王京奇主任医师认为,咳嗽变异性哮喘病性为本虚标实,病位以肺为本,肝脾肾互参,病因以"风"为因,痰瘀虚兼顾,病机为"风"邪犯肺,气道挛急,肺气上逆.临床治疗需从标本论治,分期治疗,发作期是内外风协同致病,治疗以疏风解痉为主,肝肺同治,以"祛风止咳汤"加减治疗,缓解期以虚为本,治疗以扶正固本为主,肺脾肾同调,以脾胃为本,肺肾同补.

恶性肿瘤作为临床常见的一种心身疾病,与情志因素密切相关.本文从中西医两个角度对肿瘤的发生与情志之间的关系进行介绍,对肿瘤、伴发症状,以及治疗中引发的各种情志变化进行阐述,并对情志影响恶性肿瘤的机理进行分析,对临床常用的干预方法进行总结.提示不良的情志会加剧肿瘤的进展,而良好的情志有助于病情的稳定乃至患者长期生存.

对王京奇老中医的肝病学术思想进行总结,包括学术渊源、学术思想和学术特点.其中学术渊源主要从王老师跟师学习杨润芳和关幼波的角度,梳理王老师学术思想的来源和演变过程;学术思想概括为辨病辨证相结合,体用关系不可偏,阴阳气血共为纲,肝、胆、脾、肾宜同参,心身二维一体化,古今并重等齐观;学术特点从病证方药成体系,用药轻灵重气机,对角串药及套方,正邪虚实首健脾的角度进行论述,旨在总结传承王老师的肝病学术思想.

Objective To observe the clinical effect of Sisheng-jiangzhi-shugan decoction on the treatment of nonalcoholic fatty liver disease (NAFLD) of phlegm-wet resistance type.Methods 60 NAFLD patients with phlegm-wet resistance type were treated by Sisheng-jiangzhi-shugan decoction on the basis of basic treatment, continuously treatment for 3 months.The height, body mass, waist and hip circumference were measured,body mass index (BMI) and waist circumference/hip circumference ratio (WHR) were calculated.The blood lipid indexes including total cholesterol (TC), triglycerides (TG), low density lipoprotein (LDL-C), high-density lipoprotein cholesterol (HDL-C) were detected.The fasting plasma glucose (FPG) and fasting insulin (FINS) were detected, and the homeostasis model assessment insulin resistance index (HOMA-IR) was calculated.The liver function including alanine aminotransferase (ALT), aspartic aminotransferase (AST) and γ-glutamamide transferase (γ-GT) and the creatinine (Cr) of Kidney function were detected.Results After treatment with Sisheng-jiangzhi-shugan decoction, the clinical symptoms and signs were improved with different degree of the majority patients.The fecal viscous, swell and stuffy of the right rib and loss of appetite had most significant improvements.The WHR after 1,3 months treatment were reduced, and which after 3 months treatment was lower than that after 1 month treatment (P<0.01).The TC, TG, LDL-C and HOMA-IR after 1 and 3 months treatment were reduced (P<0.05,P<0.01), and the HDL-C was increased (P<0.01).The TC, TG, LDL-C and HOMA-IR after 3 months treatment were lower than that after 1 month treatment (P<0.05, P<0.01), and the HDL-C was higher (P<0.01).The total effective rate was 87.5%.Conclusion Sisheng-jiangzhi-shugan decoction canimprove the clinical symptoms and promote lipid metabolism on the treatment of NAFLD of phlegm-wet resistance type.

周围性面瘫是针灸科常见病种之一,临床上治疗方法多种,但效果不一.为了研究“贺氏三通法”对周围性面瘫疗效,现总结2005年-2015年中国知网中关于“贺氏三通法”治疗周围性面瘫的临床报道,并按温通、强通、微通及综合治疗、分期治疗进行论述.通过总结说明采用“贺氏三通法”分期治疗周围性面瘫较单一治疗方案疗效好.急性期尽早联合采用贺氏强通法、微通法是本病快速、完全恢复的关键.

