Photocatalytic water splitting is a promising route for solar-tohydrogen conversion, but organic photocatalysts are often limited by strong exciton binding, rapid charge recombination, inefficient carrier transport, and sluggish proton-reduction kinetics....
Supramolecular poly-(4-vinylpyridine) complexes were developed as a materials platform for soft plasma etching. Etch rate can be significantly enhanced while maintaining homogeneous etching between the polymer and complexing molecule. This...
Targeted imaging of VEGFR holds great promise for both diagnostic and therapeutic applications. Herein, we reported the development of a sulfonyl-γ-AApeptide-based peptidomimetic radioligand acting as an antibody surrogate for VEGFR-targeted...
Synthetic self-assembling peptides (SSAPs) can produce extracellular matrix (ECM)-like hydrogels with tailored properties. We report on the Young’s modulus of two peptide amphiphiles C 16 V 3 A 3 K 3 (K3) and C 16 V 3 A 3 E 3 (E3) across multiple...
We constructed a CRISPR/Cas12a autocatalytic system based on miRNA-triggered overhang blocker (OB) cleavage-recombination framework, in which Cas12a sequentially removed steric hindrance to initiate cyclic autocatalysis, enabling exponential signal amplification for...
Herein, a high-entropy alloy electrocatalyst (RuNiFeCoMn/NC) is synthesized with outstanding oxygen reduction reaction (ORR) activity in alkaline media. It enables a high peak power density of 192 mW cm⁻² with...
Electrochemical CO2 reduction (CO2RR) to C3+ products offers an attractive route for producing valuable long-chain fuels and chemicals. However, direct CO2-to-C3+ conversion remains substantially challenging because it requires concerted control...
A bulk-interface synergy strategy through Ca doping in the bulk layer and Pr-based surface modification for NaNi1/3Fe1/3Mn1/3O2 were developed in this work to overcom its sluggish electrochemical kinetics, which limits...
Sonodynamic therapy (SDT) has emerged as a promising non-invasive cancer treatment. By employing low-intensity focused ultrasound, SDT activates sonosensitizers to produce cytotoxic reactive oxygen species (ROS), enabling selective tumor cell...
Isoxazoles are versatile N,O-containing five-membered heterocyclic building blocks widely utilized in the construction of chiral pharmaceutical intermediates. Over the past two decades, tremendous progress has been made in their catalytic...
High-temperature in situ electrochemical activation method is developed to achieve the maximum capacity of V₂O₅ within only two charge-discharge cycles. High-temperature electrochemistry accelerates the dissolution-recrystallization process of V₂O₅, providing a...
We employ femtosecond transient absorption spectroscopy to probe ultrafast charge transfer at the CO2 reduction interface in situ. We uncover hitherto unrecognized chemisorption states, formed through orbital hybridization between chemisorbed...
We report the synthesis of two rim-differentiated pillar[5]arene dithiol isomers: the adjacent (A1/B1) and non-adjacent (A1/C1) derivatives. These two isomers lead to completely divergent disulfide-based dynamic covalent library outcomes. While...
A direct dearomative cascade annulation of unactivated pyridines has been achieved using a Brønsted acid, enabling efficient access to indolizin-5(3H)-one frameworks. The transformation proceeds through a sequential [2+2] cycloaddition, followed...
Stimuli-responsive polymer assemblies possess numerous advantages for medicine because they combine the synthetic versatility of macromolecules with the specific functions of self-organized soft matter. However, the biomedical performance of these materials cannot be fully understood solely from the change in properties of the stimulus-responsive component as a response to an external trigger. The decisive variables are structural: morphology, aggregation number, membrane or core mobility, interparticle ordering, concentration-dependent phase behavior, and the kinetics with which assemblies form, exchange chains, reorganize, or disassemble. In this feature article, we view the field through a structure-to-function lens, in which pH, temperature, redox or reactive oxygen species, ionic strength, and related inputs are treated as regulators of supramolecular state rather than simple 'on-off' switches. The focus spans responsive nanomedicines and theranostic systems, the physical chemistry of block copolymer micelles and polymersomes, and the concentration-dependent rheology and ordering of medically relevant assemblies. We show in this review how progress in responsive polymer medicine increasingly depends on understanding interference among triggers, non-equilibrium self-assembly, and characterization under realistic formulation and biological conditions.
B,N,O-co-doped carbon dots with dual fluorescence-phosphorescence are prepared. Blue LEDs achieve an external quantum efficiency (EQE) of 6.01%, exceeding the fluorescent limit, and white LEDs deliver 4.18% efficiency with good colour stability.
Metal nanoclusters (NCs) have emerged as promising materials for environmental applications due to their atomically precise structures and tunable physicochemical properties. Controlled synthetic strategies-including bottom-up methods, and post-synthetic modifications such as ligand and metal exchange-enable precise regulation of their size, composition, and surface chemistry. These features impart unique optical and catalytic properties, making metal NCs highly effective for environmental monitoring and remediation. Their strong and tunable photoluminescence enables sensitive and selective detection of pollutants such as heavy metal ions, toxic anions, organic contaminants, and volatile compounds. In addition, metal NCs exhibit excellent catalytic activity in processes such as CO2 reduction, nitrate conversion, pollutant degradation, and photocatalytic hydrogen production. This review highlights recent advances in the synthesis of metal NCs and emphasizes their growing role in addressing critical environmental challenges through sensing and catalytic applications.
A synergistic strategy was developed for anode-free sodium metal batteries by integrating a dual-salt electrolyte with mesoporous hollow carbon nanotubes. The electrolyte formed robust SEI/CEI layers to regulate ion flux and stabilize electrodes, while Meso-CNTs provided sodiophilic sites, enhanced ion/electron transport, and mitigated volume variation. This synergistic design enabled reversible Na deposition and stable cycling, offering an effective approach for durable high-energy-density sodium metal batteries.
An organometallic chelated layer was uniformly coated on Zn metal. The hydrophobic polydimethylsiloxane suppresses H2 and byproduct generation, while metal coordination sites improve ionic conductivity and guide uniform Zn plating/stripping, inhibiting Zn dendrite formation. Thus, the symmetric cells of modified Zn cycle over 3400 h at 1 mA cm-2/1 mAh cm-2.
We report a class of phenoxazine-based organic small-molecule fluorophores synthesized in four steps, achieving peak emission beyond 1300 nm with molecular weights <600 Da, among the lowest reported to date. This compact and concise synthetic strategy provides new fluorophores for the shortwave infrared (SWIR) region, which offer potential feasibility for overcoming metabolic barriers and provide a structurally compact scaffold for future deep-tissue imaging applications.
