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Substantial disposal of stone dust waste produced from quarry industries is of crucial concern. Besides, many lateritic soils were inappropriate in engineering work owing to their unfavourable properties. Also, there is the need to study up to microstructural level of stone dust treated lateritic soils. Thus, this study evaluates the effects of compactive efforts on lateritic soil stabilized with stone dust as well as its microstructural characteristics. The lateritic soil (LS) samples were stabilized with stone dust (SD) at 0–30 wt
Abstract Most cases of malaria, one of the most dangerous and common tropical parasite infections, occur in developing nations. Recent years have seen the emergence of novel treatment techniques, and numerous medication candidates are currently undergoing clinical research. One noteworthy outcome of combining an artemisinin derivative with a companion medication (in this case, mefloquine) using an alternative method of action is that it inhibits the growth of medication resistance and stops the spread of P. falciparum. Resistance to currently available antimalarial drugs is prevalent due to several factors, including the rate of parasite mutation, the total parasite load, the potency of the chosen drug, treatment compliance, inadequate adherence to malaria treatment guidelines, incorrect dosing, poor pharmacokinetic properties, and the use of low-quality antimalarials that may contribute to and exacerbate resistance. There are three types of malaria vaccinations: blood-stage vaccines, erythrocytosis-mimicking vaccines, and vaccines that stop the disease from spreading. This article examines various approaches to creating antimalarial medications in an attempt to solve the problem of drug resistance.
Processing conditions have significant effects on mechanical oil expression from oleaginous seeds and kernels. It affects both the quantity and quality of oil, and the failure to optimise the process can result in poor yields and reduced quality, thereby limiting the potential for using oil in industries. The aim of the study was to model and optimise the impact of moisture content (MC), roasting time (RT), and heating temperature (HT) on the oil yield, extraction efficiency, and quality attributes of mechanically expressed African oil bean oil, based on soft computing technology. During oil expression using a mechanical oil expeller, MC (8–16
Persuasive strategies, a rhetorical means deployed in investigative interactions by investigating officers and suspects to influence each other's behaviour, have received moderate scholarly attention, especially in police-suspect interactions. Consequently, not much attention has been paid to the use of these strategies in interactions involving the Nigeria Security and Civil Defence Corps (Civil Defence) and Civil and suspects. Data were obtained from the Headquarters of the Oyo State Command of the Civil Defence. The data were bound using Gotti's principles of persuasion in discourse theory. The analysis demonstrates that IOs and suspects employ pathos and logos as rhetorical devices for persuasion.
In the constantly evolving realm of blood-based fluid dynamics, meticulous management of thermal and fluidic properties within living organisms is crucial for advancing diagnostic and therapeutic applications. This study focuses on the complex interactions within a Casson hybrid nanofluid comprising ferrosoferric oxide (Fe3O₄) and molybdenum disulfide (MoS₂) nanostructures dispersed in blood plasma. The research explores the influence of thermal diffusion, diffusion-thermo, and non-linear (quadratic) thermal radiation on the fluid’s transportation dynamics, while taking into account sophisticated boundary conditions such as the Smoluchowski temperature jump and the Maxwell velocity slip. These boundary conditions closely replicate physiological environments at the micro/nanoscale. The governing PDEs that describe the flow of the nanomaterial are transmuted and parametrized through a similarity transformation. These resulting equations are simulated by utilizing the finite difference method to ensure numerical stability and accuracy. The results suggest that both variants of nanomaterials substantially improve thermal conductivity and energy transfer, with temperature and velocity distributions being influenced by temperature jump and velocity slip conditions. Moreover, thermal diffusion and diffusion-thermo processes result in a decrease in temperature and an increase in velocity and concentration. This study presents an advanced physics-driven framework for the development of biomedical devices and fluid-based therapeutic systems.
