Integrating cutting-edge technology with conventional farming practices has been dubbed “smart agriculture” or “the agricultural internet of things.” Agriculture 4.0, made possible by the merging of Industry 4.0 and Intelligent Agriculture, is the next generation after industrial farming. Agriculture 4.0 introduces several additional risks, but thousands of IoT devices are left vulnerable after deployment. Security investigators are working in this area to ensure the safety of the agricultural apparatus, which may launch several DDoS attacks to render a service inaccessible and then insert bogus data to convince us that the agricultural apparatus is secure when, in fact, it has been stolen. In this paper, we provide an IDS for DDoS attacks that is built on one-dimensional convolutional neural networks (IDSNet). We employed prairie dog optimization (PDO) to fine-tune the IDSNet training settings. The proposed model's efficiency is compared to those already in use using two newly published real-world traffic datasets, CIC-DDoS attacks.
The synthesis of thiazole linked pyrimidine and chalcone derivatives 20a-j was achieved by the Claisen-condensation reaction between thiazole-aldehyde and different types of aryl ketones in the presence of piperidine in ethanol at reflux for 12 h time. These derivatives were tested for their cytotoxicity values against MCF-7, A2780, A549 and Colo-205 cell lines with Etoposide as standard drug by utilizing MTT reduction assay protocol. Among the synthesized derivatives, the derivative 20a with 3,4,5-trimethoxyaryl ring showed superior anticancer effect on all cell lines, with IC50 values from MCF-7 = 0.05 ± 0.007 µM; A549 = 0.11 ± 0.047 µM; Colo-205 = 0.66 ± 0.062 µM and A2780 = 0.96. ± 0.075 µM. Molecular docking studies targeting human Topoisomerase IIβ revealed that several synthesized compounds, 20a, 20b, 20f, 20 g, and 20j exhibited notable binding affinities (− 5.9 to − 5.5 kcal/mol) in comparison to the standard drug Etoposide (− 6.5 kcal/mol). These candidates showed favourable interactions with critical active site residues such as GLN778, ASP479, ARG503, and MET782, which are crucial for stabilizing the topoisomerase–DNA complex. The interaction patterns suggest a potential mechanism for modulation at the protein-DNA interface. Among these, compound 20a exhibited a favourable binding and interaction profile, positioning it as a promising hit for the development of novel anticancer therapeutics.
Humanoid doctor is an AI-based robot that featured remote bi-directional communication and is embedded with disruptive technologies. Accurate and real-time responses are the main characteristics of a humanoid doctor which diagnoses disease in a patient. The patient details are obtained by Internet of Things devices, edge devices, and text formats. The inputs from the patient are processed by the humanoid doctor, and it provides its opinion to the patient. The historical patient data are trained using cloud artificial intelligence platform and the model is tested against the patient sample data acquired using medical IoT and edge devices. Disease is identified at three different stages and analyzed. The humanoid doctor is expected to identify the diseases well in comparison with human healthcare professionals. The humanoid doctor is under-trusted because of the lack of a multi-featured accurate model, accessibility, availability, and standardization. In this letter, patient input, artificial intelligence, and response zones are encapsulated and the humanoid doctor is realized.
Purpose The study aims to focus on the necessity for advanced transformational leadership and integration of technology in accomplishing sustainable goals through proactive, innovative approaches to thrive in a complex and environment-conscious world. The integration of metaverse technological adaption and information technological capabilities marks a significant evolution beyond traditional models; enhances the strategies and practices of organizations. Design/methodology/approach The three-wave study design included 448 IT leaders (CEOs, Directors and Managers) in India, Bangladesh, Bhutan and Indonesia. The data was analyzed using PLS-SEM 4 (v4.0.9.9) software. Findings The results suggest that green transformational leadership (GTL) positively influence green organizational agility (GOA). There is a positive relationship between GTL and GOA through green human resource management practices (green training and development and green compensation and rewards). Information technology capabilities of the leaders help in moderating organizational innovativeness and through this metaverse adoption moderate organizational agility. Research limitations/implications The innovative application of upper-echelon theory builds up a fresh perspective on leader’s role in the organization by shifting the emphasis from traits to attitudes influencing effectiveness in promoting green culture. Adopting metaverse in the organizations would help leaders in operationalizing flexible culture and managerial support. This helps employees in fostering team cohesion, feeling of belongingness enhancing productive culture through innovativeness. Originality/value The study provides novel perspectives of using metaverse adoption in organizations, where leaders approach comprised of traits, capabilities and attitudes toward organizational agility are studied.
Seaweeds have emerged as one of the most commercially important marine resource that harbours industrially relevant bioactive compounds such as polysaccharides, proteins, dietary fibres, minerals, pigments, polyphenolic compounds etc. This in turn has fostered an extensive research on extraction of seaweed based high value compounds. Conventional methods which were popularly used for extraction of seaweed bioactive compounds are being replaced by advanced “greener” techniques such as supercritical fluid, eutectic solvents, microwave, enzymatic, ultrasound assisted extraction etc. Among all sustainable techniques, ultrasound assisted extraction (UAE) is the most economical method for seaweed biovalorization. Employing ultrasonic waves aids in effective disruption of seaweed cell walls facilitating higher extraction rate in short period of time. Judicious integration of UAE with other efficient extraction systems are reported to yield several high value added products such as phenolic compounds, hydrocolloids, biochar, hydrochar, fertilizers, seaweed based biostimulants, biofuels, feeds etc. and hence can pave way towards establishment of successful seaweed biorefineries. The core aim of the present review is to give a comprehensive understanding of the principles and application of UAE in seaweed biovalorization by enhancing the recovery of different biomolecules when used as a major process or as a pre or post treatment step. Furthermore, the advantages, challenges and drawbacks of UAE in comparison with other extraction processes is also discussed in detail.
