Objective:To explore the influence to blood glucose control and cardiovascular events of Liuwei Dihuang Pill in treatment of type 2 diabetic patients with coronary heart disease.Methods:The clinical data of 80 cases of type 2diabetic patients with coronary heart disease in our hospital were selected as the research objects and they were randomly divided into observation group and control group and each 40 cases.The control group were treated with conventional aspirin,clopidogrel,statins and conventional hypoglycemic agents and the observation group were given Liuwei Dihuang Pills on the basis of the control group.Blood glucose control and cardiovascular events (acute myocardial infarction,angina,coronary artery bypass,and death) were compared between the two groups.Results:There was no significant difference in fasting blood glucose level between the two groups (P ＞ 0.05).The fasting blood glucose level of the patients in the observation group during the treatment was (7.69 ± 0.24)mmol/L and after the treatment (6.32 ± 0.19)mmol/L,obviously lower than (8.10 ± 0.18)mmol/L and (7.69 ± 0.20) mmol/L of the control group.There was significant difference between the two groups (P ＜ 0.05).The incidence of acute myocardial infarction,angina,coronary artery bypass surgery and other cardiovascular events in the observation group was significantly lower than that in the control group and there was significant difference between the two groups (P ＜ 0.05).Conclusion:Liuwei Dihuang Pills in treatment of type 2 diabetic patients with coronary heart disease can effectively reduce the blood sugar level of patients,control blood glucose stability and effectively reduce the incidence of cardiovascular events.For the treatment of patients with type 2 diabetes mellitus with coronary heart disease,Liuwei Dihuang Pills have important clinical significance,with better safety and practicality,worthy of further clinical application.

目的通过在泌尿外科开展品管圈活动,降低出院患者口服药的剩余率,降低患者费用,保障患者的用药安全。方法利用品管圈的各种手法,进行原因分析,提高工作质量。结果住院患者出院时口服药剩余粒数为45.7粒/w,下降到活动后6粒/w。结论通过推行品管圈的活动,不断提高泌尿外科的质量管理,更好为患者服务。

Objective: To investigate the mechanism and efficacy of Chinese patent medicine combined with Silibinin on the alcohol- induced liver disease. Methods: 68 cases with alcoholic liver disease in our hospital were used. All of them were divided into two groups. 34 cases in the control group were treated with Chinese patent medicine and the study group used Silibinin on the basis of the control group. The curative effects were observed after two courses ' continuous treatment. Results: The total effective rate of the study group was 88. 24%,significantly higher than 73. 53% in the control group and the difference was statistically significant( P 0. 05). The two groups' liver functions including ALT,AST,T- BIL and blood TC,TG levels were significantly decreased than before,and the degree of decline of the study group was higher and the difference was statistically significant( P 0. 05). Conclusion: Chinese patent medicine combined with Silibinin used on the alcohol- induced liver disease has a significant effect,worthy of clinical application.

目的探讨抗生素相关性肠炎的成因及治疗。方法通过查阅各类相关资料综合叙述抗生素相关性肠炎产生成因从而总结出目前主要治疗方法为临床治疗提供理论性依据。结果几乎所有的抗生素均能引起AAC的发生,其治疗应从多方位入手方可取得良好疗效。结论临床药师应利用所掌握的药学知识,充分发挥自己的业务专长,积极参与到临床药物治疗中,尽最大可能预防抗生素滥用所致的抗生素相关性肠炎以确保药物治疗安全有效。

目的讨论不同治疗方案治疗下呼吸道感染的药物的成本-效果。方法将120例下呼吸道感染患者随机分为阿奇霉素静脉滴注(A组)、莫西沙星静脉滴注(B组)、头孢曲松静脉滴注(C组),对3种方案进行药物经济学成本-效果分析。结果 A、B、C组成本分别为:716.10、2014.60、679.70元;有效率分别为:85.00%、93.00%、82.00%;成本-效果比分别为:8.40、21.66、8.29。结论 3种抗菌药物方案治疗下呼吸道感染B组方案较好。

目的建立左旋多巴片微生物限度检查方法并对其进行验证。方法按照《中国药典》2010年版二部附录微生物限度检查法试验,采用阳性试验菌,用3种方法测定回收率。结果左旋多巴片具有抑菌作用,确定了左旋多巴片微生物限度检查的最佳操作方法。结论细菌总数测定用离心法和薄膜过滤法联用,霉菌和酵母菌总数测定采用常规法,控制菌检查用经验证的常规法。

总结阿司匹林与非甾体抗炎药之间的相互作用,探讨其他非甾体抗炎药物对阿司匹林抗血小板作用影响以及这些作用带来的风险。提出阿司匹林和其他非甾体抗炎药药物合用时应谨慎,避免心血管事件的发生以及不良反应的加重。

目的了解药品不良反应的发生特点及一般规律,促进临床合理用药。方法对医院2009年120份不良反应报告进行分类统计和分析。结果涉及不良反应的药品共5大类,其中抗感染药物90例,占75.00%;所发生的不良反应累及全身多个系统,以皮肤及其附件损害居首位,共81例,占67.50%。结论药品不良反应的发生在临床上难以完全避免,但可以通过科学有效地开展不良反应监测,健全监督管理机制和技术规范,尽量避免或减少其发生。

目的比较国产与进口氨氯地平治疗原发性高血压的成本-效果。方法将95例门诊高血压患者随机分为A、B两组,分别给予施慧达(国产)2.5mg和络活喜(进口)5mg晨服,治疗8周,观察疗效、记录不良反应,并进行成本-效果分析。结果两组治疗前后均有明显的降压效果,组间无显著性差异,但成本差异明显。结论国产比进口氨氯地平有较好的成本-效果比。

