.11% (2/180) with 0.55% (1/179) in an HIV-infected patient on antiretroviral therapy.Conclusion:These results exposing low prevalence levels of HHV-8 in HIV-infected patients could be due to the beneficial effect of antiretroviral drugs.

Background: The aim of this study was to describe the epidemiological, clinical aspects, and outcome of necrotizing fasciitis (NF) in sub-Saharan Africa. Patients and Method: We conducted a descriptive study in hospital dermatology departments in five sub-Saharan African countries over a two-year period (April 2017 to July 2019). Patients over fifteen years of age received for NF were included. Results: During the study period, 224 patients with NF were included. Their mean age was 51.9 ± 18.3 years and their sex ratio (M/F) was 1.3. NF was present in the lower limbs in 88.8% (n = 199) of the patients. The main local signs of NF were cutaneous necrosis (83.9%; n = 188) and spontaneous intense pain (75.9%; n = 170). NSAIDs (32.6%; n = 73), obesity (16.5%; n = 65), the use of decoctions/poultices (21.4%; n = 48), diabetes (16.5%; n = 37), nicotine addiction (11.6%; n = 26), alcoholism (8%; n = 18), voluntary cosmetic depigmentation (6.7%; n = 15), and HIV infection (3.8%; n = 8) were the main comorbidities. We recorded 14.7% (n = 33) of deaths. Conclusion: This study shows that NF of the lower extremities is the most often observed clinical form in sub-Saharan Africa. Some factors or comorbidities (diabetes, obesity, alcoholism, nicotine addiction) seem to be relatively frequent.

BACKGROUND:In developing countries, the long delays in consultation lead to a delay in diagnosis and management of the skin tumors. The lesions are often large and bring the problem of skin coverage after their resections. Several reconstruction techniques allow skin coverage. The objective of this study is to describe the place of O-to-Z technique in the surgical treatment of skin cancers in Ouagadougou. We hypothesized that O-to-Z technique reduces healing times and the number of dressings compared with directed wound healing.PATIENTS AND METHODS:It was a two-center, retrospective, descriptive study on O-to-Z technique in skin cancers. It included patients who underwent surgery between January 1st, 2013 and March 30th, 2021 in Ouagadougou. Scar quality and healing time in Z-plasty were compared with those of secondary healing. We used the Student's t test.RESULTS:In 8 years and 3 months, 171 skin cancers were identified. The mean time to consultation was 13.6 months. The average size of the tumors was 9 cm. An O-to-Z technique was performed in 42 cases, being 58.3% of the patients operated on. The average healing time was 15 days. It was four and a half times shorter in O-to-Z technique than in secondary healing. Ischemic necrosis of the Z-corner was noted in 7 cases. The recurrence rate in O-to-Z technique and secondary healing was 7.1% and 9.1% respectively. Hypertrophic or keloidal scars were noticed in 7 cases and hypochromia in 2 cases.CONCLUSION:O-to-Z technique is a technique of choice for skin coverage after large resections in surgical oncology. It reduces the healing time and the cost of postoperative care without increasing the risk of tumor recurrence.

INTRODUCTION: Au Burkina Faso, le seul foyer de leishmaniose cutanée (LC) avec confirmation biologique dans la littérature à notre connaissance est celui de Ouagadougou au centre. Nous rapportons les résultats épidémiologiques, cliniques et biologiques de l´investigation d´un nouveau foyer épidémique à Larama, à l´ouest du Burkina. METHODES: la méthode du camp a été utilisée pour recevoir les cas. Les données sociodémographiques et cliniques ont été recueillies à l´aide d´un questionnaire. La confirmation a été faite par la microscopie puis par réaction en chaîne par polymérase (PCR). RESULTATS: au total, 108 cas suspects ont été recensés à Larama, soit un taux d´attaque de 5,8%. Le sex ratio était de 1,08. Les patients concernés étaient le plus souvent des cultivateurs (35,2%) et des commerçants (33,3%). La population active (15 à 49 ans) représentait 51,9%. Le nombre de lésion variait entre 1 et 5 dans 91,7% des cas. Les lésions qui se présentaient sous formes ulcéro-crouteuses surélevées et infiltrées, étaient localisées sur les membres (87%) avec une durée d´évolution entre un et cinq mois dans 96,3% des cas. Sur les deux cas prélevés, la microscopie a montré des leishmanies et la PCR a confirmé l´espèce Leishmania major. CONCLUSION: nos résultats confirment l´existence d´une épidémie de leishmaniose cutanée à L. major dans l´ouest du pays. Des enquêtes complémentaires sont nécessaires pour préciser la charge de morbidité des leishmanioses au Burkina Faso.

