AIM:To investigate the expression of Fas/FasL in fetal cornea after deep cryopreservation.METHODS: Immunohistochemical SABC method was used to study the expression of Fas/FasL in paraffin-embeded sections of 33 fetal corneae, including both nomal fetal corneae and cryopreserved corneae.RESULTS: All fetal corneal cells Fas/FasL was stained in cytoplasm and cell membrane. The positive expression of Fas protein was detected in all the 33 fetal corneae, so was FasL protein. Fas protein was expressed in corneal epithelial, stromal and endothelial cells. FasL ligand protein, however, was detected in corneal epithelial and endothelial cells, but not in stromal cells. There were no differences in expression of Fas/FasL in either normal fetal corneae or cryopreserved corneae.CONCLUSION: Cryopreservation of fetal cornea does not affect the expression of Fas protein or Fas ligand protein.

单纯疱疹病毒性角膜炎(herpes simple keratitis,HSK)是眼科常见多发病,病程长,反复发作,可严重危害患者视力,其致盲性居角膜病首位[1].多年来,我们采用自治中药"消翳散"结合西药治疗81例单纯疱疹病毒性角膜炎患者,与80例单纯西药治疗相比,其疗效显著.报告如下.

Objective To investigate the distribution of the ophthamopathy of 1 572 inpatients in 2006 in department of ophthalmology,Yantai Yuhuangding hospital.Methods Genders,ages,the first diagnosis of ophthalmic inpatients 2006 were collected and analyzed by stata 8.0.Results During 2006,the top-six oph- thalmopatby of inpatients were cataract,vitreous body and retinal disease,ocular trauma,glaucoma,strabismus and corneal disease.There was difference in both genders and ages.The percent of inpatients aged 40 to 80 year old was 66.03%.The percent of man inpatients (57.70%) was more than that of woman inpatients (42.30%). Conclusion Cataract,vitreous body and retinal disease,ocular trauma,glaucoma,strabismus and corneal dis- ease are the major of ophthalmic inpatients.

1991年来我院曾用Nd:YAG激光治疗原发性闭角型青光眼取得了满意的效果.但术中虹膜易出血,有时不能一次透切,需多次完成,且易伤及角膜内皮.近年来我们联合应用氩/氪离子激光与Nd:YAG激光联合行虹膜周边切除术治疗原发性闭角型青光眼161眼,取得了良好的治疗效果。

目的:观察累及黄斑部视网膜分支静脉阻塞病人发病1～2个月进行早期激光治疗效果.方法:临床观察30例30眼累及黄斑部视网膜分支静脉阻塞病人进行早期氩激光视网膜光凝治疗的临床效果,并与30例30眼药物治疗组病人进行对比.结果:治疗后3个月复查,视力:治疗组,增进者27眼,无变化2眼,下降1眼;对照组,增进者18眼,无变化6眼,下降6眼.视网膜出血吸收情况:治疗组,Ⅱ度以上吸收者27眼(90.1%),Ⅳ度吸收者4眼(13.3%);对照组分别为15眼(50.0%)和1眼(3.3%).黄斑水肿消退:治疗组26眼,对照组9眼.新生血管出现:对照组2眼,治疗组无新生血管出现.结论:对危及黄斑部视网膜分支静脉阻塞病人早期行视网膜激光光凝治疗,可促进视力时恢复和视网膜下出血吸收及黄斑水肿的消退,预防新生血管和玻璃体出血的发生.

黄斑部视网膜前膜(idiopathic macular epiretinal membrane)为视网膜前表面在多种因素作用下发生的细胞增殖,老年人发病较多,青年人亦有患病者,儿童发病较少,本组患儿均为远视伴弱视或斜视,在治疗过程中出现黄斑前膜,报告如下.

视网膜分支静脉阻塞(BRVO)是常见的视网膜血管性疾病,其影响视力的主要原因是黄斑水肿、黄斑部视网膜萎缩、新生血管形成,导致反复玻璃体出血.我们对发病1～2个月累及黄斑部的BRVO患者行氩激光视网膜光凝治疗,与用药物治疗者比较疗效满意,现报告如下. 1 资料与方法 将60例(60眼)BRV O发病1～2个月、经眼底荧光血管造影(FFA)检查有黄斑部荧光素渗漏者随机分为两组.治疗组男17例、女13例,年龄40～78岁、平均58.2岁;病变位于右眼18 例,左眼12例;阻塞部位在颞上分支18例,颞下分支12例.对照组男16例、女14 例,年龄35～74岁、平均57.7岁;病变位于右眼16例,左眼14例;阻塞部位在颞上分支19例,颞下分支11例.

患儿男，2岁，因左眼睑被铅笔尖刺伤15天，眼睑红肿伴体温升高12天，于1997年8月11日急诊入院。患儿入院前曾在当地医院静滴红霉素治疗不见好转。入院体检：体温39.2℃，脉膊112次/分，体重10kg，心肺听诊无异常，肝脾不大。眼科检查：右眼正常。左眼上睑高度红肿，睑裂不能睁开，上睑中部近眉弓处可见条状愈合的皮肤疤痕，该处皮下见黑色粉末状物少许。左眼球轻度前突，眼球各方向运动受限；眶压高；球结膜充血轻度水肿，角膜透明，瞳孔对光反应灵敏，因眼睑肿胀眼底未能查。实验室检查：白细胞23×109/L，中性粒细胞0.817，淋巴细胞0.183。入院诊断：左眼眶蜂窝织炎。

中心性浆液性脉络膜视网膜病变(CSC)是眼科临床常见的眼底病变,好发于青壮年男性,发病原因不明.尽管本病有自愈倾向,且预后相对较好,但部分患者由于病情迁延不或反复发作,常年被视力障碍所困扰,严重影响身心健康和工作.因此,CSC是临床上不可忽视的眼病.目前多采用激光光凝治疗,但由于激光设备价格昂贵,另由于部分患者渗漏点位于黄斑中心,不适宜光凝治疗,因此临床不能普遍开展.为探索对CSC的治疗途径,作者自1 992以来采用高压氧(HBO)治疗配合中药煎剂内服治疗CSC患者63例(68只眼),取得较为满意效果,总结如下.

患者女,65岁.右眼视物不清1年,高血压3年,"蛋白尿"半年.1年前曾在某医院诊断为"右眼视网膜分支静脉阻塞"并静脉滴注"脉络宁"等,视力无明显好转.

Stargardt 氏病为青少年遗传性黄斑变性,临床比较少见,为常染色体隐性遗传。其临床特点为双眼发病,视力进行性减退,色觉障碍,有绝对性或相对性中心暗点,黄斑部横椭园形萎缩,眼底荧光血管造影对该病的早期诊断及研究可提供有价值的资料,现将我院自1984年至1990年遇见8例16眼