OBJECTIVE To investigate the clinical effect of inhalation of asarone mixed with pulmicort respules on children with bronchiolitis.METHODS 82 children with bronchiolitis were randomly divided into control and treatment group.The two groups were received basical therapy of anti-infection,oxygen inhalation and sputum suction.The treatment group was assist-treated with inhalation of asarone mixed with pulmicort respules, and the control group were assist-treated with aminophylline.The clinical efficacy and time of symptoms duration were observed.RESULTS The effective rate of the treatment group was higher and the time of symptoms duration was shorter than that of the control group,with significant difference.CONCLUSION Inhalation of asarone mixed with pulmicort respules may alleviate the symptom of dyspnea and shorten the hospitalization time for patients with bronchiolitis.It is worthwhile to be widely used for its remarkably effect and safety.

目的探讨3种联合给药方案治疗良性前列腺增生(BPH)所产生的成本-效果比。方法选择我院门诊中重度良性前列腺增生患者75例,随机分为3组,分别给予非那雄胺加坦索罗辛(A组),多沙唑嗪加普适泰(B组),特拉唑嗪加普适泰(C组),运用药物经济学方法进行分析。结果3组成本分别为832.16、785.12、524.16元。有效率分别为88%、80%、76%。效果-成本分别为9.46、9.82、6.90元。结论A组联合给药方案治疗良性前列腺增生成本-效果比最佳。

目的探讨提高药学咨询服务质量的方法与技巧。方法对我院门诊药学咨询工作记录进行回顾性总结与分析。结果我院患者及其家属咨询人数较多,心血管病人药学咨询次数最多,咨询内容广泛。结论开展药学咨询服务是提高药学服务技术含量的有效途径,加强临床药师培训、配备计算机药学查询系统有利于提高药学咨询服务质量。

目的探讨如何做好当前医院门诊药房药学服务与管理改进。方法结合实际,参考其他医院做法。结果做好新形式下医院门诊药房药学服务与管理改进工作主要从以下6个环节入手:数字化信息运用;优质、高效、有特色的药学服务;树立以患者为中心的服务理念;社区化药学服务;设立责任药师制;实行绩效考核管理。结论认真做好6个环节的工作,提供优质的药学服务。

目的了解我院麻醉药品的应用情况。方法采用微机统计麻醉药品应用情况进行分析。结果与结论目前在麻醉药品使用中存在不合理现象,须进一步改进,以便更好的执行“癌痛三阶治疗指导原则”。

通过开展药学服务,使药师能够应用自身的专业知识,服务于医生、护士、患者及家属。真正地实现以“病人为中心”的服务理念。提高病人用药的依从性,最大限度地发挥药物的疗效,从而提升药师在广大群众心目中的地位。

目的观察定君生胶囊治疗孕妇复发性念珠菌性阴道炎的应用价值。方法随机选取120例复发性念珠菌性阴道炎妊娠的妇女,达克宁栓治疗作为对照组(n=60),每天1次400mg阴道用药,连用6d;采用定君生胶囊和达克宁栓联合治疗作为治疗组(n=60),达克宁栓每天1次400mg阴道用药,连用6d,而后采用定君生胶囊每天1次0.25g,阴道用药,连用10d。于用药第一、三个月后复查并比较两组疗效。结果治疗组的治愈率为95%,对照组的治愈率为83%。两组疗效有显著差异,两组复发率分别为7.4%和22%,差异有显著性(P<0.05)。结论定君生胶囊和达克宁栓联合治疗孕妇复发性念珠菌性阴道炎具有显著疗效。

目的比较3种药物治疗抑郁症的成本-效果。方法将符合抑郁症诊断标准的门诊患者共60例随机分为A组(给予文拉法新治疗)、B组(给予马普替林治疗)、C组(给予氟西汀治疗),每组20例,3组均口服给药,疗程6周,应用药物经济学成本-效果分析方法进行评价。结果A、B、C 3种方案的总成本依次为319.72,299.88和483.00元,痊愈率分别为50.0%,35.0%和40.0%,有效率分别为75.0%,70.0%和75.0%。结论A方案痊愈率、有效率的成本-效果比均最低,不良反应较少,为最佳治疗方案。

目的了解复方丹参注射液的不良反应的发生情况并分析相关因素。方法对清华学术期刊网上19 9 7~2 0 0 6年53篇69例丹参注射液的不良反应病例按性别、年龄、发生时间和ADR类型进行分类统计和分析。结果复方丹参注射液所致不良反应与给药剂量,给药途径无显著关联,与给药速度和联合用药有关。主要集中发生于给药数分钟内,男性多于女性,可累及多个器官系统,临床表现复杂多样。

目的分析降糖药在我院的应用情况。方法采用计算机统计2004年~2005年降糖药的用量,品种及数据比较。结果与结论在临床应用中多以α-葡萄糖苷酶抑制剂为主导地位。磺脲类格列齐特控释片用量上升较快,降糖药的用量逐年增长,提示人们在生活水平提高的前提下应注意身体的保健。

目的探讨雄黄酊治疗带状疱疹的疗效。方法用雄黄和75%乙醇调成糊状外敷于带状疱疹处。结果38例带状疱疹全部痊愈。结论雄黄酊治疹带状疱疗方法简单,效果好,经济实惠。