Purpose: Assess the comparative accuracy and reliability of postoperative toric intraocular lens (TIOL) alignment measurement methods: Casia2 and Adobe Photoshop with digital slit lamp images (PS method).Methods: In a study of 41 subjects with 58 eyes postimplantation of TIOL, we independently measured TIOL alignment with Casia2 and PS methods. The intraclass correlation coefficient (ICC1,1) was employed to assess the repeatability of the Casia2 method. While ICC2,1 for absolute agreement and Bland-Altman analysis were utilized to determine the interdevice agreement between the two methods, the regression analysis was conducted to identify any proportional bias.Results: Casia2 demonstrated excellent intradevice repeatability with an ICC1,1 of 0.998. The absolute agreement between Casia2 and PS was very high with an ICC2,1 of 0.999. The average discrepancy between the two measurement methods was -0.828 degrees, with a 95% confidence interval (CI) ranging from -1.623 degrees to -0.032 degrees. The 95% limits of agreement (LoA) were between -6.761 degrees and 5.105 degrees, indicating a strong concordance in TIOL alignment measurements. Casia2 was capable of accurately measuring the TIOL axis alignment under conditions of pupil diameters (PDs) of 4 mm or greater.Conclusion: Casia2 and PS demonstrated significant concordance in measuring postoperative TIOL alignment, with Casia2 offering a more straightforward and accessible alternative, particularly beneficial for patients with suboptimal pupil dilation.

Purpose: Assess the comparative accuracy and reliability of postoperative toric intraocular lens (TIOL) alignment measurement methods: Casia2 and Adobe Photoshop with digital slit lamp images (PS method). Methods: In a study of 41 subjects with 58 eyes postimplantation of TIOL, we independently measured TIOL alignment with Casia2 and PS methods. The intraclass correlation coefficient (ICC1,1) was employed to assess the repeatability of the Casia2 method. While ICC2,1 for absolute agreement and Bland-Altman analysis were utilized to determine the interdevice agreement between the two methods, the regression analysis was conducted to identify any proportional bias. Results: Casia2 demonstrated excellent intradevice repeatability with an ICC1,1 of 0.998. The absolute agreement between Casia2 and PS was very high with an ICC2,1 of 0.999. The average discrepancy between the two measurement methods was -0.828°, with a 95% confidence interval (CI) ranging from -1.623° to -0.032°. The 95% limits of agreement (LoA) were between -6.761° and 5.105°, indicating a strong concordance in TIOL alignment measurements. Casia2 was capable of accurately measuring the TIOL axis alignment under conditions of pupil diameters (PDs) of 4 mm or greater. Conclusion: Casia2 and PS demonstrated significant concordance in measuring postoperative TIOL alignment, with Casia2 offering a more straightforward and accessible alternative, particularly beneficial for patients with suboptimal pupil dilation.

Introduction: To investigate the clinical characteristics and treatment outcomes of the pseudophakic eyes with malignant glaucoma (MG).Methods: This retrospective case-control study enrolled 53 eyes of 47 patients with primary angle-closure glaucoma (PACG) having cataract surgery history, including 19 patients (25 eyes) diagnosed with MG and 28 patients (28 eyes) without MG as the match. Among patients diagnosed with MG, 14 patients (18 eyes) underwent zonulo-hyaloido-vitrectomy (ZHV) and the other 5 patients (7 eyes) received conservative treatments. The visual acuity, refraction status, intraocular pressure (IOP), extent of peripheral anterior synechia, classes of anti-glaucoma medications and ultrasound biomicroscopy (UBM) examination were recorded before cataract surgery, at the diagnosis of MG and 3 months after ZHV or atropine application, respectively.Results: In the pseudophakic eyes with MG, the IOP cannot be well controlled compared to the matched eyes (27.24 & PLUSMN;8.72 mmHg vs 14.30 & PLUSMN;2.63 mmHg, P<0.001). In addition, there was a difference in the average spherical equivalent refractive error between two groups of patients (-2.23 & PLUSMN;0.84 D in MG vs -0.12 & PLUSMN;0.64 D in the matched eyes, P<0.001). By UBM analysis, the anterior chamber depth (ACD) was shallower in MG than that in the matched eyes (2.34 & PLUSMN;0.20 mm vs 3.47 & PLUSMN;0.29 mm, P<0.001). The difference between the anterior vault distance of the pseudophakic eyes with MG and that of the matched eyes was also significant (P<0.001). After treated with ZHV, the IOP was greatly decreased from 27.84 & PLUSMN;10.14 mmHg to 15.85 & PLUSMN;4.41 mmHg (P<0.001). The refractive error also changed from -2.11 & PLUSMN;0.91 D to +0.42 & PLUSMN;0.99 D (P<0.001). At the same time, the central ACD was significantly deepened from 2.30 & PLUSMN;0.39 mm to 3.30 & PLUSMN;0.31 mm (P<0.001). Conclusion: Uncontrolled IOP and shallow anterior chamber both centrally and peripherally are the primary clinical characteristics for the pseudophakic eyes with MG. An unexpected refractive error or myopic shift for the eyes with PACG after cataract surgery can be an important hint for diagnosis of MG. The typical UBM image is an anterior displacement of the lens-iris diaphragm and a bow-shaped change of the intraocular lens. It is an effective way to treat pseudophakic MG with the ZHV through a peripheral iridectomy.