Objective To observe the therapeutic effect of the Heshi Santong Way staging treatment of peripheral facial paralysis. Methods The October 2013 - October 2014 Mentougou District of Beijing Traditional Chinese Medicine Hospital acupuncture clinic of peripheral facial paralysis were 80 cases and they were randomly divided into observation group (60 cases) and control group (20 cases). Early observation group was Wei Tong and Qiang Tong, recovery simply to Wei Tong method, sequelae mainly treated to Wen Tong. The control group was ipsilateral facial cents acupuncture, acupuncture mild early, middle and late slightly stronger stimulus, with the contralateral HeGu. 2 groups were leaving the needle 30 min, 5 times a week for treatment until cured, not cured of the observation time of three months. Results Cure rate in the observation group and the control group group was 62.5%and 50.0%, respectively, as a significant difference (χ2=8.470, P<0.01). Observation group and control group in the first stage treatment time was significantly shorter than the second stage, statistical comparisons were different (Observation group t = 4.871,P<0.01; control group 4.645, P<0.001). The observation group and the control group in the first stage, second stage, third stage, the fourth stage of healing time were significant differences (t=2.990, P<0.01;t=2.735,P<0.05;t=3.382 ,P<0.01;t= 2.224, P<0.05), the observation group healing time was shorter than the control group. Conclusion The application of Heshi Santong way staging treatment of peripheral facial paralysis with obvious therapeutic effect, and early treatment effect is better.

Objective In this study,the promotion and management mode of the appropriate technology of TCM were explored. Methods On the basis of the training to the 2A hospital provided by the 3A hospital,and the training to the community service center provided by the 2A hospital. Results The study results showed that according to the questionnaire on the satisfaction of the third independent part,the clinical value was 100% for the physicians in Beijing Mentougou TCM Hospital and in Beijing Mentougou Community Service Center. Conclusion This promotion Management Mode is an excellent mode of the appropriate technology of TCM.

朴炳奎教授认为,结直肠癌为本虚标实之证,本虚在于脾胃虚弱、气血亏虚、肝肾阴虚、脾肾阳虚,标实在于湿热内蕴、瘀毒内结.治疗方面以健脾益肾、行气化湿、解毒抗癌为主,且须根据不同时期辨证施治.

[目的]探讨苏木对人肺癌PG细胞增殖、黏附、侵袭能力的影响.[方法]分别于常氧和低氧环境中培养细胞,苏木提取液作用PG细胞后,MTT法检测细胞增殖、流式细胞术检测CD29表达水平、Transwell小室侵袭实验检测细胞侵袭能力.[结果]作用48h后,低氧环境下不同浓度苏木作用后的PG细胞增殖速度高于常氧环境(P＜0.05).CD29表达水平在各实验组之间均有差异(P＜0.05),中、高浓度苏木与对照组比较有明显的抑制作用(P＜0.05).在常氧和低氧环境中,高、中、低浓度苏木组对PG细胞的侵袭能力均有抑制作用.[结论]苏木对PG细胞的增殖、黏附及侵袭有抑制作用.

Traditional Chinese medicine(TCM) holds that many tumors in the advanced stage show the symptom of blood stasis,so blood circulation by removing blood stasis method becomes important treatment for advanced malignant tumors. Experiments in vivo and in vitro shows sappan wood antitumor effect and the research at home and abroad are introduced. Sappan wood and other promoting blood circulation to remove blood stasis mechanism of inhibiting tumor were analyzed to provide basis for clinical medicine for activating blood circulation antitumor.

The ancients have expounded long ago the difference between ancient and current formulas from dosage,varieties,quality,decocting and taking of Chinese medicinal,but there are still shortages.The authors introduced and compared in detail,combining ancients' opinions and individual understanding, the ancient and current formulas from the aspects of nature,quantity,administration,varieties and quality of Chinese medicinal.