Objective: To study the significance of hemorheology and serum sICAM-1,sVCAM-1,IGF-1,ALP levels in patients with delayed fracture healing.Methods:A total of 78 patients with fracture treated in our hospital from June 2010 to September 2012 were selected in this study,of which 39 that had normal fracture healing were assigned as control group,other 39 cases that showed delayed fracture healing as observation group.The hemorheology and serum sICAM-1,sVCAM-1,IGF-1,ALP levels of two group 1,4 and 8 weeks after the fracture were observed and compared.Results:One week after the fracture,the hemorheology and serum sICAM-1,sVCAM-1,IGF-1,ALP levels of two groups were not significantly different from each other(P0.05),but 4 and 8 weeks after the fracture,blood viscosity indexes and erythrocyte related indexes of hemorheology and serum sICAM-1,sVCAM-1 of observation group were all higher than those of control group,while serum IGF-1 and ALP were lower than those of control group(P all0.05).Conclusion:The hemorheology and serum sICAM-1,sVCAM-1 of patients with delayed fracture healing show an increasing trend,while the serum IGF-1 and ALP are lower,which may contributes to the delayed fracture healing.

目的:观察四妙丸加减治疗腰椎间盘突出症湿热证的疗效。方法:临床选取腰椎间盘突出症湿热证的病人48例,分别采用四妙丸和对照药物治疗。结果:采用四妙丸治疗腰椎间盘突出症湿热症常规服药3个疗程,总有效率88.9%。结论:四妙丸治疗腰椎间盘突出症湿热症临床上效果好于对照组。

Objective:To evaluate the effects of interlocking intramedullary nail in treating distal femoral fracture.Methods:A total of 90 cases with distal femoral fracture were randomly divided into experimental group and control group by half.Cases in experimental group were treated by interlocking medullary nail while cases in control group were treated by locking compressing plate.The surgery time,volume of blood loss during surgery,healing time and incidence of post operational complication were observed and compared.Then a 6-18 month follow-up was carried out,averaged 12 months.Results:Experimental group showed longer surgery time,less bleeding volume,and shorter healing time(P0.05).The excellent and good rate was significantly higher in experiment group(91.1%vs 73.3%)(P0.05).Conclusions:With less bleeding volume and shorter healing course,interlocking intramedullary nail is more effective than locking compression plate.

Objective:To observe the preventive effect of Danhong Injection(DI) on deep vein thrombosis(DVT) in lower limbs of patients after total hip replace-ment,(THR).Methods:Ninety qualified patients who were going to take THR were equally randomized into the treatment group and the control group.The two groups were given peri-operative conventional therapy and routine nursing method,and the treatment group was given DI additionally.After THR,the occurrence of DVT,and symptoms and signs were observed.Bleeding volume during the operation,and postop-erative drainage volume from the wound were recorded.Hemoglobin content and platelet count as well as the adverse reaction of drugs were monitored 14 days after op-eration.Results:DVT occurred in 8 patients(17.8%) of the treatment group,and in 19(42.2%) of the control group,the difference being significant between the two groups(P>0.05).In the treatment group,bleeding volume during the operation was(389±72)mL,postoperative drainage volume from the wound was(248±65)mL,hemoglobin content was(103±15)g/L and platelet count was(210 ±25)×109/L.In the control group,bleeding volume during the operation was(385 ±72)mL,postop-erative drainage volume from the wound was(247±64)mL,hemoglobin content was(100±I5)g/L and platelet count was(209±25)×109/L.The differences of the above four parameters were insignificant between two groups(P> 0.05).Conclu-sion:DI is effective and safe on decreasing the incidence of DVT in lower limbs of patients after total hip replacement.

疼痛、肿胀、功能障碍是踝关节损伤主要面临的常见问题,通过分析推拿对踝关节损伤疼痛、肿胀、功能障碍的影响及临床运用,指出推拿可以用于踝关节损伤的治疗,并为进一步进行科学的临床总结和机理探讨提供思路和途径。