Background Kimura’s disease is a rare, benign, chronic inflammatory disease that presents as painless, solid masses mainly affecting the deep subcutaneous areas of the head and neck, especially the salivary glands, parotid glands and nearby lymph nodes. It is characterized by elevated peripheral blood eosinophil and Immunoglobulin E (IgE) levels. Case presentation A 31-year-old Asian male presented with an orbital space-occupying lesion lasting for 1.5 years. Ten years prior, surgical excision of bilateral fossa cubitalis and groin masses was performed, and the pathological examination showed "lymphoproliferative disease". One year later, masses reappeared near the surgical sites; they grew slowly and shrank after glucocorticoid treatment . At this point, admission examinations showed in the peripheral blood an eosinophil proportion of 13.4%, a total IgE level of 26,900.00 IU/mL, prurigo present on the whole body, and multiple palpable masses near the bilateral fossa cubitalis and groin. The left eyeball was exophthalmic. The left elbow mass was excised, and the pathological examination confirmed Kimura’s disease. Oral glucocorticoid therapy is taken and tapering regularly. The eosinophil count returned to normal, the IgE level gradually decreased, the orbital space-occupying lesion and elbow and groin masses shrank significantly, and the whole-body skin prurigo disappeared. Currently, the patient has been in a stable condition for eighteen months. Conclusion Our case provides a novel insight that Kimura’s disease should be involved in the differential diagnosis of inflammatory lesion mass of orbit and also supports systemic regular glucocorticoid as a valuable therapy of such condition, but close follow-up and long-term observation are crucial.

目的 了解深圳市龙岗区青少年屈光状态及眼生物参数变化的变化.方法 选取深圳市龙岗区4所九年一贯制学校的四年级和初一年级进行抽样,2018年完成第一轮调查,2020年对同一调查对象进行随访.采用对数视力表、电脑验光仪及索维生物测量检测视力、等效球镜及眼生物学参数,仅纳入右眼数据进行分析.结果 与2018年比较,2020年男生、女生等效球镜和眼轴参数增加(P<0.01).2018年初一学生等效球镜、眼轴、角膜曲率及前房深度大于四年级学生;2020年两个年级学生的上述参数均高于2018年(P<0.05或0.01).2018年公立学校学生的等效球镜及眼轴均大于私立学校学生,2020年两类学校学生等效球镜及眼轴均增加(P<0.01).与2018年比较,2020年两类学校学生的角膜曲率及前房深度均有变化(P<0.01).2020年四年级学生近视率从50.2％上升至62.1％,初一学生近视率从71.0％上升至83.9％(P<0.01).2020年女生近视率高于男生,初一学生近视率高于四年级,公立学校高于私立学校(P<0.05).初一学生近视戴镜率高于四年级,公立学校学生高于私立学校(P<0.05).结论 深圳市龙岗区青少年等效球镜、眼生物学参数随年龄增长而改变,近视率也相应增加.

目的:观察中西药合用治疗出血性玻璃体浑浊的效果.方法:30例随机分为两组各15例,两组均用西药治疗,观察组加用丹参注射液治疗.结果:观察组总有效率高于对照组(P＜0.05).观察组治疗后视力高于对照组(P＜0.05),而眼压明显低于对照组(P＜0.05).观察组眼底出血、视力下降、视物模糊等不良反应发生率低于对照组(P＜0.05).结论:中西药合用治疗出血性玻璃体浑浊效果较好.

目的:对合理使用抗VEGF药物辅助治疗糖尿病视网膜病变(PDR)的治疗效果进行评价.方法:选取2017年1月—2019年12月在我院住院治疗的30例PDR患者作为研究对象,以随机分组的方式分为实验组和常规组,每组15例(患眼15眼).实验组采用视网膜激光辅以抗VEGF药物(康柏西普)进行治疗,常规组采用视网膜激光进行治疗,分析两组疗效.结果:实验组视网膜水肿恢复时间、渗出吸收时间以及眼底出血吸收时间均短于常规组;BCVA水平以及CMT水平均低于常规组;并发症发生率比常规组低;两组差异具有统计学意义(P<0.05).结论:康柏西普辅助治疗糖尿病视网膜病变能有效改善病情,值得推广.

目的 观察儿童弱视患者给予综合治疗的疗效.方法 选取我院近期接收的50例弱视患儿,根据其视力评估结果,给予综合治疗方案,观察其临床疗效.结果 弱视综合治疗的效果与患儿的弱视类型、治疗年龄密切相关.其中,屈光不正性弱视患儿的疗效最好,年龄越小的患儿,其疗效越好,P<0.05.结论 在儿童弱视的治疗中,综合治疗的疗效显著,但该症宜早发现、早诊断、早治疗,以保证患儿的视功能恢复效果.