Objective:To discuss the protective effect of quercetin on renal injury induced by non-crystal hyperuricemia.Methods:Male adult wistar rats were randomly assigned into three groups: control group,model group and treatment group.Daily gavage with oxonic acid at a dose of 750 mg/kg body weight was used to build non-crystal hyperuricemic rat models.Rats in the treatment group received oxonic acid as manner as model group,simultaneously they were given quercetin at a dose of 150 mg/kg body weight daily by gastric gavage.The experiment lasted for five weeks.Biochemical and pathology study were carried out.Results:Compared with control group,levels of uric acid,creatinine,blood urea nitrogen and urine protein in model group were obviously increased.Both serum and renal interleukin-6,tumor necrosis factor-α and malondialdehyde in model group were significantly higher than those in control group,associated with lower activity of superoxide dismutase.At the same time,there was an apparently pathological injury discovered in model group.Compared with model group,levels of uric acid,creatinine,blood urea nitrogen and urine protein in model group were obviously decreased.Both serum and renal interleukin-6,tumor necrosis factor-α and malondialdehyde in treatment group were significantly lower than those in model group,associated with higher activity of superoxide dismutase.Simultaneously,the pathological injury obtained relief.Conclusion:Quercetin can protective kidney from renal injury induced by non-crystal hyperuricemia.And the protective effect may be associated with ability of reducing level of uric acid,antiinflammatory and antioxidative effect.
Objective To discuss the influence of operative extended rehabilitation on recovery of knee joint for patients with bone fractures around knee joint.Methods 247 patients with bone fractures around knee joint were divided into control group(n=115) and experimental group(n=132) in accordance with their hospitalization time.Conventional nursing was conducted in both two groups.In control group,there was one to two times rehabilitation treatment everyday while in experimental group,rehabilitation extended panel was established to design a specific rehabilitation plan which was implemented by both therapists and nurses all the time.The recovery of knee joint at 13th week after operation was compared.Results The recovery of knee joint of patients in experimental group was obviously better than that of patients in control group(P<0.01).Conclusion Extended rehabilitation could enhance the recovery of knee joint.
<正>包虫病是一种严重危害人类健康和畜牧业发展的人畜共患寄生虫病[1],在我国分布广泛,新疆是包虫病高发区[2]。护士对包虫病相关知识的认知状况直接决定包虫病病人的护理质量。为此,本研究拟通过问卷调查了解外科护士对包虫病相关知识的认知现状,并探讨如何提高护士对包虫病相关知识的掌握,为
目的 了解新疆地区实习护生对包虫病相关知识的认知状况及态度,为高校提高包虫病相关知识教育提供依据.方法 对在乌鲁木齐市包虫病外科治疗定点医院实习的406名护生使用自行设计的问卷进行包虫病相关知识认知状况及态度调查.结果 406名护生的包虫病知识总体得分为(14.7±2.7)分,不同民族、学历、实习科室的护生对包虫病相关知识的认知状况差异有统计学意义(P<0.05).85.2%的实习护生认为掌握包虫病相关知识有必要或非常必要,仅1.0%的实习护生对掌握包虫病相关知识重要性认识不足.结论 实习护生对包虫病的认知存在很多误区,但对掌握包虫病相关知识的态度表现积极.在护理课程的设置及临床带教上,对包虫病相关知识的教育应进一步加强.
<正>包虫病严重影响牧区群众的身体健康和生命安全,也是牧区群众因病致贫、因病返贫的重要原因之一。因此,包虫病防治及护理已成为目前提高牧区人民生活水平和医疗水平的主要任务。随着包虫病诊