Introduction: in Burkina Faso, the only epidemic focus of cutaneous leishmaniasis confirmed in the literature by lab tests was in Ouagadougou. We report the epidemiological, clinical and biological results of the assessment of a new epidemic focus in Larama in western Burkina Faso, Methods: camps were used to receive patients, Sociodemographic and clinical data were collected using a questionnaire. Confirmation was based on microscopy and polymerase chain reaction (PCR). Results: a total of .108 suspected cases have been identified in Larama, reflecting an attack rate of 5.8%. Sex ratio was 1.08. The patients were most often farmers (35.2%) and traders (33.3%), The working population (15-49 years old) accounted for 51.9%. The number of lesions varied between 1 and 5 in 91,7% of the cases. The lesions manifested as raised and infiltrated ulcerative lesions on the limbs (87%) with evolution ranging from 1 to 5 months in 96.3% of the cases. Samples were collected from two patients; microscopy showed leishmanias and PCR confirmed Leishmania major. Conclusion: our results confirm the presence of a cutaneous leishmaniasis major outbreak in the western part of the country. Additional surveys are needed to clarify the burden of leishmaniasis in Burkina Faso.

Loa loa filariasis is usually found in the forest areas of Central and West Africa. We report a case that was diagnosed in Ouagadougou (Burkina Faso), a savanna area. The patient lived in Gabon but was visiting his family in Ouagadougou. He complained of fatigue, fever, itchy legs with scratch marks, and intermittent edema of the legs. A blood smear was first examined for malaria parasites, but Loa loa microfilariae were observed. Laboratory tests showed hypereosinophilia (30%). Transient angioedema (Calabar edema) was observed. Loa loa filariasis was diagnosed based on these findings. There were no other laboratory test abnormalities, and ophthalmological examination was normal. The patient received a single dose of ivermectin at 200 µg/kg. After 1 month, the patient's course was favorable and a control blood smear was negative.

RESUME Introduction. La presente etude pilote avait pour but de determiner la frequence des albinismes oculocutanes (AOC) en population, les pathologies observees et l’offre de soins aux personnes atteintes d’albinisme (PAA) dans la commune rurale de Lena, a l’Ouest du Burkina Faso. Methodologie. Il s’est agi d’une etude descriptive transversale a collecte prospective, portant sur les albinos et les agents de sante de la commune rurale de Lena durant le mois d’avril 2018. Les albinos ont ete soumis a un questionnaire, puis a un examen dermatologique et ophtalmologique. Les agents de sante ont repondu a un questionnaire. Resultats. D’une population de 23217 habitants, 31 albinos ont ete inclus, soit une frequence de 1,34/1000. L’âge moyen des albinos etait de 19,6 ans et le sex-ratio de 0,8. Toutes les PAA avaient au moins une manifestation ophtalmologique et 83,9% avaient des manifestations dermatologiques. Sur 45 agents de sante inclus, aucun n’avait recu une formation sur l’albinisme et tous etaient disposes a prendre en charge les PAA. Conclusion. Les AOC sont frequents dans la commune rurale de Lena. La morbidite elevee contraste avec le manque de competence du personnel de sante. Des efforts restent donc a faire pour une prise en charge holistique de la personne albinos. ABSTRACT Backgrounds. The purpose of this pilot study was to determine the population-based prevalence of Oculocutaneous albinism (OCA), pathologies observed and care provision to persons with albinism (PWA) in the rural municipality of Lena in western Burkina Faso. Methodology. We conducted a prospective cross-sectional descriptive study on PWA and health workers in the rural municipality of Lena during April 2018. PWA were subjected to a questionnaire, dermatological and ophthalmological examination. Health workers responded to a questionnaire. Results. Among 23217 inhabitants, 31 PWA (1.34 / 1000) were included. The average age of PWA was 19.6 years and the sex ratio was 0.8. PWA do not have good knowledge of albinism and 35.5% use the means of cancer prevention. All PWA had at least one ophthalmologic manifestation and 83.9% had dermatologic manifestations. Of 45 health workers included, none had received training in albinism and all were willing to take care to PWA. Conclusion. OCA are common in the rural municipality of Lena. High morbidity contrasts with the lack of competence of health workers. Efforts remain to be made for a holistic management of PWA.